[en] Abstract<jats:label/>Dementia risk is influenced by the social conditions in which people live. These social determinants of dementia (SDOD) are potential targets for prevention. We conducted a comprehensive scoping review to identify current evidence on SDOD in two stages: (1) review of systematic reviews on SDOD; and (2) review of primary literature to address identified gaps in the evidence base. Of the 3445 articles screened, 26 reviews and 74 primary studies were included. Evidence from reviews provide clear and consistent patterns for some SDOD (e.g., education, air pollution, socioeconomic status, ethnicity), while evidence for others is still emerging (e.g., housing quality/stability), or lacking entirely (e.g., incarceration). SDOD are important over the life course. Additional evidence is needed for understudied domains and to unravel the complex interactions between determinants, whilst education and air pollution stand out as key targets for public health interventions.Highlights<jats:list list-type="bullet">
<jats:list-item>There is clear and consistent evidence for some social determinants of dementia (SDOD) across diverse domains.</jats:list-item>
<jats:list-item>Evidence for other SDOD (e.g., housing, incarceration) is still emerging or lacking.</jats:list-item>
<jats:list-item>Evidence for SDOD comes mainly from high‐income countries.</jats:list-item>
<jats:list-item>The complex intercorrelations between SDODs demand a nuanced analytical approach.</jats:list-item>
<jats:list-item>Standardized measures and longer follow‐up to study SDOD are recommended.</jats:list-item>
Precision for document type :
Review article
Disciplines :
Sociology & social sciences Public health, health care sciences & services Neurology Psychiatry Neurosciences & behavior
Author, co-author :
Walsh, Sebastian ; Cambridge Public Health University of Cambridge, Forvie Site Cambridge UK
KLEE, Matthias ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences > Department of Social Sciences > Team Anja LEIST ; Department of General Internal Medicine and Psychosomatics University Medical Centre Heidelberg Heidelberg Germany
Hui, Esther K.; Division of Psychiatry University College London London UK
Saeed, Usman; Institute of Medical Science Temerty Faculty of Medicine University of Toronto Toronto Ontario Canada ; Hurvitz Brain Sciences Program Sunnybrook Research Institute Toronto Ontario Canada
Waters, Sheena; Centre for Preventive Neurology Queen Mary University of London London UK
Kuhn, Isla; Cambridge Public Health University of Cambridge, Forvie Site Cambridge UK
Siette, Joyce; The MARCS Institute for Brain Behaviour and Development Western Sydney University Westmead NSW Australia
Orgeta, Vasiliki; Division of Psychiatry University College London London UK
Stafford, Jean; Advanced Care Research Centre University of Edinburgh Edinburgh UK
Smith, Laura J.; Centre for Preventive Neurology Queen Mary University of London London UK
Tamburin, Stefano; Department of Neurosciences Biomedicine and Movement Sciences University of Verona Verona Italy
Jensen, Daria E. A.; Clinic of Cognitive Neurology University Medical Center Leipzig Leipzig Germany ; Department of Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany
Mantovani, Elisa; Department of Neurosciences Biomedicine and Movement Sciences University of Verona Verona Italy
Chandra, Avinash; Centre for Preventive Neurology Queen Mary University of London London UK
James, Sarah‐Naomi; Institute of Cardiovascular Science University College London London UK
Tang, Eugene Y. H.; Population Health Sciences Institute Newcastle University Newcastle upon Tyne UK
Llewellyn, David J.; Department of Health and Community Sciences University of Exeter Medical School, St Luke's Campus Exeter UK
Foote, Isabelle F.; Institute for Behavioral Genetics University of Colorado Boulder Colorado USA
Chiesa, Scott T.; Institute of Cardiovascular Science University College London London UK
GERAETS, Anouk ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > Department of Social Sciences (DSOC) > Socio-Economic Inequality
