Article (Scientific journals)
Detecting of a Patient's Condition From Clinical Narratives Using Natural Language Representation.
LE, Thanh-Dung; Noumeir, Rita; Rambaud, Jerome et al.
2022In IEEE open journal of engineering in medicine and biology, 3, p. 142 - 149
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Keywords :
Clinical natural language processing; cardiac failure; feature selection; imbalance learning; machine learning; Deep learning; Features selection; Language processing; Machine-learning; Medical diagnostic imaging; Natural languages; Performances evaluation; Representation learning; Biomedical Engineering; Computer Science - Computation and Language; eess.SP
Abstract :
[en] The rapid progress in clinical data management systems and artificial intelligence approaches enable the era of personalized medicine. Intensive care units (ICUs) are ideal clinical research environments for such development because they collect many clinical data and are highly computerized. Goal: We designed a retrospective clinical study on a prospective ICU database using clinical natural language to help in the early diagnosis of heart failure in critically ill children. Methods: The methodology consisted of empirical experiments of a learning algorithm to learn the hidden interpretation and presentation of the French clinical note data. This study included 1386 patients' clinical notes with 5444 single lines of notes. There were 1941 positive cases (36% of total) and 3503 negative cases classified by two independent physicians using a standardized approach. Results: The multilayer perceptron neural network outperforms other discriminative and generative classifiers. Consequently, the proposed framework yields an overall classification performance with 89% accuracy, 88% recall, and 89% precision. Conclusions: This study successfully applied learning representation and machine learning algorithms to detect heart failure in a single French institution from clinical natural language. Further work is needed to use the same methodology in other languages and institutions.
Disciplines :
Electrical & electronics engineering
Author, co-author :
LE, Thanh-Dung  ;  University of Luxembourg > Interdisciplinary Centre for Security, Reliability and Trust (SNT) > SigCom ; Biomedical Information Processing Lab, École de Technologie SupérieureUniversity of Québec Montreal QB H3G 1M8 Canada ; Research Center at CHU Sainte-Justine HospitalUniversity of Montreal Montreal QB H3T 1J4 Canada
Noumeir, Rita ;  Biomedical Information Processing Lab, École de Technologie SupérieureUniversity of Québec Montreal QB H3G 1M8 Canada
Rambaud, Jerome;  Research Center at CHU Sainte-Justine HospitalUniversity of Montreal Montreal QB H3T 1J4 Canada
Sans, Guillaume;  Research Center at CHU Sainte-Justine HospitalUniversity of Montreal Montreal QB H3T 1J4 Canada
Jouvet, Philippe ;  Research Center at CHU Sainte-Justine HospitalUniversity of Montreal Montreal QB H3T 1J4 Canada
External co-authors :
yes
Language :
English
Title :
Detecting of a Patient's Condition From Clinical Narratives Using Natural Language Representation.
Publication date :
2022
Journal title :
IEEE open journal of engineering in medicine and biology
eISSN :
2644-1276
Publisher :
Institute of Electrical and Electronics Engineers Inc., United States
Volume :
3
Pages :
142 - 149
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Accepted for publication in IEEE Open Journal of Engineering in Medicine and Biology. arXiv admin note: text overlap with arXiv:2104.03934
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