chronic pain; comorbidity; mental disorders; prevalence; quality of life; Clinical Psychology; Psychiatry and Mental Health
Abstract :
[en] Background: The high co-occurrence of chronic pain and mental disorders is well-established. Yet, an up-To-date account of the prevalence of mental disorders according to revised diagnostic criteria is lacking. Aims: The present study investigated the point and lifetime prevalence of a broad range of mental disorders according to DSM-5 in patients with chronic pain and examined associations of current mental health comorbidity with pain catastrophizing and health-related quality of life (HRQoL). Method: In this cross-sectional, observational study, patients with self-reported chronic pain receiving inpatient treatment at a specialized tertiary hospital were recruited for participation. Structured clinical interviews were conducted to assess current and lifetime diagnoses of mental disorders. Pain catastrophizing and HRQoL were assessed via questionnaires. Results: 145 patients (63.5% female; Mage = 54.9 years) participated in the study. 57.2% of the sample met the criteria for any current and 77.9% for any lifetime mental disorder. The most prevalent diagnostic groups of current mental disorders were substance-related and addictive disorders (26.2%), somatic symptom and related disorders (17.9%), depressive disorders (17.2%), and anxiety disorders (15.9%). Current mental health comorbidity was significantly associated with increased levels of pain catastrophizing and poorer HRQoL outcomes. Limitations: Chronic pain was only assessed by self-report, and no data regarding the exact medical diagnoses of the participants were collected. Conclusion: Comorbid mental disorders are highly prevalent in patients with chronic pain. Given the adverse effects of this comorbidity, the findings emphasize the need for addressing comorbid mental disorders in the management of chronic pain.
Disciplines :
Treatment & clinical psychology
Author, co-author :
THOMAS, Mirjam Verena ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences > Department of Behavioural and Cognitive Sciences > Team Claus VÖGELE
Van Ryckeghem, Dimitri M. L.; Department of Behavioural and Cognitive Sciences, University of Luxembourg, Esch-sur-Alzette, Luxembourg ; Department of Clinical Psychological Science, Maastricht University, Maastricht, Netherlands ; Department of Experimental Clinical and Health Psychology, Ghent University, Belgium
SCHULZ, André ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > Department of Behavioural and Cognitive Sciences (DBCS) > Health and Behaviour
MÜLLER, Ruta ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences > Department of Behavioural and Cognitive Sciences > Team André SCHULZ
Lambracht, Kai; Klinik für Manuelle Therapie Hamm, Germany
Adermann, Jens; Klinik für Manuelle Therapie Hamm, Germany
VÖGELE, Claus ; University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > Department of Behavioural and Cognitive Sciences (DBCS) > Health and Behaviour
External co-authors :
yes
Language :
English
Title :
Mental Disorders in Chronic Pain Patients Seeking Treatment at a Tertiary Pain Hospital A Cross-Sectional Study
This study was funded by the University of Luxembourg and the Klinik für Manuelle Therapie. The University of Luxembourg and the Klinik für Manuelle Therapie Hamm had no further role in the study design, in the collection, analysis, and interpretation of data, in the writing of the report, or in the decision to submit the paper for publication.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bibliography
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR. APA.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders. APA. https://doi.org/10.1176/appi.books.9780890425596
Annagür, B. B., Uguz, F., Apiliogullari, S., Kara, I., & Gunduz, S. (2014). Psychiatric disorders and association with quality of sleep and quality of life in patients with chronic pain: A SCID-based study. Pain Medicine, 15 (5), 772-781. https://doi.org/10.1111/pme.12390
Bair, M. J., Wu, J., Damush, T. M., Sutherland, J. M., & Kroenke, K. (2008). Association of depression and anxiety alone and in combination with chronic musculoskeletal pain in primary care patients. Psychosomatic Medicine, 70 (8), 890-897. https://doi.org/10.1097/PSY.0b013e318185c510
Baumeister, H., Knecht, A., & Hutter, N. (2012). Direct and indirect costs in persons with chronic back pain and comorbid mental disorders-A systematic review. Journal of Psychosomatic Research, 73 (2), 79-85. https://doi.org/10.1016/j.jpsychores.2012.05.008
Beesdo-Baum, K., Knappe, S., Asselmann, E., Zimmermann, P., Bruckl, T., Hofler, M., Behrendt, S., Lieb, R., & Wittchen, H. U. (2015). The "Early Developmental Stages of Psychopathology (EDSP) study": A 20-year review of methods and findings. Social Psychiatry and Psychiatric Epidemiology, 50 (6), 851-866. https://doi.org/10.1007/s00127-015-1062-x
Boersma, K., Sodermark, M., Hesser, H., Flink, I. K., Gerdle, B., & Linton, S. J. (2019). Efficacy of a transdiagnostic emotion-focused exposure treatment for chronic pain patients with comorbid anxiety and depression: A randomized controlled trial. Pain, 160 (8), 1708-1718. https://doi.org/10.1097/j.pain.0000000000001575
Borsbo, B., Peolsson, M., & Gerdle, B. (2009). The complex interplay between pain intensity, depression, anxiety and catastrophising with respect to quality of life and disability. Disability and Rehabilitation, 31 (19), 1605-1613. https://doi.org/10.1080/09638280903110079
Breivik, H., Collett, B., Ventafridda, V., Cohen, R., & Gallacher, D. (2006). Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. European Journal of Pain, 10 (4), 287-333. https://doi.org/10.1016/j.ejpain.2005.06.009
Brünahl, C., Dybowski, C., Albrecht, R., Riegel, B., Hoink, J., Fisch, M., & Lowe, B. (2017). Mental disorders in patients with chronic pelvic pain syndrome (CPPS). Journal of Psychosomatic Research, 98, 19-26. https://doi.org/10.1016/j.jpsychores.2017.04.011
Burke, A. L., Mathias, J. L., & Denson, L. A. (2015). Psychological functioning of people living with chronic pain: A meta-Analytic review. British Journal of Clinical Psychology, 54 (3), 345-360. https://doi.org/10.1111/bjc.12078
Cella, D., Choi, S. W., Condon, D. M., Schalet, B., Hays, R. D., Rothrock, N. E., Yount, S., Cook, K. F., Gershon, R. C., Amtmann, D., DeWalt, D. A., Pilkonis, P. A., Stone, A. A., Weinfurt, K., & Reeve, B. B. (2019). PROMIS®adult health profiles: Efficient short-form measures of seven health domains. Value in Health, 22 (5), 537-544. https://doi.org/10.1016/j.jval.2019.02.004
Cella, D., Riley, W., Stone, A., Rothrock, N., Reeve, B., Yount, S., Amtmann, D., Bode, R., Buysse, D., Choi, S., Cook, K., Devellis, R., DeWalt, D., Fries, J. F., Gershon, R., Hahn, E. A., Lai, J. S., Pilkonis, P., Revicki, D.,.. Group, P. C. (2010). The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008. Journal of Clinical Epidemiology, 63 (11), 1179-1194. https://doi.org/10.1016/j.jclinepi.2010.04.011
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Erlbaum.
Creed, F., & Gureje, O. (2012). Emerging themes in the revision of the classification of somatoform disorders. International Review of Psychiatry, 24 (6), 556-567. https://doi.org/10.3109/09540261.2012.741063
Crombez, G., Lauwerier, E., Lammertyn, A., Notebaert, L., Van Bockstaele, B., & Van Ryckeghem, D. (2012). Ghent Pain and Disability Study I (GPD-I)â »: Protocol. http://hdl.handle.net/1854/LU-3050986
Csupak, B., Sommer, J. L., Jacobsohn, E., & El-Gabalawy, R. (2018). A population-based examination of the co-occurrence and functional correlates of chronic pain and generalized anxiety disorder. Journal of Anxiety Disorders, 56, 74-80. https://doi.org/10.1016/j.janxdis.2018.04.005
Edwards, R. R., Dworkin, R. H., Sullivan, M. D., Turk, D. C., & Wasan, A. D. (2016). The role of psychosocial processes in the development and maintenance of chronic pain. Journal of Pain, 17 (9 Suppl), T70-92. https://doi.org/10.1016/j.jpain.2016.01.001
Edwards, R. R., Schreiber, K. L., Dworkin, R. H., Turk, D. C., Baron, R., Freeman, R., Jensen, T. S., Latremoliere, A., Markman, J. D., Rice, A. S. C., Rowbotham, M., Staud, R., Tate, S., Woolf, C. J., Andrews, N. A., Carr, D. B., Colloca, L., Cosma-Roman, D., Cowan, P.,.. Wesselmann, U. (2023). Optimizing and accelerating the development of precision pain treatments for chronic pain: IMMPACT review and recommendations. Journal of Pain, 24 (2), 204-225. https://doi.org/10.1016/j.jpain.2022.08.010
Ehret, A. M., & Berking, M. (2013). DSM-IV und DSM-5: Was hat sich tatsächlich verändert? [From DSM-IV to DSM-5: What has changed in the new edition?] Verhaltenstherapie, 23 (4), 258-266. https://doi.org/10.1159/000356537
Elashoff, J. D., & Lemeshow, S. (2014). Sample size determination in epidemiological studies. In W. Ahrens, & I. Pigeot (Eds.), Handbook of epidemiology (2nd ed., pp. 1023-1056). Springer. https://doi.org/10.1007/978-0-387-09834-0_15
Falkai, P., & Wittchen, H. U. (Eds.). (2018). Diagnostisches und Statistisches Manual Psychischer Störungen DSM-5® (Deutsche Ausgabe) [Diagnostic and statistical manual of mental disorders DSM-5, German edition]. Hogrefe. https://doi.org/10.1026/02803-000
Frances, A. (2013). The new somatic symptom disorder in DSM-5 risks mislabeling many people as mentally ill. British Medical Journal, 346, Article f1580. https://doi.org/10.1136/bmj.f1580
Gaskin, D. J., & Richard, P. (2012). The economic costs of pain in the United States. Journal of Pain, 13 (8), 715-724. https://doi.org/10.1016/j.jpain.2012.03.009
Goesling, J., Lin, L. A., & Clauw, D. J. (2018). Psychiatry and pain management: At the intersection of chronic pain and mental health. Current Psychiatry Reports, 20 (2), Article 12. https://doi.org/10.1007/s11920-018-0872-4
Goldberg, D. S., & McGee, S. J. (2011). Pain as a global public health priority. BMC Public Health, 11, Article 770. https://doi.org/10.1186/1471-2458-11-770
Gureje, O., Von Korff, M., Kola, L., Demyttenaere, K., He, Y., Posada-Villa, J., Lepine, J. P., Angermeyer, M. C., Levinson, D., de Girolamo, G., Iwata, N., Karam, A., Guimaraes Borges, G. L., de Graaf, R., Browne, M. O., Stein, D. J., Haro, J. M., Bromet, E. J., Kessler, R. C., & Alonso, J. (2008). The relation between multiple pains and mental disorders: Results from the World Mental Health Surveys. Pain, 135 (1-2), 82-91. https://doi.org/10.1016/j.pain.2007.05.005
Häuser, W., Bialas, P., Welsch, K., & Wolfe, F. (2015). Construct validity and clinical utility of current research criteria of DSM-5 somatic symptom disorder diagnosis in patients with fibromyalgia syndrome. Journal of Psychosomatic Research, 78 (6), 546-552. https://doi.org/10.1016/j.jpsychores.2015.03.151
Häuser, W., Hausteiner-Wiehle, C., Henningsen, P., Brahler, E., Schmalbach, B., & Wolfe, F. (2020). Prevalence and overlap of somatic symptom disorder, bodily distress syndrome and fibromyalgia syndrome in the German general population: A cross sectional study. Journal of Psychosomatic Research, 133, Article 110111. https://doi.org/10.1016/j.jpsychores.2020.110111
Hays, R. D., Spritzer, K. L., Schalet, B. D., & Cella, D. (2018). PROMIS®-29 v2.0 profile physical and mental health summary scores. Quality of Life Research, 27 (7), 1885-1891. https://doi.org/10.1007/s11136-018-1842-3
Ho, P. T., Li, C. F., Ng, Y. K., Tsui, S. L., & Ng, K. F. (2011). Prevalence of and factors associated with psychiatric morbidity in chronic pain patients. Journal of Psychosomatic Research, 70 (6), 541-547. https://doi.org/10.1016/j.jpsychores.2010.10.006
Hysing, E. B., Smith, L., Thulin, M., Karlsten, R., Butler, S., & Gordh, T. (2017). Identifying characteristics of the most severely impaired chronic pain patients treated at a specialized inpatient pain clinic. Scandinavian Journal of Pain, 17, 178-185. https://doi.org/10.1016/j.sjpain.2017.09.008
Kaiser, U., Treede, R. D., & Sabatowski, R. (2017). Multimodal pain therapy in chronic noncancer pain-gold standard or need for further clarification? Pain, 158 (10), 1853-1859. https://doi.org/10.1097/j.pain.0000000000000902
Kang, Y., Trewern, L., Jackman, J., McCartney, D., & Soni, A. (2023). Chronic pain: Definitions and diagnosis. British Medical Journal, 381, Article e076036. https://doi.org/10.1136/bmj-2023-076036
Katz, N. (2002). The impact of pain management on quality of life. Journal of Pain and Symptom Management, 24 (1), S38-S47. https://doi.org/10.1016/s0885-3924(02)00411-6
Knaster, P., Karlsson, H., Estlander, A. M., & Kalso, E. (2012). Psychiatric disorders as assessed with SCID in chronic pain patients: The anxiety disorders precede the onset of pain. General Hospital Psychiatry, 34 (1), 46-52. https://doi.org/10.1016/j.genhosppsych.2011.09.004
Lame, I. E., Peters, M. L., Vlaeyen, J. W., Kleef, M., & Patijn, J. (2005). Quality of life in chronic pain is more associated with beliefs about pain, than with pain intensity. European Journal of Pain, 9 (1), 15-24. https://doi.org/10.1016/j.ejpain.2004.02.006
Landis, J. R., & Koch, G. G. (1977). The measurement of observer agreement for categorical data. Biometrics, 33 (1), 159-174. https://www.ncbi.nlm.nih.gov/pubmed/843571
Margraf, J., Cwik, J. C., Pflug, V., & Schneider, S. (2017). Strukturierte klinische Interviews zur Erfassung psychischer Störungen über die Lebensspanne [Structured clinical interviews for mental disorders across the life span: psychometric quality and further developments of the DIPS open access interviews]. Zeitschrift für Klinische Psychologie und Psychotherapie, 46 (3), 176-186. https://doi.org/10.1026/1616-3443/a000430
Margraf, J., Cwik, J. C., Suppiger, A., & Schneider, S. (2017). DIPS Open Access: Diagnostisches Interview bei psychischen Störungen [DIPS Open Access: Diagnostic interview for mental disorders]. Mental Health Research and Treament Center, Ruhr-Universität Bochum. https://doi.org/10.13154/rub.100.89
Mayou, R., Kirmayer, L. J., Simon, G., Kroenke, K., & Sharpe, M. (2005). Somatoform disorders: Time for a new approach in DSM-V. American Journal of Psychiatry, 162 (5), 847-855. https://doi.org/10.1176/appi.ajp.162.5.847
Meyer, K., Sprott, H., & Mannion, A. F. (2008). Cross-cultural adaptation, reliability, and validity of the German version of the Pain Catastrophizing Scale. Journal of Psychosomatic Research, 64 (5), 469-478. https://doi.org/10.1016/j.jpsychores.2007.12.004
Moffitt, T. E., Caspi, A., Taylor, A., Kokaua, J., Milne, B. J., Polanczyk, G., & Poulton, R. (2010). How common are common mental disorders? Evidence that lifetime prevalence rates are doubled by prospective versus retrospective ascertainment. Psychological Medicine, 40 (6), 899-909. https://doi.org/10.1017/S0033291709991036
Nafziger, A. N., & Barkin, R. L. (2018). Opioid therapy in acute and chronic pain. Journal of Clinical Pharmacology, 58 (9), 1111-1122. https://doi.org/10.1002/jcph.1276
Onwumere, J., Stubbs, B., Stirling, M., Shiers, D., Gaughran, F., Rice, A. S. C., Williams, A. C. D. C., & Scott, W. (2022). Pain management in people with severe mental illness: An agenda for progress. Pain, 163 (9), 1653-1660. https://doi.org/10.1097/j.pain.0000000000002633
Park, S. J., Lee, R., Yoon, D. M., Yoon, K. B., Kim, K., & Kim, S. H. (2016). Factors associated with increased risk for pain catastrophizing in patients with chronic neck pain: A retrospective cross-sectional study. Medicine (Baltimore), 95 (37), Article e4698. https://doi.org/10.1097/MD.0000000000004698
Plana-Ripoll, O., Pedersen, C. B., Holtz, Y., Benros, M. E., Dalsgaard, S., de Jonge, P., Fan, C. C., Degenhardt, L., Ganna, A., Greve, A. N., Gunn, J., Iburg, K. M., Kessing, L. V., Lee, B. K., Lim, C. C. W., Mors, O., Nordentoft, M., Prior, A., Roest, A. M.,.. McGrath, J. J. (2019). Exploring comorbidity within mental disorders among a Danish national population. JAMA Psychiatry, 76 (3), 259-270. https://doi.org/10.1001/jamapsychiatry.2018.3658
Schaeuffele, C., Schulz, A., Knaevelsrud, C., Renneberg, B., & Boettcher, J. (2020). CBT at the crossroads: The rise of transdiagnostic treatments. International Journal of Cognitive Therapy, 14 (1), 86-113. https://doi.org/10.1007/s41811-020-00095-2
Schrepf, A., Williams, D. A., Gallop, R., Naliboff, B. D., Basu, N., Kaplan, C., Harper, D. E., Richard Landis, J., Quentin Clemens, J., Strachan, E., Griffith, J. W., Afari, N., Hassett, A., Pontari, M. A., Clauw, D. J., & Harte, S. E. (2018). Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: A MAPP Research Network study. Pain, 159 (10), 2002-2011. https://doi.org/10.1097/j.pain.0000000000001299
Sleurs, D., Tebeka, S., Scognamiglio, C., Dubertret, C., & Le Strat, Y. (2020). Comorbidities of self-reported fibromyalgia in United States adults: A cross-sectional study from The National Epidemiological Survey on Alcohol and Related Conditions (NESARC-III). European Journal of Pain, 24 (8), 1471-1483. https://doi.org/10.1002/ejp.1585
Sondergard, S., Vaegter, H. B., Erlangsen, A., & Stenager, E. (2018). Ten-year prevalence of mental disorders in patients presenting with chronic pain in secondary care: A register linkage cohort study. European Journal of Pain, 22 (2), 346-354. https://doi.org/10.1002/ejp.1124
Steel, Z., Marnane, C., Iranpour, C., Chey, T., Jackson, J. W., Patel, V., & Silove, D. (2014). The global prevalence of common mental disorders: A systematic review and meta-Analysis 1980-2013. International Journal of Epidemiology, 43 (2), 476-493. https://doi.org/10.1093/ije/dyu038
Taylor, S. J. C., Carnes, D., Homer, K., Pincus, T., Kahan, B. C., Hounsome, N., Eldridge, S., Spencer, A., Diaz-Ordaz, K., Rahman, A., Mars, T. S., Foell, J., Griffiths, C. J., & Underwood, M. R. (2016). Improving the self-management of chronic pain: COping with persistent Pain, Effectiveness Research in Self-management (COPERS). Programme Grants for Applied Research, 4 (14), 85-101. https://doi.org/10.3310/pgfar04140
Treede, R. D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Korwisi, B., Kosek, E., Lavand'homme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S.,.. Wang, S. J. (2019). Chronic pain as a symptom or a disease: The IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain, 160 (1), 19-27. https://doi.org/10.1097/j.pain.0000000000001384
Uher, R., Payne, J. L., Pavlova, B., & Perlis, R. H. (2014). Major depressive disorder in DSM-5: Implications for clinical practice and research of changes from DSM-IV. Depression and Anxiety, 31 (6), 459-471. https://doi.org/10.1002/da.22217
Vartiainen, P., Heiskanen, T., Sintonen, H., Roine, R. P., & Kalso, E. (2016). Health-related quality of life and burden of disease in chronic pain measured with the 15D instrument. Pain, 157 (10), 2269-2276. https://doi.org/10.1097/j.pain.0000000000000641
Yong, R. J., Mullins, P. M., & Bhattacharyya, N. (2022). Prevalence of chronic pain among adults in the United States. pain, 163 (2), e328-e332. https://doi.org/10.1097/j.pain.0000000000002291
Similar publications
Sorry the service is unavailable at the moment. Please try again later.
