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Neuropeptides and inflammation: presumed mechanisms in neurogenic inflammation
Landry, Y.; Bloch, J. G.; Mousli, M. et al.
1990In Pathologie et Biologie, 38 (1), p. 53-6
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Keywords :
Arthritis; Humans; Inflammation; Mast Cells; Membrane Proteins; Neuropeptides; Substance P; physiopathology; physiology
Abstract :
[en] Neuropeptides, among which substance P, VIP (Vasoactive intestinal peptide), somatostatin, neurotensin, dynorphin and enkephalins, are able to modulate inflammatory processes. Increasing interest is now devoted to these peptides in different inflammatory diseases, concerning skin, lung and joins. The effect of substance P can be dependent on its C-terminal moiety implicating by this way an interaction with specific neurokinin receptors or can be dependent on its N-terminal moiety which does not involve a specific membrane receptor. Such diversity of the action mechanisms of peptides should influence the evolution of the anti-inflammatory therapeutic.
Disciplines :
Biochemistry, biophysics & molecular biology
Identifiers :
UNILU:UL-ARTICLE-2008-208
Author, co-author :
Landry, Y.
Bloch, J. G.
Mousli, M.
Bueb, Jean-Luc ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit
Bronner, C.
Language :
English
Title :
Neuropeptides and inflammation: presumed mechanisms in neurogenic inflammation
Publication date :
1990
Journal title :
Pathologie et Biologie
ISSN :
0369-8114
eISSN :
1768-3114
Publisher :
Elsevier, Paris, France
Volume :
38
Issue :
1
Pages :
53-6
Peer reviewed :
Peer reviewed
Available on ORBilu :
since 09 September 2013

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