Eprint already available on another site (E-prints, Working papers and Research blog)
Integration of external biomass reactions into existing metabolic models
Moscardo Garcia, Maria; Pires Pacheco, Maria Irene; Sauter, Thomas
2022
 

Files


Full Text
2022.08.01.502323v1.full.pdf
Publisher postprint (972.24 kB)
Download

All documents in ORBilu are protected by a user license.

Send to



Details



Abstract :
[en] Currently, seven biomass objective functions have been defined in human metabolic reconstructions. The integration of published biomass reactions into alternative models can contribute to the prediction power of the model. Thus, in this work, we present a workflow to integrate reactions and biomass functions originating from several genome-scale reconstructions into models other than their home models. Additionally, a benchmark to identify the biomass that confers the highest prediction accuracy in terms of gene essentiality and growth predictions is provided.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Moscardo Garcia, Maria ;  University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)
Pires Pacheco, Maria Irene ;  University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)
Sauter, Thomas ;  University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)
Language :
English
Title :
Integration of external biomass reactions into existing metabolic models
Publication date :
03 August 2022
Publisher :
Cold Spring Harbor Laboratory Press
Available on ORBilu :
since 24 September 2022

Statistics


Number of views
84 (2 by Unilu)
Number of downloads
64 (3 by Unilu)

Bibliography


Similar publications



Contact ORBilu