Reference : The ecology of the unseen
Scientific journals : Article
Life sciences : Microbiology
http://hdl.handle.net/10993/50440
The ecology of the unseen
English
Wilmes, Paul mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology >]
Feb-2022
Archives des Sciences Naturelles, Physiques et Mathématiques
Institut Grand-Ducal de Lxuembourg
XLVIII
45-50
Yes
International
Luxembourg
Luxembourg
[en] Antibiotics ; biomolecules ; diet ; disease ; gut ; health ; microbial ecology ; microbiome
[en] On the global scale, humankind is having a profound impact on the ecology of assemblages
of organisms which we can see with the naked eye. At the same time, we are also starting
to learn about the impact of our collective, modern lifestyles on the ecology of the unseen, for
example the microbes in our gut which are being affected by the overuse of antibiotics and unhealthy
diets. However, we do not fully understand which functions the microorganisms fulfill as
our knowledge so far is rather limited. In our own research, we see for example that 50-90 % of
the molecules produced by microbes are completely unknown to Science but likely play important
roles in key physiological processes. This means that we as humans are presently affecting
key microbial processes in our bodies without fully understanding the possible repercussions.
In addition, many of these molecules likely have bioactive properties and, thereby, represent
an untapped resource for the development of new drugs. Therefore, it is important that we start
charting out this great molecular expanse to ensure its stewardship for generations to come.
European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No. 863664)
Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease
http://hdl.handle.net/10993/50440
H2020 ; 863664 - ExpoBiome - Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease

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