Article (Scientific journals)
ELIXIR and Toxicology: a community in development
Martens, Marvin; Stierum, Rob; Schymanski, Emma et al.
2021In F1000Research, 10, p. 1129
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Abstract :
[en] Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Martens, Marvin
Stierum, Rob
Schymanski, Emma  ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Evelo, Chris T.
Aalizadeh, Reza
Aladjov, Hristo
Arturi, Kasia
Audouze, Karine
Babica, Pavel
Berka, Karel
Bessems, Jos
Blaha, Ludek
Bolton, Evan E.
Cases, Montserrat
Damalas, Dimitrios Ε.
Dave, Kirtan
Dilger, Marco
Exner, Thomas
Geerke, Daan P.
Grafström, Roland
Gray, Alasdair
Hancock, John M.
Hollert, Henner
Jeliazkova, Nina
Jennen, Danyel
Jourdan, Fabien
Kahlem, Pascal
Klanova, Jana
Kleinjans, Jos
Kondic, Todor ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Environmental Cheminformatics
Kone, Boï
Lynch, Iseult
Maran, Uko
Martinez Cuesta, Sergio
Ménager, Hervé
Neumann, Steffen
Nymark, Penny
Oberacher, Herbert
Ramirez, Noelia
Remy, Sylvie
Rocca-Serra, Philippe
Salek, Reza M.
Sallach, Brett
Sansone, Susanna-Assunta
Sanz, Ferran
Sarimveis, Haralambos
Sarntivijai, Sirarat
Schulze, Tobias
Slobodnik, Jaroslav
Spjuth, Ola
Tedds, Jonathan
Thomaidis, Nikolaos
Weber, Ralf J. M.
van Westen, Gerard J. P.
Wheelock, Craig E.
Williams, Antony J.
Witters, Hilda
Zdrazil, Barbara
Županič, Anže
Willighagen, Egon L.
More authors (50 more) Less
External co-authors :
yes
Language :
English
Title :
ELIXIR and Toxicology: a community in development
Publication date :
2021
Journal title :
F1000Research
ISSN :
2046-1402
Publisher :
F1000 Research Ltd, London, United Kingdom
Volume :
10
Pages :
1129
Peer reviewed :
Peer Reviewed verified by ORBi
Focus Area :
Systems Biomedicine
FnR Project :
FNR12341006 - Environmental Cheminformatics To Identify Unknown Chemicals And Their Effects, 2018 (01/10/2018-30/09/2023) - Emma Schymanski
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since 10 January 2022

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