[en] The nonequilibrium activity taking place in a living cell can be monitored with a tracer embedded in the medium. While microrheology experiments based on optical manipulation of such probes have become increasingly standard, we put forward a number of experiments with alternative protocols that, we claim, will provide insight into the energetics of active fluctuations. These are based on either performing thermodynamiclike cycles in control-parameter space or determining response to external perturbations of the confining trap beyond simple translation. We illustrate our proposals on an active itinerant Brownian oscillator modeling the dynamics of a probe embedded in a living medium.
Disciplines :
Physics
Author, co-author :
Fodor, Etienne ; University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Physics and Materials Science (DPHYMS)
Kanazawa, K.; Yukawa Institute for Theoretical Physics, Kyoto University, Kitashirakawa-oiwake cho, Sakyo-ku, Kyoto 606-8502, Japan
Hayakawa, H.; Yukawa Institute for Theoretical Physics, Kyoto University, Kitashirakawa-oiwake cho, Sakyo-ku, Kyoto 606-8502, Japan
Visco, P.; Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS/P7, Université Paris Diderot, 10 rue Alice Domon et Léonie Duquet, 75205 Paris cedex 13, France
van Wijland, F.; Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS/P7, Université Paris Diderot, 10 rue Alice Domon et Léonie Duquet, 75205 Paris cedex 13, France
External co-authors :
yes
Language :
English
Title :
Energetics of active fluctuations in living cells
Publication date :
2014
Journal title :
Physical Review. E.
ISSN :
1539-3755
Publisher :
AMER PHYSICAL SOC, ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA, Unknown/unspecified
