Article (Scientific journals)
Does lobar or size-reduced lung transplantation offer satisfactory early and late outcomes?
Silva, João Santos; Olland, Anne; Massard, Gilbert et al.
2020In Interactive Cardiovascular and Thoracic Surgery
Peer Reviewed verified by ORBi
 

Files


Full Text
Silva et al., 2020.pdf
Publisher postprint (145.35 kB)
Request a copy

All documents in ORBilu are protected by a user license.

Send to



Details



Keywords :
Donor pool; Size reduced; Lung transplantation
Abstract :
[en] A best evidence topic was constructed according to a structured protocol. The question addressed was whether size-reduced or lobar lung transplantation (LLTx) offers the same benefit as classic lung transplantation (LTx). Of the 147 papers found using the reported search, 9 were selected to provide the best evidence. Details of the studies regarding authors, date, journal, country of publication, study type, group studied, relevant outcomes and results are given. All studies reported survival rates of LLTx and most compared it with classical LTx. No statistical differences were reported in medium term and long term. Two of the studies reported a higher incidence of postoperative complications, such as the need for cardiopulmonary bypass, reperfusion oedema or primary graft dysfunction, and longer intubation or intensive care unit stay times. Although the largest study showed a significantly worse 1-year survival in LLTx, a sub-analysis considering patients successfully discharged showed similar outcomes at 1, 3 and 5 years when compared with classic LTx patients. We conclude that LLTx is a valid therapeutic option for recipients with significant donor size mismatch, offering similar outcomes as classical LTx in the medium term and long term.
Disciplines :
Surgery
Author, co-author :
Silva, João Santos;  Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France > Service de Chirurgie Thoracique
Olland, Anne;  Hôpitaux Universitaires de Strasbourg, Strasbourg, France > Service de Chirurgie Thoracique, Nouvel Hôpital Civil ; INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, France
Massard, Gilbert ;  University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM) ; Hôpitaux Universitaires de Strasbourg, Strasbourg, France > Service de Chirurgie Thoracique, Nouvel Hôpital Civil
Falcoz, Pierre-Emmanuel;  Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France > Service de Chirurgie Thoracique ; INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, France
External co-authors :
yes
Language :
English
Title :
Does lobar or size-reduced lung transplantation offer satisfactory early and late outcomes?
Publication date :
24 April 2020
Journal title :
Interactive Cardiovascular and Thoracic Surgery
ISSN :
1569-9285
Publisher :
Elsevier, Netherlands
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 22 January 2021

Statistics


Number of views
117 (2 by Unilu)
Number of downloads
0 (0 by Unilu)

Scopus citations®
 
4
Scopus citations®
without self-citations
3
OpenCitations
 
2
WoS citations
 
3

Bibliography


Similar publications



Contact ORBilu