Article (Scientific journals)
In Lung Transplantation, Are Pulmonary Grafts From Donors Deceased From Hanging as Suitable as Grafts From Donors Deceased From Other Causes?
Santos Silva, João; Olland, Anne; Massard, Gilbert et al.
2019In Interactive Cardiovascular and Thoracic Surgery
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Keywords :
Donor pool; Hanging donors; Lung transplantation; Outcomes; Thoracic surgery
Abstract :
[en] A best evidence topic was constructed according to a structured protocol. The question addressed was whether pulmonary grafts from donors deceased from hanging offer the same benefit as grafts from donors deceased from other causes in lung transplantation. Of the 17papers found, 4 provided the best evidence to answer the question. The authors, date, journal, country of publication, study type, group studied, relevant outcomes and results of these papers are tabulated. One study reported a large cohort of donors and analysed the out-comes by cause of death, reporting no differences in survival. The remaining 3 papers analysed observational studies on the outcomes of lung transplantation using pulmonary grafts from donors deceased from hanging, compared with donors deceased from other causes. No differences in the rates of post-transplantation pulmonary graft dysfunction and long-term overall survival were reported. Although the cohort of donors deceased from hanging is small, we conclude that these donors are an important contribution to the donor pool. Ex vivo lung perfusion may have a role in assessing graft viability in this scenario
Disciplines :
Surgery
Author, co-author :
Santos Silva, João;  Hôpitaux Universitaire de Strasbourg, France > Service de Chirurgie Thoracique
Olland, Anne;  Hôpitaux Universitaire de Strasbourg, France. > Service de Chirurgie Thoracique ; INSERM (French National Institute of Health and Medical Research) > Regenerative Nanomedicine (RNM) ; Université de Strasbourg, France > Faculté de Médecine et Pharmacie
Massard, Gilbert ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) ; Hôpitaux Universitaire de Strasbourg, France > Service de Chirurgie Thoracique ; INSERM (French National Institute of Health and Medical Research) > Regenerative Nanomedicine ; Université de Strasbourg > Faculté de Médecine et Pharmacie
Falcoz, Pierre-Emmanuel;  Hôpitaux Universitaire de Strasbourg, France > Service de Chirurgie Thoracique ; INSERM (French National Institute of Health and Medical Research) > Regenerative Nanomedicine (RNM) ; Université de Strasbourg, France > Faculté de Médecine et Pharmacie
External co-authors :
yes
Language :
English
Title :
In Lung Transplantation, Are Pulmonary Grafts From Donors Deceased From Hanging as Suitable as Grafts From Donors Deceased From Other Causes?
Publication date :
2019
Journal title :
Interactive Cardiovascular and Thoracic Surgery
ISSN :
1569-9285
Publisher :
Elsevier, Netherlands
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 03 March 2020

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