Article (Scientific journals)
Plasmonic nanopores for single-molecule detection and manipulation: towards sequencing applications
Garoli, Denis; Yamazaki, Hirohito; Maccaferri, Nicolò et al.
2019In Nano Letters, 19 (11), p. 7553-7562
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Keywords :
Plasmonics; Nanopore; Solid-state; Sequencing; Single-molecule
Abstract :
[en] Solid-state nanopore-based sensors are promising platforms for next-generation sequencing technologies, featuring label-free single-molecule sensitivity, rapid detection, and low-cost manufacturing. In recent years, solid-state nanopores have been explored due to their miscellaneous fabrication methods and their use in a wide range of sensing applications. Here, we highlight a novel family of solid-state nanopores which have recently appeared, namely plasmonic nanopores. The use of plasmonic nanopores to engineer electromagnetic fields around a nanopore sensor allows for enhanced optical spectroscopies, local control over temperature, thermophoresis of molecules and ions to/from the sensor, and trapping of entities. This Mini Review offers a comprehensive understanding of the current state-of-the-art plasmonic nanopores for single-molecule detection and biomolecular sequencing applications and discusses the latest advances and future perspectives on plasmonic nanopore-based technologies.
Disciplines :
Physics
Author, co-author :
Garoli, Denis;  Istituto Italiano di Tecnologia
Yamazaki, Hirohito;  Northeastern University
Maccaferri, Nicolò ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Physics and Materials Science Research Unit
Wanunu, Meni;  Northeastern University
External co-authors :
yes
Language :
English
Title :
Plasmonic nanopores for single-molecule detection and manipulation: towards sequencing applications
Publication date :
2019
Journal title :
Nano Letters
ISSN :
1530-6992
Publisher :
American Chemical Society, Washington, United States - District of Columbia
Volume :
19
Issue :
11
Pages :
7553-7562
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 08 October 2019

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