Reference : Plasmonic zero mode waveguide for highly confined and enhanced fluorescence emission
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Physics
Plasmonic zero mode waveguide for highly confined and enhanced fluorescence emission
Ponzellini, Paolo [> >]
Zambrana-Puyalto, Xavier [> >]
Maccaferri, Nicolò mailto [Istituto Italiano di Tecnologia]
Lanzano, Luca [> >]
De Angelis, Francesco [> >]
Garoli, Denis [> >]
Yes (verified by ORBilu)
[en] We fabricate a plasmonic nanoslot that is capable of performing enhanced single molecule detection at 10 muM concentrations. The nanoslot combines the tiny detection volume of a zero-mode waveguide and the field enhancement of a plasmonic nanohole. The nanoslot is fabricated on a bi-metallic film formed by the sequential deposition of gold and aluminum on a transparent substrate. Simulations of the structure yield an average near-field intensity enhancement of two orders of magnitude at its resonant frequency. Experimentally, we measure the fluorescence stemming from the nanoslot and compare it with that of a standard aluminum zero-mode waveguide. We also compare the detection volume for both structures. We observe that while both structures have a similar detection volume, the nanoslot yields a 25-fold fluorescence enhancement.
H2020 ; 687089 - PROSEQO - PROtein SEQuencing using Optical single molecule real-time detection

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