[en] The application of constraint-based modeling to functionally analyze metagenomic data has been limited so far, partially due to the absence of suitable toolboxes.
To address this gap, we created a comprehensive toolbox to model i) microbe-microbe and host-microbe metabolic interactions, and ii) microbial communities using microbial genome-scale metabolic reconstructions and metagenomic data. The Microbiome Modeling Toolbox extends the functionality of the COBRA Toolbox.
The Microbiome Modeling Toolbox and the tutorials at https://git.io/microbiomeModelingToolbox.
Disciplines :
Microbiologie Sciences du vivant: Multidisciplinaire, généralités & autres
Auteur, co-auteur :
BALDINI, Federico ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
HEINKEN, Almut Katrin ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
HEIRENDT, Laurent ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Magnusdottir, Stefania
Fleming, Ronan; Leiden Academic Centre for Drug Research > LACDR/Analytical Biosciences
THIELE, Ines ; University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Co-auteurs externes :
yes
Langue du document :
Anglais
Titre :
The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities
Date de publication/diffusion :
21 novembre 2018
Titre du périodique :
Bioinformatics
ISSN :
1367-4803
eISSN :
1367-4811
Maison d'édition :
Oxford University Press, Oxford, Royaume-Uni
Titre particulier du numéro :
The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities
