Article (Scientific journals)
Modeling metabolism of the human gut microbiome
Magnusdottir, Stefania; Thiele, Ines
2018In Current Opinion in Biotechnology
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Abstract :
[en] The human gut microbiome plays an important part in human health. The complexity of the microbiome makes it difficult to determine the detailed metabolic functions and cross-talk occurs between the individual species. In silico systems biology studies of the microbiome can help to identify metabolite exchanges among gut microbes. Constraint-based reconstruction and analysis methods use biochemically accurate genome-scale metabolic networks of microorganisms to simulate metabolism between species in a given microbiome and help generate novel hypotheses on microbial interactions. Here, we review metabolic modeling studies that have investigated metabolic functions of the gut microbiome.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Magnusdottir, Stefania ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
Thiele, Ines ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB)
External co-authors :
yes
Language :
English
Title :
Modeling metabolism of the human gut microbiome
Publication date :
2018
Journal title :
Current Opinion in Biotechnology
ISSN :
0958-1669
Publisher :
Elsevier Science
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 11 May 2018

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