[en] During working days, home and workplace are anchor locations shaping the daily mobility as well as the employee’s activity pattern. While past research has shown that workplace decentralization is often associated with higher car use for the commuting trip, little is known concerning the effect on activity-travel patterns as whole. The objective of this paper is to assess how workplace decentralization is affecting individuals’ daily activity space. A two-weeks travel diary has been filled by 43 employees of the University of Luxembourg, both before and after the relocation of their workplace. Using descriptive statistics, as well as Standard Deviational Ellipses (SDE) combined with a cluster analysis, results of this paper show that workers’ activity spaces, represented by the Standard Deviational Ellipses, have been importantly modified due to a relocation of a single anchor activity location, i.e. their workplace