TopoGSA: network topological gene set analysis

Reference : TopoGSA: network topological gene set analysis


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/10993/3312

Title :	TopoGSA: network topological gene set analysis
Language :	English
Author, co-author :	Glaab, Enrico [School of Computer Science, University of Nottingham, Nottingham, UK]
	Baudot, Anais [Structural Biology and Biocomputing Program, CNIO, Madrid, Spain]
	Krasnogor, Natalio [School of Computer Science, University of Nottingham, Nottingham, UK]
	Valencia, Alfonso [Structural Biology and Biocomputing Program, CNIO, Madrid, Spain]
Publication date :	2010
Journal title :	Bioinformatics
Publisher :	Oxford University Press - Journals Department
Volume :	26
Issue/season :	9
Pages :	1271-1272
Peer reviewed :	Yes (verified by ORBi^lu)
ISSN :	1367-4803
e-ISSN :	1460-2059
City :	Oxford
Country :	United Kingdom
Abstract :	[en] TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes.
Permalink :	http://hdl.handle.net/10993/3312
DOI :	10.1093/bioinformatics/btq131

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