[en] TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes.
Disciplines :
Biochemistry, biophysics & molecular biology
Identifiers :
UNILU:UL-ARTICLE-2011-375
Author, co-author :
Glaab, Enrico ; School of Computer Science, University of Nottingham, Nottingham, UK
Baudot, Anais; Structural Biology and Biocomputing Program, CNIO, Madrid, Spain
Krasnogor, Natalio; School of Computer Science, University of Nottingham, Nottingham, UK
Valencia, Alfonso; Structural Biology and Biocomputing Program, CNIO, Madrid, Spain
External co-authors :
yes
Language :
English
Title :
TopoGSA: network topological gene set analysis
Publication date :
2010
Journal title :
Bioinformatics
ISSN :
1367-4803
eISSN :
1460-2059
Publisher :
Oxford University Press - Journals Department, Oxford, United Kingdom