Article (Scientific journals)
Late outcomes of drug eluting and bare metal stents in saphenous vein graft percutaneous coronary intervention.
Nair, Satheesh; Fath-Ordoubadi, Farzin; Clarke, Bernard et al.
2011In EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 6 (8), p. 985-91
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Keywords :
Aged; Angioplasty, Balloon, Coronary/mortality; Cohort Studies; Coronary Artery Disease/mortality/therapy; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Metals; Middle Aged; Retreatment/statistics & numerical data; Retrospective Studies; Risk Factors; Saphenous Vein/transplantation; Treatment Outcome
Abstract :
[en] AIMS: PCI with drug eluting stents (DES) has been shown to reduce restenosis and major adverse cardiac event (MACE) rates compared to bare metal stents (BMS) in native coronary vessels, although outcomes in saphenous vein graft (SVG) lesions are less clear. We retrospectively studied 388 consecutive patients admitted to our centre for SVG PCI to assess mortality and MACE outcomes (defined as composite endpoint of all-death, stroke, myocardial infarction, stent thrombosis and target lesion (TLR)/vessel (TVR) revascularisation) associated with BMS and DES use. METHODS AND RESULTS: Two hundred and nineteen (219) patients had BMS and 169 had DES (total 388 patients). Mean follow up was 41.9+/-23.5 months. No significant differences were observed in mortality (14.2% vs. 11.8%) or MACE (37.6% vs. 35.8%) between the BMS and DES groups at four years follow-up or at other intervening time points studied. Similarly, no differences in TVR/TLR rates were observed over a similar time period (19.8% vs. 21.6%). CONCLUSIONS: We have observed that DES and BMS use in SVG PCI have comparable mortality and MACE rates, and that in contrast to PCI in native coronary arteries, DES do not reduce revascularisation rates in our study cohort.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Nair, Satheesh
Fath-Ordoubadi, Farzin
Clarke, Bernard
El-Omar, Magdi
Foley, James
Fraser, Doug G.
Mahadevan, Vaikom S.
Neyses, Ludwig ;  University of Luxembourg > Research Office
Khattar, Raj S.
Mamas, Mamas A.
External co-authors :
yes
Language :
English
Title :
Late outcomes of drug eluting and bare metal stents in saphenous vein graft percutaneous coronary intervention.
Publication date :
2011
Journal title :
EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
ISSN :
1969-6213
Publisher :
Société Europa Edition, Toulouse, France
Volume :
6
Issue :
8
Pages :
985-91
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBilu :
since 04 July 2016

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