Reference : [Diagnostic and prognostic value of plasma ANP determination after myocardial infarction].
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
[Diagnostic and prognostic value of plasma ANP determination after myocardial infarction].
[en] Diagnostische und prognostische Bedeutung der Plasma-ANP-Messung nach Myokardinfarkt.
Neyses, Ludwig mailto [University of Luxembourg > Research Office]
Biegel, H. [> >]
Heinrichs, S. [> >]
Nitsch, J. [> >]
Luderitz, B. [> >]
Zeitschrift fur Kardiologie
77 Suppl 2
Yes (verified by ORBilu)
[en] Angiocardiography ; Atrial Natriuretic Factor/blood ; Blood Pressure ; Humans ; Hypertension/blood ; Middle Aged ; Myocardial Infarction/blood/diagnosis ; Prognosis ; Reference Values
[en] In the present study the prognostic value of ANP measurement was investigated in 52 patients undergoing coronary angiography. 22 normotensive and 30 hypertensive subjects were included. A significant inverse correlation between left ventricular ejection fraction (EF) and plasma ANP was found in normotensives, but not in hypertensives. In patients with chronic myocardial infarction, there was no difference in ANP levels compared to patients without infarction in either group, provided that EF was normal. However, hypertensives showed a 35% increase in ANP compared to normotensives. This was true for subjects with and without myocardial infarction. These results show that in normotensives ANP levels have a prognostic value on a statistical rather than an individual basis. This does not apply to hypertensives, whose ANP level is increased by factors other than impaired ejection fraction.

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