No document available.
Keywords :
Adipose Tissue, Brown/metabolism; Animals; Insulin Resistance/genetics; Ion Channels/metabolism; Mitochondrial Proteins/metabolism; Non-alcoholic Fatty Liver Disease/genetics; Obesity/genetics; Serotonin/biosynthesis; Thermogenesis/genetics; Tryptophan Hydroxylase/genetics
Abstract :
[en] Serotonin acts as neurotransmitter in the brain and as a multifaceted signaling molecule coordinating many physiological processes in the periphery. In a recent issue of Nature Medicine, Crane et al. (2014) find that peripheral serotonin controls thermogenesis in adipose tissue by modulating beta-adrenergic stimulation of UCP-1, thereby affecting glucose homeostasis and weight gain.
Scopus citations®
without self-citations
4