Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Zi, Min; Kimura, Tomomi E.; Liu, Wei; Jin, Jiawei; Higham, Jonathan; Kharche, Sanjay; Hao, Guoliang; Shi, Ying; Shen, Weijian; Prehar, Sukhpal; Mironov, Aleksandr; Neyses, Ludwig; Bierhuizen, Marti F. A.; Boyett, Mark R.; Zhang, Henggui; Lei, Ming; Cartwright, Elizabeth J.; Wang, Xin

doi:10.1074/jbc.M111.228791

Article (Scientific journals)

Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Zi, Min; Kimura, Tomomi E.; Liu, Wei et al.

2011 • In The Journal of biological chemistry, 286 (20), p. 17821-30

Peer reviewed

Permalink
https://hdl.handle.net/10993/18375

DOI
10.1074/jbc.M111.228791

PubMed
21454599

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Keywords :

Animals; Arrhythmogenic Right Ventricular Dysplasia/genetics/metabolism/pathology; Connexin 43/biosynthesis; Gene Expression Regulation; MAP Kinase Kinase 4; Membrane Proteins/genetics/metabolism; Mice; Mice, Transgenic; Myocytes, Cardiac/metabolism/pathology; Phosphoproteins/genetics/metabolism; Rats; Response Elements; Zonula Occludens-1 Protein

Disciplines :

Cardiovascular & respiratory systems

Author, co-author :

Zi, Min

Kimura, Tomomi E.

Liu, Wei

Jin, Jiawei

Higham, Jonathan

Kharche, Sanjay

Hao, Guoliang

Shi, Ying

Shen, Weijian

Prehar, Sukhpal

More authors (8 more)

Language :

English

Title :

Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Publication date :

2011

Journal title :

The Journal of biological chemistry

ISSN :

0021-9258

eISSN :

1083-351X

Volume :

286

Issue :

Pages :

17821-30

Peer reviewed :

Peer reviewed

Additional URL :

http://www.jbc.org/content/286/20/17821.full.pdf+html

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since 16 October 2014

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