Reference : Reconstruction of biochemical networks in microorganisms.
Scientific journals : Article
Life sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/13046
Reconstruction of biochemical networks in microorganisms.
English
Feist, Adam M. [> >]
Herrgard, Markus J. [> >]
Thiele, Ines mailto []
Reed, Jennie L. [> >]
Palsson, Bernhard O. [> >]
2009
Nature Reviews. Microbiology
7
2
129-43
Yes (verified by ORBilu)
1740-1526
1740-1534
England
[en] Bacteria/genetics/metabolism ; Gene Expression Regulation, Bacterial/physiology ; Genome, Bacterial ; Metabolomics
[en] Systems analysis of metabolic and growth functions in microbial organisms is rapidly developing and maturing. Such studies are enabled by reconstruction, at the genomic scale, of the biochemical reaction networks that underlie cellular processes. The network reconstruction process is organism specific and is based on an annotated genome sequence, high-throughput network-wide data sets and bibliomic data on the detailed properties of individual network components. Here we describe the process that is currently used to achieve comprehensive network reconstructions and discuss how these reconstructions are curated and validated. This review should aid the growing number of researchers who are carrying out reconstructions for particular target organisms.
http://hdl.handle.net/10993/13046

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