| Reference : Mapping of the Mod-1 locus on mouse chromosome 9. |
| Scientific journals : Article | |||
| Life sciences : Genetics & genetic processes | |||
| http://hdl.handle.net/10993/1272 | |||
| Mapping of the Mod-1 locus on mouse chromosome 9. | |
| English | |
| Nass, S. J. [> >] | |
| Olowson, M. [> >] | |
| Miyashita, N. [> >] | |
| Moriwaki, K. [> >] | |
Balling, Rudi  [] | |
| Imai, K. [> >] | |
| 1993 | |
| Mammalian Genome : Official Journal of the International Mammalian Genome Society | |
| 4 | |
| 6 | |
| 333-7 | |
| Yes (verified by ORBilu) | |
| 0938-8990 | |
| 1432-1777 | |
| UNITED STATES | |
| [en] Animals ; Chromosome Mapping ; Crosses, Genetic ; Malate Dehydrogenase/genetics ; Mice ; Mice, Inbred C57BL ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length | |
| [en] A new method for typing the Mod-1 locus on mouse Chromosome (Chr) 9 was developed, based on restriction fragment length polymorphism (RFLP) within a polymerase chain reaction (PCR)-amplified fragment. The new method led us to revise the strain distribution pattern (SDP) of Mod-1 in the BXD (C57BL/6J x DBA/2J) and AKXD (AKR/J x DBA/2J) recombinant inbred (RI) strains. The new SDP eliminates several previously reported examples of double recombination events between Mod-1 and the closest flanking loci in the BXD and AKXD strains. In the BXD strains, the revised SDP of Mod-1 was identical to that of the Mod-1-related D9Rtil locus. Thus, the identity of D9Rtil as a Mod-1-related locus rather than Mod-1 itself is in question. The method was also applied to an interspecific backcross panel between an inbred strain of Mus musculus molossinus (MSM/Ms) and C57BL/6J to map Mod-1 with respect to surrounding microsatellite loci, defining the proximal localization of Mod-1 with respect to D9Mit10 with a genetic distance of 0.6 +/- 0.6 cM. | |
| http://hdl.handle.net/10993/1272 |
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