Reference : Computational infrastructures for data and knowledge management in systems biology

	Document type :	Parts of books : Contribution to collective works
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology Human health sciences : Multidisciplinary, general & others
	To cite this reference:	http://hdl.handle.net/10993/1248

Title :	Computational infrastructures for data and knowledge management in systems biology
Language :	English
Author, co-author :	Georgatos, Fotis [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
	Ballereau, S. [> >]
	Pellet, J. [> >]
	Ghanem, M. [> >]
	Price, N. [> >]
	Hood, Leroy [> >]
	Guo, Y. K. [> >]
	Boutigny, D. [> >]
	Auffray, C. [> >]
	Balling, Rudi [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
	Schneider, Reinhard [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Publication date :	2013
Main document title :	Systems Biology: Integrative Biology and Simulation Tools
Editor :	Prokop, Ales
	Csukás, Bela
Publisher :	Springer
Peer reviewed :	Yes
Keywords :	[en] bioinformatics, infrastructures, information technology, knowledge management, systems biology, translational research, data ; centers, storage, computational science, computational infrastructures, computing, scientific computing, e-science, data management, high ; performance computing, cluster, grid, desktop grid, cloud.
Abstract :	[en] The volume, complexity and heterogeneity of data originating from high throughput functional genomics technologies have created challenges and opportunities for Information Technology (IT) departments. These increased demands have also led to increasing costs for IT infrastructure such as necessary computing power and storage devices, as well as further costs for manpower effort, required for maintenance. This chapter describes some of the challenges for computational analysis infrastructure, including bottlenecks and most pressing needs that have to be addressed to effectively support the development of systems biology and its application in medicine.
Research centres :	Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group) ; Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group)
Permalink :	http://hdl.handle.net/10993/1248
DOI :	10.1007/978-94-007-6803-1_13
Commentary :	in press

	File(s) associated to this reference
	Fulltext file(s): File Commentary Version Size Access Limited access Georgatos Fotis, Balling, Schneider book chapter 1 2013.pdf Author preprint 235.22 kB Request a copy

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