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ZAGARE Alise

University of Luxembourg > Luxembourg Centre for Systems Biomedicine > Developmental and Cellular Biology > Team Jens Christian SCHWAMBORN

Main Referenced Co-authors
SCHWAMBORN, Jens Christian  (12)
ANTONY, Paul  (6)
BARMPA, Kyriaki  (4)
KRÜGER, Rejko  (4)
ARENA, Giuseppe  (3)
Main Referenced Keywords
Humans (4); Neurology (clinical) (4); Parkinson Disease/metabolism (4); Dopaminergic Neurons/metabolism (3); Medicine (miscellaneous) (3);
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (9)
Biochemistry, biophysics & molecular biology (3)
Biotechnology (3)
Genetics & genetic processes (1)

Publications (total 15)

The most downloaded
640 downloads
ZAGARE, A. (2023). Contribution of Type 2 Diabetes and genetic variants in LRRK2 and GBA to Parkinson's disease [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58118 https://hdl.handle.net/10993/58118

The most cited

1332 citations (OpenAlex)

HEIRENDT, L., Arreckx, S., PFAU, T., Mendoza, S. N., Richelle, A., Heinken, A. K., Haraldsdottir, H. S., Wachowiak, J., Keating, S. M., VLASOV, V., Magnusdottir, S., Ng, C. Y., Preciat, G., ZAGARE, A., Chan, S. H. J., Aurich, M. K., Clancy, C. M., Modamio, J., Sauls, J. T., ... Fleming, R. M. T. (2019). Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0. Nature Protocols, 14 (3), 639-702. doi:10.1038/s41596-018-0098-2 https://hdl.handle.net/10993/39264

ZUCCOLI, E., Al Sawaf, H., Tuzza, M., Nickels, S. L., ZAGARE, A., & SCHWAMBORN, J. C. (17 October 2025). Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling. iScience, 28 (10), 113541. doi:10.1016/j.isci.2025.113541
Peer Reviewed verified by ORBi

CHEMLA, A., ARENA, G., SACRIPANTI, G., BARMPA, K., ZAGARE, A., GARCIA, P., GORGOGIETAS, V., ANTONY, P., OHNMACHT, J., BARON, A., Jung, J., Lind-Holm Mogensen, F., MICHELUCCI, A., MARZESCO, A.-M., BUTTINI, M., Schmidt, T., GRÜNEWALD, A., SCHWAMBORN, J. C., KRÜGER, R., & SARAIVA, C. (03 October 2025). Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss. Brain: a Journal of Neurology, 148 (10), 3607 - 3622. doi:10.1093/brain/awaf051
Peer Reviewed verified by ORBi

GOMEZ GIRO, G., FRANGENBERG-HOFF, D., VEGA GUTIERREZ, D. M., ZAGARE, A., BARMPA, K., ANTONY, P., ROBERTSON, G., Sabahi-Kaviani, R., Haendler, K., Kruse, N., Papastefanaki, F., Matsas, R., Spielmann, M., Luttge, R., & SCHWAMBORN, J. C. (May 2025). α-Synuclein Pathology Spreads in a Midbrain-Hindbrain Assembloid Model. Advanced Science, 12 (20), 2409040. doi:10.1002/advs.202409040
Peer reviewed

ZAGARE, A., SAUTER, T., BARMPA, K., PIRES PACHECO, M. I., KRÜGER, R., SCHWAMBORN, J. C., & SARAIVA, C. (17 April 2025). MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson's disease-associated dopaminergic neuron loss. NPJ Systems Biology and Applications, 11 (1), 37. doi:10.1038/s41540-025-00509-x
Peer Reviewed verified by ORBi

ZAGARE, A., BALAUR, I.-A., ROUGNY, A., SARAIVA, C., GOBIN, M., MONZEL, A. S., GHOSH, S., SATAGOPAM, V., & SCHWAMBORN, J. C. (31 March 2025). Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis. NPJ Parkinson's Disease, 11 (1), 63. doi:10.1038/s41531-025-00914-3
Peer Reviewed verified by ORBi

ZAGARE, A., Kurlovics, J., ALMEIDA, C., FERRANTE, D., FRANGENBERG-HOFF, D., VITALI, A., GOMEZ GIRO, G., JÄGER, C., ANTONY, P., HALDER, R., KRÜGER, R., GLAAB, E., Stalidzans, E., ARENA, G., & SCHWAMBORN, J. C. (28 January 2025). Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson's disease pathology. Journal of Tissue Engineering, 16, 20417314241295928. doi:10.1177/20417314241295928
Peer Reviewed verified by ORBi

Mommaerts, K., Monzel, A. S., ZAGARE, A., NICKELS, S., DIEDERICH, N., LONGHINO, L., Mathieson, W., ANTONY, P., BETSOU, F., & SCHWAMBORN, J. C. (24 January 2025). Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson's Disease. Parkinson's Disease, 2025 (1), 5149071. doi:10.1155/padi/5149071
Peer Reviewed verified by ORBi

ZAGARE, A., HEMEDAN, A., ALMEIDA, C., Frangenberg, D., Gomez-Giro, G., ANTONY, P., HALDER, R., Krüger, R., GLAAB, E., OSTASZEWSKI, M., ARENA, G., & SCHWAMBORN, J. C. (2024). Insulin Resistance Is a Modifying Factor for Parkinson's Disease. Movement Disorders. doi:10.1002/mds.30039
Peer Reviewed verified by ORBi

ZAGARE, A., Preciat, G., NICKELS, S. L., Luo, X., MONZEL, A. S., Gomez-Giro, G., ROBERTSON, G., Jaeger, C., Sharif, J., Koseki, H., DIEDERICH, N., GLAAB, E., FLEMING, R. M., & SCHWAMBORN, J. C. (20 November 2023). Omics data integration suggests a potential idiopathic Parkinson's disease signature. Communications Biology, 6 (1), 1179. doi:10.1038/s42003-023-05548-w
Peer Reviewed verified by ORBi

ZAGARE, A. (2023). Contribution of Type 2 Diabetes and genetic variants in LRRK2 and GBA to Parkinson's disease [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58118

ZAGARE, A., BARMPA, K., SMAJIC, S., SMITS, L., GRZYB, K., GRÜNEWALD, A., SKUPIN, A., NICKELS, S. L., & SCHWAMBORN, J. C. (2022). Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression. American Journal of Human Genetics. doi:10.1016/j.ajhg.2021.12.009
Peer Reviewed verified by ORBi

ZAGARE, A., GOBIN, M., Monzel, A., & SCHWAMBORN, J. C. (2021). A robust protocol for the generation of human midbrain organoids. STAR Protocols. doi:10.1016/j.xpro.2021.100524
Peer Reviewed verified by ORBi

MONZEL, A. S., Hemmer, K., SMITS, L., BOLOGNIN, S., Lucarelli, P., ROSETY, I., ZAGARE, A., ANTONY, P., Nickels, S., KRÜGER, R., & SCHWAMBORN, J. C. (2020). Machine learning-assisted neurotoxicity prediction in human midbrain organoids. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2020.05.011
Peer Reviewed verified by ORBi

HEIRENDT, L., Arreckx, S., PFAU, T., Mendoza, S. N., Richelle, A., Heinken, A. K., Haraldsdottir, H. S., Wachowiak, J., Keating, S. M., VLASOV, V., Magnusdottir, S., Ng, C. Y., Preciat, G., ZAGARE, A., Chan, S. H. J., Aurich, M. K., Clancy, C. M., Modamio, J., Sauls, J. T., ... Fleming, R. M. T. (2019). Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0. Nature Protocols, 14 (3), 639-702. doi:10.1038/s41596-018-0098-2
Peer Reviewed verified by ORBi

NORONHA, A., MODAMIO CHAMARRO, J., JAROSZ, Y., GUERARD, E., Sompairac, N., PRECIAT GONZALEZ, G. A., DANIELSDOTTIR, A. D., KRECKE, M., MERTEN, D., HARALDSDOTTIR, H., HEINKEN, A. K., HEIRENDT, L., MAGNUSDOTTIR, S., RAVCHEEV, D., SAHOO, S., GAWRON, P., FRISCIONI, L., GARCIA SANTA CRUZ, B., Prendergast, M., ... THIELE, I. (2018). The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Research. doi:10.1093/nar/gky992
Peer Reviewed verified by ORBi

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