OHNMACHT Jochen

University of Luxembourg

Main Referenced Co-authors

KRÜGER, Rejko (4)

ANTONY, Paul (3)

Becker, Catherina (3)

Becker, Thomas (3)

SINKKONEN, Lasse (3)

Main Referenced Keywords

A30P (1); ACKR3 (1); Chemokine Receptor (1); Gene regulation (1); Genetic modifier (1);

Main Referenced Unit & Research Centers

Department of Life Sciences and Medicine (DLSM) (1)

Luxembourg Centre for Systems Biomedicine (LCSB) (1)

Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) (1)

Main Referenced Disciplines

Biochemistry, biophysics & molecular biology (8)

Genetics & genetic processes (5)

Life sciences: Multidisciplinary, general & others (3)

Neurology (1)

Human health sciences: Multidisciplinary, general & others (1)

Publications (total 9)

Search in publications

The most downloaded

444 downloads

Wasner, K., Smajic, S., Ghelfi, J., Delcambre, S., Prada-Medina, C. A., Knappe, E., Arena, G., Mulica, P., Agyeah, G., Rakovic, A., Boussaad, I., Badanjak, K., Ohnmacht, J., Gerardy, J.-J., Takanashi, M., Trinh, J., Mittelbronn, M., Hattori, N., Klein, C., ... Grünewald, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025 https://hdl.handle.net/10993/51271

The most cited

102 citations (OpenCitations)

Reimer, M., Norris, A., Ohnmacht, J., Patani, R., Zhong, Z., Dias, T., Kuscha, V., Scott, A., Chen, Y.-C., Rozov, S., Frazer, S., Wyatt, C., Higashijma, S.-I., Patton, E., Panula, P., Chandran, S., Becker, T., & Becker, C. (10 June 2013). Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration. Developmental Cell, 25 (5), 478-491. doi:10.1016/j.devcel.2013.04.012 https://hdl.handle.net/10993/30440

Wasner, K., Smajic, S., Ghelfi, J., Delcambre, S., Prada-Medina, C. A., Knappe, E., Arena, G., Mulica, P., Agyeah, G., Rakovic, A., Boussaad, I., Badanjak, K., Ohnmacht, J., Gerardy, J.-J., Takanashi, M., Trinh, J., Mittelbronn, M., Hattori, N., Klein, C., ... Grünewald, A. (2022). Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation. Movement disorders : official journal of the Movement Disorder Society. doi:10.1002/mds.29025

https://hdl.handle.net/10993/51271

Peer reviewed

Barbuti, P. A., Ohnmacht, J., Santos, B. F., Antony, P., Massart, F., Cruciani, G., Dording, C. M., Pavelka, L., Casadei, N., Kwon, Y.-J., & Krüger, R. (09 November 2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11, 21946. doi:10.1038/s41598-021-01505-x

https://hdl.handle.net/10993/48941

Peer Reviewed verified by ORBi

Gui, Y., Grzyb, K., Thomas, M., Ohnmacht, J., Garcia, P., Buttini, M., Skupin, A., Sauter, T., & Sinkkonen, L. (2021). Single‑nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell‑type‑specific gene regulatory variation. Epigenetics and Chromatin. doi:10.1186/s13072-021-00418-3

https://hdl.handle.net/10993/48331

Peer Reviewed verified by ORBi

Walter, J., Bolognin, S., Poovathingal, S., Magni, S., Gerard, D., Antony, P., Nickels, S. L., Salamanca, L., Berger, E., Smits, L., Grzyb, K., Perfeito, R., Hoel, F., Qing, X., Ohnmacht, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... Schwamborn, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864

https://hdl.handle.net/10993/48898

Peer Reviewed verified by ORBi

Ohnmacht, J., May, P., Sinkkonen, L., & Krüger, R. (2020). Missing heritability in Parkinson’s disease: the emerging role of non‑coding genetic variation. Journal of Neural Transmission. doi:10.1007/s00702-020-02184-0

https://hdl.handle.net/10993/43016

Peer Reviewed verified by ORBi

Meyrath, M., Szpakowska, M., Zeiner, J., Massotte, L., Merz, M. P., Benkel, T., Simon, K., Ohnmacht, J., Turner, J., Krüger, R., Seutin, V., Ollert, M., Kostenis, E., & Chevigné, A. (2020). The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nature Communications, 11 (1), 3033. doi:10.1038/s41467-020-16664-0

https://hdl.handle.net/10993/43590

Peer Reviewed verified by ORBi

Ohnmacht, J.* , Yang, Y.* , Maurer, G., Barreiro-Iglesias, A., Tsarouchas, T., Wehner, D., Sieger, D., Becker, C., & Becker, T. (01 May 2016). Spinal motor neurons are regenerated after mechanical lesion and genetic ablation in larval zebrafish. Development, 143 (9), 1464-1474. doi:10.1242/dev.129155

https://hdl.handle.net/10993/30442

Peer Reviewed verified by ORBi

* These authors have contributed equally to this work.

Reimer, M., Norris, A., Ohnmacht, J., Patani, R., Zhong, Z., Dias, T., Kuscha, V., Scott, A., Chen, Y.-C., Rozov, S., Frazer, S., Wyatt, C., Higashijma, S.-I., Patton, E., Panula, P., Chandran, S., Becker, T., & Becker, C. (10 June 2013). Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration. Developmental Cell, 25 (5), 478-491. doi:10.1016/j.devcel.2013.04.012

https://hdl.handle.net/10993/30440

Peer Reviewed verified by ORBi

Zhong, Z., Ohnmacht, J., Reimer, M., Bach, I., Becker, T., & Becker, C. (28 March 2012). Chondrolectin Mediates Growth Cone Interactions of Motor Axons with an Intermediate Target. Journal of Neuroscience, 32 (13), 4426-4439. doi:10.1523/JNEUROSCI.5179-11.2012

https://hdl.handle.net/10993/30441

Peer Reviewed verified by ORBi