Gomez Ramos, B., Ohnmacht, J., de Lange, N., VALCESCHINI, E., GINOLHAC, A., CATILLON, M., FERRANTE, D., Rakovic, A., HALDER, R., Massart, F., ARENA, G., ANTONY, P., BOLOGNIN, S., Klein, C., KRAUSE, R., Schulz, M. H., SAUTER, T., Krüger, R., & SINKKONEN, L. (2023). Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. EMBO Reports. doi:10.1038/s44319-023-00024-2 Peer Reviewed verified by ORBi |
GAVRIIL, M., PROIETTO, M., PACZIA, N., GINOLHAC, A., HALDER, R., VALCESCHINI, E., SAUTER, T., LINSTER, C., & SINKKONEN, L. (November 2023). 2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition. Life Science Alliance, 7 (2), 202302333. doi:10.26508/lsa.202302333 Peer Reviewed verified by ORBi |
BESSERON, X., & GINOLHAC, A. (2023). Result Verification of Multi-physics Simulations and Transcriptomics Analyses on Processor AWS Graviton3. |
TERNES, D., TSENKOVA, M., POZDEEV, V., MEYERS, M., KONCINA, E., ATATRI, S., SCHMITZ, M., KARTA, J., SCHMOETTEN, M., Heinken, A., RODRIGUEZ, F., Delbrouck, C., GAIGNEAUX, A., GINOLHAC, A., Dan Nguyen, T. T., Grandmougin, L., Frachet-Bour, A., Martin-Gallausiaux, C., PIRES PACHECO, M. I., ... LETELLIER, E. (2022). The gut microbial metabolite formate exacerbates colorectal cancer progression. Nature Metabolism. doi:10.1038/s42255-022-00558-0 Peer Reviewed verified by ORBi |
Del Mistro, G., Riemann, S., Schindler, S., Beissert, S., Kontermann, R. E., GINOLHAC, A., Halder, R., PRESTA, L., SINKKONEN, L., SAUTER, T., & Kulms, D. (2022). Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma. Cell Death and Disease. doi:10.1038/s41419-022-04502-8 Peer Reviewed verified by ORBi |
GRANDBARBE, L., MICHELUCCI, A., HEUSCHLING, P., PAVLOU, M. A., & GINOLHAC, A. (2021). NF-κB and TNF Affect the Astrocytic Differentiation from Neural Stem Cells. Cells. doi:10.3390/cells10040840 Peer Reviewed verified by ORBi |
KIRCHMEYER, M., SERVAIS, F., GINOLHAC, A., Nazarov, P. V., MARGUE, C., PHILIPPIDOU, D., Nicot, N., BEHRMANN, I., HAAN, C., & KREIS, S. (2020). Systematic transcriptional profiling of responses to STAT1- and STAT3- activating cytokines in different cancer types. Journal of Molecular Biology. doi:10.1016/j.jmb.2020.09.011 Peer Reviewed verified by ORBi |
Shahraz, A., Wißfeld, J., GINOLHAC, A., Matthews, M., SINKKONEN, L., & Neumann, H. (2020). Phagocytosis‐related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides. Glia. doi:10.1002/glia.23890 Peer Reviewed verified by ORBi |
TERNES, D., KARTA, J., TSENKOVA, M., KONCINA, E., SCHMITZ, M., GRANDMOUGIN, L., GINOLHAC, A., GAIGNEAUX, A., RAMIRO GARCIA, J., WILMES, P., HAAN, S., & LETELLIER, E. (22 February 2020). Understanding the role of Fusobacterium nucleatum metabolism in colon cancer initiation and progression [Poster presentation]. The Microbiome, Viruses, and Cancer, Orlando, United States. |
Klaus, C., Hansen, J. N., GINOLHAC, A., GERARD, D., Gnanapragassam, V. S., Horstkorte, R., Rossdam, C., Buettner, F. F. R., SAUTER, T., SINKKONEN, L., Neumann, H., & Linnartz-Gerlach, B. (2020). Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2020.01.008 Peer Reviewed verified by ORBi |
BECKER, J. C., GERARD, D., GINOLHAC, A., SAUTER, T., & SINKKONEN, L. (2019). Identification of genes under dynamic post-transcriptional regulation from time-series epigenomic data. Epigenomics. doi:10.2217/epi-2018-0084 Peer Reviewed verified by ORBi |
Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Ruther, P. L., Fotakis, A. K., Lyon, D., Moreno-Mayar, J. V., Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, M., GINOLHAC, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W. J., Chan, Y. L., ... Willerslev, E. (2019). Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny. Nature. doi:10.1038/s41586-019-1555-y Peer Reviewed verified by ORBi |
GERARD, D., Schmidt, F., GINOLHAC, A., SCHMITZ, M., HALDER, R., Ebert, P., Schulz, M., SAUTER, T., & SINKKONEN, L. (2018). Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency. Nucleic Acids Research. doi:10.1093/nar/gky1240 Peer Reviewed verified by ORBi |
Linnartz-Gerlach, B., Bodea, L.-G., Klaus, C., GINOLHAC, A., HALDER, R., SINKKONEN, L., Walter, J., Colonna, M., & Neumann, H. (2018). TREM2 triggers microglial density and age‐related neuronal loss. Glia. doi:10.1002/glia.23563 Peer Reviewed verified by ORBi |
GINOLHAC, A., Emeras, J., VARRETTE, S., PLUGARU, V., DIEHL, S., PARISOT, C., CARTIAUX, H., & BOUVRY, P. (June 2018). UL HPC Tutorial: Statistical Computing with R [Paper presentation]. 7th High Performance Computing School, University of Luxembourg, Luxembourg. |
ROLVERING, C., ZIMMER, A. D., GINOLHAC, A., MARGUE, C., KIRCHMEYER, M., SERVAIS, F., Hermanns, H. M., Hergovits, S., Nazarov, P. V., Nicot, N., KREIS, S., HAAN, S., BEHRMANN, I., & HAAN, C. (2018). The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by a-PD-L1 or a-IL6 antibodies. Journal of Leukocyte Biology, 104, 969-985. doi:10.1002/JLB.MA1217-495R Peer Reviewed verified by ORBi |
Kirchmeyer, M., SERVAIS, F., Hamdorf, M., Nazarov, P. V., GINOLHAC, A., HALDER, R., Vallar, L., Glanemann, M., Rubie, C., Lammert, F., KREIS, S., & BEHRMANN, I. (2018). Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets. Journal of Leukocyte Biology. doi:10.1002/JLB.MA1217-499RR Peer Reviewed verified by ORBi |
ULLMANN, P., RODRIGUEZ, F., SCHMITZ, M., Meurer, S. K., Qureshi-Baig, K., FELTEN, P., GINOLHAC, A., Antunes, L., Frasquilho, S., Zugel, N., Weiskirchen, R., HAAN, S., & LETELLIER, E. (2018). The microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis. Cancer Research. doi:10.1158/0008-5472.CAN-17-3003 Peer Reviewed verified by ORBi |
LETELLIER, E., GINOLHAC, A., Schmitz Martine, & HAAN, S. (2018). NOVEL BIOMARKERS FOR CANCER DIAGNOSIS, PREDICTION OR STAGING. |
LETELLIER, E., SCHMITZ, M., GINOLHAC, A., RODRIGUEZ, F., ULLMANN, P., Qureshi-Baig, K., Frasquilho, S., Antunes, L., & HAAN, S. (21 November 2017). Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence. British Journal of Cancer, 117 (11), 1689-1701. doi:10.1038/bjc.2017.352 Peer Reviewed verified by ORBi |
ROLVERING, C., Zimmer, A., KOZAR, I., Hermanns, LETELLIER, E., Vallar, L., Nazarov, P., Nicot, N., GINOLHAC, A., HAAN, S., BEHRMANN, I., & HAAN, C. (2017). Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines. Biochimica et Biophysica Acta. Molecular Cell Research, 516-526. doi:10.1016/J.BBAMCR.2016.12.006 Peer Reviewed verified by ORBi |
ULLMANN, P., qureshi-baig, K., RODRIGUEZ, F., GINOLHAC, A., nonnenmacher, Y., TERNES, D., Weiler, J., Gaebler, K., bahlawane, C., hiller, K., HAAN, S., & LETELLIER, E. (04 October 2016). Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. Oncotarget, 7 (40), 97-114. doi:10.18632/oncotarget.11772 Peer Reviewed verified by ORBi |
Reinsbach, S., WIENECKE, A., GINOLHAC, A., Vallar, L., Krishna, Krishna, A., Nazarov, P., MAY, P., & KREIS, S. (2016). “Melanomics”: analysis and integration of whole genomes, transcriptomes and miRNomes of primary melanoma patients. European Journal of Cancer, 61 (Suppl.1), 32. doi:10.1016/S0959-8049(16)61101-2 |
DOROSZ, S. A., GINOLHAC, A., Kähne, T., Naumann, M., SAUTER, T., SALSMANN, A., & BUEB, J.-L. (2015). Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells. Mediators of Inflammation, 2015, 1-16. doi:10.1155/2015/737310 Peer Reviewed verified by ORBi |
Der Sarkissian, C., Ermini, L., Schubert, M., Yang, M. A., Librado, P., Fumagalli, M., Jonsson, H., Bar-Gal, G. K., Albrechtsen, A., Vieira, F. G., Petersen, B., GINOLHAC, A., Seguin-Orlando, A., Magnussen, K., Fages, A., Gamba, C., Lorente-Galdos, B., Polani, S., Steiner, C., ... Orlando, L. (2015). Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse. Current Biology, 25 (19), 2577-83. doi:10.1016/j.cub.2015.08.032 Peer Reviewed verified by ORBi |
Jonsson, H., Schubert, M., Seguin-Orlando, A., GINOLHAC, A., Petersen, L., Fumagalli, M., Albrechtsen, A., Petersen, B., Korneliussen, T. S., Vilstrup, J. T., Lear, T., Myka, J. L., Lundquist, J., Miller, D. C., Alfarhan, A. H., Alquraishi, S. A., Al-Rasheid, K. A. S., Stagegaard, J., Strauss, G., ... Orlando, L. (2014). Speciation with gene flow in equids despite extensive chromosomal plasticity. Proceedings of the National Academy of Sciences of the United States of America, 111 (52), 18655-60. doi:10.1073/pnas.1412627111 Peer Reviewed verified by ORBi |
Schubert, M., Ermini, L., Der Sarkissian, C., Jonsson, H., GINOLHAC, A., Schaefer, R., Martin, M. D., Fernandez, R., Kircher, M., McCue, M., Willerslev, E., & Orlando, L. (2014). Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX. Nature Protocols, 9 (5), 1056-82. doi:10.1038/nprot.2014.063 Peer Reviewed verified by ORBi |
Schubert, M., Jonsson, H., Chang, D., Der Sarkissian, C., Ermini, L., GINOLHAC, A., Albrechtsen, A., Dupanloup, I., Foucal, A., Petersen, B., Fumagalli, M., Raghavan, M., Seguin-Orlando, A., Korneliussen, T. S., Velazquez, A. M. V., Stenderup, J., Hoover, C. A., Rubin, C.-J., Alfarhan, A. H., ... Orlando, L. (2014). Prehistoric genomes reveal the genetic foundation and cost of horse domestication. Proceedings of the National Academy of Sciences of the United States of America, 111 (52), 5661-9. doi:10.1073/pnas.1416991111 Peer Reviewed verified by ORBi |
Orlando, L.* , GINOLHAC, A.* , Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Vilstrup, J. T., Raghavan, M., Korneliussen, T., Malaspinas, A.-S., Vogt, J., Szklarczyk, D., Kelstrup, C. D., ... Willerslev, E. (2013). Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse. Nature, 499 (7456), 74-8. doi:10.1038/nature12323 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Vilstrup, J. T., Seguin-Orlando, A., Stiller, M., GINOLHAC, A., Raghavan, M., Nielsen, S. C. A., Weinstock, J., Froese, D., Vasiliev, S. K., Ovodov, N. D., Clary, J., Helgen, K. M., Fleischer, R. C., Cooper, A., Shapiro, B., & Orlando, L. (2013). Mitochondrial phylogenomics of modern and ancient equids. PLoS ONE, 8 (2), 55950. doi:10.1371/journal.pone.0055950 Peer Reviewed verified by ORBi |
Jonsson, H., GINOLHAC, A., Schubert, M., Johnson, P. L. F., & Orlando, L. (2013). mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters. Bioinformatics, 29 (13), 1682-4. doi:10.1093/bioinformatics/btt193 Peer reviewed |
Cappellini, E., Jensen, L. J., Szklarczyk, D., GINOLHAC, A., da Fonseca, R. A. R., Stafford, T. W., Holen, S. R., Collins, M. J., Orlando, L., Willerslev, E., Gilbert, M. T. P., & Olsen, J. V. (2012). Proteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins. Journal of Proteome Research, 11 (2), 917-26. doi:10.1021/pr200721u Peer Reviewed verified by ORBi |
GINOLHAC, A., Vilstrup, J., Stenderup, J., Rasmussen, M., Stiller, M., Shapiro, B., Zazula, G., Froese, D., Steinmann, K. E., Thompson, J. F., Al-Rasheid, K. A. S., Gilbert, T. M. P., Willerslev, E., & Orlando, L. (2012). Improving the performance of true single molecule sequencing for ancient DNA. BMC Genomics, 13, 177. doi:10.1186/1471-2164-13-177 Peer Reviewed verified by ORBi |
Schubert, M., GINOLHAC, A., Lindgreen, S., Thompson, J. F., Al-Rasheid, K. A. S., Willerslev, E., Krogh, A., & Orlando, L. (2012). Improving ancient DNA read mapping against modern reference genomes. BMC Genomics, 13, 178. doi:10.1186/1471-2164-13-178 Peer Reviewed verified by ORBi |
Orlando, L., GINOLHAC, A., Raghavan, M., Vilstrup, J., Rasmussen, M., Magnussen, K., Steinmann, K. E., Kapranov, P., Thompson, J. F., Zazula, G., Froese, D., Moltke, I., Shapiro, B., Hofreiter, M., Al-Rasheid, K. A. S., Gilbert, M. T. P., & Willerslev, E. (2011). True single-molecule DNA sequencing of a pleistocene horse bone. Genome Research, 21 (10), 1705-19. doi:10.1101/gr.122747.111 Peer Reviewed verified by ORBi |
GINOLHAC, A., Rasmussen, M., Gilbert, M. T. P., Willerslev, E., & Orlando, L. (2011). mapDamage: testing for damage patterns in ancient DNA sequences. Bioinformatics, 27 (15), 2153-5. doi:10.1093/bioinformatics/btr347 Peer reviewed |
Lefevre, F., Robe, P., Jarrin, C., GINOLHAC, A., Zago, C., Auriol, D., Vogel, T. M., Simonet, P., & Nalin, R. (April 2008). Drugs from hidden bugs: their discovery via untapped resources. Research in Microbiology, 159 (3), 153-61. doi:10.1016/j.resmic.2007.12.011 Peer Reviewed verified by ORBi |
GINOLHAC, A., Jarrin, C., Robe, P., Perrière, G., Vogel, T. M., Simonet, P., & Nalin, R. (June 2005). Type I polyketide synthases may have evolved through horizontal gene transfer. Journal of Molecular Evolution, 60 (6), 716-25. doi:10.1007/s00239-004-0161-1 Peer Reviewed verified by ORBi |
GINOLHAC, A.* , Jarrin, C.* , Gillet, B., Robe, P., Pujic, P., Tuphile, K., Bertrand, H., Vogel, T. M., Perrière, G., Simonet, P., & Nalin, R. (September 2004). Phylogenetic analysis of polyketide synthase I domains from soil metagenomic libraries allows selection of promising clones. Applied and Environmental Microbiology, 70 (9), 5522-7. doi:10.1128/AEM.70.9.5522-5527.2004 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Armengaud, C., Causse, N., Aït-Oubah, J., GINOLHAC, A., & Gauthier, M. (24 March 2000). Functional cytochrome oxidase histochemistry in the honeybee brain. Brain Research, 859 (2), 390-3. doi:10.1016/s0006-8993(00)02016-3 Peer Reviewed verified by ORBi |