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BRECHARD Sabrina

University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)

Main Referenced Co-authors
TSCHIRHART, Eric  (15)
PLANÇON, Sébastien  (8)
SCHENTEN, Véronique  (8)
BUEB, Jean-Luc  (7)
MELCHIOR, Chantal  (6)
Main Referenced Keywords
neutrophils (5); cytokines (4); inflammation (4); cytokine secretion (3); degranulation (3);
Main Referenced Unit & Research Centers
Life Sciences Research Unit (LSRU): Immune Cells and Inflammatory Diseases (ICID) (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (18)
Anatomy (cytology, histology, embryology...) & physiology (2)

Publications (total 20)

The most downloaded
263 downloads
Bréchard, S., Plançon, S., & Tschirhart, E. (2013). New Insights into the Regulation of Neutrophil NADPH Oxidase Activity in the Phagosome: A Focus on the Role of Lipid and Ca(2+) Signaling. Antioxidants & Redox Signaling, 18 (6), 661-676. doi:10.1089/ars.2012.4773 https://hdl.handle.net/10993/8296

The most cited

159 citations (Scopus®)

Bréchard, S., & Tschirhart, E. (2008). Regulation of superoxide production in neutrophils: role of calcium influx. Journal of Leukocyte Biology, 84 (5), 1223-1237. doi:10.1189/jlb.0807553 https://hdl.handle.net/10993/5743

ZHOU, Y., & BRECHARD, S. (21 October 2022). Neutrophil Extracellular Vesicles: A Delicate Balance between Pro-Inflammatory Responses and Anti-Inflammatory Therapies. Cells, 11 (20), 3318. doi:10.3390/cells11203318
Peer Reviewed verified by ORBi

Zhou, Y., Hann, J., Schenten, V., Plancon, S., Bueb, J.-L., Tolle, F., & Brechard, S. (2021). Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors. International Journal of Molecular Sciences. doi:10.3390/ijms22168845
Peer Reviewed verified by ORBi

Jung, N., Bueb, J.-L., Tolle, F., & Bréchard, S. (2019). Regulation of neutrophil pro-inflammatory functions sheds new light on the pathogenesis of rheumatoid arthritis. Biochemical Pharmacology, 165, 170-180. doi:10.1016/j.bcp.2019.03.010
Peer Reviewed verified by ORBi

Hann, J., Bueb, J.-L., Tolle, F., & Bréchard, S. (2019). Calcium signaling and regulation of neutrophil functions: Still a long way to go. Journal of Leukocyte Biology, 1-13. doi:10.1002/JLB.3RU0719-241R
Peer Reviewed verified by ORBi

Jung, N., Schenten, V., Bueb, J.-L., Tolle, F., & Bréchard, S. (2019). miRNAs Regulate Cytokine Secretion Induced by Phosphorylated S100A8/A9 in Neutrophils. International Journal of Molecular Sciences, 20 (22). doi:10.3390/ijms20225699
Peer Reviewed verified by ORBi

Schenten, V., Plancon, S., Jung, N., Hann, J., Bueb, J.-L., Bréchard, S., Tschirhart, E., & Tolle, F. (March 2018). Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9. Frontiers in Immunology, 9, 447. doi:10.3389/fimmu.2018.00447
Peer Reviewed verified by ORBi

Naegelen, I., Beaume, N., Plançon, S., Schenten, V., Tschirhart, E., & Bréchard, S. (22 October 2015). Regulation of Neutrophil Degranulation and Cytokine Secretion: A Novel Model Approach Based on Linear Fitting. Journal of Immunology Research, 2015, 1-15. doi:10.1155/2015/817038
Peer reviewed

Naegelen, I., Plançon, S., Nicot, N., Kaoma, T., Muller, A., Vallar, L., Tschirhart, E., & Bréchard, S. (29 December 2014). An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells. Journal of Leukocyte Biology, 97. doi:10.1189/jlb.3A0514-254RR
Peer Reviewed verified by ORBi

Bréchard, S., Plançon, S., & Tschirhart, E. (2013). New Insights into the Regulation of Neutrophil NADPH Oxidase Activity in the Phagosome: A Focus on the Role of Lipid and Ca(2+) Signaling. Antioxidants & Redox Signaling, 18 (6), 661-676. doi:10.1089/ars.2012.4773
Peer reviewed

Bréchard, S., Schenten, V., & Tschirhart, E. (2012). Role of the Neutrophil NADPH Oxidase and S100A8/A9 in the Pathophysiology of Chronic Inflammation. In M. Khatami (Ed.), Inflammation, Chronic Diseases and Cancer - Cell and Molecular Biology, Immunology and Clinical Bases (pp. 307-330). InTech. doi:10.5772/25976
Peer reviewed

Steinckwich, N., Schenten, V., Melchior, C., Bréchard, S., & Tschirhart, E. (2011). An essential role of STIM1, Orai1, and S100A8-A9 proteins for Ca2+ signaling and FcγR-mediated phagosomal oxidative activity. Journal of Immunology, 186 (4), 2182-2191. doi:10.4049/jimmunol.1001338
Peer Reviewed verified by ORBi

Schenten, V., Melchior, C., Steinckwich, N., Tschirhart, E., & Bréchard, S. (2011). Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9. Journal of Leukocyte Biology, 89 (4), 587-596. doi:10.1189/jlb.0510304
Peer Reviewed verified by ORBi

Schenten, V., Bréchard, S., Plançon, S., Melchior, C., Frippiat, J.-P., & Tschirhart, E. (2010). iPLA 2 , a novel determinant in Ca2+ - and phosphorylation-dependent S100A8/A9 regulated NOX2 activity. Biochimica et Biophysica Acta-Molecular Cell Research, 1803 (7), 840-847. doi:10.1016/j.bbamcr.2010.02.006
Peer reviewed

Bréchard, S., Salsmann, A., & Tschirhart, E. (2009). OAG induces an additional PKC-, PI3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca 2+ entry. Journal of Leukocyte Biology, 85 (4), 638-647. doi:10.1189/jlb.0508330
Peer Reviewed verified by ORBi

Bréchard, S., Plançon, S., Melchior, C., & Tschirhart, E. (2009). STIM1 but not STIM2 is an essential regulator of Ca2+ influx-mediated NADPH oxidase activity in neutrophil-like HL-60 cells. Biochemical Pharmacology, 78 (5), 504-513. doi:10.1016/j.bcp.2009.05.006
Peer reviewed

Schenten, V., Bréchard, S., Melchior, C., Plançon, S., Salsmann, A., & Tschirhart, E. (2008). Ca2+-dependent regulation of NOX2 activity via MRP proteins in HL-60 granulocytes. Calcium Binding Proteins, 3 (1), 25-30.
Peer Reviewed verified by ORBi

Bréchard, S., Melchior, C., Plançon, S., Schenten, V., & Tschirhart, E. (2008). Store-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes. Cell Calcium, 1-2. doi:10.1016/j.ceca.2008.03.002
Peer Reviewed verified by ORBi

Bréchard, S., & Tschirhart, E. (2008). Regulation of superoxide production in neutrophils: role of calcium influx. Journal of Leukocyte Biology, 84 (5), 1223-1237. doi:10.1189/jlb.0807553
Peer Reviewed verified by ORBi

Bréchard, S., Brunello, A., Bueb, J.-L., & Tschirhart, E. (2006). Modulation by cADPr of Ca2+ mobilization and oxidative response in dimethylsulfoxide- or retinoic acid-differentiated HL-60 cells. Biochimica et Biophysica Acta, 1763 (1), 129-36. doi:10.1016/j.bbamcr.2005.12.003
Peer reviewed

Bréchard, S., Bueb, J.-L., & Tschirhart, E. (2005). Interleukin-8 primes oxidative burst in neutrophil-like HL-60 through changes in cytosolic calcium. Cell Calcium, 37 (6), 531-40. doi:10.1016/j.ceca.2005.01.019
Peer Reviewed verified by ORBi

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