Doctoral thesis (Dissertations and theses)
Development of data integration tools within functional genomics
Teixeira Queiros, Pedro


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Keywords :
bioinformatics; protein function annotation; data integration
Abstract :
[en] Due to technological advances across all scientific domains, data is generated at an extremely fast pace. This is especially true in biology, where advances in computational and sequencing technologies led to the necessity to develop automated methods for data analysis; thus the field of bioinformatics was born. This thesis focuses on one specific field within bioinformatics - functional genomics. To be precise, in the development of techniques and software for the integration of data to generate novel insights. Indeed, as the amount of knowledge increases, so does the need to integrate it systematically. In this context, the work described herein relates to the integration of multiple resources to improve the functional annotation of proteins, which led to the development of two bioinformatic tools - Mantis and UniFunc. For the downstream integration and analysis of functional predictions, a network annotation tool was developed - UniFuncNet, which, together with the previous tools, enables the efficient functional characterisation of individual organisms or communities.
Research center :
- Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group)
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Teixeira Queiros, Pedro ;  University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Systems Ecology
Language :
Title :
Development of data integration tools within functional genomics
Defense date :
22 March 2022
Number of pages :
Institution :
Unilu - University of Luxembourg, Luxembourg
Degree :
PhD in Biology
President :
Jury member :
Finn, Rob
Rattei, Thomas
Focus Area :
Systems Biomedicine
Computational Sciences
Funders :
FNR - Fonds National de la Recherche [LU]
CER - Conseil Européen de la Recherche [BE]
Available on ORBilu :
since 06 April 2022


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