Article (Scientific journals)
The FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models.
PACHECO, Maria; SAUTER, Thomas
2018In Methods in Molecular Biology, (1716), p. 101-110
Peer reviewed
 

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Keywords :
Algorithm; Constraint-based modeling; Context-specific; FBA; Metabolic modeling; Microarray; omics data integration
Abstract :
[en] The FASTCORE family is a family of algorithms that are mainly used to build context-specific models but can also be applied to other tasks such as gapfilling and consistency testing. The FASTCORE family has very low computational demands with running times that are several orders of magnitude lower than its main competitors. Furthermore, the models built by the FASTCORE family have a better resolution power (defined as the ability to capture metabolic variations between different tissues, cell types, or contexts) than models from other algorithms.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
PACHECO, Maria 
SAUTER, Thomas ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit
External co-authors :
no
Language :
English
Title :
The FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models.
Publication date :
2018
Journal title :
Methods in Molecular Biology
ISSN :
1064-3745
Publisher :
Humana Press, Totowa, United States - New Jersey
Issue :
1716
Pages :
101-110
Peer reviewed :
Peer reviewed
Focus Area :
Systems Biomedicine
FnR Project :
FNR6041230 - Fast Reconstruction Of Context Specific Metabolic Network Models, 2013 (01/04/2013-31/10/2016) - Maria Irene Pires Pacheco
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since 07 March 2018

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