Profil

BRENNER Dirk

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Immunology and Genetics

ORCID
0000-0001-8979-1045
Main Referenced Co-authors
Mak, Tak W (9)
Dostert, Catherine (8)
Grusdat, Melanie (8)
Brüstle, Anne (6)
Franchina, Davide G (6)
Main Referenced Keywords
Animals (26); Humans (19); Mice (18); Immunology (12); Cell Biology (9);
Main Referenced Disciplines
Immunology & infectious disease (37)
Oncology (2)
Biochemistry, biophysics & molecular biology (2)
Neurology (1)
Genetics & genetic processes (1)

Publications (total 44)

The most downloaded
67 downloads
Blaser, H., Dostert, C., Mak, T. W., & BRENNER, D. (April 2016). TNF and ROS Crosstalk in Inflammation. Trends in Cell Biology, 26 (4), 249 - 261. doi:10.1016/j.tcb.2015.12.002 https://hdl.handle.net/10993/58029

The most cited

739 citations (Scopus®)

Blaser, H., Dostert, C., Mak, T. W., & BRENNER, D. (April 2016). TNF and ROS Crosstalk in Inflammation. Trends in Cell Biology, 26 (4), 249 - 261. doi:10.1016/j.tcb.2015.12.002 https://hdl.handle.net/10993/58029

The most significant

Wartewig, T., Daniels, J., Schulz, M., Hameister, E., Joshi, A., Park, J., Morrish, E., Venkatasubramani, A. V., Cernilogar, F. M., van Heijster, F. H. A., Hundshammer, C., Schneider, H., Konstantinidis, F., Gabler, J. V., Klement, C., KURNIAWAN, H., Law, C., Lee, Y., Choi, S., ... Ruland, J. (October 2023). PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature Cancer, 4 (10), 1508 - 1525. doi:10.1038/s43018-023-00635-7
Peer Reviewed verified by ORBi

Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y., ... BRENNER, D. (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58027. doi:10.1101/2023.07.06.547932

He, W., Henne, A., Lauterbach, M., Geißmar, E., Nikolka, F., Kho, C., Heinz, A., Dostert, C., Grusdat, M., Cordes, T., Härm, J., Goldmann, O., Ewen, A., Verschueren, C., Blay-Cadanet, J., Geffers, R., Garritsen, H., Kneiling, M., Holm, C. K., ... Hiller, K. (May 2022). Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages. Nature Metabolism, 4 (5), 524 - 533. doi:10.1038/s42255-022-00565-1
Peer Reviewed verified by ORBi

Franchina, D. G., Kurniawan, H., Grusdat, M., Binsfeld, C., Guerra, L., Bonetti, L., Soriano-Baguet, L., Ewen, A., Kobayashi, T., Farinelle, S., Minafra, A. R., Vandamme, N., Carpentier, A., Borgmann, F. K., Jäger, C., Chen, Y., Kleinewietfeld, M., Vasiliou, V., Mittelbronn, M., ... BRENNER, D. (04 April 2022). Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells. Nature Communications, 13 (1), 1789. doi:10.1038/s41467-022-29426-x
Peer Reviewed verified by ORBi

Kurniawan, H., Franchina, D. G., GUERRA, L., BONETTI, L., - Baguet, L. S., Grusdat, M., Schlicker, L., Hunewald, O., Dostert, C., Merz, M. P., Binsfeld, C., Duncan, G. S., FARINELLE, S., Nonnenmacher, Y., Haight, J., Das Gupta, D., Ewen, A., Taskesen, R., HALDER, R., ... BRENNER, D. (05 May 2020). Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism, 31 (5), 920--936.e7. doi:10.1016/j.cmet.2020.03.004
Peer reviewed


Wartewig, T., Daniels, J., Schulz, M., Hameister, E., Joshi, A., Park, J., Morrish, E., Venkatasubramani, A. V., Cernilogar, F. M., van Heijster, F. H. A., Hundshammer, C., Schneider, H., Konstantinidis, F., Gabler, J. V., Klement, C., KURNIAWAN, H., Law, C., Lee, Y., Choi, S., ... Ruland, J. (October 2023). PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature Cancer, 4 (10), 1508 - 1525. doi:10.1038/s43018-023-00635-7
Peer Reviewed verified by ORBi

Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y., ... BRENNER, D. (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58027. doi:10.1101/2023.07.06.547932

Cable, J., Rathmell, J. C., Pearce, E. L., Ho, P.-C., Haigis, M. C., Mamedov, M. R., Wu, M.-J., Kaech, S. M., Lynch, L., Febbraio, M. A., Bapat, S. P., Hong, H. S., Zou, W., Belkaid, Y., Sullivan, Z. A., Keller, A., Wculek, S. K., Green, D. R., Postic, C., ... BRENNER, D. (May 2023). Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report. Annals of the New York Academy of Sciences, 1523 (1), 38 - 50. doi:10.1111/nyas.14976
Peer Reviewed verified by ORBi

Soriano-Baguet, L., & BRENNER, D. (March 2023). Metabolism and epigenetics at the heart of T cell function. Trends in Immunology, 44 (3), 231 - 244. doi:10.1016/j.it.2023.01.002
Peer Reviewed verified by ORBi

Asantewaa, G., Tuttle, E. T., Ward, N. P., Kang, Y. P., Kim, Y., Kavanagh, M. E., Girnius, N., Chen, Y., Duncan, R., Rodriguez, K., Hecht, F., Zocchi, M., Smorodintsev-Schiller, L., Scales, T. Q., Taylor, K., Alimohammadi, F., Sechrist, Z. R., Agostini-Vulaj, D., Schafer, X. L., ... Harris, I. S. (2023). Glutathione supports lipid abundance in vivo. bioRxiv : the preprint server for biology. doi:10.1101/2023.02.10.524960

Côrte-Real, B. F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M. W., KURNIAWAN, H., Wagner, A., Yosef, N., Weiss, S. N. Y., Schmetterer, K. G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., ... Kleinewietfeld, M. (07 February 2023). Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs. Cell Metabolism, 35 (2), 299 - 315.e8. doi:10.1016/j.cmet.2023.01.009
Peer Reviewed verified by ORBi

Soriano-Baguet, S., BRENNER, D., LONGWORTH, J., & GRUSDAT-POZDEEV, M. (2023). Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions. Cell Reports, 42 (3).
Peer Reviewed verified by ORBi

Grusdat, M., Dostert, C., & BRENNER, D. (2023). Chapter 9 - Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers. In Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers (pp. 173, pages 121-131). Elsevier. doi:10.1016/bs.mcb.2022.03.003
Peer Reviewed verified by ORBi

Heinz, A., Nonnenmacher, Y., Henne, A., Khalil, M.-A., Bejkollari, K., Dostert, C., Hosseini, S., Goldmann, O., He, W., Palorini, R., Verschueren, C., Korte, M., Chiaradonna, F., Medina, E., BRENNER, D., & Hiller, K. (01 December 2022). Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1868 (12), 166530. doi:10.1016/j.bbadis.2022.166530
Peer Reviewed verified by ORBi

Danileviciute, E., Zeng, N., Capelle, C. M., Paczia, N., Gillespie, M. A., KURNIAWAN, H., Benzarti, M., Merz, M. P., COOWAR, D., Fritah, S., Vogt Weisenhorn, D. M., GOMEZ GIRO, G., GRUSDAT, M., BARON, A., Guerin, C., Franchina, D. G., Léonard, C., Domingues, O., Delhalle, S., ... HE, F. (26 May 2022). PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T(reg) homeostasis during ageing. Nature Metabolism, 4 (5), 589-607. doi:10.1038/s42255-022-00576-y
Peer Reviewed verified by ORBi

Kobayashi, T., & BRENNER, D. (03 May 2022). A FAsT contribution: Adipocytes rewire their metabolism to acquire immune functions. Cell Metabolism, 34 (5), 656 - 657. doi:10.1016/j.cmet.2022.04.007
Peer Reviewed verified by ORBi

He, W., Henne, A., Lauterbach, M., Geißmar, E., Nikolka, F., Kho, C., Heinz, A., Dostert, C., Grusdat, M., Cordes, T., Härm, J., Goldmann, O., Ewen, A., Verschueren, C., Blay-Cadanet, J., Geffers, R., Garritsen, H., Kneiling, M., Holm, C. K., ... Hiller, K. (May 2022). Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages. Nature Metabolism, 4 (5), 524 - 533. doi:10.1038/s42255-022-00565-1
Peer Reviewed verified by ORBi

Franchina, D. G., Kurniawan, H., Grusdat, M., Binsfeld, C., Guerra, L., Bonetti, L., Soriano-Baguet, L., Ewen, A., Kobayashi, T., Farinelle, S., Minafra, A. R., Vandamme, N., Carpentier, A., Borgmann, F. K., Jäger, C., Chen, Y., Kleinewietfeld, M., Vasiliou, V., Mittelbronn, M., ... BRENNER, D. (04 April 2022). Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells. Nature Communications, 13 (1), 1789. doi:10.1038/s41467-022-29426-x
Peer Reviewed verified by ORBi

Sipol, A., Hameister, E., Xue, B., Hofstetter, J., Barenboim, M., Öllinger, R., Jain, G., Prexler, C., Rubio, R. A., Baldauf, M. C., Franchina, D. G., Petry, A., Schmäh, J., Thiel, U., Görlach, A., Cario, G., BRENNER, D., Richter, G. H. S., Grünewald, T. G. P., ... Burdach, S. E. G. (24 February 2022). MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress. Blood, 139 (8), 1184 - 1197. doi:10.1182/blood.2020007932
Peer Reviewed verified by ORBi

Kiweler, N., Delbrouck, C., POZDEEV, V., Neises, L., Soriano-Bague, L., Eiden, K., Xian, F., Benzarti, M., Haase, L., KONCINA, E., SCHMOETTEN, M., JÄGER, C., Zaeem Noman, M., Vazquez, A., Janji, B., DITTMAR, G., BRENNER, D., LETELLIER, E., & Meiser, J. (2022). Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis. Nature Communications. doi:10.1038/s41467-022-30363-y
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Zeng, N.* , Capelle, C. M.* , BARON, A., KOBAYASHI, T., Cire, S., TSLAF, V., Leonard, C., COOWAR, D., Koseki, H., Westendorf, A. M., Buer, J., BRENNER, D., KRÜGER, R., Balling, R., OLLERT, M., & HE, F. (2022). DJ‐1 depletion prevents immunoaging in T‐cell compartments. EMBO Reports, 23 (3). doi:10.15252/embr.202153302
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* These authors have contributed equally to this work.

Yang, W., Denger, A., Diener, C., Küppers, F., Soriano-Baguet, L., Schäfer, G., Yanamandra, A. K., Zhao, R., Knörck, A., Schwarz, E. C., Hart, M., Lammert, F., Roma, L. P., BRENNER, D., Christidis, G., Helms, V., Meese, E., Hoth, M., & Qu, B. (2022). Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand. Frontiers in Immunology, 13, 831680. doi:10.3389/fimmu.2022.831680
Peer Reviewed verified by ORBi

Zeng, N., Capelle, C., Baron, A., Cire, S., Leonard, C., COOWAR, D., Koseki, H., Westendorf, A., Buer, J., BRENNER, D., KRÜGER, R., Balling, R., OLLERT, M., & HE, F. (2021). DJ-1 depletion slows down immunoaging in T-cell compartments. bioRxiv. doi:10.1101/2021.05.21.445139

Kurniawan, H., Kobayashi, T., & BRENNER, D. (April 2021). The emerging role of one-carbon metabolism in T cells. Current Opinion in Biotechnology, 68, 193 - 201. doi:10.1016/j.copbio.2020.12.001
Peer Reviewed verified by ORBi

Hiller, K., & BRENNER, D. (April 2021). Editorial overview: Intrinsically tied: metabolism and immune cell function. Current Opinion in Biotechnology, 68. doi:10.1016/j.copbio.2021.03.006
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Zhu, J., Yang, W., Zhou, X., Zöphel, D., Soriano-Baguet, L., Dolgener, D., Carlein, C., Hof, C., Zhao, R., Ye, S., Schwarz, E. C., BRENNER, D., Prates Roma, L., & Qu, B. (2021). High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity. Frontiers in Immunology, 12, 689337. doi:10.3389/fimmu.2021.689337
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Neumann, M., Steimle, A., Grant, E. T., Wolter, M., Parrish, A., Willieme, S., BRENNER, D., Martens, E. C., & Desai, M. S. (2021). Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium. Gut Microbes, 13 (1), 1966263. doi:10.1080/19490976.2021.1966263
Peer Reviewed verified by ORBi

Kurniawan, H., Soriano-Baguet, L., & BRENNER, D. (November 2020). Regulatory T cell metabolism at the intersection between autoimmune diseases and cancer. European Journal of Immunology, 50 (11), 1626 - 1642. doi:10.1002/eji.201948470
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Guerra, L., Bonetti, L., & BRENNER, D. (07 July 2020). Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy. Cell Reports, 32 (1), 107848. doi:10.1016/j.celrep.2020.107848
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Kurniawan, H., Franchina, D. G., GUERRA, L., BONETTI, L., - Baguet, L. S., Grusdat, M., Schlicker, L., Hunewald, O., Dostert, C., Merz, M. P., Binsfeld, C., Duncan, G. S., FARINELLE, S., Nonnenmacher, Y., Haight, J., Das Gupta, D., Ewen, A., Taskesen, R., HALDER, R., ... BRENNER, D. (05 May 2020). Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism, 31 (5), 920--936.e7. doi:10.1016/j.cmet.2020.03.004
Peer reviewed

Zhuang, Y., Xu, H. C., Shinde, P. V., Warfsmann, J., Vasilevska, J., Sundaram, B., Behnke, K., Huang, J., Hoell, J. I., Borkhardt, A., Pfeffer, K., Taha, M. S., Herebian, D., Mayatepek, E., BRENNER, D., Ahmadian, M. R., Keitel, V., Wieczorek, D., Häussinger, D., ... Lang, P. A. (January 2020). Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury. Gut, 69 (1), 133 - 145. doi:10.1136/gutjnl-2019-318215
Peer Reviewed verified by ORBi

Lückel, C., Picard, F., Raifer, H., Campos Carrascosa, L., Guralnik, A., Zhang, Y., Klein, M., Bittner, S., Steffen, F., Moos, S., Marini, F., Gloury, R., Kurschus, F. C., Chao, Y.-Y., Bertrams, W., Sexl, V., Schmeck, B., Bonetti, L., Grusdat, M., ... Huber, M. (16 December 2019). IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nature Communications, 10 (1), 5722. doi:10.1038/s41467-019-13731-z
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Cossarizza, A., Chang, H.-D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., ... Zychlinsky, A. (October 2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology, 49 (10), 1457 - 1973. doi:10.1002/eji.201970107
Peer Reviewed verified by ORBi

Wilson, A. S., Law, H. D., Knobbe-Thomsen, C. B., Kearney, C. J., Oliaro, J., Binsfeld, C., Burgio, G., Starrs, L., BRENNER, D., Randall, K. L., & Brüstle, A. (May 2019). Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery. European Journal of Immunology, 49 (5), 770 - 781. doi:10.1002/eji.201847960
Peer Reviewed verified by ORBi

Cox, M. A., Duncan, G. S., Lin, G. H. Y., Steinberg, B. E., Yu, L. X., BRENNER, D., Buckler, L. N., Elia, A. J., Wakeham, A. C., Nieman, B., Dominguez-Brauer, C., Elford, A. R., Gill, K. T., Kubli, S. P., Haight, J., Berger, T., Ohashi, P. S., Tracey, K. J., Olofsson, P. S., & Mak, T. W. (08 February 2019). Choline acetyltransferase-expressing T cells are required to control chronic viral infection. Science, 363 (6427), 639 - 644. doi:10.1126/science.aau9072
Peer Reviewed verified by ORBi

Franchina, D. G., Dostert, C., & BRENNER, D. (June 2018). Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism. Trends in Immunology, 39 (6), 489 - 502. doi:10.1016/j.it.2018.01.005
Peer Reviewed verified by ORBi

Shinde, P. V., Xu, H. C., Maney, S. K., Kloetgen, A., Namineni, S., Zhuang, Y., Honke, N., Shaabani, N., Bellora, N., Doerrenberg, M., Trilling, M., Pozdeev, V. I., van Rooijen, N., Scheu, S., Pfeffer, K., Crocker, P. R., Tanaka, M., Duggimpudi, S., Knolle, P., ... Lang, P. A. (01 February 2018). Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection. Journal of Virology, 92 (3). doi:10.1128/JVI.01637-17
Peer Reviewed verified by ORBi

Franchina, D. G., Grusdat, M., & BRENNER, D. (February 2018). B-Cell Metabolic Remodeling and Cancer. Trends in Cancer, 4 (2), 138 - 150. doi:10.1016/j.trecan.2017.12.006
Peer Reviewed verified by ORBi

Franchina, D. G., He, F., & BRENNER, D. (01 January 2018). Survival of the fittest: Cancer challenges T cell metabolism. Cancer Letters, 412, 216 - 223. doi:10.1016/j.canlet.2017.10.014
Peer Reviewed verified by ORBi

Brüstle, A., BRENNER, D., Knobbe-Thomsen, C. B., Cox, M., Lang, P. A., Lang, K. S., & Mak, T. W. (July 2017). MALT1 is an intrinsic regulator of regulatory T cells. Cell Death and Differentiation, 24 (7), 1214 - 1223. doi:10.1038/cdd.2015.104
Peer Reviewed verified by ORBi

Mak, T. W., Grusdat, M., Duncan, G. S., Dostert, C., Nonnenmacher, Y., Cox, M., Binsfeld, C., Hao, Z., Brüstle, A., Itsumi, M., Jäger, C., Chen, Y., Pinkenburg, O., Camara, B., Ollert, M., Bindslev-Jensen, C., Vasiliou, V., Gorrini, C., Lang, P. A., ... BRENNER, D. (20 June 2017). Glutathione Primes T Cell Metabolism for Inflammation. Immunity, 46 (6), 1089 - 1090. doi:10.1016/j.immuni.2017.06.009
Peer Reviewed verified by ORBi

Hao, Z., Sheng, Y., Duncan, G. S., Li, W. Y., Dominguez, C., Sylvester, J., Su, Y.-W., Lin, G. H. Y., Snow, B. E., BRENNER, D., You-Ten, A., Haight, J., Inoue, S., Wakeham, A., Elford, A., Hamilton, S., Liang, Y., Zúñiga-Pflücker, J. C., He, H. H., ... Mak, T. W. (13 January 2017). K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Nature Communications, 8 (1), 14003. doi:10.1038/ncomms14003
Peer Reviewed verified by ORBi

Blaser, H., Dostert, C., Mak, T. W., & BRENNER, D. (April 2016). TNF and ROS Crosstalk in Inflammation. Trends in Cell Biology, 26 (4), 249 - 261. doi:10.1016/j.tcb.2015.12.002
Peer Reviewed verified by ORBi

Itsumi, M., Inoue, S., Elia, A. J., Murakami, K., Sasaki, M., Lind, E. F., BRENNER, D., Harris, I. S., Chio, I. I. C., Afzal, S., Cairns, R. A., Cescon, D. W., Elford, A. R., Ye, J., Lang, P. A., Li, W. Y., Wakeham, A., Duncan, G. S., Haight, J., ... Mak, T. W. (November 2015). Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio. Cell Death and Differentiation, 22 (11), 1837 - 1845. doi:10.1038/cdd.2015.38
Peer Reviewed verified by ORBi

Bothur, E., Raifer, H., Haftmann, C., Stittrich, A.-B., Brüstle, A., BRENNER, D., Bollig, N., Bieringer, M., Kang, C.-H., Reinhard, K., Camara, B., Huber, M., Visekruna, A., Steinhoff, U., Repenning, A., Bauer, U.-M., Sexl, V., Radbruch, A., Sparwasser, T., ... Lohoff, M. (13 October 2015). Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. Nature Communications, 6 (1), 8576. doi:10.1038/ncomms9576
Peer Reviewed verified by ORBi

BRENNER, D., Blaser, H., & Mak, T. W. (June 2015). Regulation of tumour necrosis factor signalling: live or let die. Nature Reviews. Immunology, 15 (6), 362 - 374. doi:10.1038/nri3834
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Bornancin, F., Renner, F., Touil, R., Sic, H., Kolb, Y., Touil-Allaoui, I., Rush, J. S., Smith, P. A., Bigaud, M., Junker-Walker, U., Burkhart, C., Dawson, J., Niwa, S., Katopodis, A., Nuesslein-Hildesheim, B., Weckbecker, G., Zenke, G., Kinzel, B., Traggiai, E., ... Calzascia, T. (15 April 2015). Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. Journal of Immunology, 194 (8), 3723 - 3734. doi:10.4049/jimmunol.1402254
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Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., BRENNER, D., Knobbe-Thomsen, C. B., Cox, M. A., Elia, A., Berger, T., Cescon, D. W., Adeoye, A., Brüstle, A., Molyneux, S. D., Mason, J. M., Li, W. Y., Yamamoto, K., ... Mak, T. W. (09 February 2015). Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell, 27 (2), 211 - 222. doi:10.1016/j.ccell.2014.11.019
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Afzal, S., Hao, Z., Itsumi, M., Abouelkheer, Y., BRENNER, D., Gao, Y., Wakeham, A., Hong, C., Li, W. Y., Sylvester, J., Gilani, S. O., Brüstle, A., Haight, J., You-Ten, A. J., Lin, G. H. Y., Inoue, S., & Mak, T. W. (27 January 2015). Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 112 (4), 1119 - 1124. doi:10.1073/pnas.1423588112
Peer Reviewed verified by ORBi

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