![]() ![]() | Wartewig, T., Daniels, J., Schulz, M., Hameister, E., Joshi, A., Park, J., Morrish, E., Venkatasubramani, A. V., Cernilogar, F. M., van Heijster, F. H. A., Hundshammer, C., Schneider, H., Konstantinidis, F., Gabler, J. V., Klement, C., KURNIAWAN, H., Law, C., Lee, Y., Choi, S., ... Ruland, J. (October 2023). PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature Cancer, 4 (10), 1508 - 1525. doi:10.1038/s43018-023-00635-7 ![]() |
![]() ![]() | Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y., ... BRENNER, D. (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58027. doi:10.1101/2023.07.06.547932 |
![]() ![]() | He, W., Henne, A., Lauterbach, M., Geißmar, E., Nikolka, F., Kho, C., Heinz, A., Dostert, C., Grusdat, M., Cordes, T., Härm, J., Goldmann, O., Ewen, A., Verschueren, C., Blay-Cadanet, J., Geffers, R., Garritsen, H., Kneiling, M., Holm, C. K., ... Hiller, K. (May 2022). Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages. Nature Metabolism, 4 (5), 524 - 533. doi:10.1038/s42255-022-00565-1 ![]() |
![]() ![]() | Franchina, D. G., Kurniawan, H., Grusdat, M., Binsfeld, C., Guerra, L., Bonetti, L., Soriano-Baguet, L., Ewen, A., Kobayashi, T., Farinelle, S., Minafra, A. R., Vandamme, N., Carpentier, A., Borgmann, F. K., Jäger, C., Chen, Y., Kleinewietfeld, M., Vasiliou, V., Mittelbronn, M., ... BRENNER, D. (04 April 2022). Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells. Nature Communications, 13 (1), 1789. doi:10.1038/s41467-022-29426-x ![]() |
![]() ![]() | Kurniawan, H., Franchina, D. G., GUERRA, L., BONETTI, L., - Baguet, L. S., Grusdat, M., Schlicker, L., Hunewald, O., Dostert, C., Merz, M. P., Binsfeld, C., Duncan, G. S., FARINELLE, S., Nonnenmacher, Y., Haight, J., Das Gupta, D., Ewen, A., Taskesen, R., HALDER, R., ... BRENNER, D. (05 May 2020). Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism, 31 (5), 920--936.e7. doi:10.1016/j.cmet.2020.03.004 ![]() |
![]() ![]() | Wartewig, T., Daniels, J., Schulz, M., Hameister, E., Joshi, A., Park, J., Morrish, E., Venkatasubramani, A. V., Cernilogar, F. M., van Heijster, F. H. A., Hundshammer, C., Schneider, H., Konstantinidis, F., Gabler, J. V., Klement, C., KURNIAWAN, H., Law, C., Lee, Y., Choi, S., ... Ruland, J. (October 2023). PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature Cancer, 4 (10), 1508 - 1525. doi:10.1038/s43018-023-00635-7 ![]() |
![]() ![]() | Bonetti, L., Horkova, V., Longworth, J., Guerra, L., Kurniawan, H., Franchina, D. G., Soriano-Baguet, L., Grusdat, M., Spath, S., Koncina, E., Ewen, A., Binsfeld, C., Verschueren, C., Gérardy, J.-J., Kobayashi, T., Dostert, C., Farinelle, S., Härm, J., Chen, Y., ... BRENNER, D. (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/58027. doi:10.1101/2023.07.06.547932 |
![]() ![]() | Cable, J., Rathmell, J. C., Pearce, E. L., Ho, P.-C., Haigis, M. C., Mamedov, M. R., Wu, M.-J., Kaech, S. M., Lynch, L., Febbraio, M. A., Bapat, S. P., Hong, H. S., Zou, W., Belkaid, Y., Sullivan, Z. A., Keller, A., Wculek, S. K., Green, D. R., Postic, C., ... BRENNER, D. (May 2023). Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report. Annals of the New York Academy of Sciences, 1523 (1), 38 - 50. doi:10.1111/nyas.14976 ![]() |
![]() ![]() | Soriano-Baguet, L., & BRENNER, D. (March 2023). Metabolism and epigenetics at the heart of T cell function. Trends in Immunology, 44 (3), 231 - 244. doi:10.1016/j.it.2023.01.002 ![]() |
Asantewaa, G., Tuttle, E. T., Ward, N. P., Kang, Y. P., Kim, Y., Kavanagh, M. E., Girnius, N., Chen, Y., Duncan, R., Rodriguez, K., Hecht, F., Zocchi, M., Smorodintsev-Schiller, L., Scales, T. Q., Taylor, K., Alimohammadi, F., Sechrist, Z. R., Agostini-Vulaj, D., Schafer, X. L., ... Harris, I. S. (2023). Glutathione supports lipid abundance in vivo. bioRxiv : the preprint server for biology. doi:10.1101/2023.02.10.524960 |
![]() ![]() | Côrte-Real, B. F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M. W., KURNIAWAN, H., Wagner, A., Yosef, N., Weiss, S. N. Y., Schmetterer, K. G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., ... Kleinewietfeld, M. (07 February 2023). Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs. Cell Metabolism, 35 (2), 299 - 315.e8. doi:10.1016/j.cmet.2023.01.009 ![]() |
![]() ![]() | Soriano-Baguet, S., BRENNER, D., LONGWORTH, J., & GRUSDAT-POZDEEV, M. (2023). Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions. Cell Reports, 42 (3). ![]() |
Grusdat, M., Dostert, C., & BRENNER, D. (2023). Chapter 9 - Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers. In Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers (pp. 173, pages 121-131). Elsevier. doi:10.1016/bs.mcb.2022.03.003 ![]() |
![]() ![]() | Heinz, A., Nonnenmacher, Y., Henne, A., Khalil, M.-A., Bejkollari, K., Dostert, C., Hosseini, S., Goldmann, O., He, W., Palorini, R., Verschueren, C., Korte, M., Chiaradonna, F., Medina, E., BRENNER, D., & Hiller, K. (01 December 2022). Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1868 (12), 166530. doi:10.1016/j.bbadis.2022.166530 ![]() |
![]() ![]() | Danileviciute, E., Zeng, N., Capelle, C. M., Paczia, N., Gillespie, M. A., KURNIAWAN, H., Benzarti, M., Merz, M. P., COOWAR, D., Fritah, S., Vogt Weisenhorn, D. M., GOMEZ GIRO, G., GRUSDAT, M., BARON, A., Guerin, C., Franchina, D. G., Léonard, C., Domingues, O., Delhalle, S., ... HE, F. (26 May 2022). PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T(reg) homeostasis during ageing. Nature Metabolism, 4 (5), 589-607. doi:10.1038/s42255-022-00576-y ![]() |
![]() ![]() | Kobayashi, T., & BRENNER, D. (03 May 2022). A FAsT contribution: Adipocytes rewire their metabolism to acquire immune functions. Cell Metabolism, 34 (5), 656 - 657. doi:10.1016/j.cmet.2022.04.007 ![]() |
![]() ![]() | He, W., Henne, A., Lauterbach, M., Geißmar, E., Nikolka, F., Kho, C., Heinz, A., Dostert, C., Grusdat, M., Cordes, T., Härm, J., Goldmann, O., Ewen, A., Verschueren, C., Blay-Cadanet, J., Geffers, R., Garritsen, H., Kneiling, M., Holm, C. K., ... Hiller, K. (May 2022). Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages. Nature Metabolism, 4 (5), 524 - 533. doi:10.1038/s42255-022-00565-1 ![]() |
![]() ![]() | Franchina, D. G., Kurniawan, H., Grusdat, M., Binsfeld, C., Guerra, L., Bonetti, L., Soriano-Baguet, L., Ewen, A., Kobayashi, T., Farinelle, S., Minafra, A. R., Vandamme, N., Carpentier, A., Borgmann, F. K., Jäger, C., Chen, Y., Kleinewietfeld, M., Vasiliou, V., Mittelbronn, M., ... BRENNER, D. (04 April 2022). Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells. Nature Communications, 13 (1), 1789. doi:10.1038/s41467-022-29426-x ![]() |
![]() ![]() | Sipol, A., Hameister, E., Xue, B., Hofstetter, J., Barenboim, M., Öllinger, R., Jain, G., Prexler, C., Rubio, R. A., Baldauf, M. C., Franchina, D. G., Petry, A., Schmäh, J., Thiel, U., Görlach, A., Cario, G., BRENNER, D., Richter, G. H. S., Grünewald, T. G. P., ... Burdach, S. E. G. (24 February 2022). MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress. Blood, 139 (8), 1184 - 1197. doi:10.1182/blood.2020007932 ![]() |
![]() ![]() | Yang, W., Denger, A., Diener, C., Küppers, F., Soriano-Baguet, L., Schäfer, G., Yanamandra, A. K., Zhao, R., Knörck, A., Schwarz, E. C., Hart, M., Lammert, F., Roma, L. P., BRENNER, D., Christidis, G., Helms, V., Meese, E., Hoth, M., & Qu, B. (2022). Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand. Frontiers in Immunology, 13, 831680. doi:10.3389/fimmu.2022.831680 ![]() |
![]() ![]() | Zeng, N.* , Capelle, C. M.* , BARON, A., KOBAYASHI, T., Cire, S., TSLAF, V., Leonard, C., COOWAR, D., Koseki, H., Westendorf, A. M., Buer, J., BRENNER, D., KRÜGER, R., Balling, R., OLLERT, M., & HE, F. (2022). DJ‐1 depletion prevents immunoaging in T‐cell compartments. EMBO Reports, 23 (3). doi:10.15252/embr.202153302 ![]() * These authors have contributed equally to this work. |
![]() ![]() | Kiweler, N., Delbrouck, C., POZDEEV, V., Neises, L., Soriano-Bague, L., Eiden, K., Xian, F., Benzarti, M., Haase, L., KONCINA, E., SCHMOETTEN, M., JÄGER, C., Zaeem Noman, M., Vazquez, A., Janji, B., DITTMAR, G., BRENNER, D., LETELLIER, E., & Meiser, J. (2022). Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis. Nature Communications. doi:10.1038/s41467-022-30363-y ![]() |
![]() ![]() | Zeng, N., Capelle, C., Baron, A., Cire, S., Leonard, C., COOWAR, D., Koseki, H., Westendorf, A., Buer, J., BRENNER, D., KRÜGER, R., Balling, R., OLLERT, M., & HE, F. (2021). DJ-1 depletion slows down immunoaging in T-cell compartments. bioRxiv. doi:10.1101/2021.05.21.445139https://orbilu.uni.lu/handle/10993/50270 |
![]() ![]() | Hiller, K., & BRENNER, D. (April 2021). Editorial overview: Intrinsically tied: metabolism and immune cell function. Current Opinion in Biotechnology, 68. doi:10.1016/j.copbio.2021.03.006 ![]() |
![]() ![]() | Kurniawan, H., Kobayashi, T., & BRENNER, D. (April 2021). The emerging role of one-carbon metabolism in T cells. Current Opinion in Biotechnology, 68, 193 - 201. doi:10.1016/j.copbio.2020.12.001 ![]() |
![]() ![]() | Neumann, M., Steimle, A., Grant, E. T., Wolter, M., Parrish, A., Willieme, S., BRENNER, D., Martens, E. C., & Desai, M. S. (2021). Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium. Gut Microbes, 13 (1), 1966263. doi:10.1080/19490976.2021.1966263 ![]() |
![]() ![]() | Zhu, J., Yang, W., Zhou, X., Zöphel, D., Soriano-Baguet, L., Dolgener, D., Carlein, C., Hof, C., Zhao, R., Ye, S., Schwarz, E. C., BRENNER, D., Prates Roma, L., & Qu, B. (2021). High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity. Frontiers in Immunology, 12, 689337. doi:10.3389/fimmu.2021.689337 ![]() |
![]() ![]() | Kurniawan, H., Soriano-Baguet, L., & BRENNER, D. (November 2020). Regulatory T cell metabolism at the intersection between autoimmune diseases and cancer. European Journal of Immunology, 50 (11), 1626 - 1642. doi:10.1002/eji.201948470 ![]() |
![]() ![]() | Guerra, L., Bonetti, L., & BRENNER, D. (07 July 2020). Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy. Cell Reports, 32 (1), 107848. doi:10.1016/j.celrep.2020.107848 ![]() |
![]() ![]() | Kurniawan, H., Franchina, D. G., GUERRA, L., BONETTI, L., - Baguet, L. S., Grusdat, M., Schlicker, L., Hunewald, O., Dostert, C., Merz, M. P., Binsfeld, C., Duncan, G. S., FARINELLE, S., Nonnenmacher, Y., Haight, J., Das Gupta, D., Ewen, A., Taskesen, R., HALDER, R., ... BRENNER, D. (05 May 2020). Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism, 31 (5), 920--936.e7. doi:10.1016/j.cmet.2020.03.004 ![]() |
![]() ![]() | Zhuang, Y., Xu, H. C., Shinde, P. V., Warfsmann, J., Vasilevska, J., Sundaram, B., Behnke, K., Huang, J., Hoell, J. I., Borkhardt, A., Pfeffer, K., Taha, M. S., Herebian, D., Mayatepek, E., BRENNER, D., Ahmadian, M. R., Keitel, V., Wieczorek, D., Häussinger, D., ... Lang, P. A. (January 2020). Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury. Gut, 69 (1), 133 - 145. doi:10.1136/gutjnl-2019-318215 ![]() |
![]() ![]() | Lückel, C., Picard, F., Raifer, H., Campos Carrascosa, L., Guralnik, A., Zhang, Y., Klein, M., Bittner, S., Steffen, F., Moos, S., Marini, F., Gloury, R., Kurschus, F. C., Chao, Y.-Y., Bertrams, W., Sexl, V., Schmeck, B., Bonetti, L., Grusdat, M., ... Huber, M. (16 December 2019). IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nature Communications, 10 (1), 5722. doi:10.1038/s41467-019-13731-z ![]() |
![]() ![]() | Cossarizza, A., Chang, H.-D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., ... Zychlinsky, A. (October 2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology, 49 (10), 1457 - 1973. doi:10.1002/eji.201970107 ![]() ![]() |
![]() ![]() | Wilson, A. S., Law, H. D., Knobbe-Thomsen, C. B., Kearney, C. J., Oliaro, J., Binsfeld, C., Burgio, G., Starrs, L., BRENNER, D., Randall, K. L., & Brüstle, A. (May 2019). Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery. European Journal of Immunology, 49 (5), 770 - 781. doi:10.1002/eji.201847960 ![]() |
![]() ![]() | Cox, M. A., Duncan, G. S., Lin, G. H. Y., Steinberg, B. E., Yu, L. X., BRENNER, D., Buckler, L. N., Elia, A. J., Wakeham, A. C., Nieman, B., Dominguez-Brauer, C., Elford, A. R., Gill, K. T., Kubli, S. P., Haight, J., Berger, T., Ohashi, P. S., Tracey, K. J., Olofsson, P. S., & Mak, T. W. (08 February 2019). Choline acetyltransferase-expressing T cells are required to control chronic viral infection. Science, 363 (6427), 639 - 644. doi:10.1126/science.aau9072 ![]() |
![]() ![]() | Franchina, D. G., Dostert, C., & BRENNER, D. (June 2018). Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism. Trends in Immunology, 39 (6), 489 - 502. doi:10.1016/j.it.2018.01.005 ![]() |
![]() ![]() | Shinde, P. V., Xu, H. C., Maney, S. K., Kloetgen, A., Namineni, S., Zhuang, Y., Honke, N., Shaabani, N., Bellora, N., Doerrenberg, M., Trilling, M., Pozdeev, V. I., van Rooijen, N., Scheu, S., Pfeffer, K., Crocker, P. R., Tanaka, M., Duggimpudi, S., Knolle, P., ... Lang, P. A. (01 February 2018). Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection. Journal of Virology, 92 (3). doi:10.1128/JVI.01637-17 ![]() |
![]() ![]() | Franchina, D. G., Grusdat, M., & BRENNER, D. (February 2018). B-Cell Metabolic Remodeling and Cancer. Trends in Cancer, 4 (2), 138 - 150. doi:10.1016/j.trecan.2017.12.006 ![]() |
![]() ![]() | Franchina, D. G., He, F., & BRENNER, D. (01 January 2018). Survival of the fittest: Cancer challenges T cell metabolism. Cancer Letters, 412, 216 - 223. doi:10.1016/j.canlet.2017.10.014 ![]() |
![]() ![]() | Brüstle, A., BRENNER, D., Knobbe-Thomsen, C. B., Cox, M., Lang, P. A., Lang, K. S., & Mak, T. W. (July 2017). MALT1 is an intrinsic regulator of regulatory T cells. Cell Death and Differentiation, 24 (7), 1214 - 1223. doi:10.1038/cdd.2015.104 ![]() |
![]() ![]() | Mak, T. W., Grusdat, M., Duncan, G. S., Dostert, C., Nonnenmacher, Y., Cox, M., Binsfeld, C., Hao, Z., Brüstle, A., Itsumi, M., Jäger, C., Chen, Y., Pinkenburg, O., Camara, B., Ollert, M., Bindslev-Jensen, C., Vasiliou, V., Gorrini, C., Lang, P. A., ... BRENNER, D. (20 June 2017). Glutathione Primes T Cell Metabolism for Inflammation. Immunity, 46 (6), 1089 - 1090. doi:10.1016/j.immuni.2017.06.009 ![]() |
![]() ![]() | Hao, Z., Sheng, Y., Duncan, G. S., Li, W. Y., Dominguez, C., Sylvester, J., Su, Y.-W., Lin, G. H. Y., Snow, B. E., BRENNER, D., You-Ten, A., Haight, J., Inoue, S., Wakeham, A., Elford, A., Hamilton, S., Liang, Y., Zúñiga-Pflücker, J. C., He, H. H., ... Mak, T. W. (13 January 2017). K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Nature Communications, 8 (1), 14003. doi:10.1038/ncomms14003 ![]() |
![]() ![]() | Blaser, H., Dostert, C., Mak, T. W., & BRENNER, D. (April 2016). TNF and ROS Crosstalk in Inflammation. Trends in Cell Biology, 26 (4), 249 - 261. doi:10.1016/j.tcb.2015.12.002 ![]() |
![]() ![]() | Itsumi, M., Inoue, S., Elia, A. J., Murakami, K., Sasaki, M., Lind, E. F., BRENNER, D., Harris, I. S., Chio, I. I. C., Afzal, S., Cairns, R. A., Cescon, D. W., Elford, A. R., Ye, J., Lang, P. A., Li, W. Y., Wakeham, A., Duncan, G. S., Haight, J., ... Mak, T. W. (November 2015). Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio. Cell Death and Differentiation, 22 (11), 1837 - 1845. doi:10.1038/cdd.2015.38 ![]() |
![]() ![]() | Bothur, E., Raifer, H., Haftmann, C., Stittrich, A.-B., Brüstle, A., BRENNER, D., Bollig, N., Bieringer, M., Kang, C.-H., Reinhard, K., Camara, B., Huber, M., Visekruna, A., Steinhoff, U., Repenning, A., Bauer, U.-M., Sexl, V., Radbruch, A., Sparwasser, T., ... Lohoff, M. (13 October 2015). Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. Nature Communications, 6 (1), 8576. doi:10.1038/ncomms9576 ![]() |
![]() ![]() | BRENNER, D., Blaser, H., & Mak, T. W. (June 2015). Regulation of tumour necrosis factor signalling: live or let die. Nature Reviews. Immunology, 15 (6), 362 - 374. doi:10.1038/nri3834 ![]() |
![]() ![]() | Bornancin, F., Renner, F., Touil, R., Sic, H., Kolb, Y., Touil-Allaoui, I., Rush, J. S., Smith, P. A., Bigaud, M., Junker-Walker, U., Burkhart, C., Dawson, J., Niwa, S., Katopodis, A., Nuesslein-Hildesheim, B., Weckbecker, G., Zenke, G., Kinzel, B., Traggiai, E., ... Calzascia, T. (15 April 2015). Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. Journal of Immunology, 194 (8), 3723 - 3734. doi:10.4049/jimmunol.1402254 ![]() |
![]() ![]() | Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., BRENNER, D., Knobbe-Thomsen, C. B., Cox, M. A., Elia, A., Berger, T., Cescon, D. W., Adeoye, A., Brüstle, A., Molyneux, S. D., Mason, J. M., Li, W. Y., Yamamoto, K., ... Mak, T. W. (09 February 2015). Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell, 27 (2), 211 - 222. doi:10.1016/j.ccell.2014.11.019 ![]() |
![]() ![]() | Afzal, S., Hao, Z., Itsumi, M., Abouelkheer, Y., BRENNER, D., Gao, Y., Wakeham, A., Hong, C., Li, W. Y., Sylvester, J., Gilani, S. O., Brüstle, A., Haight, J., You-Ten, A. J., Lin, G. H. Y., Inoue, S., & Mak, T. W. (27 January 2015). Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 112 (4), 1119 - 1124. doi:10.1073/pnas.1423588112 ![]() |