KLEE, M., AHO, V., MAY, P., Heintz-Buschart, A., LANDOULSI, Z., JONSDOTTIR, S., PAULY, C., PAVELKA, L., DELACOUR, L., KAYSEN, A., Krüger, R., WILMES, P., LEIST, A., Acharya, G., Aguayo, G., Alexandre, M., ALI, M., Ammerlann, W., ARENA, G., ... ZELIMKHANOV, G. (2024). Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome. Journal of Prevention of Alzheimer's Disease. doi:10.14283/jpad.2024.19 Peer reviewed |
NOOR, F., Biemann, R., ROOMP, K., SCHNEIDER, J., & Isermann, B. (20 October 2020). Gene expression profile of CD14+ blood monocytes following lifestyle-induced weight loss in individuals with metabolic syndrome. Scientific Reports, 10 (1), 17855. doi:10.1038/s41598-020-74973-2 Peer Reviewed verified by ORBi |
Kraemer, M., Krawczyk, M., NOOR, F., Grunhage, F., Lammert, F., & SCHNEIDER, J. (2019). Increased Circulating VAP-1 Levels Are Associated with Liver Fibrosis in Chronic Hepatitis C Infection. Journal of Clinical Medicine, 8 (1). doi:10.3390/jcm8010103 Peer Reviewed verified by ORBi |
NOOR, F., KAYSEN, A., WILMES, P., & SCHNEIDER, J. (2018). The Gut Microbiota and Hematopoietic Stem Cell Transplantation: Challenges and Potentials. Journal of Innate Immunity, 1-11. doi:10.1159/000492943 Peer Reviewed verified by ORBi |
Weltin, A., Hammer, S., NOOR, F., Kaminski, Y., Kieninger, J., & Urban, G. A. (2017). Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Biosensors and Bioelectronics, 87, 941-948. doi:10.1016/j.bios.2016.07.094 Peer Reviewed verified by ORBi |
Langley, G. R., Adcock, I. M., Busquet, F., Crofton, K. M., Csernok, E., Giese, C., Heinonen, T., Herrmann, K., Hofmann-Apitius, M., Landesmann, B., Marshall, L. J., McIvor, E., Muotri, A. R., NOOR, F., Schutte, K., Seidle, T., van de Stolpe, A., Van Esch, H., Willett, C., & Woszczek, G. (2017). Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations. Drug Discovery Today, 22 (2), 327-339. doi:10.1016/j.drudis.2016.10.011 Peer Reviewed verified by ORBi |
Orsini, M., Sperber, S., NOOR, F., Hoffmann, E., Weber, S. N., Hall, R. A., Lammert, F., & Heinzle, E. (2017). Proteomic Characterization of Primary Mouse Hepatocytes in Collagen Monolayer and Sandwich Culture. Journal of Cellular Biochemistry. doi:10.1002/jcb.26202 Peer Reviewed verified by ORBi |
Garg, R., Heinzle, E., & NOOR, F. (2017). Hepatocytes of Wistar and Sprague Dawley rats differ significantly in their central metabolism. Journal of Cellular Biochemistry. doi:10.1002/jcb.26255 Peer Reviewed verified by ORBi |
Leite, S. B., Roosens, T., El Taghdouini, A., Mannaerts, I., Smout, A. J., Najimi, M., Sokal, E., NOOR, F., Chesne, C., & van Grunsven, L. A. (2016). Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro. Biomaterials, 78, 1-10. doi:10.1016/j.biomaterials.2015.11.026 Peer Reviewed verified by ORBi |
Priesnitz, C., Sperber, S., Garg, R., Orsini, M., & NOOR, F. (2016). Fluorescence based cell counting in collagen monolayer cultures of primary hepatocytes. Cytotechnology, 68 (4), 1647-53. doi:10.1007/s10616-014-9821-1 Peer reviewed |
Klein, S., Maggioni, S., Bucher, J., Mueller, D., Niklas, J., Shevchenko, V., Mauch, K., Heinzle, E., & NOOR, F. (2016). In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies. Toxicological sciences : an official journal of the Society of Toxicology, 149 (1), 55-66. doi:10.1093/toxsci/kfv218 Peer reviewed |
Richter, L. H. J., Kaminski, Y. R., NOOR, F., Meyer, M. R., & Maurer, H. H. (2016). Metabolic fate of desomorphine elucidated using rat urine, pooled human liver preparations, and human hepatocyte cultures as well as its detectability using standard urine screening approaches. Analytical and Bioanalytical Chemistry, 408 (23), 6283-94. doi:10.1007/s00216-016-9740-4 Peer Reviewed verified by ORBi |
NOOR, F. (2015). A shift in paradigm towards human biology-based systems for cholestatic-liver diseases. The Journal of physiology, 593 (23), 5043-55. doi:10.1113/JP271124 Peer reviewed |
Alepee, N., Bahinski, A., Daneshian, M., De Wever, B., Fritsche, E., Goldberg, A., Hansmann, J., Hartung, T., Haycock, J., Hogberg, H., Hoelting, L., Kelm, J. M., Kadereit, S., McVey, E., Landsiedel, R., Leist, M., Lubberstedt, M., NOOR, F., Pellevoisin, C., ... Zurich, M.-G. (2014). State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. ALTEX: Alternativen zu Tierexperimenten, 31 (4), 441-77. doi:10.14573/altex1406111 Peer reviewed |
Klein, S., Mueller, D., Schevchenko, V., & NOOR, F. (2014). Long-term maintenance of HepaRG cells in serum-free conditions and application in a repeated dose study. Journal of Applied Toxicology, 34 (10), 1078-86. doi:10.1002/jat.2929 Peer Reviewed verified by ORBi |
Mueller, D., Kramer, L., Hoffmann, E., Klein, S., & NOOR, F. (2014). 3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies. Toxicology in vitro : an international journal published in association with BIBRA, 28 (1), 104-12. doi:10.1016/j.tiv.2013.06.024 Peer reviewed |
Ramirez, T., Daneshian, M., Kamp, H., Bois, F. Y., Clench, M. R., Coen, M., Donley, B., Fischer, S. M., Ekman, D. R., Fabian, E., Guillou, C., Heuer, J., Hogberg, H. T., Jungnickel, H., Keun, H. C., Krennrich, G., Krupp, E., Luch, A., NOOR, F., ... Leist, M. (2013). Metabolomics in toxicology and preclinical research. ALTEX: Alternativen zu Tierexperimenten, 30 (2), 209-25. doi:10.14573/altex.2013.2.209 Peer reviewed |
Gunness, P., Mueller, D., Shevchenko, V., Heinzle, E., Ingelman-Sundberg, M., & NOOR, F. (2013). 3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies. Toxicological sciences : an official journal of the Society of Toxicology, 133 (1), 67-78. doi:10.1093/toxsci/kft021 Peer reviewed |
Mueller, D., Tascher, G., Damm, G., Nussler, A. K., Heinzle, E., & NOOR, F. (2013). Real-time in situ viability assessment in a 3D bioreactor with liver cells using resazurin assay. Cytotechnology, 65 (2), 297-305. doi:10.1007/s10616-012-9486-6 Peer reviewed |
Strigun, A., Wahrheit, J., Niklas, J., Heinzle, E., & NOOR, F. (2012). Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis. Toxicological sciences : an official journal of the Society of Toxicology, 125 (2), 595-606. doi:10.1093/toxsci/kfr298 Peer reviewed |
Mueller, D., Muller-Vieira, U., Biemel, K. M., Tascher, G., Nussler, A. K., & NOOR, F. (2012). Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure. European Journal of Pharmaceutical Sciences, 45 (5), 716-24. doi:10.1016/j.ejps.2012.01.014 Peer Reviewed verified by ORBi |
Mandenius, C.-F., Steel, D., NOOR, F., Meyer, T., Heinzle, E., Asp, J., Arain, S., Kraushaar, U., Bremer, S., Class, R., & Sartipy, P. (2011). Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review. Journal of Applied Toxicology, 31 (3), 191-205. doi:10.1002/jat.1663 Peer Reviewed verified by ORBi |
Mandenius, C.-F., Andersson, T. B., Alves, P. M., Batzl-Hartmann, C., Bjorquist, P., Carrondo, M. J. T., Chesne, C., Coecke, S., Edsbagge, J., Fredriksson, J. M., Gerlach, J. C., Heinzle, E., Ingelman-Sundberg, M., Johansson, I., Kuppers-Munther, B., Muller-Vieira, U., NOOR, F., & Zeilinger, K. (2011). Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project. Alternatives to laboratory animals : ATLA, 39 (2), 147-71. doi:10.1177/026119291103900210 Peer reviewed |
Strigun, A., NOOR, F., Pironti, A., Niklas, J., Yang, T. H., & Heinzle, E. (2011). Metabolic flux analysis gives an insight on verapamil induced changes in central metabolism of HL-1 cells. Journal of Biotechnology, 155 (3), 299-307. doi:10.1016/j.jbiotec.2011.07.028 Peer Reviewed verified by ORBi |
Strigun, A., Wahrheit, J., Beckers, S., Heinzle, E., & NOOR, F. (2011). Metabolic profiling using HPLC allows classification of drugs according to their mechanisms of action in HL-1 cardiomyocytes. Toxicology and Applied Pharmacology, 252 (2), 183-91. doi:10.1016/j.taap.2011.02.008 Peer Reviewed verified by ORBi |
Mueller, D., Tascher, G., Muller-Vieira, U., Knobeloch, D., Nuessler, A. K., Zeilinger, K., Heinzle, E., & NOOR, F. (2011). In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor. Journal of Tissue Engineering and Regenerative Medicine, 5 (8), 207-18. doi:10.1002/term.418 Peer Reviewed verified by ORBi |
Beckers, S., NOOR, F., Muller-Vieira, U., Mayer, M., Strigun, A., & Heinzle, E. (2010). High throughput, non-invasive and dynamic toxicity screening on adherent cells using respiratory measurements. Toxicology in vitro : an international journal published in association with BIBRA, 24 (2), 686-94. doi:10.1016/j.tiv.2009.04.018 Peer reviewed |
NOOR, F., Kinscherf, R., Bonaterra, G. A., Walczak, S., Wolfl, S., & Metzler-Nolte, N. (2009). Enhanced cellular uptake and cytotoxicity studies of organometallic bioconjugates of the NLS peptide in Hep G2 cells. Chembiochem: A European Journal of Chemical Biology, 10 (3), 493-502. doi:10.1002/cbic.200800469 Peer Reviewed verified by ORBi |
NOOR, F., Niklas, J., Muller-Vieira, U., & Heinzle, E. (2009). An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells. Toxicology and Applied Pharmacology, 237 (2), 221-31. doi:10.1016/j.taap.2009.03.011 Peer Reviewed verified by ORBi |
Niklas, J., NOOR, F., & Heinzle, E. (2009). Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2. Toxicology and Applied Pharmacology, 240 (3), 327-36. doi:10.1016/j.taap.2009.07.005 Peer Reviewed verified by ORBi |
NOOR, F., Wustholz, A., Kinscherf, R., & Metzler-Nolte, N. (2005). A cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery. Angewandte Chemie International Edition, 44 (16), 2429-32. doi:10.1002/anie.200462519 Peer reviewed |