Profil

RUMP Kirsten

University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Bioinformatics Core

ORCID
0000-0002-4394-7494
Main Referenced Co-authors
Hayden, M. R. (6)
Clee, S. M. (5)
Kastelein, J. J. (5)
Genest Jr., J. (4)
SCHNEIDER, Jochen  (4)
Main Referenced Keywords
Humans (10); Male (5); Adult (4); Aged (4); Female (4);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (6)
Luxembourg Centre for Systems Biomedicine (LCSB): Computational Biology (Del Sol Group) (2)
Luxembourg Centre for Systems Biomedicine (LCSB): Medical Translational Research (J. Schneider Group) (2)
Luxembourg Centre for Systems Biomedicine (LCSB) (1)
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (20)
Endocrinology, metabolism & nutrition (3)
Biochemistry, biophysics & molecular biology (3)
Cardiovascular & respiratory systems (1)
Human health sciences: Multidisciplinary, general & others (1)

Publications (total 26)

The most downloaded
194 downloads
Staaf, J., Labmayr, V., Paulmichl, K., Manell, H., Schneider, R., & Roomp, K. (2017). Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity. Pancreas. doi:10.1097/MPA.0000000000000771 https://hdl.handle.net/10993/29536

The most cited

1524 citations (Scopus®)

Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L. H., Rump, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O., Loubser, O., Ouelette, B. F., Fichter, K., Ashbourne-Excoffon, K. J., Sensen, C. W., Scherer, S., Mott, S., Denis, M., Martindale, D., ... Hayden, M. R. (August 1999). Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nature Genetics, 22 (4), 336-45. doi:10.1038/11905 https://hdl.handle.net/10993/3318

HANSEN, B., LACZNY, C. C., AHO, V., Frachet-Bour, A., Habier, J., OSTASZEWSKI, M., Michalsen, A., Hanslian, E., Koppold, D. A., Hartmann, A. M., Steckhan, N., Mollenhauer, B., Schade, S., RUMP, K., SCHNEIDER, J., & WILMES, P. (18 August 2023). Protocol for a multicentre cross-sectional, longitudinal ambulatory clinical trial in rheumatoid arthritis and Parkinson's disease patients analysing the relation between the gut microbiome, fasting and immune status in Germany (ExpoBiome). BMJ Open, 13 (8), 071380. doi:10.1136/bmjopen-2022-071380
Peer Reviewed verified by ORBi

Neininger, K., May, P., Altieri, B., Lippert, J. L., Roomp, K., Dalmazi, G. D., Canu, L., Ceccato, F., Riester, A., Herterich, S. L., Fassnacht, M., Schneider, J., & Ronchi, C. L. (03 May 2021). Evaluation of the Molecular Pathogenesis of Adrenocortical Tumors by Whole-Genome Sequencing. Journal of the Endocrine Society, 5 (Issue Supplement_1), 68. doi:10.1210/jendso/bvab048.137
Peer Reviewed verified by ORBi

Noor, F., Biemann, R., Roomp, K., Schneider, J., & Isermann, B. (20 October 2020). Gene expression profile of CD14+ blood monocytes following lifestyle-induced weight loss in individuals with metabolic syndrome. Scientific Reports, 10 (1), 17855. doi:10.1038/s41598-020-74973-2
Peer Reviewed verified by ORBi

Hipp Epouse D'amico, G., Vaillant, M., Diederich, N. J., Roomp, K., Satagopam, V., Banda, P., Sandt, E., Mommaerts, K., Schmitz, S., Longhino, L., Schweicher, A., Hanff, A.-M., Nicolai, B., Kolber, P. L., Reiter, D., Pavelka, L., Binck, S., Pauly, C., Geffers, L., ... Krüger, R. (29 October 2018). The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis. Frontiers in Aging Neuroscience, 10, 326. doi:10.3389/fnagi.2018.00326
Peer Reviewed verified by ORBi

Staaf, J., Labmayr, V., Paulmichl, K., Manell, H., Schneider, R., & Roomp, K. (2017). Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity. Pancreas. doi:10.1097/MPA.0000000000000771
Peer Reviewed verified by ORBi

Roomp, K., & Rand, J. (2015). Rebound hyperglycaemia in diabetic cats. Journal of Feline Medicine and Surgery, 1-10. doi:10.1177/1098612X15588967
Peer reviewed

Crespo, I., Rump, K., Jurkowski, W., Kitano, H., & del Sol Mesa, A. (2012). Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease. BMC Systems Biology, 6 (132). doi:10.1186/1752-0509-6-132
Peer Reviewed verified by ORBi

Roomp, K., & Rand, J. (2012). Evaluation of detemir in diabetic cats managed with a protocol for intensive blood glucose control. Journal of Feline Medicine and Surgery, 14 (8), 566-572. doi:10.1177/1098612X12446211
Peer reviewed

Roomp, K., & Domingues, F. S. (2011). Predicting interactions between T cell receptors and MHC-peptide complexes. Molecular Immunology, 48 (4), 553-562. doi:10.1016/j.molimm.2010.10.014
Peer Reviewed verified by ORBi

Jurkowski, W., Roomp, K., Crespo, I., Schneider, J., & del Sol Mesa, A. (2011). PPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome. Cell Death and Disease, 2 (8), 192. doi:10.1038/cddis.2011.74
Peer Reviewed verified by ORBi

Lange, C. M., Roomp, K., Dragan, A., Nattermann, J., Michalk, M., Spengler, U., Weich, V., Lengauer, T., Zeuzem, S., Berg, T., & Sarrazin, C. (2010). HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection. Journal of Hepatology, 53 (6), 1022-1028. doi:10.1016/j.jhep.2010.06.011
Peer reviewed

Roomp, K., Antes, I., & Lengauer, T. (2010). Predicting MHC class I epitopes in large datasets. BMC Bioinformatics, 11 (90), 1-2. doi:10.1186/1471-2105-11-90
Peer Reviewed verified by ORBi

Däumer, M., Awerkiew, S., Aragon, S. S., Kartashev, V., Poplavskaja, T., Klein, R., Sichtig, N., Thiele, B., Lengauer, T., Roomp, K., Pfister, H., & Kaiser, R. (2010). Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source. AIDS Research and Human Retroviruses, 26 (3), 275-278. doi:10.1089/aid.2009.0233
Peer Reviewed verified by ORBi

Roomp, K., & Rand, J. (2009). Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine. Journal of Feline Medicine and Surgery, 11 (8), 668-682. doi:10.1016/j.jfms.2009.04.010
Peer reviewed

Roomp, K., & Rand, J. S. (2008). The somogyi effect is rare in diabetic cats managed using glargine and a protocol aimed at tight glycemic control. Journal of Veterinary Internal Medicine, 22 (3), 790-791. doi:10.1111/j.1939-1676.2008.0103.x
Peer Reviewed verified by ORBi

Roomp, K., & Rand, J. S. (2008). Evaluation of intensive blood glucose control using glargine in diabetic cats. Journal of Veterinary Internal Medicine, 22 (3), 790.
Peer Reviewed verified by ORBi

Roomp, K., & Rand, J. S. (2008). Factors predictive of non-insulin dependence in diabetic cats initially treated with insulin. Journal of Veterinary Internal Medicine, 22 (3), 791. doi:10.1111/j.1939-1676.2008.0103.x
Peer Reviewed verified by ORBi

Ahlenstiel, G., Roomp, K., Daumer, M., Nattermann, J., Vogel, M., Rockstroh, J. K., Beerenwinkel, N., Kaiser, R., Nischalke, H. D., Sauerbruch, T., Lengauer, T., & Spengler, U. (2007). Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level. Clinical and Vaccine Immunology, 14 (10), 1266-1273. doi:10.1128/CVI.00169-07
Peer Reviewed verified by ORBi

Roomp, K., Beerenwinkel, N., Sing, T., Schülter, E., Büch, J., Sierra-Aragon, S., Däumer, M., Hoffmann, D., Kaiser, R., Lengauer, T., & Selbig, J. (2006). Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV. In U. Leser, F. Naumann, ... B. Eckman (Eds.), Data Integration in the Life Sciences (pp. 185-194). Springer-Verlag Berlin Heidelberg. doi:10.1007/11799511_16
Peer reviewed

Beerenwinkel, N., Sing, T., Lengauer, T., Rahnenführer, Roomp, K., Savenkov, I., Fischer, R., Hoffmann, D., Selbig, J., Korn, K., Walter, H., Berg, T., Braun, P., Fätkenheuer, Oette, M., Rockstroh, J., Kupfer, B., Kaiser, R., & Däumer. (2005). Computational methods for the design of effective therapies against drug resistant HIV strains. Bioinformatics, 21 (21), 3943-50. doi:10.1093/bioinformatics/bti654
Peer reviewed

Wellington, C. L., Yang, Y. Z., Zhou, S., Clee, S. M., Tan, B., Hirano, K., Zwarts, K., Kwok, A., Gelfer, A., Marcil, M., Newman, S., Roomp, K., Singaraja, R., Collins, J. A., Zhang, L. H., Groen, A. K., Hovingh, K., Brownlie, A., Tafuri, S., ... Hayden, M. R. (2002). Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol. Journal of Lipid Research, 43 (11), 1939-1949. doi:10.1194/jlr.M200277-JLR200
Peer reviewed

Nishida, Y., Hirano, K., Tsukamoto, K., Nagano, M., Ikegami, C., Roomp, K., Ishihara, M., Sakane, N., Zhang, Z., Tsujii Ki, K., Matsuyama, A., Ohama, T., Matsuura, F., Ishigami, M., Sakai, N., Hiraoka, H., Hattori, H., Wellington, C., Yoshida, Y., ... Matsuzawa, Y. (2002). Expression and functional analyses of novel mutations of ATP-binding cassette transporter-1 in Japanese patients with high-density lipoprotein deficiency. Biochemical and Biophysical Research Communications, 290 (2), 713-721. doi:10.1006/bbrc.2001.6219
Peer reviewed

Zwarts, K. Y., Clee, S. M., Zwinderman, A. H., Engert, J. C., Singaraja, R., Loubser, O., James, E., Roomp, K., Hudson, T. J., Jukema, J. W., Kastelein, J. J., & Hayden, M. R. (2002). ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels. Clinical Genetics, 61 (2), 115-125. doi:10.1034/j.1399-0004.2002.610206.x
Peer Reviewed verified by ORBi

Clee, S. M., Zwinderman, A. H., Engert, J. C., Zwarts, K. Y., Molhuizen, H. O., Roomp, K., Jukema, J. W., van Wijland, M., van Dam, M., Hudson, T. J., Brooks-Wilson, A., Genest Jr., J., Kastelein, J. J., & Hayden, M. R. (2001). Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation, 103 (9), 1198-1205. doi:10.1161/01.CIR.103.9.1198
Peer Reviewed verified by ORBi

Clee, S. M., Kastelein, J. J., van Dam, M., Marcil, M., Roomp, K., Zwarts, K. Y., Collins, J. A., Roelants, R., Tamasawa, N., Stulc, T., Suda, T., Ceska, R., Boucher, B., Rondeau, C., DeSouich, C., Brooks-Wilson, A., Molhuizen, H. O., Frohlich, J., Genest Jr., J., & Hayden, M. R. (2000). Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes. Journal of Clinical Investigation, 106 (10), 1263-1270. doi:10.1172/JCI10727
Peer reviewed

Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L. H., Rump, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O., Loubser, O., Ouelette, B. F., Fichter, K., Ashbourne-Excoffon, K. J., Sensen, C. W., Scherer, S., Mott, S., Denis, M., Martindale, D., ... Hayden, M. R. (August 1999). Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nature Genetics, 22 (4), 336-45. doi:10.1038/11905
Peer Reviewed verified by ORBi

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