Profil

GERARD Déborah

University of Luxembourg > Faculty of Science, Technology and Medicine (FSTM) > Department of Life Sciences and Medicine (DLSM)

ORCID
0000-0002-6083-6614
Main Referenced Co-authors
SINKKONEN, Lasse  (7)
SAUTER, Thomas  (6)
Dicato, Mario (5)
Diederich, Marc (5)
Christov, Christo (4)
Main Referenced Keywords
Acetylation (1); Active enhancers (1); Adipocytes (1); Adult (1); aging (1);
Main Referenced Unit & Research Centers
ULHPC - University of Luxembourg: High Performance Computing (2)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (14)
Neurology (1)

Publications (total 15)

The most downloaded
244 downloads
GERARD, D., Schmidt, F., GINOLHAC, A., SCHMITZ, M., HALDER, R., Ebert, P., Schulz, M., SAUTER, T., & SINKKONEN, L. (2018). Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency. Nucleic Acids Research. doi:10.1093/nar/gky1240 https://hdl.handle.net/10993/38244

The most cited

31 citations (OpenAlex)

Lernoux, M., Schnekenburger, M., Losson, H., Vermeulen, K., Hahn, H., GERARD, D., Lee, J.-Y., Mazumder, A., Ahamed, M., Christov, C., Kim, D.-W., Dicato, M., Bormans, G., Han, B. W., & Diederich, M. (2020). Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells. Clinical Epigenetics, 12 (1), 69. doi:10.1186/s13148-020-00839-z https://hdl.handle.net/10993/47925

Cerella, C., Gajulapalli, S. R., Lorant, A., GERARD, D., Muller, F., Lee, Y., Kim, K. R., Han, B. W., Christov, C., Récher, C., Sarry, J.-E., Dicato, M., & Diederich, M. (2023). ATP1A1/BCL2L1 predicts the response of myelomonocytic and monocytic acute myeloid leukemia to cardiac glycosides. Leukemia. doi:10.1038/s41375-023-02076-8
Peer Reviewed verified by ORBi

Soriano-Baguet, L., Grusdat, M., Kurniawan, H., Benzarti, M., Binsfeld, C., Ewen, A., LONGWORTH, J., Bonetti, L., Guerra, L., Franchina, D. G., Kobayashi, T., Horkova, V., Verschueren, C., Helgueta, S., GERARD, D., More, T. H., Henne, A., Dostert, C., Farinelle, S., ... Brenner, D. (2023). Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions. Cell Reports. doi:10.1016/j.celrep.2023.112153
Peer Reviewed verified by ORBi

Frangez, Z., GERARD, D., He, Z., GAVRIIL, M., Fernández-Marrero, Y., Seyed Jafari, M., Hunger, R., LUCARELLI, P., Yousefi, S., SAUTER, T., SINKKONEN, L., & Simon, H.-U. (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in Oncology. doi:10.3389/fonc.2021.721624
Peer Reviewed verified by ORBi

Radogna, F., GERARD, D., Dicato, M., & Diederich, M. (2021). Assessment of Mitochondrial Cell Metabolism by Respiratory Chain Electron Flow Assays. In V. Weissig & M. Edeas (Eds.), Methods in Molecular Biology. New York, United States: Springer. doi:10.1007/978-1-0716-1266-8_9
Peer reviewed

Walter, J., BOLOGNIN, S., Poovathingal, S., MAGNI, S., GERARD, D., ANTONY, P., NICKELS, S. L., Salamanca, L., Berger, E., SMITS, L., GRZYB, K., Perfeito, R., Hoel, F., Qing, X., OHNMACHT, J., Bertacchi, M., Jarazo, J., Ignac, T., Monzel, A., ... SCHWAMBORN, J. C. (2021). The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Reports. doi:10.1016/j.celrep.2021.109864
Peer Reviewed verified by ORBi

Losson, H., Gajulapalli, S. R., Lernoux, M., Lee, J.-Y., Mazumder, A., GERARD, D., Seidel, C., Hahn, H., Christov, C., Dicato, M., Kirsch, G., Han, B. W., Schnekenburger, M., & Diederich, M. (June 2020). The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia. Pharmacological Research, 160. doi:10.1016/j.phrs.2020.105058
Peer Reviewed verified by ORBi

Chateauvieux, S., GAIGNEAUX, A., GERARD, D., Orsini, M., Morceau, F., Orlikova-Boyer, B., Farge, T., Récher, C., Sarry, J.-E., Dicato, M., & Diederich, M. (June 2020). Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia [letter to the editor]. Haematologica, 105 (6), 280-E284. doi:10.3324/haematol.2019.217281
Peer reviewed

Song, S., Lee, J.-Y., Ermolenko, L., Mazumder, A., Ji, S., Ryu, H., KIM, H., Kim, D.-W., LEE, J., Dicato, M., Christov, C., Schnekenburger, M., Cerella, C., GERARD, D., Orlikova-Boyer, B., Al-Mourabit, A., & Diederich, M. (February 2020). Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia. Cell Death and Disease, 11 (2). doi:10.1038/s41419-020-2304-8
Peer reviewed

Grandjenettea, C., Schnekenburger, M., GAIGNEAUX, A., GERARD, D., Christov, C., Mazumder, A., Dicato, M., & Diederich, M. (2020). Human telomerase reverse transcriptase depletion potentiates the growth- T inhibitory activity of imatinib in chronic myeloid leukemia stem cells. Cancer Letters. doi:10.1016/j.canlet.2019.11.017
Peer Reviewed verified by ORBi

Lernoux, M., Schnekenburger, M., Losson, H., Vermeulen, K., Hahn, H., GERARD, D., Lee, J.-Y., Mazumder, A., Ahamed, M., Christov, C., Kim, D.-W., Dicato, M., Bormans, G., Han, B. W., & Diederich, M. (2020). Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells. Clinical Epigenetics, 12 (1), 69. doi:10.1186/s13148-020-00839-z
Peer Reviewed verified by ORBi

Klaus, C., Hansen, J. N., GINOLHAC, A., GERARD, D., Gnanapragassam, V. S., Horstkorte, R., Rossdam, C., Buettner, F. F. R., SAUTER, T., SINKKONEN, L., Neumann, H., & Linnartz-Gerlach, B. (2020). Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2020.01.008
Peer Reviewed verified by ORBi

BECKER, J. C., GERARD, D., GINOLHAC, A., SAUTER, T., & SINKKONEN, L. (2019). Identification of genes under dynamic post-transcriptional regulation from time-series epigenomic data. Epigenomics. doi:10.2217/epi-2018-0084
Peer Reviewed verified by ORBi

NICKELS, S., Walter, J., BOLOGNIN, S., GERARD, D., Jäger, C., Qing, X., Tisserand, J., JARAZO, J., Hemmer, K., Harms, A., HALDER, R., Lucarelli, P., Berger, E., ANTONY, P., GLAAB, E., Hankemeier, T., Klein, C., SAUTER, T., SINKKONEN, L., & SCHWAMBORN, J. C. (2019). Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism and Related Disorders. doi:10.1016/j.parkreldis.2019.09.018
Peer Reviewed verified by ORBi

GERARD, D., Schmidt, F., GINOLHAC, A., SCHMITZ, M., HALDER, R., Ebert, P., Schulz, M., SAUTER, T., & SINKKONEN, L. (2018). Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency. Nucleic Acids Research. doi:10.1093/nar/gky1240
Peer Reviewed verified by ORBi

GERARD, D. (2017). APPROACHES FOR IDENTIFICATION OF TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL REGULATORS OF MESENCHYMAL STEM CELL DIFFERENTIATION USING TIME-SERIES EPIGENOMIC DATA [Doctoral thesis, Unilu - University of Luxembourg]. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/33462

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