Article (Scientific journals)
Hyperbolic dispersion metasurfaces for molecular biosensing
Palermo, Giovanna; Sreekanth, Kandammathe Valiyaveedu; Maccaferri, Nicolò et al.
2021In Nanophotonics, 10 (1), p. 295–314
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Keywords :
Biosensing; Hyperbolic dispersion; Metamaterials; Metasurfaces
Abstract :
[en] Sensor technology has become increasingly crucial in medical research and clinical diagnostics to directly detect small numbers of low-molecular-weight biomolecules relevant for lethal diseases. In recent years, various technologies have been developed, a number of them becoming core label-free technologies for detection of cancer biomarkers and viruses. However, to radically improve early disease diagnostics, tracking of disease progression and evaluation of treatments, today’s biosensing techniques still require a radical innovation to deliver high sensitivity, specificity, diffusion-limited transport, and accuracy for both nucleic acids and proteins. In this review, we discuss both scientific and technological aspects of hyperbolic dispersion metasurfaces for molecular biosensing. Optical metasurfaces have offered the tantalizing opportunity to engineer wavefronts while its intrinsic nanoscale patterns promote tremendous molecular interactions and selective binding. Hyperbolic dispersion metasurfaces support high-k modes that proved to be extremely sensitive to minute concentrations of ultralow-molecular-weight proteins and nucleic acids.
Disciplines :
Physics
Author, co-author :
Palermo, Giovanna
Sreekanth, Kandammathe Valiyaveedu
Maccaferri, Nicolò ;  University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Physics and Materials Science Research Unit
Lio, Giuseppe Emanuele
Nicoletta, Giuseppe
De Angelis, Francesco
Hinczewski, Michael
Strangi, Giuseppe
External co-authors :
yes
Language :
English
Title :
Hyperbolic dispersion metasurfaces for molecular biosensing
Publication date :
2021
Journal title :
Nanophotonics
ISSN :
2192-8606
eISSN :
2192-8614
Publisher :
De Gruyter, Germany
Volume :
10
Issue :
1
Pages :
295–314
Peer reviewed :
Peer Reviewed verified by ORBi
Focus Area :
Physics and Materials Science
Available on ORBilu :
since 08 October 2020

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