References of "Scientific journals"
     in
Bookmark and Share    
Peer Reviewed
See detailHoeffding-ANOVA decompositions for symmetric statistics of exchangeable observations
Peccati, Giovanni UL

in Annals of Probability (2004), 32(3A), 1796--1829

Detailed reference viewed: 143 (0 UL)
Peer Reviewed
See detailSoziale Verantwortung – Zur Validierung des Konzepts anhand einer Chemnitzer Jugendstichprobe
Hadjar, Andreas UL; Baier, Dirk

in Soziale Probleme : Zeitschrift für Soziale Probleme und Soziale Kontrolle (2004), 15(2), 178-200

Detailed reference viewed: 61 (0 UL)
Full Text
Peer Reviewed
See detailActions, médiations et interactions : une approche multimodale du travail sur un chantier.
de Saint-Georges, Ingrid UL

in Cahiers de linguistique Française (2004), 26

Detailed reference viewed: 128 (1 UL)
Full Text
Peer Reviewed
See detailJob turnover, unemployment and labor market institutions
Joseph, Gilles; Pierrard, Olivier; Sneessens, Henri UL

in Labour Economics (2004), 11(4), 451-468

This paper studies the role of labor market institutions on unemployment and on the cyclical properties of job flows. We construct an intertemporal general equilib- rium model with search unemployment and ... [more ▼]

This paper studies the role of labor market institutions on unemployment and on the cyclical properties of job flows. We construct an intertemporal general equilib- rium model with search unemployment and endogenous job turnover, and examine the consequences of introducing an unemployment benefit, a firing cost and a downward wage rigidity. The model is able to reproduce the main cyclical properties of a typical European economy. It also suggests that downward wage rigidities, rather than unem- ployment benefit or firing cost, may well play a dominant role in explaining both the high unemployment rate and the cyclical properties of such an economy. [less ▲]

Detailed reference viewed: 296 (2 UL)
Full Text
Peer Reviewed
See detailA psychobiological perspective on genetic determinants of hypothalamus-pituitary-adrenal axis activity
Wüst, S.; Federenko, I. S.; Van Rossum, E. F. C. et al

in Annals of the New York Academy of Sciences (2004), 1032

Detailed reference viewed: 34 (0 UL)
Full Text
See detailCartable vert et poids plume. Quelles sont les représentations mentales et les habitudes des élèves en matière d’environnement ?
Vlassis, Joëlle UL; de Landsheere, Viviane; Crahay, Marcel

in Informations Pédagogiques (2004), 56

Detailed reference viewed: 63 (0 UL)
Peer Reviewed
See detailHeinz-Elmar Tenorth (Hrsg.): Klassiker der Pädagogik
Tröhler, Daniel UL

in Zeitschrift für Pädagogik (2004), 50

Detailed reference viewed: 228 (0 UL)
Full Text
Peer Reviewed
See detailEmpirical Likelihood Based Inference in Conditional Moment Restriction Models
Kitamura, Yuichi; Tripathi, Gautam UL; Ahn, Hyungtaik

in Econometrica (2004), 72

Detailed reference viewed: 126 (6 UL)
Full Text
Peer Reviewed
See detailDezentrale Konzentration – Leitbild für eine Region der kurzen Wege?
Hesse, Markus UL

in Die Erde (2004), 135(1), 127-128

Detailed reference viewed: 198 (0 UL)
Peer Reviewed
See detailEffizienz des Frühunterrichts: begleitende Forschung im Rahmen der Fremdsprachenreformen
Ziegler, Gudrun UL; Dauster, Judith

in Scandinavian Journal of Primary Health Care. Supplement (2004), (2), 24-28

Detailed reference viewed: 47 (0 UL)
Full Text
Peer Reviewed
See detailDepression, perceived control, and life satisfaction in university students from central-eastern and western Europe
Wardle, Jane; Steptoe, Andrew; Guliš, Gabriel et al

in International Journal of Behavioral Medicine (2004), 11

The poor health and psychological well-being of people in the former socialist states of Centeral-Eastern Europe are of serious concern and may be related to low perceived control. We compared depressive ... [more ▼]

The poor health and psychological well-being of people in the former socialist states of Centeral-Eastern Europe are of serious concern and may be related to low perceived control. We compared depressive symptoms, life satisfaction, and self-rated health in 3,571 male and female university students from 5 Western European countries and 4,793 students from 5 Central-Eastern European countries. Depression scores (short Beck Depression Inventory; Beck & Beck, 1972) were higher in Central-Eastern than Western European samples. The prevalence of low life satisfaction was also greater in Central-Eastern Europeans, but ratings of self-rated health did not differ. Ratings of perceived control were diminished, but sense of mastery and internal health locus of control were higher in Central-Eastern Europe. Depression and low life satisfaction were associated with low perceived control and mastery and with strong beliefs in the influence of chance over health. However, taking these factors into account did not explain the East-West difference in depressive symptoms and low life satisfaction. [less ▲]

Detailed reference viewed: 174 (0 UL)
Full Text
Peer Reviewed
See detailThe spatial Solow model
Camacho, Camen; Zou, Benteng UL

in Economics Bulletin (2004)

In this paper, we solve a Solow model in continuous time and space. We prove the existence of a solution to the problem and its convergence to a stationary solution. The simulations of various scenario in ... [more ▼]

In this paper, we solve a Solow model in continuous time and space. We prove the existence of a solution to the problem and its convergence to a stationary solution. The simulations of various scenario in the last section of the paper illustrates the convergence issue. [less ▲]

Detailed reference viewed: 72 (1 UL)
Full Text
Peer Reviewed
See detailChoice procedures in pairwise comparison multiple-attribute decision making methods
Bisdorff, Raymond UL; Roubens, M.

in Lecture Notes in Computer Science (2004), 3051

Detailed reference viewed: 90 (3 UL)
Full Text
Peer Reviewed
See detailA fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain
Tremuth, Laurent A; Kreis, Stephanie UL; Melchior, Chantal et al

in Journal of Biological Chemistry (2004), 279(21), 22258-22266

The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for integrin β subunits. Here, we report the ... [more ▼]

The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for integrin β subunits. Here, we report the precise delimitation and a first functional analysis of the talin rod domain integrin-binding site. Partially overlapping cDNAs covering the entire human talin gene were transiently expressed as DsRed fusion proteins in Chinese hamster ovary cells expressing α IIbβ 3, linked to green fluorescent protein (GFP). Two-color fluorescence analysis of the transfected cells, spread on fibrinogen, revealed distinct subcellular staining patterns including focal adhesion, actin filament, and granular labeling for different talin fragments. The rod domain fragment G (residues 1984-2344), devoid of any known actin- or vinculin-binding sites, colocalized with β 3-GFP in focal adhesions. Direct in vitro interaction of fragment G with native platelet integrin α IIbβ 3 or with the recombinant wild type, but not the Y747A mutant β 3 cytoplasmic tail, linked to glutathione S-transferase, was demonstrated by surface plasmon resonance analysis and pull-down assays, respectively. Here, we demonstrate for the first time the in vivo relevance of this interaction by fluorescence resonance energy transfer between β 3-GFP and DsRed-talin fragment G. Further in vitro pull-down studies allowed us to map out the integrin-binding site within fragment G to a stretch of 130 residues (fragment J, residues 1984-2113) that also localized to focal adhesions. Finally, we show by a cell biology approach that this integrin- binding site within the talin rod domain is important for β 3-cytoskeletal interactions but does not participate in α IIbβ 3 activation. [less ▲]

Detailed reference viewed: 154 (6 UL)
Full Text
Peer Reviewed
See detailAre there more than cross-selectional relationships of social support and social network with functional limitations and psychological distress in early rheumatoid arthritis ? The URIDISS longitudinal study
Demange, L.; Guillemin, F.; Baumann, Michèle UL

in Arthritis Care and Research (2004), 51(5), 782-791

Objective. To investigate whether greater social support and support network are cross-sectionally associated with less functional limitations and psychological distress in patients with early rheumatoid ... [more ▼]

Objective. To investigate whether greater social support and support network are cross-sectionally associated with less functional limitations and psychological distress in patients with early rheumatoid arthritis (RA); whether this association is constant over time; and whether increases in social support or support network are associated with less functional limitations and psychological distress. Methods. Subjects were from the European Research on Incapacitating Diseases and Social Support cohort and had early RA. Social support, support network, functional limitations (Health Assessment Questionnaire), and psychological distress (General Health Questionnaire) were assessed annually. Variance and covariance analyses with repeated measures were performed. Results. A total of 542 subjects were assessed for 3 years. On average, patients with a greater amount of specific social support or a stronger specific support network experienced less functional limitation and less psychological distress. Changes in a given subject’s functional limitations and psychological distress did not depend on his or her baseline social support or support network. Neither social support nor support network change over time. Conclusion. There may be a cross-sectional link between specific social support or support network and functional limitations and psychological distress, but no longitudinal association could be evidenced. [less ▲]

Detailed reference viewed: 105 (0 UL)
Peer Reviewed
See detailPhiliströse Genies, geniale Philister. Zum Niederlande-Bild in Ludwig Tiecks Novelle »Der funfzehnte November« (1827
Amann, Wilhelm UL

in Euphorion: Zeitschrift für Literaturgeschichte (2004), (4), 401-416

Detailed reference viewed: 76 (1 UL)
Peer Reviewed
See detailDesign of channel estimate dependent space-time block codes
Jöngren, George; Skoglund, Mikael; Ottersten, Björn UL

in IEEE Transactions on Communications (2004), 52(7), 11911203

Detailed reference viewed: 49 (0 UL)
See detailDer Staat als Arbeitgeber und die Entwicklung des öffentlichen Dienstes in Deutschland 1991-2001
Willems, Helmut UL; Czerwick, Edwin

in Verwaltungsrundschau (2004), 50. Jg(Heft 3), 82-89

Detailed reference viewed: 102 (0 UL)
See detailCrisi di liquidità dell’impresa e sospensione dell’esecuzione della sentenza ex art. 373 c.p.c.
Ratti, Luca UL

in Il Lavoro nella Giurisprudenza (2004)

Detailed reference viewed: 143 (0 UL)
Full Text
Peer Reviewed
See detailAgainst learning. Reclaiming a language for education in an age of learning.
Biesta, Gert UL

in Nordic Studies in Education (2004), 23

Detailed reference viewed: 2236 (1 UL)
Peer Reviewed
See detailNovel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
Hering, Robert; Strauss, Karsten M.; Tao, Xiao et al

in Human mutation (2004), 24(4), 321-9

Mutations in the parkin gene have been identified as a common cause of autosomal recessive inherited Parkinson disease (PD) associated with early disease manifestation. However, based on linkage data ... [more ▼]

Mutations in the parkin gene have been identified as a common cause of autosomal recessive inherited Parkinson disease (PD) associated with early disease manifestation. However, based on linkage data, mutations in other genes contribute to the genetic heterogeneity of early-onset PD (EOPD). Recently, two mutations in the DJ1 gene were described as a second cause of autosomal recessive EOPD (PARK7). Analyzing the PARK7/DJ1 gene in 104 EOPD patients, we identified a third mutation, c.192G>C (p.E64D), associated with EOPD in a patient of Turkish ancestry and characterized the functional significance of this amino acid substitution. In the patient, a substantial reduction of dopamine uptake transporter (DAT) binding was found in the striatum using [(18)F]FP-CIT and PET, indicating a serious loss of presynaptic dopaminergic afferents. His sister, homozygous for E64D, was clinically unaffected but showed reduced dopamine uptake when compared with a clinically unaffected brother, who is heterozygous for E64D. We demonstrate by crystallography that the E64D mutation does not alter the structure of the DJ1 protein, however we observe a tendency towards decreased levels of the mutant protein when overexpressed in HEK293 or COS7 cells. Using immunocytochemistry in contrast to the homogenous nuclear and cytoplasmic staining in HEK293 cells overexpressing wild-type DJ1, about 5% of the cells expressing E64D and up to 80% of the cells expressing the recently described L166P mutation displayed a predominant nuclear localization of the mutant DJ1 protein. [less ▲]

Detailed reference viewed: 164 (3 UL)
Peer Reviewed
See detailReduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice.
Luckow, Bruno; Joergensen, Joanne; Chilla, Silvia et al

in European Journal of Immunology (2004), 34(9), 2568-78

Experimental and human organ transplant studies suggest an important role for chemokine (C-C-motif) receptor-5 (CCR5) in the development of acute and chronic allograft rejection. Because early transplant ... [more ▼]

Experimental and human organ transplant studies suggest an important role for chemokine (C-C-motif) receptor-5 (CCR5) in the development of acute and chronic allograft rejection. Because early transplant damage can predispose allografts to chronic dysfunction, we sought to identify potential pathophysiologic mechanisms leading to allograft damage by using wild-type and Ccr5-deficient mice as recipients of fully MHC-mismatched heart and carotid-artery allografts. Gene expression in rejecting heart allografts was analyzed 2 and 6 days after transplantation using Affymetrix GeneChips. Microarray analysis led to identification of four metalloproteinase genes [matrix metalloproteinase (Mmp)3, Mmp12, Mmp13 and a disintegrin and metalloprotease domain (Adam)8] with significantly diminished intragraft mRNA expression in Ccr5-deficient mice at day 6. Accordingly, allografts from Ccr5-deficient mice showed less tissue remodeling and hence better preservation of the myocardial architecture compared with allografts from wild-type recipients. Moreover, survival of cardiac allografts was significantly increased in Ccr5-deficient mice. Carotid artery allografts from Ccr5-deficient recipients showed better tissue preservation, and significant reduction of neointima formation and CD3+ T cell infiltration. Ccr5 appears to play an important role in transplant-associated arteriosclerosis that may involve metalloproteinase-mediated vessel wall remodeling. We conclude that early tissue remodeling may be a critical feature in the predisposition of allografts to the development of chronic dysfunction. [less ▲]

Detailed reference viewed: 112 (0 UL)
Full Text
Peer Reviewed
See detailDesign of sheet pile installation by vibration
Van Baars, Stefan UL

in Geotechnical and Geological Engineering (2004), 22(3), 391-400

In the Netherlands 70% of the steel sheet piles are installed with vibrators. This is because vibrators have a high production rate and therefore a low installation cost. This method only works for soft ... [more ▼]

In the Netherlands 70% of the steel sheet piles are installed with vibrators. This is because vibrators have a high production rate and therefore a low installation cost. This method only works for soft peat and clay layers and saturated sand layers which are not densely compacted. During pile installation several problems might occur. In this paper the attention is paid to avoiding jamming of the pile before it has reached its planned depth. In most of these cases this is caused by a design error which has let to a vibrator which is too light. Over the years different design tools, such as computer models, design graphs and design equations, have been developed in order to predict the minimum required vibrator force. In this paper a new design equation is presented, which consists of three parts: the mass of the sheet pile, the friction along the shaft and the soil resistance at the tip of the pile based on the cone penetration resistance. This equation and several other design tools for sheet pile installation, have been compared with 18 field tests. It was found that the general design graphs of the Dutch Union of Foundation Contractors (NVAF), the design equation of the Dutch Civil Engineering Centre for Construction Research and Design Rules (CUR) and the German design equation of the EAU1996 gave very poor results. The computer model Vibdrive from Holeyman (1996), the design graphs for specific locations from the NVAF and the new presented design equation from the author gave reasonable predictions. Since the computer program is, because of its complexity, not regarded as a design tool for daily design work and the local design graphs only exist for a small number of locations in The Netherlands, the new design equation is according to the field tests the best method for the calculation of the vibrator needed for sheet pile installation. [less ▲]

Detailed reference viewed: 110 (0 UL)
Full Text
Peer Reviewed
See detailRational torsion of J_0(N) for hyperelliptic modular curves and families of Jacobians of genus 2 and genus 3 curves with a rational point of order 5, 7 or 10
Leprévost, Franck UL; Pohst, Michael; Schöpp, Andreas

in Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg (2004), 74

Detailed reference viewed: 131 (0 UL)
Full Text
Peer Reviewed
See detailNon observance des psychotropes: implication thérapeutique mutuelle du patient et du médecin généraliste
Baumann, Michèle UL; Baumann, C.; Alla, F.

in Presse Médicale (2004), 33(7), 445-448

Différencier, sur une période de 5 ans, les consommateurs de psychotropes non-observants (Nob), des observants (Ob) en fonction de leurs caractéristiques démographiques et de leurs opinions sur la ... [more ▼]

Différencier, sur une période de 5 ans, les consommateurs de psychotropes non-observants (Nob), des observants (Ob) en fonction de leurs caractéristiques démographiques et de leurs opinions sur la confiance accordée aux prescripteurs, les effets de la prise, le discours de l’entourage, les informations reçues. Méthode. Parmi 166 consommateurs âgés en moyenne de 55 ans, deux questions pour chaque psychotrope consommé pendant une durée de 5 ans ont permis de les classer en Ob ou Nob. Les données ont été recueillies par auto-questionnaire et entretien téléphonique. Résultats Trente-neuf pour cent des consommateurs ont été définis comme Nob. Les médicaments psychotropes sont prescrits en majorité par des médecins généralistes, dont la clientèle est moins souvent observante que celle des psychiatres. Les Nob sont plus enclins à ressentir les effets positifs après une prise et à déclarer pouvoir s’en passer. Quatre-vingt-dix pour cent des consommateurs déclarent porter un regard positif sur les psychotropes et 40% parlent de leur consommation à leur entourage ; les Nob sont plus nombreux à le faire. Seuls 12% des consommateurs ne cherchent pas d’informations sur les psychotropes car ils font confiance aux prescripteurs. Discussion Les consommateurs de psychotropes nécessitent une éducation thérapeutique mieux adaptée à leurs attentes. [less ▲]

Detailed reference viewed: 141 (5 UL)
Peer Reviewed
See detailAsymptotic Eigenvalue Distributions and Capacity for MIMO Channels under Correlated Fading
Martin, Cristoff; Ottersten, Björn UL

in IEEE Transactions on Wireless Communications (2004), 3(4), 13501359

Detailed reference viewed: 36 (0 UL)
Full Text
Peer Reviewed
See detailA prosopography of Breton rulership, A.D. 818-952
Pettiau, Hérold UL

in Journal of Celtic Studies (2004), 4

My aim in this article is to gather the contemporary sources dealing with Breton rulers and their relatives into a comprehensive and systematic prosopographical survey, dor it is striking to what extent ... [more ▼]

My aim in this article is to gather the contemporary sources dealing with Breton rulers and their relatives into a comprehensive and systematic prosopographical survey, dor it is striking to what extent received accounts rely on late texts. [less ▲]

Detailed reference viewed: 105 (3 UL)
Full Text
Peer Reviewed
See detailSchuldfähigkeit, Dissozialität und Psychopathy - eine Gutachtenanalyse
Schmidt, Alexander F. UL; Scholz, Oskar B.; Nedopil, Norbert

in Monatsschrift für Kriminologie und Strafrechtsreform (2004), 87

Theoretischer Hintergrund: Neuere Ansätze der Schuldfähigkeitsbegutachtung machen auf das Problem der differentialdiagnostischen Abgrenzung von Dissozialität und störungsbedingtem Verhalten aufmerksam ... [more ▼]

Theoretischer Hintergrund: Neuere Ansätze der Schuldfähigkeitsbegutachtung machen auf das Problem der differentialdiagnostischen Abgrenzung von Dissozialität und störungsbedingtem Verhalten aufmerksam. Aus differentialtypologischer Sicht kommt dem Psychopathy-Konstrukt sensu Hare hierbei eine besondere Bedeutung zu. Fragestellung: In welchem empirischem Zusammenhang mit der Schuldfähigkeit lässt sich das Psychopathy-Konstrukt als Extrembeispiel des dissozialen Typus finden? Methode: Aus einer Inhaltsanalyse von 33 Schuldfähigkeitsgutachten liegen die PCL-R Scores vor. Hieraus werden Gruppenunterschiede berechnet, Zusammenhangsmaße für Gesamtscore und Einzelfaktoren mit den jeweiligen Schuldfähigkeitsgruppen und das Klassifizierungsvermögen. Ergebnisse: Es findet sich kein statistisch bedeutsamer Unterschied zwischen Schuld- und vermindert Schuldfähigen. Für Faktor 2 der PCL-R findet sich ein mäßiger Zusammenhang mit verminderter Schuldfähigkeit und eine geringe diskriminatorische Bedeutung. Diskussion: Die Befunde werden vor den historisch-konventionalen Forderungen von Justiz und Psychiatrie einerseits und entwicklungspsychologischer Befunde zum Phänomen der Dissozialität andererseits diskutiert. [less ▲]

Detailed reference viewed: 515 (0 UL)
Peer Reviewed
See detailAction déclaratoire et droit judiciaire européen
Cuniberti, Gilles UL

in Journal du Droit International (2004)

Detailed reference viewed: 259 (1 UL)
Peer Reviewed
See detail«Le visuel au risque du médiatique dans les Bijoux de la Castafiore»
Roelens, Nathalie UL

in Contemporary French Civilization (2004)

Detailed reference viewed: 72 (1 UL)
See detailRahmen-Analysen der Wahrscheinlichkeit
Dembeck, Till UL

in IASL Online (2004)

Detailed reference viewed: 79 (0 UL)
Full Text
See detailNeutronen sehen Spinorientierung auf Nanoskala
Weissmüller, J.; Michels, Andreas UL

in Physik in unserer Zeit (2004), 35

Die attraktiven magnetischen Eigenschaften nanokristalliner Weichmagnete werden darauf zurückgeführt, dass bei geringer Kristallitgröße die Orientierung der Spins den Sprüngen in den magnetisch leichten ... [more ▼]

Die attraktiven magnetischen Eigenschaften nanokristalliner Weichmagnete werden darauf zurückgeführt, dass bei geringer Kristallitgröße die Orientierung der Spins den Sprüngen in den magnetisch leichten Richtungen von Kristallit zu Kristallit nicht mehr folgen kann. Physiker am Forschungszentrum Karlsruhe konnten jüngst diese Vorhersage mit Neutronenstreuung überprüfen. [less ▲]

Detailed reference viewed: 83 (1 UL)
Full Text
Peer Reviewed
See detailThe phonon dispersion of graphite revisited
Wirtz, Ludger UL; Rubio, A.

in Solid State Communications (2004), 131(3-4), 141-152

We review calculations and measurements of the phonon dispersion relation of graphite. First-principles calculations using density-functional theory are generally in good agreement with the experimental ... [more ▼]

We review calculations and measurements of the phonon dispersion relation of graphite. First-principles calculations using density-functional theory are generally in good agreement with the experimental data since the long-range character of the dynamical matrix is properly taken into account. Calculations with a plane-wave basis demonstrate that for the in-plane optical modes, the generalized-gradient approximation (GGA) yields frequencies lower by 2% than the local-density approximation (LDA) and is thus in better agreement with experiment. The long-range character of the dynamical matrix limits the validity of force-constant approaches that take only interaction with few neighboring atoms into account. However, by fitting the force-constants to the ab initio dispersion relation, we show that the popular 4th-nearest-neighbor force-constant approach yields an excellent fit for the low frequency modes and a moderately good fit (with a maximum deviation of 6%) for the high-frequency modes. If, in addition, the non-diagonal force-constant for the second-nearest neighbor interaction is taken into account, all the qualitative features of the high-frequency dispersion can be reproduced and the maximum deviation reduces to 4%. We present the new parameters as a reliable basis for empirical model calculations of phonons in graphitic nanostructures, in particular carbon nanotubes. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 92 (0 UL)
Peer Reviewed
See detailKunskapande som ett sätt att handla – John Deweys transaktionella teori om kunskapande.
Biesta, Gert UL

in Utbildning & demokrati (2004), 13(1), 41-64

Detailed reference viewed: 311 (0 UL)
Peer Reviewed
See detailUrbanization and growth
Bertinelli, Luisito UL; Black, Duncan

in Journal of Urban Economics (2004), 56(1), 80-96

In a simple urban economics framework, we aim at highlighting how the trade-off between optimal and equilibrium city size behaves when introducing dynamic human capital externalities beside the classical ... [more ▼]

In a simple urban economics framework, we aim at highlighting how the trade-off between optimal and equilibrium city size behaves when introducing dynamic human capital externalities beside the classical congestion externalities. Our purpose is to show that there are dynamic gains from oversized cities. To this end, we assume that productivity depends on human capital, which is solely accumulated in cities, such that urbanization is the engine of growth. In an empirical illustration, we highlight the link between urbanization and human capital accumulation, by focusing on cross-country panel data.<P>(This abstract was borrowed from another version of this item.) [less ▲]

Detailed reference viewed: 395 (1 UL)
Peer Reviewed
See detail«Report on the Louvain workshop "Les effets de matière comme synesthésies»
Roelens, Nathalie UL

in Zeitschrift für Semiotik (2004)

Detailed reference viewed: 46 (1 UL)
See detailPilotage et qualité du système éducatif.
Nicaise, Julien; Dierendonck, Christophe UL

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2004)

Detailed reference viewed: 93 (3 UL)
Peer Reviewed
See detailTime hierarchies in the Escherichia coli carbohydrate uptake and metabolism.
Kremling, A.; Fischer, S.; Sauter, Thomas UL et al

in Bio Systems (2004), 73(1), 57-71

The analysis of metabolic pathways with mathematical models contributes to the better understanding of the behavior of metabolic processes. This paper presents the analysis of a mathematical model for ... [more ▼]

The analysis of metabolic pathways with mathematical models contributes to the better understanding of the behavior of metabolic processes. This paper presents the analysis of a mathematical model for carbohydrate uptake and metabolism in Escherichia coli. It is shown that the dynamic processes cover a broad time span from some milliseconds to several hours. Based on this analysis the fast processes could be described with steady-state characteristic curves. A subsequent robustness analysis of the model parameters shows that the fast part of the system may act as a filter for the slow part of the system; the sensitivities of the fast system are conserved. From these findings it is concluded that the slow part of the system shows some robustness against changes in parameters of the fast subsystem, i.e. if a parameter shows no sensitivity for the fast part of the system, it will also show no sensitivity for the slow part of the system. [less ▲]

Detailed reference viewed: 102 (0 UL)
Peer Reviewed
See detail'Lebenslanges Lernen' als conditio humana: Ein Plädoyer für einen revidierten Lernbegriff
Tröhler, Daniel UL

in Vierteljahresschrift für wissenschaftliche Pädagogik (2004), 80

Detailed reference viewed: 57 (0 UL)
Peer Reviewed
See detailDécision de la Cour de cassation, 1ère Civ., 17 février 2004
Cuniberti, Gilles UL

in Clunet (2004)

Contrôle de la compétence du juge étranger

Detailed reference viewed: 46 (0 UL)
Peer Reviewed
See detail‘School’s just a catalyst.’ Learning, identity and knowledge and the Post-16 curriculum.
Lawy, R. S.; Bloomer, J. M.; Biesta, Gert UL

in Journal of Vocational Education and Training (2004), 56(2), 205-226

Detailed reference viewed: 53 (1 UL)
See detailAllgemeine Didaktik revisited
Tröhler, Daniel UL

in Beiträge zur Lehrerbildung (2004), 22

Detailed reference viewed: 55 (0 UL)
Full Text
Peer Reviewed
See detailUnequal-sphere packing model for the structural arrangement of the well-ordered adsorbate-substrate system
Tkatchenko, Alexandre UL; Batina, Nikola

in Physical Review. B, Condensed Matter and Materials Physics (2004), 70(19), 1-8

In order to understand the well-ordered adsorbate-substrate systems at atomic level, a method is developed based on the simulation of packing arrangements for layers of unequal spheres, in three ... [more ▼]

In order to understand the well-ordered adsorbate-substrate systems at atomic level, a method is developed based on the simulation of packing arrangements for layers of unequal spheres, in three-dimensional space. The model, based on geometrical principles, is developed for fee structure consisting of two hexagonal ordered layers. During simulation, adsorbate spheres were accommodated in different positions, forming a great variety of structures, in dependence of the intersphere distance of the upper layer spheres. Using the average height of the adsorbate layer on the flat substrate as a determinant parameter, several specific structures have been selected as the most probable: (√3 x √3)R30°, (√7 x √7)R19.1°, and (3 x 3). Indeed, they correspond to typical accommodations of the iodine adatoms on the Pt(111) surface, earlier found in experimental studies, which clearly supports the validity of our model. The model developed in our study could completely and satisfactorily describe the accommodation process of the iodine adlayer on the Pt(111) surface. This methodology could be of great help for interpretation of scanning tunneling microscopy images, better understanding of adlayer structures, and design of adsorbate-substrate systems with exciting properties. [less ▲]

Detailed reference viewed: 262 (9 UL)
Peer Reviewed
See detailReduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.
Conzelmann, H.; Saez-Rodriguez, J.; Sauter, Thomas UL et al

in Systems biology (2004), 1(1), 159-69

Biological systems and, in particular, cellular signal transduction pathways are characterised by their high complexity. Mathematical models describing these processes might be of great help to gain ... [more ▼]

Biological systems and, in particular, cellular signal transduction pathways are characterised by their high complexity. Mathematical models describing these processes might be of great help to gain qualitative and, most importantly, quantitative knowledge about such complex systems. However, a detailed mathematical description of these systems leads to nearly unmanageably large models, especially when combining models of different signalling pathways to study cross-talk phenomena. Therefore, simplification of models becomes very important. Different methods are available for model reduction of biological models. Importantly, most of the common model reduction methods cannot be applied to cellular signal transduction pathways. Using as an example the epidermal growth factor (EGF) signalling pathway, we discuss how quantitative methods like system analysis and simulation studies can help to suitably reduce models and additionally give new insights into the signal transmission and processing of the cell. [less ▲]

Detailed reference viewed: 256 (6 UL)
See detailIntergenerational attitudes towards Dutch language maintenance in New Zealand
De Bres, Julia UL

in Wellington Working Papers in Linguistics (2004), 16

This paper discusses the results of an exploratory study undertaken to investigate changes in individual and societal attitudes towards Dutch language maintenance across three periods of arrival in New ... [more ▼]

This paper discusses the results of an exploratory study undertaken to investigate changes in individual and societal attitudes towards Dutch language maintenance across three periods of arrival in New Zealand from the 1950s to the present. Eleven representatives of Dutch families of three different periods of arrival in New Zealand completed a written questionnaire enquiring about their level of Dutch proficiency, patterns of language use, and their attitudes and perceptions of societal attitudes towards Dutch language maintenance in New Zealand in the past and present. An analysis of the resulting data suggests that although intergenerational language shift has so far occurred at a similar rate across periods of arrival, individual and societal attitudes towards Dutch language maintenance are more positive today than in the 1950s, and these changes in attitude may impact on the degree of Dutch language maintenance in New Zealand. [less ▲]

Detailed reference viewed: 118 (1 UL)
Peer Reviewed
See detailA benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions.
Kremling, Andreas; Fischer, Sophia; Gadkar, Kapil et al

in Genome Research (2004), 14(9), 1773-85

A benchmark problem is described for the reconstruction and analysis of biochemical networks given sampled experimental data. The growth of the organisms is described in a bioreactor in which one ... [more ▼]

A benchmark problem is described for the reconstruction and analysis of biochemical networks given sampled experimental data. The growth of the organisms is described in a bioreactor in which one substrate is fed into the reactor with a given feed rate and feed concentration. Measurements for some intracellular components are provided representing a small biochemical network. Problems of reverse engineering, parameter estimation, and identifiability are addressed. The contribution mainly focuses on the problem of model discrimination. If two or more model variants describe the available experimental data, a new experiment must be designed to discriminate between the hypothetical models. For the problem presented, the feed rate and feed concentration of a bioreactor system are available as control inputs. To verify calculated input profiles an interactive Web site (http://www.sysbio.de/projects/benchmark/) is provided. Several solutions based on linear and nonlinear models are discussed. [less ▲]

Detailed reference viewed: 134 (0 UL)
Peer Reviewed
See detailPoursuite des procédures d'interdiction des déficits publics excessifs enregistrés par l'Allemagne et la France
Prüm, André UL

in Revue de Droit Bancaire et Financier (2004), (5),

Detailed reference viewed: 57 (0 UL)
Full Text
Peer Reviewed
See detailAggregate Matching Efficiency : A Stochastic Production Frontier Approach, France 1990-1994
Sneessens, Henri UL; Ibourk, Aomar; Maillard, Béatrice et al

in Empirica (2004), 31

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of ... [more ▼]

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of variables meant to capture workers and firms characteristics. The model is estimated on French data covering twenty-two regions from March 1990 till February 1995. Our estimates suggest that aggregate matching efficiency has decreased steadily in the early nineties. There are also wide cross-regional differences. On average, about 30% of the variations of efficiency observed across time and regions can be related to changes in the explanatory variables used in the model. The most important explanatory variables are the proportion of youngsters, females and immigrants in the stock of job seekers. Long-term unemployment has a significant negative effect, population density a significant positive one. The huge decline in the proportion of permanent job offers has apparently little effect on matching efficiency. [less ▲]

Detailed reference viewed: 97 (0 UL)
Full Text
Peer Reviewed
See detailInfluence of layer structure on performance of AlGaN/GaN High Electron Mobility Transistors before and after passivation
Bernát, J.; Javorka, P.; Fox, A. et al

in Journal of Electronic Materials (2004), 33((2004)), 436-439

Detailed reference viewed: 115 (1 UL)
Peer Reviewed
See detailThe acquisition of arithmetic knowledge - an FMRI study.
Delazer, Margarete; Domahs, Frank; Lochy, Aliette UL et al

in Cortex: A Journal Devoted to the Study of the Nervous System and Behavior (2004), 40(1), 166-7

Detailed reference viewed: 47 (1 UL)
Full Text
Peer Reviewed
See detailCanonical Brownian motion on the space of univalent functions and resolution of Beltrami equations by a continuity method along stochastic flows
Airault, Hélène; Malliavin, Paul; Thalmaier, Anton UL

in Journal de Mathématiques Pures et Appliquées (2004), 83(8), 955-1018

Detailed reference viewed: 182 (1 UL)
Full Text
Peer Reviewed
See detailVisualization of individual DNA loops and a map of loop domains in the human dystrophin gene
Iarovaia, Olga V.; Bystritskiy, Andrey; Ravcheev, Dmitry UL et al

in Nucleic Acids Research (2004), 32(7), 2079-2086

The organization of the human dystrophin gene into loop domains has been studied using two different experimental approaches: excision of DNA loops mediated by nuclear matrix-bound topoisomerase II and in ... [more ▼]

The organization of the human dystrophin gene into loop domains has been studied using two different experimental approaches: excision of DNA loops mediated by nuclear matrix-bound topoisomerase II and in situ hybridization of different probes with histone- depleted nuclei (nuclear halos). Our objective was to examine if the DNA loops mapped by this biochemical approach coincide with loops visualized by microscopy. The results obtained using both approaches were in good agreement. Eight loops separated by attachment regions of different length were mapped in the upstream part (up to exon 54) of the gene by topoisomerase II-mediated excision. One of these loops was then directly visualized by in situ hybridization of the corresponding bacmid clone with nuclear halos. This is the ®rst direct demonstration that a DNA domain mapped as a loop using a biochemical approach corresponds to a loop visible on cytological preparations. The validity of this result and of the whole map of loop domains was con®rmed by in situ hybridization using probes derived from other attachment regions or loops mapped by topoisomerase II-mediated cleavage; these probes hybridized on the core or halo region, respectively, of nuclear halos. Our results demonstrate that a single transcription unit may be organized into several loops and that DNA loop attachment regions may be fairly long. Three out of four replication origins mapped in this gene co-localize with loop attachment regions, and the major deletion hot spot is harbored in an attachment region. These results strongly suggest that partitioning of genomic DNA into speci®c loops attached to a skeletal structure is a characteristic feature of eukaryotic chromosome organization in interphase. [less ▲]

Detailed reference viewed: 84 (0 UL)
Full Text
Peer Reviewed
See detailImpact of layer structure on performance of unpassivated AlGaN/GaN/SiC HEMTs,
Bernát, J.; Wolter, M.; Fox, A. et al

in Electronics Letters (2004), 40(1), 78-80

The performance of unpassivated AlGaN=GaN=SiC HEMTs prepared on different MOVPE grown layer structures is reported. An overall improvement of device characteristics using doped structures in comparison to ... [more ▼]

The performance of unpassivated AlGaN=GaN=SiC HEMTs prepared on different MOVPE grown layer structures is reported. An overall improvement of device characteristics using doped structures in comparison to undoped counterpart is observed. This can be demonstrated by IDS of 0.86 and 1.33 A=mm, gm of 220 and 273 mS=mm, fT of 33 and 43 GHz and fmax of 54 and 61 GHz for 0.3 mm gate length devices on undoped and doped structures, respectively. The DC=pulsed I–V characteristics as well as power measurements show insignificant RF dispersion of HEMTs on doped structures. These results underline the advantage of doped layer structures for preparation of high-performance AlGaN=GaN HEMTs. [less ▲]

Detailed reference viewed: 67 (0 UL)
Peer Reviewed
See detailDas Ironbridge Gorge Museum. Ein Museum für die "Wiege der industriellen Revolution"
Helfer, Malte UL

in Geographie Heute (2004), (5), 19-23

Detailed reference viewed: 77 (1 UL)
Full Text
Peer Reviewed
See detailGradient of the Mechanical Modulus in Glass-Epoxy-Metal Joints as Measured by Brillouin Microscopy.
Krüger, Jan-Kristian UL; Possart, Wulff; Bactavatchalou, R. et al

in Journal of Adhesion (2004), 80(7), 585-599

The newly developed Brillouin microscopy is used for the first time to measure in situ the longitudinal elastic stiffness coefficient in the GHz-range inside of glass-epoxy-metal joints as a function of ... [more ▼]

The newly developed Brillouin microscopy is used for the first time to measure in situ the longitudinal elastic stiffness coefficient in the GHz-range inside of glass-epoxy-metal joints as a function of distance from the substrates. Interphases with a local variation of mechanical properties are quantitatively characterized. These interphases possess unexpected widths of tens to hundreds of microns. Inside the interphases, the spatial variation of the longitudinal stiffness coefficient depends on the type of substrate, on the curing conditions for the epoxy and probably on the distribution of internal stresses. The obtained spatial mechanical profiles provide valuable insight into the morphology-driven mechanics of the interphase, but additional information is needed for a full understanding of their physical and chemical origin. The presented results prove the sensitivity of the Brillouin microscopy; the elastic stiffness coefficients are detected with an accuracy in the subpercentage range. The spatial resolution is better than 10 µm. [less ▲]

Detailed reference viewed: 104 (0 UL)
Peer Reviewed
See detailArray Interpolation and Bias Reduction
Hyberg, Per; Jansson, Magnus; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (2004), 52(10), 27112720

Detailed reference viewed: 46 (0 UL)
Full Text
Peer Reviewed
See detail(-)-isopinocampheol substituted mesogens: An investigation of the effect of bulky terminal groups in chiral smectic liquid crystals
Yates, Chris; Lagerwall, Jan UL; Nobili, Maurizio et al

in Ferroelectrics (2004), 311

A ferroelectric liquid crystal with an end-substituted (-)-isopinocampheol (IPC) group has been studied in isolation and in mixtures with the antiferroelectric compound EHPOCBC. The samples were studied ... [more ▼]

A ferroelectric liquid crystal with an end-substituted (-)-isopinocampheol (IPC) group has been studied in isolation and in mixtures with the antiferroelectric compound EHPOCBC. The samples were studied with respect to electroclinic coefficients, tilt angles, X-ray layer spacing, dielectric permittivity, spontaneous polarisation and relative birefringence under an applied field. In the pure isopinocampheol substituted compound, the SmA-SmC phase transition appears strongly first order and is associated with a significant increase in effective birefringence. The smectic layer spacing decreases below the transition approximately with the optical tilt. On increased EHPOCBC concentration the change in birefringence across the transition diminishes, until the point at which the mixture adopts an anticlinic SmC(A) phase, and the expected decrease in birefringence is observed. There is very little change in birefringence with field for the IPC compound, whilst EHPOCBC shows a marked increase with increasing field, for a few degrees above the phase transition. The results are analyzed with respect to two models. In one it is proposed that the bulky IPC group disorders the SmA phase by introducing undulations in the smectic layer. These undulations may disappear in the SmC phase due to an antiparallel arrangement of neighbouring molecules. In the other model the bent shape of the mesogen as a whole plays a crucial role in changing the optical properties at the SmA-SmC transition, due to the biased rotation around the molecular axis of inertia. [less ▲]

Detailed reference viewed: 140 (1 UL)
See detailDetailed Mathematical Modeling of Metabolic and Regulatory Networks
Sauter, Thomas UL; Bullinger, E.

in BIOforum Europe (2004), 02

Detailed reference viewed: 151 (5 UL)
Full Text
Peer Reviewed
See detailLa France et l'Europe médiane: relations économiques et financières, 1919-1939
Clavert, Frédéric UL

in Valahian Journal of historical studies (2004), (2),

Detailed reference viewed: 69 (1 UL)
Full Text
Peer Reviewed
See detailConcordant outranking with multiple criteria of ordinal significance: A contribution to robust multicriteria aid for decision
Bisdorff, Raymond UL

in 4OR: a quarterly journal of operations research (2004), 2(4), 293-308

Detailed reference viewed: 59 (6 UL)
Full Text
Peer Reviewed
See detailThe sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity.
Schwamborn, Jens Christian UL; Puschel, Andreas W.

in Nature Neuroscience (2004), 7(9), 923-9

The establishment of a polarized morphology is an essential step in the differentiation of neurons with a single axon and multiple dendrites. In cultured rat hippocampal neurons, one of several initially ... [more ▼]

The establishment of a polarized morphology is an essential step in the differentiation of neurons with a single axon and multiple dendrites. In cultured rat hippocampal neurons, one of several initially indistinguishable neurites is selected to become the axon. Both phosphatidylinositol 3,4,5-trisphosphate and the evolutionarily conserved Par complex (comprising Par3, Par6 and an atypical PKC (aPKC) such as PKClambda or PKCzeta) are involved in axon specification. However, the initial signals that establish cellular asymmetry and the pathways that subsequently translate it into structural changes remain to be elucidated. Here we show that localization of the GTPase Rap1B to the tip of a single neurite is a decisive step in determining which neurite becomes the axon. Using GTPase mutants and RNA interference, we found that Rap1B is necessary and sufficient to initiate the development of axons upstream of Cdc42 and the Par complex. [less ▲]

Detailed reference viewed: 203 (2 UL)
Peer Reviewed
See detailEvaluation professionnelle compréhensive du programme obésité en Polynésie Française
Baumann, Michèle UL; Cao, M. M.

in Cahiers de Sociologie et de Démographie Médicales (2004), 44(2), 187-202

Detailed reference viewed: 80 (2 UL)
Full Text
Peer Reviewed
See detailQuality of life and attitudes towards psychotropics and dependency: consumers versus non-consumers aged 50 and over
Baumann, Michèle UL; Bonnetain, F.

in Journal of Clinical Pharmacy and Therapeutics (2004), 29

Aim: To assess the relationships between sociodemographic factors, quality of life and attitudes towards psychotropic drugs and dependency and to compare those relationships in continuous consumers (CC ... [more ▼]

Aim: To assess the relationships between sociodemographic factors, quality of life and attitudes towards psychotropic drugs and dependency and to compare those relationships in continuous consumers (CC), occasional consumers (OC) and non-consumers (NC) of those drugs. Methods: Quality of life (SF36) and attitudes (14 statements) were measured in 601 subjects (45–60 years old) from the SUVIMAX cohort (SUpple´mentation en VItamines et en sels Mine ´raux AntioXydants). Data were obtained on 334 NC, 142 CC, 125 OC from the inclusion questionnaire and the monthly consumption report notebooks kept by subjects between 1994 and 1998. Dichotomous and polychotomous logistic regressions were used for the analysis. Results: The lower the quality of life score the more frequent was consumption. NC tended to be men, with high quality of life scores. They entertained negative attitudes towards psychotropics and dependency. OC tended to be women reporting a chronic pathology, with fairly high social status. They had intermediate quality of life and denied dependency. CC tended to be men with no professional activity and low quality of life scores in particular for mental health and perceived health. They had positive attitudes towards psychotropics and accept dependency. Discussion: Assessment of patients’ quality of life and understanding of their attitudes towards psychotropics can provide essential information for those in charge of health promotionprogrammes and may help in identifying new intervention strategies. Preventive education and follow-up of therapy may be better suited to the needs of patients [less ▲]

Detailed reference viewed: 70 (3 UL)
Full Text
Peer Reviewed
See detailFormation and electronic properties of BC3 single-wall nanotubes upon boron substitution of carbon nanotubes
Fuentes, G. G.; Borowiak-Palen, E.; Knupfer, M. et al

in Physical Review. B (2004), 69(24),

We report a detailed experimental and theoretical study on the electronic and optical properties of highly boron-substituted (up to 15 at.%) single-wall carbon nanotubes. Core-level electron energy-loss ... [more ▼]

We report a detailed experimental and theoretical study on the electronic and optical properties of highly boron-substituted (up to 15 at.%) single-wall carbon nanotubes. Core-level electron energy-loss spectroscopy reveals that the boron incorporates into the lattice structure of the tubes, transferring similar to1/2 hole per boron atom into the carbon derived unoccupied density of states. The charge transfer and the calculated Fermi-energy shift in the doped nanotubes evidence that a simple rigid-band model can be ruled out and that additional effects such as charge localization and doping induced band-structure changes play an important role at this high doping levels. In optical absorption a new peak appears at 0.4 eV which is independent of the doping level. Compared to the results from a series of ab initio calculations our results support the selective doping of semiconducting nanotubes and the formation of BC3 nanotubes instead of a homogeneous random boron substitution. [less ▲]

Detailed reference viewed: 57 (2 UL)
Peer Reviewed
See detailKnowledge Dynamics in a Network Industry
Cowan, Robin; Jonard, Nicolas UL; Ozman, Muge

in Technological Forecasting and Social Change (2004), 71

Detailed reference viewed: 101 (0 UL)
Peer Reviewed
See detailNetwork Structure and the Diffusion of Knowledge
Cowan, Robin; Jonard, Nicolas UL

in Journal of Economic Dynamics and Control (2004), 28

Detailed reference viewed: 142 (2 UL)
Full Text
Peer Reviewed
See detailFree cortisol awakening responses are influenced by awakening time
Federenko, I.; Wüst, S.; Hellhammer, D. H. et al

in Psychoneuroendocrinology (2004), 29(2), 174-184

Detailed reference viewed: 28 (0 UL)
Full Text
Peer Reviewed
See detailVers un espace européen des paiements
Prüm, André UL

in Revue de Droit Bancaire et Financier (2004), (3), 1620-9435

Detailed reference viewed: 59 (0 UL)
Peer Reviewed
See detailInterferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals
Kortylewski, M.; Komyod, W.; Kauffmann, M. E. et al

in Journal of Investigative Dermatology (2004), 122(2), 414-22

Interferon-gamma, a known inhibitor of tumor cell growth, has been used in several protocols for the treatment of melanoma. We have studied the molecular events underlying interferon-gamma-induced G0/G1 ... [more ▼]

Interferon-gamma, a known inhibitor of tumor cell growth, has been used in several protocols for the treatment of melanoma. We have studied the molecular events underlying interferon-gamma-induced G0/G1 arrest in four metastatic melanoma cell lines with different responsiveness to interferon-gamma. The growth arrest did not result from enhanced expression of cyclin-dependent kinase inhibitors p21 and p27. Instead, it correlated with downregulation of cyclin E and cyclin A and inhibition of their associated kinase activities. We show that interferon-gamma-induced growth inhibition could be abrogated by overexpression of dominant negative STAT1 (signal transducer and activator of transcription 1) in the melanoma cell line A375, suggesting that STAT1 plays a crucial part for the anti-proliferative effect. Erythropoietin stimulation of a chimeric receptor led to a concentration-dependent STAT1 activation and concomitant growth arrest when it contained the STAT recruitment motif Y440 of the interferon-gamma receptor 1. In contrast, dose-response studies for interferon-gamma revealed a discrepancy between levels of STAT1 activation and the extent of growth inhibition; whereas STAT1 was activated by low doses of interferon-gamma (10 U per mL), growth inhibitory effects were only visible with 100-fold higher concentrations. Our results suggest the presence of additional signals emanating from the interferon-gamma receptor, which may counteract the anti-proliferative function of STAT1. [less ▲]

Detailed reference viewed: 77 (0 UL)
Peer Reviewed
See detailShared components of protein complexes--versatile building blocks or biochemical artefacts?
von Mering, Christian; Bork, Peer; Dandekar, Thomas et al

in BioEssays (2004), 26(12), 1333-43

Protein complexes perform many important functions in the cell. Large-scale studies of protein-protein interactions have not only revealed new complexes but have also placed many proteins into multiple ... [more ▼]

Protein complexes perform many important functions in the cell. Large-scale studies of protein-protein interactions have not only revealed new complexes but have also placed many proteins into multiple complexes. Whilst the advocates of hypothesis-free research touted the discovery of these shared components as new links between diverse cellular processes, critical commentators denounced many of the findings as artefacts, thus questioning the usefulness of large-scale approaches. Here, we survey proteins known to be shared between complexes, as established in the literature, and compare them to shared components found in high-throughput screens. We discuss the various challenges to the identification and functional interpretation of bona fide shared components, namely contaminants, variant and megacomplexes, and transient interactions, and suggest that many of the novel shared components found in high-throughput screens are neither the results of contamination nor central components, but appear to be primarily regulatory links in cellular processes. [less ▲]

Detailed reference viewed: 120 (1 UL)
Peer Reviewed
See detailLes Income Deposit Securities
Conac, Pierre-Henri UL

in Revue de Droit Bancaire et Financier (2004)

Detailed reference viewed: 76 (2 UL)
Peer Reviewed
See detailThe community of those who have nothing in common. Education and the language of responsibility.
Biesta, Gert UL

in Interchange (2004), 35(3), 307-324

Detailed reference viewed: 140 (0 UL)
Peer Reviewed
See detailHistoriography of Education: Philosophical Questions and Case Studies
Tröhler, Daniel UL; Oelkers, Jürgen

in Studies in Philosophy & Education (2004)

Detailed reference viewed: 130 (0 UL)
See detailHet is maar hoe je het bekijkt. Een experiment met filmseminaries voor orthopedagogiek en historische pedagogiek
Verstraete, Pieter; Van Hooste, Ann; Thyssen, Geert UL et al

in Leuvens Bulletin LAPP (2004), 53

Detailed reference viewed: 58 (0 UL)
Peer Reviewed
See detailMaking sense of the minus sign or becoming flexible in “negativity”
Vlassis, Joëlle UL

in Learning and Instruction (2004)

Detailed reference viewed: 184 (1 UL)
Full Text
Peer Reviewed
See detailA chameleon chiral polar liquid crystal: Rod-shaped when nematic, bent-shaped when smectic
Lagerwall, Jan UL; Giesselmann, Frank; Wand, Michael D. et al

in Chemistry of Materials (2004), 16(19), 3606-3615

The first antiferroelectric liquid crystal (AFLC) exhibiting a (chiral) nematic phase, a combination which has long been the goal of synthetic chemists working with polar liquid crystals but which at the ... [more ▼]

The first antiferroelectric liquid crystal (AFLC) exhibiting a (chiral) nematic phase, a combination which has long been the goal of synthetic chemists working with polar liquid crystals but which at the same time represents a fundamental contradiction in terms of translational order, was recently reported by Nishiyama and co-workers. We have investi- gated this chiral twin dimer by optic, electrooptic, and dielectric methods and conclude that it is not an ordinary AFLC material, but one where the peculiar properties of bent-core smectics are combined with those of ordinary rod-shaped liquid crystals. The compound exhibits a new type of nematic-smectic phase transition, connected with a change of molecule conformation from rod- to bent-shaped. This also has an important impact on the chiral interactions in the system. Toward the high-temperature end of the smectic phase, the energy balance between bent conformation smectic and straight conformation nematic can be shifted by an electric field such that the transition to the nematic phase with stretched-out molecules can be field-induced. [less ▲]

Detailed reference viewed: 131 (1 UL)
Full Text
See detailLa Vie de saint Fructueux de Braga. Quelques aspects de la realtion entre l'ascète et la société en Espagne wisigothique
Pettiau, Hérold UL

in Britannia Monastica (2004), 8

Cette contribution est consacrée à l'étude de certains aspects de la représentation hagiographique de saint Fructueux, évêque de Dumio à partir de ca. 653 et de Braga, métropole ecclésiastique de la ... [more ▼]

Cette contribution est consacrée à l'étude de certains aspects de la représentation hagiographique de saint Fructueux, évêque de Dumio à partir de ca. 653 et de Braga, métropole ecclésiastique de la province de Gallaecia, de 656 à 675 au plus tard. Cette vita adopte une perspective monastique très marquée, accordant peu d'attention aux activités du saint en tant qu'évêque. Au contraire, l'hagiographe s'attache à évoquer les fondations monastiques ainsi que les tendances érémitiques du saint. On analysera aussi dans cette contribution les tensions causées par les activités du saint, et exprimées dans un contexte juridique séculier. [less ▲]

Detailed reference viewed: 123 (1 UL)
See detailReview of D. Herman: Narrative Theory and the Cognitive Sciences
Weber, Jean-Jacques UL

in BELL. Belgian Essays on Language and Literature (2004), 2

Detailed reference viewed: 97 (0 UL)
Full Text
Peer Reviewed
See detailPerformance of unpassivated AlGaN/GaN/SiC HEMTs after short-term electrical bias stress
Bernát, J.; Wolter, M.; Javorka, P. et al

in Solid-State Electronics (2004), 48((2004)), 1825-1828

Performance of unpassivated MOVPE grown AlGaN/GaN/SiC HEMTs under short-term electrical bias stress isreported. Insignificant degradation in DC and RF behaviour of prepared devices after 16 h stress at VD ... [more ▼]

Performance of unpassivated MOVPE grown AlGaN/GaN/SiC HEMTs under short-term electrical bias stress isreported. Insignificant degradation in DC and RF behaviour of prepared devices after 16 h stress at VD ¼ 21 V and VG ¼ 2:5 V is observed. This can be demonstrated by a maximum drain current of 1.03 and 1.01 A/mm and a peak extrinsic transconductance of 233 and 225 mS/mm before and after bias stress, respectively. Consecutive drain voltage sweeps indicates on low current collapse in samples investigated. The RF characteristics show a decrease of the fmax-tof T ratio from 2.23 to 2.15 and the saturated output power density measured at 2 GHz from 3.60 to 3.53 W/mm after the devices were stressed. This result indicates that reliable AlGaN/GaN/SiC HEMTs without passivation can be prepared. However, additional studies are needed to understand if the material structure and/or the device processing is responsible for low current collapse and RF dispersion in these devices. [less ▲]

Detailed reference viewed: 89 (0 UL)
Full Text
Peer Reviewed
See detailBook review of : H. SCHILLING. Die neue Zeit. Vom Christenheitseuropa zum Europa der Staaten. 1250 bis 1750, 1999
Weis, Monique UL

in Revue Belge de Philologie et d'Histoire (2004), 82

Detailed reference viewed: 9 (0 UL)
Peer Reviewed
See detailAntiapoptotic effects of budipine.
Muller, T.; Przuntek, H.; Krüger, Rejko UL et al

in Journal of Neural Transmission (2004), 111(10-11), 1365-73

Apoptosis is one essential step for neuronal death in the nigrostriatal region in patients with Parkinson's disease. Cytotoxic tumor necrosis factor-alpha (TNF-alpha) and the proinflammatory cytokine ... [more ▼]

Apoptosis is one essential step for neuronal death in the nigrostriatal region in patients with Parkinson's disease. Cytotoxic tumor necrosis factor-alpha (TNF-alpha) and the proinflammatory cytokine interleukin-6 (Il-6) provide a proapoptotic environment. We investigated the influence of the antiparkinsonian compound budipine on the release of TNF-alpha and Il-6 in peripheral blood mononuclear cells (PBMC) and on the degree of cisplatin induced apoptotic cell death in SH-SY 5Y human neuroblastoma cells. 10(-7), 10(-8), 10(-9) mol/l of budipine significantly reduced release of TNF-alpha and Il-6 in PBMC and decreased apoptotic cell death after 50 hours and 74 hours in the SH-SY 5Y cells. Our results suggest, that budipine administration provides an antiapoptotic environment and slows neuronal apoptotic and inflammatory mediated loss of neurons. [less ▲]

Detailed reference viewed: 118 (1 UL)
Peer Reviewed
See detailWie wird Leistungsorientierung von den Eltern auf die Kinder übertragen? Ergebnisse einer Längsschnittstudie
Baier, Dirk; Hadjar, Andreas UL

in Zeitschrift für Familienforschung (2004), 16(2), 156-177

Detailed reference viewed: 522 (0 UL)
Peer Reviewed
See detailModeling and experimental validation of the signal transduction via the Escherichia coli sucrose phospho transferase system.
Sauter, Thomas UL; Gilles, E. D.

in Journal of Biotechnology (2004), 110(2), 181-99

Bacterial signal processing was investigated concerning the sucrose phosphotransferase system (sucrose PTS) in the bacterium Escherichia coli as an example. The about 20 different phosphotransferase ... [more ▼]

Bacterial signal processing was investigated concerning the sucrose phosphotransferase system (sucrose PTS) in the bacterium Escherichia coli as an example. The about 20 different phosphotransferase systems (PTSs) of the cell fulfill besides the transport of various carbohydrates, also the function of one signal processing system. Extra- and intracellular signals are converted within the PTS protein chain to important regulatory signals affecting, e.g. carbon metabolism and chemotaxis. A detailed dynamical model of the sucrose PTS was developed describing transport and signal processing function. It was formulated using a detailed description of complex formation and phosphate transfer between the chain proteins. Model parameters were taken from literature or were identified with own experiments. Simulation studies together with experimental hints showed that the dynamic behavior of phosphate transfer in the PTS runs within 1 s. Therefore a description of steady state characteristics is sufficient for describing the signaling properties of the sucrose PTS. A steady state characteristic field describes the degree of phosphorylation of the PTS protein EIIACrr as a function of the input variables extracellular sucrose concentration and intracellular phosphoenolpyruvate (PEP):pyruvate ratio. The model has been validated with different experiments performed in a CSTR using a sucrose positive E. coli W3110 derivative. A method for determining intracellular metabolite concentrations has been developed. A sample preparation technique using a boiling ethanol buffer solution was successfully applied. The PTS output signal degree of phosphorylation of EIIACrr was also measured. Steady state conditions with varying dilution rate and dissolved oxygen concentration and dynamical variations applying different stimuli to the culture were considered. Pulse, and stop feeding experiments with limiting sucrose concentrations were performed. Simulation and experimental results matched well. The same holds for the expanded sucrose PTS and glycolysis model. [less ▲]

Detailed reference viewed: 120 (1 UL)
Peer Reviewed
See detailWeak convergence to Ocone martingales: a remark
Peccati, Giovanni UL

in Electronic Communications in Probability (2004), 9

Detailed reference viewed: 221 (0 UL)
Full Text
Peer Reviewed
See detailSelf-poisoning of crystal nuclei in hard-rod liquids
Schilling, Tanja UL; Frenkel, Daan

in Journal of Physics : Condensed Matter (2004), 16(19), 2029-2036

We report a Monte Carlo study of the pathway for crystal nucleation in a fluid of hard, colloidal rods. In the earliest stages of nucleation, a lamellar crystallite forms. Subsequent thickening of this ... [more ▼]

We report a Monte Carlo study of the pathway for crystal nucleation in a fluid of hard, colloidal rods. In the earliest stages of nucleation, a lamellar crystallite forms. Subsequent thickening of this lamella is hampered by the fact that the top and bottom surfaces of this crystallite are preferentially covered by rods that align parallel to the surface. As a consequence, subsequent growth of individual crystals is stunted. Experimental evidence for such stunted crystal growth has recently been reported by Maeda and Maeda in experiments on suspensions of colloidal rods [Phys. Rev. Lett. 90, 018303 (2003)]. The simulations suggest that, in experiments, the growth of multilayer colloidal crystals can be selectively enhanced by the application of an external aligning field. [less ▲]

Detailed reference viewed: 93 (2 UL)
Peer Reviewed
See detailCommentaire de Cass. soc., 28 janv. 2004, le cumul d'un contrat de travail et de la qualité de dirigeant de SCOP
Hiez, David UL

in La Semaine Juridique - Entreprise et Affaires (2004), 2(833), 920-923

Detailed reference viewed: 63 (0 UL)
Peer Reviewed
See detailLanguage planning in the Pacific: Endangered English-based creoloids on Norfolk and Palmerston Islands
Ehrhart, Sabine UL; Mair, Christian; Mühlhäusler, Peter

in Alauda (2004), 614

Detailed reference viewed: 64 (0 UL)
Full Text
See detailMitten am Rand. Vorstadt, Suburbia, Zwischenstadt.
Hesse, Markus UL

in Kommune (2004), 22(5), 70-74

Detailed reference viewed: 194 (1 UL)
Full Text
Peer Reviewed
See detailPhonon and plasmon excitation in inelastic electron tunneling spectroscopy of graphite
Vitali, L.; Schneider, M. A.; Kern, K. et al

in Physical Review. B (2004), 69(12),

The inelastic electron tunneling spectrum (IETS) of highly oriented pyrolitic graphite has been measured with scanning tunneling spectroscopy (STS) at 6 K. The observed spectral features are in very good ... [more ▼]

The inelastic electron tunneling spectrum (IETS) of highly oriented pyrolitic graphite has been measured with scanning tunneling spectroscopy (STS) at 6 K. The observed spectral features are in very good agreement with the vibrational density of states of graphite calculated from first principles. We discuss the enhancement of certain phonon modes by phonon-assisted tunneling in STS based on the restrictions imposed by the electronic structure of graphite. We also demonstrate the local excitation of surface plasmons in IETS, which are detected at an energy of 40 meV. [less ▲]

Detailed reference viewed: 136 (3 UL)
Peer Reviewed
See detailNew developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications.
Storch, Alexander; Hofer, Anne; Krüger, Rejko UL et al

in Journal of neurology (2004), 251 Suppl 6

In this review we summarize new developments in early diagnosis, establishing surrogate markers, genetics, neuroprotection and cell replacement in Parkinson's disease. Furthermore, we discuss the major ... [more ▼]

In this review we summarize new developments in early diagnosis, establishing surrogate markers, genetics, neuroprotection and cell replacement in Parkinson's disease. Furthermore, we discuss the major problems in the translation of results from preclinical research into successful clinical trials. [less ▲]

Detailed reference viewed: 125 (0 UL)
Full Text
Peer Reviewed
See detailEndogenous Qualifications and Firms' Agglomeration
Toulemonde, Eric; Picard, Pierre M UL

in Journal of Urban Economics (2004), 55(3), 458-477

This paper analyzes firms' location when workers endogenously choose to qualify for professional skills but when they remain uncertain about the potential match between their personal abilities and/or ... [more ▼]

This paper analyzes firms' location when workers endogenously choose to qualify for professional skills but when they remain uncertain about the potential match between their personal abilities and/or affinities and the firms' specific production tasks. By qualifying in a region where firms agglomerate, workers benefit from higher prospects of good match. At the equilibrium, we show that firms may locate in a single cluster, symmetric clusters or even asymmetric clusters. Comparative statics with respect to product market demand and labor supply parameters are provided. [less ▲]

Detailed reference viewed: 90 (1 UL)