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See detailThe mod 2 cohomology rings of congruence subgroups in the Bianchi groups
Berkove, Ethan; Lakeland, Grant; Rahm, Alexander UL

E-print/Working paper (in press)

We provide new tools for the calculation of the torsion in the cohomology of congruence subgroups in the Bianchi groups : An algorithm for finding particularly useful fundamental domains, and an analysis ... [more ▼]

We provide new tools for the calculation of the torsion in the cohomology of congruence subgroups in the Bianchi groups : An algorithm for finding particularly useful fundamental domains, and an analysis of the equivariant spectral sequence combined with torsion subcomplex reduction. [less ▲]

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See detailBorder or bordering practice? Changing perspectives on borders and challenges of praxeological approaches
Connor, Ulla UL

E-print/Working paper (2021)

In Border Studies, the ongoing discussions on methodological and theoretical questions have led to the development of transformed approaches and vocabulary for border research. This contribution ... [more ▼]

In Border Studies, the ongoing discussions on methodological and theoretical questions have led to the development of transformed approaches and vocabulary for border research. This contribution highlights the shift from ‘border’ to ‘bordering practice’ and questions its sources in the scientific context, such as the cultural turn and the related practice turn. Despite the popular use of the term ‘practice’ in Border Studies, sociological practice theories are not at the center of the development of dynamic concepts for studying borders. The article emphasizes the compatibility of sociological practice theories with the practice and process orientation in Border Studies. It gives a short overview of praxeological thinking in sociology and identifies methodological challenges for Border Studies targeting the development of praxeological re-search perspectives for borders. [less ▲]

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See detailEmpowering Large Chemical Knowledge Bases for Exposomics: PubChemLite Meets MetFrag
Schymanski, Emma UL; Kondic, Todor UL; Neumann, Steffen et al

E-print/Working paper (2020)

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See detailSARS-CoV-2 Transmission in Educational Settings During an Early Summer Epidemic Wave in Luxembourg
Mossong, Joël; Mombaerts, Laurent UL; Veiber, Lisa UL et al

E-print/Working paper (2020)

Background: The role of schools and children in the transmission of SARS-CoV-2 remains to be determined. Following a first wave in spring and gradual easing of lockdown, Luxembourg experienced an early ... [more ▼]

Background: The role of schools and children in the transmission of SARS-CoV-2 remains to be determined. Following a first wave in spring and gradual easing of lockdown, Luxembourg experienced an early second epidemic wave before the start of summer school holidays on 15th July. This provided the opportunity to study the role of school-age children and school settings in SARS-CoV-2 transmission. More specifically, we compared the incidence in school-age children, teachers and the general working population, and estimated the number of secondary transmissions occurring at schools using contact tracing data. Findings: While SARS-CoV-2 incidence was much higher in adults aged 20 and above than in children aged 0 to 19 during the first wave in spring, no significant difference was found during the second wave in early summer. The incidence during the second wave was similar for pupils, teachers and the general working population. Based on a total of 424 reported confirmed COVID-19 cases in school-age children and teachers, we estimate that 179 index cases caused 49 secondary transmissions in schools. While some small clusters of mainly student-to-student transmission within the same class were identified, we did not observe any large outbreaks with multiple generations of infection. Interpretation: Transmission of SARS-CoV-2 within Luxembourg schools was limited during the early summer epidemic wave in 2020. Precautionary measures including physical distancing as well as easy access to testing, systematic contact tracing appears to have been successful in mitigating transmission within educational settings. Funding Statement: LV is supported by the Luxembourg National Research Fund grant COVID-19/2020- 1/14701707/REBORN, LM is supported by Luxembourg National Research Fund grant COVID19/14863306/PREVID, PW is supported by the European Research Council (ERC-CoG 863664). Declaration of Interests: No competing interests. Ethics Approval Statement: The Health Directorate has the legal permission to process patient confidential information for national surveillance of communicable diseases in general and contact tracing for the COVID-19 pandemic and individual patient consent is not required. [less ▲]

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See detailDimension-free Harnack inequalities for conjugate heat equations and their applications to geometric flows
Cheng, Li-Juan; Thalmaier, Anton UL

E-print/Working paper (2020)

Let M be a differentiable manifold endowed with a family of complete Riemannian metrics g(t) evolving under a geometric flow over the time interval [0,T[. In this article, we give a probabilistic ... [more ▼]

Let M be a differentiable manifold endowed with a family of complete Riemannian metrics g(t) evolving under a geometric flow over the time interval [0,T[. In this article, we give a probabilistic representation for the derivative of the corresponding conjugate semigroup on M which is generated by a Schrödinger type operator. With the help of this derivative formula, we derive fundamental Harnack type inequalities in the setting of evolving Riemannian manifolds. In particular, we establish a dimension-free Harnack inequality and show how it can be used to achieve heat kernel upper bounds in the setting of moving metrics. Moreover, by means of the supercontractivity of the conjugate semigroup, we obtain a family of canonical log-Sobolev inequalities. We discuss and apply these results both in the case of the so-called modified Ricci flow and in the case of general geometric flows. [less ▲]

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See detailA generalization of Krull-Webster's theory to higher order convex functions: multiple gamma-type functions
Marichal, Jean-Luc UL; Zénaïdi, Naïm

E-print/Working paper (2020)

We provide uniqueness and existence results for the eventually $p$-convex and eventually $p$-concave solutions to the difference equation $\Delta f=g$ on the open half-line $(0,\infty)$, where $p$ is a ... [more ▼]

We provide uniqueness and existence results for the eventually $p$-convex and eventually $p$-concave solutions to the difference equation $\Delta f=g$ on the open half-line $(0,\infty)$, where $p$ is a given nonnegative integer and $g$ is a given function satisfying the asymptotic property that the sequence $n\mapsto\Delta^p g(n)$ converges to zero. These solutions, that we call $\log\Gamma_p$-type functions, include various special functions such as the polygamma functions, the logarithm of the Barnes $G$-function, and the Hurwitz zeta function. Our results generalize to any nonnegative integer $p$ the special case when $p=1$ obtained by Krull and Webster, who both generalized Bohr-Mollerup-Artin's characterization of the gamma function. We also follow and generalize Webster's approach and provide for $\log\Gamma_p$-type functions analogues of Euler's infinite product, Weierstrass' infinite product, Gauss' limit, Gauss' multiplication formula, Legendre's duplication formula, Euler's constant, Stirling's constant, Stirling's formula, Wallis's product formula, and Raabe's formula for the gamma function. We also introduce and discuss analogues of Binet's function, Burnside's formula, Fontana-Mascheroni's series, Euler's reflection formula, and Gauss' digamma theorem. Lastly, we apply our results to several special functions, including the Hurwitz zeta function and the generalized Stieltjes constants, and show through these examples how powerful is our theory to produce formulas and identities almost systematically. [less ▲]

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See detailOn the Composition and Limitations of Publicly Available COVID-19 X-Ray Imaging Datasets
Garcia Santa Cruz, Beatriz UL; Sölter, Jan UL; Bossa, Matias Nicolas UL et al

E-print/Working paper (2020)

 Machine learning based methods for diagnosis and progression prediction of COVID-19 from imaging data have gained significant attention in the last months, in particular by the use of deep learning ... [more ▼]

 Machine learning based methods for diagnosis and progression prediction of COVID-19 from imaging data have gained significant attention in the last months, in particular by the use of deep learning models. In this context hundreds of models where proposed with the majority of them trained on public datasets. Data scarcity, mismatch between training and target population, group imbalance, and lack of documentation are important sources of bias, hindering the applicability of these models to real-world clinical practice. Considering that datasets are an essential part of model building and evaluation, a deeper understanding of the current landscape is needed. This paper presents an overview of the currently public available COVID-19 chest X-ray datasets. Each dataset is briefly described and potential strength, limitations and interactions between datasets are identified. In particular, some key properties of current datasets that could be potential sources of bias, impairing models trained on them are pointed out. These descriptions are useful for model building on those datasets, to choose the best dataset according the model goal, to take into account the specific limitations to avoid reporting overconfident benchmark results, and to discuss their impact on the generalisation capabilities in a specific clinical setting. [less ▲]

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See detailTerritorial patterns and relations in Austria
Szendrei, Greta UL; Evrard, Estelle UL; Nienaber, Birte UL et al

E-print/Working paper (2020)

Detailed reference viewed: 31 (3 UL)
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See detailThe Flow of Information Among Authorities Involved in the Banking Union’s Resolution Procedure: The Case of the SRB and the ECB
Lupinu, Pier Mario UL

E-print/Working paper (2020)

The flow of information is vital for the smooth functioning and certainty of the successful outcome of a resolution procedure during resolution planning and execution. As a result, the exchange of ... [more ▼]

The flow of information is vital for the smooth functioning and certainty of the successful outcome of a resolution procedure during resolution planning and execution. As a result, the exchange of relevant information has become highly influential in current debates. This article will focus on the exchange of information between the Single Resolution Board (SRB) and the European Central Bank (ECB). Firstly, the Authorities decided to arrange the rules for sharing information bilaterally in the form of a Memorandum of Understanding (MoU). While this framework of cooperation and exchange of information between the SRB and the ECB constitutes an obligation under Article 30(7) of the Single Resolution Mechanism Regulation (SRMR), it was drafted in the non-binding form of an MoU. The general purpose of an MoU is to establish the basis for cooperation and convergence of intentions. Such foundations aim to strengthen the resolution procedure by joining forces to obtain more accurate and complete data with better coordination of tasks and resources in order to achieve the most solid result possible within a tighter timeframe. [less ▲]

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See detailThe prestige and status of research fields within mathematics
Schlenker, Jean-Marc UL

E-print/Working paper (2020)

While the ``hierarchy of science'' has been widely analysed, there is no corresponding study of the status of subfields within a given scientific field. We use bibliometric data to show that subfields of ... [more ▼]

While the ``hierarchy of science'' has been widely analysed, there is no corresponding study of the status of subfields within a given scientific field. We use bibliometric data to show that subfields of mathematics have a different ``standing'' within the mathematics community. Highly ranked departments tend to specialize in some subfields more than in others, and the same subfields are also over-represented in the most selective mathematics journals or among recipients of top prizes. Moreover this status of subfields evolves markedly over the period of observation (1984--2016), with some subfields gaining and others losing in standing. The status of subfields is related to different publishing habits, but some of those differences are opposite to those observed when considering the hierarchy of scientific fields. We examine possible explanations for the ``status'' of different subfields. Some natural explanations -- availability of funding, importance of applications -- do not appear to function, suggesting that factors internal to the discipline are at work. We propose a different type of explanation, based on a notion of ``focus'' of a subfield, that might or might not be specific to mathematics. [less ▲]

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See detailWorking Document to support the EMN Inform: EU and OECD Member States responses to managing residence permits and migrant unemployment during the COVID-19 pandemic
Sommarribas, Adolfo UL; Sheridan, Anne

E-print/Working paper (2020)

The COVID-19 took by surprise most Member States of the European Union, as they underestimated the rapid spread of the contagion in the continent. The response of the Member States was asymmetrical ... [more ▼]

The COVID-19 took by surprise most Member States of the European Union, as they underestimated the rapid spread of the contagion in the continent. The response of the Member States was asymmetrical, individualistic and significantly slow. The first measures taken were to close down the internal borders. The response of the European Union was even slower to the point that and it was not until March 17th 2020 that the external borders were closed. These actions affected legal migration into the European Union from four perspectives: 1) it affected the mobility of those third country nationals who were on temporary stay in the Member States; 2) the entry of third country nationals to do seasonal work; 3) the entry and stay of legal migrants; and 4) the status quo of the third country nationals already residing in the Member States, especially those who have a loss of income. This article will deal with the measures taken by Member States on who to manage the immigration services during the crisis as well as the measures taken in order to deal with overstayers, seasonal workers and other legal migrants. Finally, we will focus in the vulnerable situation that third-country national salaried workers are exposed due to the loss of income or loss of employment in the Member States and the risk of being returned to their country of origin. [less ▲]

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See detailTesting informed SIR based epidemiological model for COVID-19 in Luxembourg
Sauter, Thomas UL; Pires Pacheco, Maria Irene UL

E-print/Working paper (2020)

The interpretation of the number of COVID-19 cases and deaths in a country or region is strongly dependent on the number of performed tests. We developed a novel SIR based epidemiological model (SIVRT ... [more ▼]

The interpretation of the number of COVID-19 cases and deaths in a country or region is strongly dependent on the number of performed tests. We developed a novel SIR based epidemiological model (SIVRT) which allows the country-specific integration of testing information and other available data. The model thereby enables a dynamic inspection of the pandemic and allows estimating key figures, like the number of overall detected and undetected COVID-19 cases and the infection fatality rate. As proof of concept, the novel SIVRT model was used to simulate the first phase of the pandemic in Luxembourg. An overall number of infections of 13.000 and an infection fatality rate of 1,3 was estimated, which is in concordance with data from population-wide testing. Furthermore based on the data as of end of May 2020 and assuming a partial deconfinement, an increase of cases is predicted from mid of July 2020 on. This is consistent with the current observed rise and shows the predictive potential of the novel SIVRT model. [less ▲]

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See detailPISTIS: From a Word-of-Mouth to a Gentleman’s Agreement
Kozhaya, David; Decouchant, Jérémie UL; Rahli, Vincent et al

E-print/Working paper (2020)

The accelerated digitalisation of society along with technological evolution have extended the geographical span of cyber-physical systems. Two main threats have made the reliable and real-time control of ... [more ▼]

The accelerated digitalisation of society along with technological evolution have extended the geographical span of cyber-physical systems. Two main threats have made the reliable and real-time control of these systems challenging: (i) uncertainty in the communication infrastructure induced by scale, openness and heterogeneity of the environment and devices; and (ii) targeted attacks maliciously worsening the impact of the above-mentioned communication uncertainties, disrupting the correctness of real-time applications. This paper addresses those challenges by showing how to build distributed protocols that provide both real-time with practical performance, and scalability in the presence of network faults and attacks. We provide a suite of real-time Byzantine protocols, which we prove correct, starting from a reliable broadcast protocol, called PISTIS, up to atomic broadcast and consensus. This suite simplifies the construction of powerful distributed and decentralized monitoring and control applications, including state-machine replication. Extensive empirical evaluations show- case PISTIS’s robustness, latency, and scalability. For example, PISTIS can withstand message loss (and delay) rates up to 40% in systems with 49 nodes and provides bounded delivery latencies in the order of a few milliseconds. [less ▲]

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See detailA mixed chamber or an ad hoc advisory body for the Court of Justice of the EU?
Zinonos, Panagiotis UL

E-print/Working paper (2020)

Detailed reference viewed: 29 (3 UL)
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See detailThe impact of Brexit on “bail-inable” liabilities under English law
Lupinu, Pier Mario UL

E-print/Working paper (2020)

Over three years have passed since 29 March 2017, the date when the United Kingdom (UK) triggered Article 50 of the Treaty on European Union (TEU). This date has become well-known, for paving the way to ... [more ▼]

Over three years have passed since 29 March 2017, the date when the United Kingdom (UK) triggered Article 50 of the Treaty on European Union (TEU). This date has become well-known, for paving the way to multiple legal issues, which mostly depend on the finalisation of an agreement setting the conditions for the future relations between the European Union (EU) and the UK. Despite recent political declarations, the Brexit outcome is now clear, and a transitional period has just begun. As a result, for the resolution of credit institutions established in the EU, the bail-in of liabilities previously established under English law could become problematic. To date, the EU framework for the resolution of credit institutions (namely, the Bank Recovery and Resolution Directive – BRRD) lacks a provision for the direct recognition of liabilities governed under third-country law. However, through its Article 55, the BRRD leaves to the EU Member State (MS) the duty to require entities to include “resolution-proof” clauses or, alternatively, to conclude a binding agreement with the relevant third country. This leaves a legislative gap concerning this direct recognition. By analysing the current EU legal framework for the bail-in of liabilities established with contracts governed by third-country law, with a view to identify its weaknesses, this paper aims at addressing possible practical solutions. The purpose is to ease the resolution process for the relevant administrative authority of the EU MS in charge of the resolution procedure, without the need of an immediate intervention of the legislator. Indeed, a solution for such gap in the BRRD might be disentangled outside the Brexit withdrawal agreement, or with specific arrangements between the EU/EU MS and the UK administrative authorities. [less ▲]

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See detailGenome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture
Chia, Ruth; Sabir, Marya S.; Bandres-Ciga, Sara et al

E-print/Working paper (2020)

The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed whole-genome sequencing in large cohorts of LBD cases and neurologically healthy controls to study the genetic ... [more ▼]

The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed whole-genome sequencing in large cohorts of LBD cases and neurologically healthy controls to study the genetic architecture of this understudied form of dementia and to generate a resource for the scientific community. Genome-wide association analysis identified five independent risk loci, whereas genome-wide gene-aggregation tests implicated mutations in the gene GBA. Genetic risk scores demonstrate that LBD shares risk profiles and pathways with Alzheimer’s and Parkinson’s disease, providing a deeper molecular understanding of the complex genetic architecture of this age-related neurodegenerative condition.Competing Interest StatementThomas G. Beach is a consultant for Prothena, Vivid Genomics and Avid Radiopharmaceuticals. He is a scientific advisory board member for Vivid Genomics. John A. Hardy, Huw R. Morris, Stuart Pickering-Brown, Andrew B. Singleton, and Bryan J. Traynor hold US, EU and Canadian patents on the clinical testing and therapeutic intervention for the hexanucleotide repeat expansion of C9orf72. Michael A. Nalls is supported by a consulting contract between Data Tecnica International and the National Institute on Aging, NIH, Bethesda, MD, USA; as a possible conflict of interest Dr. Nalls also consults for Neuron23 Inc., Lysosomal Therapeutics Inc., Illumina Inc., the Michael J. Fox Foundation and Vivid Genomics among others. Jose A. Palma is an editorial board member of Movement Disorders, Parkinsonism & Related Disorders, BMC Neurology, and Clinical Autonomic Research. Bradley F. Boeve, James Leverenz, and Sonja W. Scholz serve on the Scientific Advisory Council of the Lewy Body Dementia Association. Sonja W. Scholz is an editorial board member for the Journal of Parkinson's Disease. Bryan J. Traynor is an editorial board member for JAMA Neurology; Journal of Neurology, Neurosurgery, and Psychiatry; Brain; and Neurobiology of Aging. Zbigniew K. Wszolek serves as a principal investigator or co-principal investigator on Abbvie, Inc. (M15-562 and M15-563), Biogen, Inc. (228PD201) grant, and Biohaven Pharmaceuticals, Inc. (BHV4157-206 and BHV3241-301). Zbigniew K. Wszolek serves as the principal investigator of the Mayo Clinic American Parkinson Disease Association (APDA) Information and Referral Center, and as co-principal investigator of the Mayo Clinic APDA Center for Advanced Research. All other authors report no competing interests. [less ▲]

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See detailScattering theory for the Hodge-Laplacian
Baumgarth, Robert UL

E-print/Working paper (2020)

We prove using an integral criterion the existence and completeness of the wave operators corresponding to the Hodge-Laplacians acting on differential p-forms, induced by two quasi-isometric Riemannian ... [more ▼]

We prove using an integral criterion the existence and completeness of the wave operators corresponding to the Hodge-Laplacians acting on differential p-forms, induced by two quasi-isometric Riemannian metrics g and h on a complete open smooth manifold M. In particular, this result provides a criterion for the absolutely continuous spectra to coincide. The proof is based on gradient estimates obtained by probabilistic Bismut-type formulae for the heat semigroup defined by spectral calculus. By these localised formulae, the integral criterion only requires local curvature bounds and some upper local control on the heat kernel acting on functions, but no control on the injectivity radii. A consequence is a stability result of the absolutely continuous spectrum under a Ricci flow. As an application we concentrate on the important case of conformal perturbations. [less ▲]

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See detailConferences and international collaboration revisited in times of the coronavirus: Experiences from a digital transition and lessons for the future
Epping, Elisabeth UL; Lohse, Anna Prisca; Graf, Lukas et al

E-print/Working paper (2020)

"Everything was booked and ready to go for a two-day scientific workshop on education policies in Europe, scheduled for April 23-24, 2020 at the Hertie School in Berlin. The workshop intended to take ... [more ▼]

"Everything was booked and ready to go for a two-day scientific workshop on education policies in Europe, scheduled for April 23-24, 2020 at the Hertie School in Berlin. The workshop intended to take stock of developments at the European, national and sub-national levels given the European Union’s wrap up of its decade-long Education & Training 2020 strategy (ET 2020), a framework for cooperation in education and training. However, on March 12, we had to cancel the physical meeting on short notice due to the coronavirus crisis. In the following, we share our experiences with the subsequent transition to an alternative online workshop format that took place on April 23, involving 25 participants from 10 countries, and 16 paper presentations. After sketching the workshop’s virtual setup, we discuss strengths, weaknesses, and challenges related to this digital transition. Furthermore, we explore the prospects of such online formats for future academic conferences and networking." [less ▲]

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See detailQuantifying the role of mechanics in the free and encapsulated growth of cancer spheroids
Urcun, Stéphane UL

E-print/Working paper (2020)

Mechanics is of primordial importance to understand cancer; hence, experimental and mathematical models providing quantitative information and play a pivotal role on the development of new therapies ... [more ▼]

Mechanics is of primordial importance to understand cancer; hence, experimental and mathematical models providing quantitative information and play a pivotal role on the development of new therapies. Within this context, encapsulated spheroids are emerging as exceptional in vitro tools to investigate the impact of mechanical forces on tumor growth, since from the deformation of the alginate capsule the internal pressure can be retrieved. We show that bio-chemo-poro-mechanics is a suitable theoretical framework to understand, explain and design these in vitro experiments. Such mechanistic models are based on a set of coupled partial differential equations solved within an open-source framework (FEniCS). Through sensitivity analyses, our mathematical model suggests that the main parameters determining the encapsulated and free growth configurations are independent, this observation indicates that radically different phenomena are at play. This demonstrates potentialities of reactive porous media mechanics in oncophysics and can serve to supplement in vivo clinical data. [less ▲]

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See detailTravail frontalier et fermeture des frontières : l’exemple de la Grande Région SaarLorLux
Pigeron-Piroth, Isabelle UL; Evrard, Estelle UL; Belkacem, rachid

E-print/Working paper (2020)

La crise sanitaire provoquée par la pandémie de COVID-19 a imposé d’importantes adaptations au marché du travail transfrontalier dans la Grande Région SaarLorLux. Les mesures prises pour éviter la ... [more ▼]

La crise sanitaire provoquée par la pandémie de COVID-19 a imposé d’importantes adaptations au marché du travail transfrontalier dans la Grande Région SaarLorLux. Les mesures prises pour éviter la propagation de la maladie imposent de limiter les déplacements au strict minimum tandis que l’efficience des services de santé publics impose la proximité. Ces mesures, qui se sont rapidement imposées aux acteurs publics, aux entreprises et aux individus, questionnent directement le fonctionnement d’un marché du travail transfrontalier structuré par la mobilité transfrontalière. Afin de maintenir tant que possible les activités économiques et de pourvoir aux besoins sanitaires, les exécutifs nationaux ont adapté les fonctions de la frontière. [less ▲]

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See detailDeep sncRNA-seq of the PPMI cohort to study Parkinson’s disease progression
Kern, Fabian; Fehlmann, Tobias; Violich, Ivo et al

E-print/Working paper (2020)

Coding and non-coding RNAs have diagnostic and prognostic importance in Parkinson’s diseases (PD). We studied circulating small non-coding RNAs (sncRNAs) in 7, 003 samples from two longitudinal PD cohorts ... [more ▼]

Coding and non-coding RNAs have diagnostic and prognostic importance in Parkinson’s diseases (PD). We studied circulating small non-coding RNAs (sncRNAs) in 7, 003 samples from two longitudinal PD cohorts (Parkinson’s Progression Marker Initiative (PPMI) and Luxembourg Parkinson’s Study (NCER-PD)) and modelled their influence on the transcriptome. First, we sequenced sncRNAs in 5, 450 blood samples of 1, 614 individuals in PPMI. The majority of 323 billion reads (59 million reads per sample) mapped to miRNAs. Other covered RNA classes include piRNAs, rRNAs, snoRNAs, tRNAs, scaRNAs, and snRNAs. De-regulated miRNAs were associated with the disease and disease progression and occur in two distinct waves in the third and seventh decade of live. Originating mostly from a characteristic set of immune cells they resemble a systemic inflammation response and mitochondrial dysfunction, two hallmarks of PD. By profiling 1, 553 samples from 1, 024 individuals in the NCER-PD cohort using an independent technology, we validate relevant findings from the sequencing study. Finally, network analysis of sncRNAs and transcriptome sequencing of the original cohort identified regulatory modules emerging in progressing PD patients.Competing Interest StatementThe authors have declared no competing interest. [less ▲]

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See detailEthnocentric preferences and the environment with international trade
Zanaj, Skerdilajda UL

E-print/Working paper (2020)

We define a model of international trade with two countries, two vertically differentiated goods, and heterogenous consumers concerning their willingness to pay for quality. Trade generates two sources of ... [more ▼]

We define a model of international trade with two countries, two vertically differentiated goods, and heterogenous consumers concerning their willingness to pay for quality. Trade generates two sources of pollution: the production of domestic and traded goods, and their transportation between countries. Consumers in both countries manifest home bias which translates into ethnocentric preferences: (i) consumer perceive the quality of the domestic good amplified; and (ii) consumers thrive additional satisfaction when consuming a domestic good rather than a foreign one since only the former can satisfy their sense of place. By contrast, they suffer a psychological penalty when consuming a foreign product. We investigate the role of trade costs and ethnocentric attitude in shaping the equilibrium configuration of the international duopoly. Finally, we uncover the environmental damage from production and from transport in presence of ethnocentrism. [less ▲]

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See detailBending laminations on convex hulls of anti-de Sitter quasicircles
merlin, louis; Schlenker, Jean-Marc UL

E-print/Working paper (2020)

Let λ− and λ+ be two bounded measured laminations on the hyperbolic disk H2, which "strongly fill" (definition below). We consider the left earthquakes along λ− and λ+, considered as maps from the ... [more ▼]

Let λ− and λ+ be two bounded measured laminations on the hyperbolic disk H2, which "strongly fill" (definition below). We consider the left earthquakes along λ− and λ+, considered as maps from the universal Teichmüller space T to itself, and we prove that the composition of those left earthquakes has a fixed point. The proof uses anti-de Sitter geometry. Given a quasi-symmetric homeomorphism u:RP1→RP1, the boundary of the convex hull in AdS3 of its graph in RP1×RP1≃∂AdS3 is the disjoint union of two embedded copies of the hyperbolic plane, pleated along measured geodesic laminations. Our main result is that any pair of bounded measured laminations that "strongly fill" can be obtained in this manner. [less ▲]

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See detailAttitudes towards Multiculturalism in Luxembourg: Measurement Invariance and Factor Structure of the Multicultural Ideology Scale
Stogianni, Maria UL; Murdock, Elke UL; He, Jia et al

E-print/Working paper (2020)

The present study examined the dimensionality and the measurement invariance of the Multicultural Ideology Scale (MCI; Berry & Kalin, 1995), and mean differences across different cultural groups within ... [more ▼]

The present study examined the dimensionality and the measurement invariance of the Multicultural Ideology Scale (MCI; Berry & Kalin, 1995), and mean differences across different cultural groups within the multilingual, multicultural context of Luxembourg. With 47% of the citizens being non-nationals, minority and majority are increasingly difficult to define and Luxembourg becomes a unique context to study attitudes towards diversity. Our sample included 1488 participants from diverse ethnic backgrounds who completed the survey in German, French or English. In contrast to previous findings, our analyses revealed a two-dimensional structure, distinguishing between positive and negative attitudes towards multiculturalism. The factor structure was partially invariant across ethnocultural groups: Configural and metric invariance were established across natives and non-natives, scalar invariance only across gender groups. Natives and male participants reported more negative attitudes towards multiculturalism. We discuss the importance of assessing measurement invariance and provide recommendations to improve the assessment of psychological multiculturalism. [less ▲]

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See detailPriLok:Citizen-protecting distributed epidemic tracing
Esteves-Verissimo, Paulo UL; Decouchant, Jérémie UL; Volp, Marcus UL et al

E-print/Working paper (2020)

Contact tracing is an important instrument for national health services to fight epidemics. As part of the COVID-19 situation, many proposals have been made for scaling up contract tracing capacities with ... [more ▼]

Contact tracing is an important instrument for national health services to fight epidemics. As part of the COVID-19 situation, many proposals have been made for scaling up contract tracing capacities with the help of smartphone applications, an important but highly critical endeavor due to the privacy risks involved in such solutions. Extending our previously expressed concern, we clearly articulate in this article, the functional and non-functional requirements that any solution has to meet, when striving to serve, not mere collections of individuals, but the whole of a nation, as required in face of such potentially dangerous epidemics. We present a critical information infrastructure, PriLock, a fully-open preliminary architecture proposal and design draft for privacy preserving contact tracing, which we believe can be constructed in a way to fulfill the former requirements. Our architecture leverages the existing regulated mobile communication infrastructure and builds upon the concept of "checks and balances", requiring a majority of independent players to agree to effect any operation on it, thus preventing abuse of the highly sensitive information that must be collected and processed for efficient contact tracing. This is enforced with a largely decentralised layout and highly resilient state-of-the-art technology, which we explain in the paper, finishing by giving a security, dependability and resilience analysis, showing how it meets the defined requirements, even while the infrastructure is under attack. [less ▲]

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See detailBehind the Last Line of Defense -- Surviving SoC Faults and Intrusions
Pinto Gouveia, Ines UL; Volp, Marcus UL; Esteves-Verissimo, Paulo UL

E-print/Working paper (2020)

Today, leveraging the enormous modular power, diversity and flexibility of manycore systems-on-a-chip (SoCs) requires careful orchestration of complex resources, a task left to low-level software, e.g ... [more ▼]

Today, leveraging the enormous modular power, diversity and flexibility of manycore systems-on-a-chip (SoCs) requires careful orchestration of complex resources, a task left to low-level software, e.g. hypervisors. In current architectures, this software forms a single point of failure and worthwhile target for attacks: once compromised, adversaries gain access to all information and full control over the platform and the environment it controls. This paper proposes Midir, an enhanced manycore architecture, effecting a paradigm shift from SoCs to distributed SoCs. Midir changes the way platform resources are controlled, by retrofitting tile-based fault containment through well known mechanisms, while securing low-overhead quorum-based consensus on all critical operations, in particular privilege management and, thus, management of containment domains. Allowing versatile redundancy management, Midir promotes resilience for all software levels, including at low level. We explain this architecture, its associated algorithms and hardware mechanisms and show, for the example of a Byzantine fault tolerant microhypervisor, that it outperforms the highly efficient MinBFT by one order of magnitude. [less ▲]

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See detailInteractive MS/MS Visualization with the Metabolomics Spectrum Resolver Web Service
Wang, Mingxun; Rogers, Simon; Bittremieux, Wout et al

E-print/Working paper (2020)

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See detailBoîte à outils pour la formation des enseignants
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Dans le cadre du projet BMC-EU (Compétences motrices de base en Europe), une boîte à outils pour la formation des enseignants reprenant le concept de formation ainsi qu’un manuel d'utilisation (BMC-EU ... [more ▼]

Dans le cadre du projet BMC-EU (Compétences motrices de base en Europe), une boîte à outils pour la formation des enseignants reprenant le concept de formation ainsi qu’un manuel d'utilisation (BMC-EU production intellectuelle 4) a été développée afin de soutenir la mise en œuvre de la formation aux tests MOBAK (boîte à outils pour l’enseignant-support théorique) la base du concept de compétences motrices de base (BMC-EU production intellectuelle 3 ; Scheuer & Heck, 2020). L'objectif de cette boîte à outils de soutien est d'être mis en œuvre principalement au niveau des cours réguliers d'éducation physique pour aider les enseignants d’éducation physique à adapter leurs contenus et leurs méthodes d'enseignement. La boîte à outils pour la formation des enseignants présente les éléments à mettre en œuvre lors de formations d'enseignants. Celles-ci sont structurées en une partie théorique et une partie pratique. Dans un premier temps, les enseignants sont familiarisés avec le concept MOBAK, la mesure, la procédure de test, le traitement des données et l’évaluation ainsi qu'avec l'interprétation des résultats du test. Dans une deuxième partie, ils apprennent à passer du diagnostic des compétences motrices de base des élèves et des forces et faiblesses identifiées dans l'évaluation à des interventions concrètes en utilisant le cadre de soutien MOBAK et les documents qui l'accompagnent sous la forme d'un support théorique (boîte à outils pour l’enseignant), prêt à être mis en œuvre dans des situations éducatives concrètes pour soutenir les élèves ayant des besoins supplémentaires en compétences motrices de base. Étant donné que la boîte à outils pour la formation des enseignants vise à soutenir et à faciliter la mise en œuvre de la formation théorique des enseignants de soutien modulaire pour les enseignants (Scheuer et Heck, 2020), il sera fait référence au concept et au construit des tests MOBAK (Herrmann, 2018), et au manuel de test MOBAK tout au long de ce document. [less ▲]

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See detailToolkit voor de brede motorische ontwikkeling
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

In het kader van het BMC-EU-project (Basismotorische competentie in Europa) is een toolkit voor de training van docenten en een toolkit voor de brede motorische ontwikkeling ontwikkeld. Dit is ontwikkeld ... [more ▼]

In het kader van het BMC-EU-project (Basismotorische competentie in Europa) is een toolkit voor de training van docenten en een toolkit voor de brede motorische ontwikkeling ontwikkeld. Dit is ontwikkeld op basis van het concept basismotorische competenties en de resultaten van de gegevensverzameling in fase 1 van het project als onderdeel van intellectuele output 3. Het doel van deze toolkit is om de inhoud en methoden van de reguliere lessen lichamelijke opvoeding aan te passen aan de (motorische) behoeften van de kinderen. In een eerste stap is het hulpaanbod ontwikkeld. Dit is ontwikkeld op basis van de diagnose van de motorische basiscompetenties van de kinderen en de sterke en zwakke punten die bij de beoordeling zijn geïdentificeerd. Dit vormde het raamwerk voor de ondersteunende hand-outs in deze toolkit. De toolkit kan direct geïmplementeerd worden in concrete onderwijssituaties. Kinderen met aanvullende behoeften in basismotorische competenties kunnen hiermee worden ondersteund. De toolkit bevat verschillende onderdelen: - Richtlijnen voor de interpretatie van MOBAK-testresultaten (Motorische Basiskompetenzen; Duits voor basismotorische competenties). - De MOBAK-toolkit. - Een verklarende woordenlijst. - De modulaire supporttoolkit met materiaal voor leraren lichamelijke opvoeding in de vorm van MOBAK activiteiten-kaarten. - MOBAK-activiteitenkaarten gebaseerd op variatieprincipes en op een competentiegerichte aanpak. [less ▲]

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See detailΕργαλειοθήκη κατάρτισης για εκπαιδευτικούς
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Στο πλαίσιο του έργου BMC-EU (Βασικές Κινητικές Δεξιότητες στην Ευρώπη), αναπτύχθηκε μία εργαλειοθήκη κατάρτισης για εκπαιδευτικούς, αποτελούμενη από τη γενική πρακτική ιδέα και ένα συνοδευτικό εγχειρίδιο ... [more ▼]

Στο πλαίσιο του έργου BMC-EU (Βασικές Κινητικές Δεξιότητες στην Ευρώπη), αναπτύχθηκε μία εργαλειοθήκη κατάρτισης για εκπαιδευτικούς, αποτελούμενη από τη γενική πρακτική ιδέα και ένα συνοδευτικό εγχειρίδιο χρήστη (BMC-EU πνευματική παραγωγή 4), για να υποστηρίξει την εφαρμογή της υποστηρικτικής εργαλειοθήκης με βάση την έννοια των βασικών κινητικών δεξιοτήτων (BMC-EU πνευματική παραγωγή 3; Scheuer & Heck, 2020). Ο σκοπός της εργαλειοθήκης αυτής είναι να εφαρμοστεί στα μαθήματα φυσικής αγωγής, ώστε να προσαρμοστούν κατάλληλα τόσο το περιεχόμενο όσο και οι μέθοδοι διδασκαλίας της φυσικής αγωγής. Η εργαλειοθήκη κατάρτισης για εκπαιδευτικούς περιέχει υλικό για τη δημιουργία πρακτικών προγραμμάτων για εκπαιδευτικούς δομημένα τόσο σε θεωρητικό, όσο και πρακτικό επίπεδο. Αρχικά, οι εκπαιδευτικοί εξοικειώνονται με την έννοια του ΜΟΒΑΚ, τις μετρήσεις, τη διαδικασία της εξέτασης, την επεξεργασία των δεδομένων και την αξιολόγηση, καθώς και με την ερμηνεία των αποτελεσμάτων. Στη συνέχεια, μαθαίνουν πώς να μεταβούν από τη διάγνωση των βασικών κινητικών δεξιοτήτων και τον εντοπισμό των αντίστοιχων ικανοτήτων των μαθητών, στον σχεδιασμό και την υλοποίηση συγκεκριμένων παρεμβάσεων με τη χρήση του υποστηρικτικού πλαισίου ΜΟΒΑΚ και των συνοδευτικών υποστηρικτικών φυλλαδίων, που είναι έτοιμα προς εφαρμογή σε συγκεκριμένες εκπαιδευτικές συνθήκες για την υποστήριξη μαθητών με πρόσθετες ανάγκες στις βασικές κινητικές δεξιότητες. Η εργαλειοθήκη κατάρτισης για εκπαιδευτικούς έχει ως σκοπό να υποστηρίξει και να διευκολύνει την εφαρμογή της Υποστηρικτικής εργαλειοθήκης για εκπαιδευτικούς (Scheuer & Heck, 2020), που βασίζεται στην έννοια και τις μετρήσεις ΜΟΒΑΚ (Herrmann, 2018). [less ▲]

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See detailMokytojų rengimo priemonė
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Vykdant BMC-EU projektą "Basic motor competencies in Europe" buvo sukurta mokytojų rengimo priemonė, susidedanti iš mokytojų rengimo sampratos ir vartotojo vadovo (BMC-EU intelektinės veiklos rezultatas ... [more ▼]

Vykdant BMC-EU projektą "Basic motor competencies in Europe" buvo sukurta mokytojų rengimo priemonė, susidedanti iš mokytojų rengimo sampratos ir vartotojo vadovo (BMC-EU intelektinės veiklos rezultatas Nr. 4), kurios tikslas - remiantis motorinių kompetencijų koncepcija padėti įgyvendinti modulinę palaikymo priemonę (BMC-EU intelektinės veiklos rezultatas Nr. 3; Scheuer ir Heck, 2020). Palaikymo priemonė skirta įprastoms kūno kultūros pamokoms, kurių metu skatinami turinio ir metodų pokyčiai ir jų taikymai. Mokytojų rengimo priemonėje pateikiama teorinė ir praktinė medžiaga. Pirmiausia mokytojai supažindinami su MOBAK koncepcija, matavimais, testavimo procedūra, duomenų apdorojimu ir vertinimu bei rezultatų aiškinimu. Antroje dalyje paaiškinama, kaip turimas žinias apie pagrindines moksleivių motorines kompetencijas ir vertinant išryškėjusias jų stipriąsias bei silpnąsias puses panaudoti praktiškai taikant MOBAK paramos sistemą ir kitą pagalbinę medžiagą konkrečiose mokymo situacijose atsižvelgiant į moksleivių poreikius ir pagrindines motorines kompetencijas. Kadangi mokytojų rengimo priemone siekiama palengvinti modulinės palaikymo priemonės mokytojams (Scheuer & Heck, 2020) įgyvendinimą remiantis MOBAK koncepcija ir matavimais (Herrmann, 2018), leidinyje dažnai mnima paramos sistema ir MOBAK vadovas. [less ▲]

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See detailToolkit für die Fortbildung von Sportlehrkräften
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Im Rahmen des BMC-EU Projekts (Basic Motor Competencies in Europe) wurde ein Toolkit für die Fortbildung von Sportlehrkräften entwickelt, welches aus einem Fortbildungskonzept inklusive eines Handbuchs ... [more ▼]

Im Rahmen des BMC-EU Projekts (Basic Motor Competencies in Europe) wurde ein Toolkit für die Fortbildung von Sportlehrkräften entwickelt, welches aus einem Fortbildungskonzept inklusive eines Handbuchs (BMC-EU intellectual output 4) besteht. Die Entwicklung dieses Fortbildungskonzepts soll dazu beitragen, dass das modulare Support Toolkit auf der Basis des Konzepts der motorischen Basiskompetenzen (BMC-EU intellectual output 3; Scheuer & Heck, 2020) eingesetzt wird. Das Ziel dieses Support Toolkits ist hauptsächlich der Einsatz auf der Ebene des regulären Sportunterrichts um die Anpassungen, welche den Inhalt und die Methoden des Unterrichtens betreffen, voranzutreiben. Das Toolkit für die Fortbildung von Lehrkräften beinhaltet Materialen, die für die Durchführung einer strukturierten Lehrerfortbildung sowohl im theoretischen als auch im praktischen Teil benötigt werden. Im ersten Schritt werden die Lehrkräfte mit dem MOBAK Konzept, der Datenerhebung, der Testdurchführung, der Datenverarbeitung und –evaluation sowie mit der Interpretation der Testergebnisse vertraut gemacht. Im zweiten Schritt lernen die Lehrkräfte wie sie auf die Stärken und Schwächen ihrer Schülerinnen und Schüler, welche die Ergebnisse aus den Tests zu den motorischen Basiskompetenzen zeigen, fördern können, indem sie das MOBAK Support Toolkit verwenden. Dieses Toolkit kann direkt in konkrete Unterrichtsszenarien eingesetzt werden, um die Schülerinnen und Schüler mit zusätzlichem Förderbedarf in den motorischen Kompetenzen zu unterstützen. Da das Toolkit für die Fortbildung von Lehrkräfte darauf abzielt, die Durchführung des modularen Support Toolkits für Lehrkräfte (Scheuer & Heck, 2020) basierend auf dem MOBAK Konzept (Herrmann, 2018) zu unterstützen und zu ermöglichen, wird in diesem Dokument immer wieder auf das Support Toolkit und das MOBAK Testmanual verwiesen. [less ▲]

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See detailVzorová sada podpůrných nástrojů pro učitele
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

V rámci projektu BMC-EU (Základní pohybové kompetence v Evropě) byl na základě koncepce základních pohybových kompetencí a výsledků sběru dat vytvořen rámec podpory a vzorová sada nástrojů (výsledek první ... [more ▼]

V rámci projektu BMC-EU (Základní pohybové kompetence v Evropě) byl na základě koncepce základních pohybových kompetencí a výsledků sběru dat vytvořen rámec podpory a vzorová sada nástrojů (výsledek první fáze projektu – intelektuální výstup 3). Účelem této sady je nabídnout variabilní přístup k metodice tělesné výchovy. V první fázi projektu byl vytvořen podpůrný rámec pro diagnostiku základních pohybových kompetencí žáků, jejich silných a slabých stránek z pohledu základních pohybových způsobilostí. Na základě tohoto rámce byly vyvinuty podklady ve formě vzorové podpůrné sady (didaktických) materiálů, připravených k implementaci v konkrétních vzdělávacích situacích, jejichž účelem je rozvoj základních pohybových kompetencí diagnostikovaných žáků. Vzorová podpůrná sada nástrojů obsahuje pokyny pro interpretaci výsledků testů MOBAK (Motorische Basiskompetenzen), podpůrný rámec MOBAK, glosář a vzorovou podpůrnou sadu nástrojů s materiály pro učitele tělesné výchovy ve formě karet MOBAK. Karty MOBAK popisují činnosti a aktivity dle principů variace (rozličnosti podnětů) a jsou založeny na přístupu orientovaném na kompetence. [less ▲]

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See detailFerramenta de apoio à Formação de Professores
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

No enquadramento do projeto BMC-EU (Competências motoras básicas na Europa), a ferramenta para a formação de professores consistindo num conceito de formação de professores juntamente com um manual de ... [more ▼]

No enquadramento do projeto BMC-EU (Competências motoras básicas na Europa), a ferramenta para a formação de professores consistindo num conceito de formação de professores juntamente com um manual de utilização (BMC-EU intellectual output 4) foi desenvolvido de modo a apoiar a implementação do kit modular de ferramentas para suporte aos professores considerando o conceito de competências motoras básicas (BMC-EU intellectual output 3; Scheuer & Heck, 2020). O objetivo deste kit de ferramentas de suporte é ser implementado principalmente ao nível da educação física regular para iniciar adaptações relativas ao conteúdo e métodos na instrução da educação física. A ferramenta de apoio à formação de professores contém materiais para implementar a formação de professores estruturada, com uma parte teórica e outra prática. Num primeiro passo, os professores estão familiarizados com o conceito MOBAK, medição, procedimentos do teste, tratamento dos dados e avaliação assim como com a interpretação dos resultados do teste. Numa segunda parte eles aprendem como diagnosticar as competências motoras básicas dos alunos e as forças e fraquezas identificadas na avaliação para concretizar intervenções usando o quadro de referência de suporte MOBAK e as fichas que acompanham o Kit de suporte, prontos para serem implementados em situações educativas concretas para apoiar estudantes com necessidades acrescidas nas competências motoras básicas. Como a ferramenta para a formação de professores visa apoiar e facilitar a implementação do Kit modular de ferramentas para suporte aos professores (Scheuer & Heck, 2020) baseado no conceito e medição do MOBAK (Herrmann, 2018), ao longo deste manual são fornecidas referências para suportar o kit de apoio e o manual do teste MOBAK . [less ▲]

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See detailKit modular de ferramentas para suporte aos professores
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

No quadro do projeto BMC-EU (Competências motoras básicas na Europa), foi desenvolvida um kit modular de ferramentas de suporte para os professores para o desenvolvimento das competências motoras básicas ... [more ▼]

No quadro do projeto BMC-EU (Competências motoras básicas na Europa), foi desenvolvida um kit modular de ferramentas de suporte para os professores para o desenvolvimento das competências motoras básicas, baseado nos resultados da colheita de dados realizada na fase 1 do projeto, como parte do seu output intelectual 3. O objetivo deste kit de ferramentas é ser implementado principalmente ao nível das aulas regulares de Educação Física, para apoiar as decisões dos professores em relação ao conteúdo e aos métodos no ensino de Educação Física. Numa primeira etapa, a estrutura de suporte foi desenvolvida para permitir avaliar e realizar o diagnóstico das competências motoras básicas dos alunos nos seus pontos fortes e fracos, e apoiar intervenções concretas. Como base dessa estrutura, foram desenvolvidos folhetos de suporte sob a forma de um kit modular de ferramentas de suporte, prontos para serem implementados em situações educacionais concretas, para apoiar o desenvolvimento de algumas competências básicas dos alunos. O kit modular de ferramentas de suporte inclui as diretrizes para a interpretação dos resultados dos testes MOBAK (Motorische Basiskompetenzen; expressão alemã para competências motoras básicas), que são a estrutura de suporte do MOBAK, um glossário, bem como o kit modular de ferramentas de suporte com materiais para professores de Educação Física sob a forma de cartões com a descrição das tarefas do forma de MOBAK e de cartões de atividade MOBAK baseados em princípios da variação e de uma abordagem por competências. [less ▲]

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See detailSada nástrojů pro školení učitelů
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

V rámci projektu BMC-EU (Základní pohybové kompetence v Evropě) byla vyvinuta sada nástrojů pro školení učitelů, skládající se z koncepce školení učitelů a doprovodné uživatelské příručky (intelektuální ... [more ▼]

V rámci projektu BMC-EU (Základní pohybové kompetence v Evropě) byla vyvinuta sada nástrojů pro školení učitelů, skládající se z koncepce školení učitelů a doprovodné uživatelské příručky (intelektuální výstup BMC-EU 4) za účelem podpory implementace modulární podpůrné sady nástrojů na základě konceptu základních pohybových kompetencí (intelektuální výstup BMC-EU 3; Scheuer & Heck, 2020). Cílem této podpůrné sady nástrojů je zavedení do praxe především na úrovni pravidelných hodin tělesné výchovy tak, aby bylo možno začít s přizpůsobováním obsahu a metod výuky tělesné výchovy. Sada nástrojů pro školení učitelů obsahuje materiály pro realizaci školení rozdělené do teoretické a praktické části. V první části jsou učitelé seznámeni s konceptem MOBAK, měřením, testovacím postupem, zpracováním a vyhodnocováním dat a s interpretací výsledků testů. Ve druhé části se naučí, jak dospět od diagnostiky základních pohybových kompetencí studentů a od silných a slabých stránek identifikovaných při hodnocení k tomu, jak konkrétně zasáhnout pomocí podpůrného rámce MOBAK a doprovodných podpůrných materiálů ve formě modulární podpůrné sady nástrojů, která je připravena k zavádění do praxe v konkrétních vzdělávacích situacích za účelem podpory studentů s dalšími potřebami v základních pohybových kompetencích. Vzhledem k tomu, že sada nástrojů pro školení učitelů má za cíl podporovat a usnadňovat implementaci Modulární podpůrné sady pro učitele (Scheuer & Heck, 2020) založenou na konceptu a měření MOBAK (Herrmann, 2018), v celém tomto dokumentu se na podpůrnou sadu nástrojů a na testovací příručku MOBAK odkazuje. [less ▲]

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See detailManuale di formazione per gli insegnanti
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Nell’ambito del progetto BMC-EU (Competenze motorie di base in Europa), è stato sviluppato un ulteriore documento utile alla formazione degli insegnanti, che consiste in un manuale di formazione (output ... [more ▼]

Nell’ambito del progetto BMC-EU (Competenze motorie di base in Europa), è stato sviluppato un ulteriore documento utile alla formazione degli insegnanti, che consiste in un manuale di formazione (output intellettuale BMC-EU 4), al fine di implementare il manuale modulare riguardante le competenze motorie di base (produzione intellettuale BMC-EU 3; Scheuer & Heck, 2020). Lo scopo di questo manuale è quello di ampliare i contenuti delle lezioni curriculari di educazione fisica, per proporre gli adattamenti riguardanti le attività ed i metodi. Il manuale contiene i materiali per implementare il processo di formazione degli insegnanti ed è strutturato in una parte teorica e una pratica. In una prima parte, gli insegnanti acquisiscono familiarità con la struttura del MOBAK, la misurazione, l’attuazione delle prove, l’elaborazione e e la valutazione dei dati, nonché con l'interpretazione dei risultati delle prove. In una seconda parte, imparano ad acquisire informazioni sulle competenze motorie di base degli allievi e sui punti di forza e di debolezza identificati nella valutazione. Inoltre, mediante proposte operative presenti nel manuale modulare del MOBAK e negli allegati, è possibile implementare i contesti di apprendimento per sostenere gli allievi con bisogni educativi speciali nelle competenze motorie di base. Il presente manuale per la formazione degli insegnanti è finalizzato a sostenere ed integrare il manuale modulare (Scheuer & Heck, 2020), basato sulla struttura e sui livelli del MOBAK (Herrmann, 2018). [less ▲]

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See detailToolkit voor de training van docenten
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

In het kader van het BMC-EU project (Basismotorische competenties in Europa) heeft men op basis van het concept van basismotorische competenties (BMC-EU intellectuele output), een toolkit voor de training ... [more ▼]

In het kader van het BMC-EU project (Basismotorische competenties in Europa) heeft men op basis van het concept van basismotorische competenties (BMC-EU intellectuele output), een toolkit voor de training van docenten ontwikkeld met daarbij een bijbehorende gebruikershandleiding. Het doel van deze toolkit is voornamelijk om op het niveau van de reguliere lessen lichamelijke opvoeding aanpassingen te initiëren die van toepassing zijn op de inhoud en methoden in de lichamelijke opvoeding. De training voor docenten is opgedeeld in een praktisch en theoretisch deel. Allereerst worden leraren vertrouwd gemaakt met het MOBAK concept, de meting, testprocedure, de gegevensverwerking en evaluatie, evenals met de interpretatie van de testresultaten. In een tweede deel leren ze hoe ze van de diagnose van de basismotorische competenties van studenten en de sterke en zwakke punten die bij de beoordeling zijn geïdentificeerd, kunnen komen tot concrete interventies. Dit kan door het MOBAK kader en de bijbehorende hand-outs te gebruiken in de vorm van een modulaire ondersteunende toolkit. Deze toolkit kan ingezet worden in concrete onderwijssituaties om kinderen met aanvullende behoeften in basismotorische competenties te ondersteunen. Aangezien de training voor docenten de uitvoering van de toolkit voor de brede motorische ontwikkeling (Scheuer & Heck, 2020), gebaseerd op het MOBAK-concept en meting (Herrmann, 2018), wil ondersteunen en vergemakkelijken, wordt in dit document verwezen naar de ondersteunende toolkit en de MOBAK-testhandleiding. [less ▲]

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See detailNástroj pre školenie učiteľov
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

V rámci projektu BMC-EU (Základné pohybové kompetencie v Európe) bol vytvorený súbor nástrojov odbornej prípravy učiteľov pozostávajúci z koncepcie odbornej prípravy učiteľov so sprievodným návodom na ... [more ▼]

V rámci projektu BMC-EU (Základné pohybové kompetencie v Európe) bol vytvorený súbor nástrojov odbornej prípravy učiteľov pozostávajúci z koncepcie odbornej prípravy učiteľov so sprievodným návodom na použitie (intelektuálny výstup BMC-EU 4), s cieľom podporiť využitie podporného metodického materiálu na základe koncepcie základných pohybových kompetencií (intelektuálny výstup BMC-EU 3; Scheuer & Heck, 2020). Cieľom tohto podporného materiálu je iniciovať na úrovni pravidelných hodín telesnej a športovej výchovy úpravy týkajúce sa obsahu a metód výučby telesnej a športovej výchovy. Nástroj pre školenie učiteľov obsahuje materiály na realizáciu školení učiteľov štruktúrovaných v teoretickej a praktickej časti. V prvom kroku sú učitelia oboznámení s koncepciou MOBAK, meraním, testovacím postupom, spracovaním a vyhodnotením údajov, ako aj s interpretáciou výsledkov testov. V druhej časti sa naučia, ako získať informácie z diagnostiky základných pohybových kompetencií žiakov a ich silných a slabých stránok identifikovaných pri hodnotení. Tiež sa naučia pracovať s pomocou podporného rámca MOBAK a sprievodných podporných nástrojov vo forme podpornej metodickej príručky, pripravenej na implementáciu v konkrétnych vzdelávacích situáciách na podporu žiakov s ďalšími potrebami v základných pohybových kompetenciách. Keďže cieľom súboru nástrojov prípravy učiteľov je podporiť a uľahčiť implementáciu metodickej príručky pre učiteľov (Scheuer & Heck, 2020) založenej na koncepte a meraní MOBAK (Herrmann, 2018), odkaz na podpornú metodickú príručku MOBAK je uvedený v tomto dokumente. [less ▲]

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See detailTeacher training toolkit
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

In the frame of the BMC-EU project (Basic motor competencies in Europe), a teacher training toolkit consisting of a teacher training concept with an accompanying user manual (BMC-EU intellectual output 4 ... [more ▼]

In the frame of the BMC-EU project (Basic motor competencies in Europe), a teacher training toolkit consisting of a teacher training concept with an accompanying user manual (BMC-EU intellectual output 4) was developed in order to support the implementation of the modular support toolkit on the basis of the concept of basic motor competences (BMC-EU intellectual output 3; Scheuer & Heck, 2020). The aim of this support toolkit is to be implemented mainly at the level of regular physical education lessons to initiate adaptations regarding the content and methods in physical education instruction. The teacher training toolkit contains materials to implement teacher trainings structured in a theoretical and a practical part. In a first step, teachers are familiarized with the MOBAK concept, measurement, test procedure, data procession and evaluation as well as with the interpretation of test results. In a second part, they learn how to get from the diagnosis of the students’ basic motor competencies and the strengths and weaknesses identified in the assessment to concrete interventions by using the MOBAK support framework and the accompanying supportive handouts in form of a modular support toolkit, ready to be implemented in concrete educational situations to support students with additional needs in basic motor competencies. As the teacher training toolkit aims to support and facilitate the implementation of the Modular support toolkit for teachers (Scheuer & Heck, 2020) based on the MOBAK concept and measurement (Herrmann, 2018), reference to the support toolkit and the MOBAK Test manual is given throughout this document [less ▲]

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See detailPrimary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine
Golebiewska, Anna UL; Hau, Ann-Christin; Oudin, Anais et al

E-print/Working paper (2020)

Patient-derived cancer models are essential tools for studying tumor biology and preclinical interventions. Here, we show that glioma patient-derived orthotopic xenografts (PDOXs) enable long-term ... [more ▼]

Patient-derived cancer models are essential tools for studying tumor biology and preclinical interventions. Here, we show that glioma patient-derived orthotopic xenografts (PDOXs) enable long-term propagation of patient tumors and represent clinically relevant patient avatars. We created a large collection of PDOXs from primary and recurrent gliomas with and without mutations in IDH1, which retained histopathological, genetic, epigenetic and transcriptomic features of patient tumors with no mouse-specific clonal evolution. Longitudinal PDOX models recapitulate the limited genetic evolution of gliomas observed in patient tumors following treatment. PDOX-derived standardized tumor organoid cultures enabled assessment of drug responses, which were validated in mice. PDOXs showed clinically relevant responses to Temozolomide and to targeted treatments such as EGFR and CDK4/6 inhibitors in (epi)genetically defined groups, according to MGMT promoter and EGFR/CDK status respectively. Dianhydrogalactitol, a bifunctional alkylating agent, showed promising potential against glioblastoma. Our study underlines the clinical relevance of glioma PDOX models for translational research and personalized treatment studies. [less ▲]

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See detailPagalbinis vadovas mokytojams
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Vykdant BMC-EU projektą (Pagrindinės motorinės kompetencijos Europoje), buvo sukurta naudojimosi pagalbos ir pagalbos priemonių rinkinys, pagrįstas pagrindinių motorinių kompetencijų koncepcija ir duomenų ... [more ▼]

Vykdant BMC-EU projektą (Pagrindinės motorinės kompetencijos Europoje), buvo sukurta naudojimosi pagalbos ir pagalbos priemonių rinkinys, pagrįstas pagrindinių motorinių kompetencijų koncepcija ir duomenų rinkimo rezultatais pirmame projekto etape, ir kuris yra dalis trečio intelektinio produkto. Šiuo priemonių rinkiniu siekiama paskatinti jį įgyvendinti, ypatingai per reguliarias fizinio ugdymo pamokas, adaptuojant prie fizinio ugdymo mokymo turinio ir metodų. Pirmame etape buvo sukurta pagalbos sistema, skirta mokinių pagrindinių motorinių kompetencijų įvertinimui ir siekiant įvertinimo metu nustatyti stipriosioms ir silpnosioms pusėms. Remiantis šia sistema, buvo sukurti pagalbos priemonių rinkiniai, paruošti diegti konkrečiose ugdymo situacijose, kad būtų naudingi mokiniams, kuriems reikia pagalbos vystant pagrindinius motorinius įgūdžius. Pagalbos priemonių rinkinį sudaro MOBAK (pagrindinės motorinės kompetencijos) testų rezultatų aiškinimo gairės, MOBAK paramos sistema, žodynėlis, taip pat pagalbos priemonių rinkinys, apimantis priemones fizinio ugdymo mokytojams, MOBAK užduočių aprašymo kortelės ir MOBAK veiklų kortelės su fizinių veiklų variacijomis, remiantis į kompetenciją orientuotu požiūriu. [less ▲]

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See detailBoîte à outil pour l'enseignant - Support théorique
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Un cadre théorique de soutien et une boite à outil pédagogique ont été développés dans le cadre du projet BMC-EU (Compétences motrices de base en Europe). Ces documents ont été conçus en tenant compte du ... [more ▼]

Un cadre théorique de soutien et une boite à outil pédagogique ont été développés dans le cadre du projet BMC-EU (Compétences motrices de base en Europe). Ces documents ont été conçus en tenant compte du concept des compétences motrices de base ainsi que des données collectées dans la phase expérimentale (phase 1) du projet. Ils correspondent à l’étape de production intellectuelle n°3. Le cette boîte à outils s’applique principalement dans le cadre des cours d’éducation physique et offre une approche pédagogique permettant d’initier des adaptations de méthode et de contenu pertinentes dans le contexte d’enseignement de l’éducation physique à l’école primaire. Dans la première partie du document, il est expliqué comment passer du diagnostic des compétences motrices de base des élèves, de l’identification de leurs forces et faiblesses à une intervention concrètes et adaptée. Des supports documentaires sous la forme d'une boîte à outils de soutien pédagogique ont été développés dans le respect du cadre théorique de base. Ces supports ont été développés afin d’être facilement être mis en œuvre dans des situations éducatives concrètes visant à soutenir les élèves présentant des faiblesses au niveau de certaines compétences motrices de base. La boîte à outils pour l’enseignant comprend des directives pour l'interprétation des résultats des tests MOBAK (Motorische Basiskompetenzen; traduction allemande pour les compétences motrices de base), le cadre théorique MOBAK, un glossaire, ainsi que la boîte à outils de soutien pédagogique avec du matériel pour les enseignants d'éducation physique sous la forme de fiches décrivant les tests MOBAK et de fiches d'activités MOBAK basées sur des principes de variation des composantes de coordination et sur une approche axée sur le développement des compétences. [less ▲]

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See detailManuale modulare per gli insegnanti
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Nell’ambito del progetto BMC-EU (Competenze motorie di base in Europa), è stato sviluppato un manuale modulare e un allegato riguardante le competenze motorie di base e ai risultati della raccolta dei ... [more ▼]

Nell’ambito del progetto BMC-EU (Competenze motorie di base in Europa), è stato sviluppato un manuale modulare e un allegato riguardante le competenze motorie di base e ai risultati della raccolta dei dati nella fase 1 del progetto come parte dell’analisi dei risultati nella fase 3. Lo scopo di questo allegato è quello di fungere da strumento per implementare principalmente le lezioni di educazione fisica curriculari, consentendo gli adattamenti dei contenuti e dei metodi in educazione fisica. In una prima fase, è stato sviluppato il framework per ottenere la diagnosi delle competenze motorie di base degli allievi e conoscere i punti di forza e di debolezza identificati nella valutazione attraverso interventi concreti. A tal proposito, sono stati realizzati dei documenti sotto forma di un kit e di un manuale, pronti per essere utilizzati in situazioni didattiche concrete, per sostenere gli allievi con bisogni educativi speciali nelle competenze motorie di base. Il manuale modulare include le linee guida per l'interpretazione dei risultati delle prove MOBAK (Motorische Basiskompetenzen; termine tedesco per le competenze motorie di base), il manuale modulare del MOBAK, un glossario, nonché l’allegato con i materiali per gli insegnanti di educazione fisica sotto forma di scheda descrittiva del MOBAK e schede delle attività basate sui principi di variazione del compito motorio e sull’approccio didattico orientato alla competenza. [less ▲]

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See detailPodporný metodický materiál pre učiteľov
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

V rámci projektu BMC-EU (Základné pohybové kompetencie v Európe) bol v prvej fáze projektu na základe koncepcie základných pohybových kompetencií a výsledkov zberu údajov vypracovaný podporný rámec a ... [more ▼]

V rámci projektu BMC-EU (Základné pohybové kompetencie v Európe) bol v prvej fáze projektu na základe koncepcie základných pohybových kompetencií a výsledkov zberu údajov vypracovaný podporný rámec a modulárny podporný súbor nástrojov ako súčasť intelektuálneho výstupu 3. Cieľom tohto súboru nástrojov je implementovať najmä na úrovni pravidelných hodín telesnej výchovy úpravy týkajúce sa obsahu a metód výučby telesnej výchovy. V prvom kroku sa vyvinul podporný rámec na získanie diagnostiky základných pohybových kompetencií detí a žiakov a silných a slabých stránok identifikovaných pri hodnotení až po konkrétne zásahy. Na základe tohto rámca boli vyvinuté podporné materiály vo forme modulárnej podpornej súpravy nástrojov, pripravené na implementáciu v konkrétnych vzdelávacích situáciách na podporu študentov s ďalšími potrebami v základných pohybových kompetenciách. Modulárna podporná sada nástrojov obsahuje pokyny na interpretáciu výsledkov testov MOBAK (Motorische Basiskompetenzen; nemčina pre základné motorické kompetencie), podporný rámec MOBAK, glosár, ako aj modulárnu podpornú sadu nástrojov s materiálmi pre učiteľov telesnej výchovy vo forme MOBAK, karty opisu úloh a karty aktivít MOBAK založené na princípoch variácie a na prístupe orientovanom na kompetencie. [less ▲]

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See detailCoronavirus and the Whistleblower: The (Missing) Role of International Law
Kafteranis, Dimitrios UL

E-print/Working paper (2020)

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See detailMining the NIST Mass Spectral Library Reveals the Extent of Sodium Assisted Inductive Cleavage in Collision-Induced Fragmentation
Ludwig, Marcus; Broeckling, Corey D.; Dorrestein, Pieter et al

E-print/Working paper (2020)

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See detailModulares Support-Toolkit für Lehrkräfte
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Im Rahmen des BMC-EU-Projekts (Motorische Basiskompetenzen in Europa) wurden ein Unterstützungsrahmen und ein modulares Unterstützungs-Toolkit auf der Grundlage des Konzepts der grundlegenden motorischen ... [more ▼]

Im Rahmen des BMC-EU-Projekts (Motorische Basiskompetenzen in Europa) wurden ein Unterstützungsrahmen und ein modulares Unterstützungs-Toolkit auf der Grundlage des Konzepts der grundlegenden motorischen Kompetenzen und der Ergebnisse der Datenerfassung in Phase 1 des Projekts als Teil des intellektuellen Outputs 3entwickelt. Ziel dieses Toolkits ist es, hauptsächlich auf der Ebene des regulären Sportunterrichts umgesetzt zu werden, um Anpassungen hinsichtlich der Inhalte und Methoden des Sportunterrichts einzuleiten. In einem ersten Schritt wurde der Unterstützungsrahmen entwickelt, um von der Diagnose der grundlegenden motorischen Kompetenzen der Schülerinnen und Schüler1 und der in der Bewertung identifizierten Stärken und Schwächen zu konkreten Interventionen zu gelangen. Basierend auf diesem Rahmen wurden unterstützende Handouts in Form eines modularen Support-Toolkits entwickelt, die in konkreten Bildungssituationen implementiert werden können, um Schüler mit zusätzlichen Anforderungen an motorische Basiskompetenzen zu unterstützen. Das modulare Support-Toolkit enthält Richtlinien für die Interpretation der Testergebnisse von MOBAK (Motorische Basiskompetenzen), das MOBAK-Unterstützungsrahmen, ein Glossar sowie das modulare Support-Toolkit mit Materialien für Sportlehrer in Form von MOBAK Aufgabenbeschreibungskarten und MOBAK-Aktivitätskarten basierend auf Variationsprinzipien und einem kompetenzorientierten Ansatz. [less ▲]

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See detailΥποστηρικτική εργαλειοθήκη για εκπαιδευτικούς
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

Στο πλαίσιο του έργου BMC-EU (Βασικές Κινητικές Δεξιότητες στην Ευρώπη) αναπτύχθηκε το πλαίσιο υποστήριξης και η υποστηρικτική εργαλειοθήκη βάση του μοντέλου των βασικών κινητικών δεξιοτήτων και των ... [more ▼]

Στο πλαίσιο του έργου BMC-EU (Βασικές Κινητικές Δεξιότητες στην Ευρώπη) αναπτύχθηκε το πλαίσιο υποστήριξης και η υποστηρικτική εργαλειοθήκη βάση του μοντέλου των βασικών κινητικών δεξιοτήτων και των αποτελεσμάτων από τη συλλογή δεδομένων κατά τη φάση 1 του έργου, το οποίο αποτελεί μέρος της πνευματικής παραγωγής 3. Ο σκοπός της εργαλειοθήκης αυτής είναι να εφαρμοστεί στα μαθήματα φυσικής αγωγής, ώστε να προσαρμοστούν κατάλληλα τόσο το περιεχόμενο όσο και οι μέθοδοι διδασκαλίας της φυσικής αγωγής. Ως πρώτο βήμα, το υποστηρικτικό πλαίσιο αναπτύχθηκε για τη διάγνωση των βασικών κινητικών δεξιοτήτων των μαθητών, καθώς και για την αξιολόγηση των δυνατοτήτων τους, ώστε στη συνέχεια να δημιουργηθούν συγκεκριμένα παρεμβατικά προγράμματα. Με βάση το πλαίσιο αυτό, αναπτύχθηκαν υποστηρικτικά φυλλάδια με τη μορφή της υποστηρικτικής εργαλειοθήκης, έτοιμα προς εφαρμογή σε συγκεκριμένες εκπαιδευτικές συνθήκες για την υποστήριξη μαθητών με πρόσθετες ανάγκες στις βασικές κινητικές δεξιότητες. Η υποστηρικτική εργαλειοθήκη περιλαμβάνει οδηγίες για την ερμηνεία των αποτελεσμάτων του MOBAK (Motorische Basiskompetenzen; Γερμανικά για τις βασικές κινητικές δεξιότητες), το πλαίσιο υποστήριξης ΜΟΒΑΚ, ένα γλωσσάρι, καθώς και την υποστηρικτική εργαλειοθήκη με εργαλεία για καθηγητές φυσικής αγωγής υπό τη μορφή καρτών περιγραφής διαδικασιών και καρτών δραστηριοτήτων ΜΟΒΑΚ, βασισμένα στις αρχές της παραλλαγής των δραστηριοτήτων και σε μία προσέγγιση προσανατολισμένη στις δεξιότητες. [less ▲]

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See detailOn Reductions of Hintikka Sets for Higher-Order Logic
Steen, Alexander UL; Benzmüller, Christoph UL

E-print/Working paper (2020)

Detailed reference viewed: 72 (2 UL)
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See detailModular Support Toolkit for Teachers
Scheuer, Claude UL; Heck, Sandra UL

E-print/Working paper (2020)

In the frame of the BMC-EU project (Basic motor competencies in Europe), a support framework and a modular support toolkit on the basis of the concept of basic motor competences and the results of the ... [more ▼]

In the frame of the BMC-EU project (Basic motor competencies in Europe), a support framework and a modular support toolkit on the basis of the concept of basic motor competences and the results of the data collection in phase 1 of the project was developed as part of intellectual output 3. The aim of this toolkit is to be implemented mainly at the level of regular physical education lessons to initiate adaptations regarding the content and methods in physical education instruction. In a first step, the support framework was developed for getting from the diagnosis of the students’ basic motor competencies and the strengths and weaknesses identified in the assessment to concrete interventions. Based on this framework, supportive handouts in form of a modular support toolkit were developed, ready to be implemented in concrete educational situations to support students with additional needs in basic motor competencies. The modular support toolkit includes guidelines for the interpretation of MOBAK (Motorische Basiskompetenzen; German for basic motor competencies) test results, the MOBAK support framework, a glossary, as well as the modular support toolkit with materials for physical education teachers in the form of MOBAK task description cards and MOBAK activity cards based on principles of variation and on a competence-oriented approach. [less ▲]

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See detailBitcoin Governance as a Decentralized Financial Market Infrastructure
Nabilou, Hossein UL

E-print/Working paper (2020)

Bitcoin is the oldest and most widely established cryptocurrency network with the highest market capitalization among all cryptocurrencies. Although bitcoin (with lowercase b) is increasingly viewed as a ... [more ▼]

Bitcoin is the oldest and most widely established cryptocurrency network with the highest market capitalization among all cryptocurrencies. Although bitcoin (with lowercase b) is increasingly viewed as a digital asset belonging to a new asset class, the Bitcoin network (with uppercase B) is a decentralized financial market infrastructure (dFMI) that clears and settles transactions in its native asset without relying on the conventional financial market infrastructures (FMIs). To be a reliable asset class as well as a dFMI, however, Bitcoin needs to have robust governance arrangements; whether such arrangements are built into the protocol (i.e., on-chain governance mechanisms) or relegated to the participants in the Bitcoin network (i.e., off-chain governance mechanisms), or are composed of a combination of both mechanisms (i.e., a hybrid form of governance). This paper studies Bitcoin governance with a focus on its alleged shortcomings. In so doing, after defining Bitcoin governance and its objectives, the paper puts forward an idiosyncratic governance model whose main objective is to preserve and maximize the main value proposition of Bitcoin, i.e., its censorship-resistant property, which allows participants to transact in an environment with minimum social trust. Therefore, Bitcoin governance, including the processes through which Bitcoin governance crises have been resolved and the standards against which the Bitcoin Improvement Proposals (BIPs) are examined, should be analyzed in light of the prevailing narrative of Bitcoin as a censorship-resistant store of value and payment infrastructure. Within such a special governance model, this paper seeks to identify the potential shortcomings in Bitcoin governance by reference to the major governance crises that posed serious threats to Bitcoin in the last decade. It concludes that the existing governance arrangements in the Bitcoin network have been largely successful in dealing with Bitcoin’s major crises that would have otherwise become existential threats to the Bitcoin network. [less ▲]

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See detailCustomary Land Conversion and the Formation of the African City
Picard, Pierre M UL; Selod, Harris

E-print/Working paper (2020)

As cities grow and spatially expand, agricultural land is converted into residential land. In many developing countries, especially in Sub-Saharan Africa, this process is accompanied by a change in land ... [more ▼]

As cities grow and spatially expand, agricultural land is converted into residential land. In many developing countries, especially in Sub-Saharan Africa, this process is accompanied by a change in land tenure, whereby plots held under traditional customary arrangements are sold to new urban residents, possibly with formal property rights. This paper studies joint land-use and land-tenure conversion in an urban economics model in which intermediaries purchase agricultural land from customary owners and attempt to transform it into residential plots with statutory property rights. The spatial equilibrium includes a mix of land uses and rights where statutory and non-statutory residential plots coexist with customary land that is mainly used for agriculture. Because customary ownership is subject to uncertainty (because of tenure insecurity), the conversion process includes a potential information asymmetry between customary owners and intermediaries. The analysis shows that a market failure may emerge whereby some customary owners prefer to continue farming their land rather than participate in the urban residential land market, which results in a city that is too small. Empirical analysis using Malian data validates the key features of the model captured by land price gradients, as well as the ranking and the variance of land prices, and is suggestive of the presence of information asymmetry. [less ▲]

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See detailBeing a World Young Leader in Dementia: Between academic brilliance and acts of kindness. Blog post
Leist, Anja UL

E-print/Working paper (2020)

The blog post describes my journey from being selected as an 'Emerging Leader in Dementia' in 2014/15 by the UK Science and Innovation Network to helping to form, with other emerging leaders, a truly ... [more ▼]

The blog post describes my journey from being selected as an 'Emerging Leader in Dementia' in 2014/15 by the UK Science and Innovation Network to helping to form, with other emerging leaders, a truly global network of World Young Leaders in Dementia, now spanning 400+ members in 29+ countries, and aiming to facilitate careers of young professionals in the field of dementia. [less ▲]

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See detailMeasuring Pants
Doan, Nhat Minh UL; Parlier, Hugo UL; Tan, Ser Peow

E-print/Working paper (2020)

We investigate the terms arising in an identity for hyperbolic surfaces proved by Luo and Tan, namely showing that they vary monotonically in terms of lengths and that they verify certain convexity ... [more ▼]

We investigate the terms arising in an identity for hyperbolic surfaces proved by Luo and Tan, namely showing that they vary monotonically in terms of lengths and that they verify certain convexity properties. Using these properties, we deduce two results. As a first application, we show how to deduce a theorem of Thurston which states, in particular for closed hyperbolic surfaces, that if a simple length spectrum "dominates" another, then in fact the two surfaces are isometric. As a second application, we show how to find upper bounds on the number of pairs of pants of bounded length that only depend on the boundary length and the topology of the surface. [less ▲]

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See detailChancen der Jugendarbeit und non-formaler Bildung an Schulen
Biewers, Sandra UL

E-print/Working paper (2020)

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See detailDepressionen am Arbeitsplatz in Luxemburg: ein Handlungsfeld
Sischka, Philipp UL; Steffgen, Georges UL

E-print/Working paper (2020)

Im Rahmen dieser Newsletter wird das aktuelle Depressionsrisiko am Arbeitsplatz in Luxemburg vorgestellt. Im Vergleich zu anderen europäischen Ländern weist Luxemburg einen relativ hohen Anteil an ... [more ▼]

Im Rahmen dieser Newsletter wird das aktuelle Depressionsrisiko am Arbeitsplatz in Luxemburg vorgestellt. Im Vergleich zu anderen europäischen Ländern weist Luxemburg einen relativ hohen Anteil an Arbeitnehmern mit Depressionsrisiko. Weibliche Arbeitnehmer sind im Vergleich zu männlichen geringfügig häufiger von einem Depressionsrisiko betroffen. Differenziert nach Beruf sind vor allem Hilfsarbeitskräfte, Manager sowie Arbeitnehmer in Dienstleistungsberufen besonders von einem Depressionsrisiko betroffen. Arbeitnehmer mit Depressionsrisiko berichten über nachteilige Arbeitsbedingungen und weisen auch eine geringere Arbeitsplatzzufriedenheit sowie weitere gesundheitliche Probleme auf. [less ▲]

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See detailExponential contraction in Wasserstein distance on static and evolving manifolds
Cheng, Li Juan UL; Thalmaier, Anton UL; Zhang, Shao-Qin

E-print/Working paper (2020)

In this article, exponential contraction in Wasserstein distance for heat semigroups of diffusion processes on Riemannian manifolds is established under curvature conditions where Ricci curvature is not ... [more ▼]

In this article, exponential contraction in Wasserstein distance for heat semigroups of diffusion processes on Riemannian manifolds is established under curvature conditions where Ricci curvature is not necessarily required to be non-negative. Compared to the results of Wang (2016), we focus on explicit estimates for the exponential contraction rate. Moreover, we show that our results extend to manifolds evolving under a geometric flow. As application, for the time-inhomogeneous semigroups, we obtain a gradient estimate with an exponential contraction rate under weak curvature conditions, as well as uniqueness of the corresponding evolution system of measures. [less ▲]

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See detailFluctuations for matrix-valued Gaussian processes
Jaramillo Gil, Arturo UL; Pardo Millan, Juan Carlos; Diaz Torres, Mario Alberto

E-print/Working paper (2020)

We consider a symmetric matrix-valued Gaussian process $Y^{(n)}=(Y^{(n)}(t);t\ge0)$ and its empirical spectral measure process $\mu^{(n)}=(\mu_{t}^{(n)};t\ge0)$. Under some mild conditions on the ... [more ▼]

We consider a symmetric matrix-valued Gaussian process $Y^{(n)}=(Y^{(n)}(t);t\ge0)$ and its empirical spectral measure process $\mu^{(n)}=(\mu_{t}^{(n)};t\ge0)$. Under some mild conditions on the covariance function of $Y^{(n)}$, we find an explicit expression for the limit distribution of $$Z_F^{(n)} := \left( \big(Z_{f_1}^{(n)}(t),\ldots,Z_{f_r}^{(n)}(t)\big) ; t\ge0\right),$$ where $F=(f_1,\dots, f_r)$, for $r\ge 1$, with each component belonging to a large class of test functions, and $$ Z_{f}^{(n)}(t) := n\int_{\R}f(x)\mu_{t}^{(n)}(\ud x)-n\E\left[\int_{\R}f(x)\mu_{t}^{(n)}(\ud x)\right].$$ More precisely, we establish the stable convergence of $Z_F^{(n)}$ and determine its limiting distribution. An upper bound for the total variation distance of the law of $Z_{f}^{(n)}(t)$ to its limiting distribution, for a test function $f$ and $t\geq0$ fixed, is also given. [less ▲]

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See detailA newform theory for Katz modular forms
Berhanu, Daniel UL

E-print/Working paper (2020)

In this paper, a strong multiplicity one theorem for Katz modular forms is studied. We show that a cuspidal Katz eigenform which admits an irreducible Galois representation is in the level and weight old ... [more ▼]

In this paper, a strong multiplicity one theorem for Katz modular forms is studied. We show that a cuspidal Katz eigenform which admits an irreducible Galois representation is in the level and weight old space of a uniquely associated Katz newform. We also set up multiplicity one results for Katz eigenforms which have reducible Galois representation. [less ▲]

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See detailpatRoon: Open Source Software Platform for Environmental Mass Spectrometry Based Non-target Screening
Helmus, Rick; ter Laak, Thomas; van Wezel, Annemarie et al

E-print/Working paper (2020)

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See detailIn-work poverty in times of pandemic
Ratti, Luca UL

E-print/Working paper (2020)

The coronavirus crisis is exacerbating in-work poverty in the EU—and a powerful raft of labour-market and welfare measures is needed for an adequate response.

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See detailDecentralized Finance (DeFi)
Zetzsche, Dirk Andreas UL; Buckley, Ross; Arner, Douglas

E-print/Working paper (2020)

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Peer Reviewed
See detailPoverty in Russia: the Role of the Marital Status and Gender
Zanaj, Skerdilajda UL

E-print/Working paper (2020)

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See detailAfter Libra, Digital Yuan and COVID-19: Central Bank Digital Currencies and the New World of Money and Payment Systems
Zetzsche, Dirk Andreas UL; Arner, Douglas; Buckley, Ross et al

E-print/Working paper (2020)

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See detailAssessing suppression strategies against epidemicoutbreaks like COVID-19: the SPQEIR model
Proverbio, Daniele UL; Kemp, Francoise UL; Magni, Stefano UL et al

E-print/Working paper (2020)

The current COVID-19 outbreak represents a most serious challenge for societies worldwide. It isendangering the health of millions of people, and resulting in severe socioeconomic challenges dueto lock ... [more ▼]

The current COVID-19 outbreak represents a most serious challenge for societies worldwide. It isendangering the health of millions of people, and resulting in severe socioeconomic challenges dueto lock-down measures. Governments worldwide aim to devise exit strategies to revive the economywhile keeping the pandemic under control. The problem is that the effects of distinct measures arenot well quantified. This paper compares several suppression approaches and potential exit strategiesusing a new extended epidemic SEIR model. It concludes that while rapid and strong lock-down isan effective pandemic suppression measure, a combination of other strategies such as social distanc-ing, active protection and removal can achieve similar suppression synergistically. This quantitativeunderstanding will support the establishment of mid- and long-term interventions. Finally, the paperprovides an online tool that allows researchers and decision makers to interactively simulate diversescenarios with our model. [less ▲]

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See detailCorporate Technologies
Zetzsche, Dirk Andreas UL; Enriques, Luca

E-print/Working paper (2020)

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See detailFintech Toolkit: Smart Regulatory and Market Approaches to Financial Technology Innovation
Zetzsche, Dirk Andreas UL; Arner, Douglas; Buckley, Ross et al

E-print/Working paper (2020)

Detailed reference viewed: 48 (0 UL)
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See detailArtificial Intelligence in Finance: Putting the Humans in the Loop
Zetzsche, Dirk Andreas UL; Tang, Brian; Buckley, Ross et al

E-print/Working paper (2020)

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See detailDigital Finance & The COVID-19 Crisis
Zetzsche, Dirk Andreas UL; Arner, Douglas; Barberis, Janos Nathan et al

E-print/Working paper (2020)

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Peer Reviewed
See detailJust because they say it is sustainable development, it does not mean that it is: Sustainable development as a master-signifier in Swiss urban and regional planning
Carr, Constance UL

E-print/Working paper (2020)

With stunning green landscapes, exemplary public transport, and picturesque walkable cities, Switzerland often occupies the public imaginary of a place that has tackled sustainable development. This ... [more ▼]

With stunning green landscapes, exemplary public transport, and picturesque walkable cities, Switzerland often occupies the public imaginary of a place that has tackled sustainable development. This research, however, looks under the hood and finds that this development path supports not only modes of capital accumulation, but also certain less sustainable patterns of development and governance. This paper examines this apparent paradox by looking at the role of sustainable development as a master-signifier in Swiss urban development processes. Empirical observations were made in the Glatt Valley of Switzerland, where governing officials of small municipalities are confronted with coordinating urban development under growth pressure within cantonal and federal policy frameworks that claim sustainable development. It can be seen that sustainable development is an empty master-signifier that policy makers engage to justify the quilting of a certain hegemonic discourses of power that reflect in further uneven urban development. By reproducing business as usual market-led urban growth, fragmentation is maintained as are social spatial disparities are entrenched. [less ▲]

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See detailOn the distribution of the order and index for the reductions of algebraic numbers
Sgobba, Pietro UL

E-print/Working paper (2020)

Let \alpha_1,...,\alpha_r be algebraic numbers in a number field K generating a subgroup of rank r in K*. We investigate under GRH the number of primes p of K such that each of the orders of (\alpha_i mod ... [more ▼]

Let \alpha_1,...,\alpha_r be algebraic numbers in a number field K generating a subgroup of rank r in K*. We investigate under GRH the number of primes p of K such that each of the orders of (\alpha_i mod p) lies in a given arithmetic progression associated to (\alpha_i). We also study the primes p for which the index of (\alpha_i mod p) is a fixed integer or lies in a given set of integers for each i. An additional condition on the Frobenius conjugacy class of p may be considered. Such results are generalizations of a theorem of Ziegler from 2006, which concerns the case r=1 of this problem. [less ▲]

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See detailGeographical Stratification of Green Urban Areas
Picard, Pierre M UL; Tran, Thi Thu Huyen UL

E-print/Working paper (2020)

This paper studies the provision of urban green areas in cities when residents havepreferences for the size of and access to those areas. At the optimum, the number ofurban green spaces is a non-monotone ... [more ▼]

This paper studies the provision of urban green areas in cities when residents havepreferences for the size of and access to those areas. At the optimum, the number ofurban green spaces is a non-monotone function of distance to the city centre, whilethe sizes and distances to other urban green areas increase as one moves to the urbanfringe. This paper empirically investigates those properties for the 300 largest Europeancities by using the GMES Urban Atlas database (European Environmental Agency).The empirical analysis confirms the non-monotone relationship between the numberof urban green spaces and the distance to the city centre. The distance between twoparks also increases as one moves toward the urban fringe. Finally, richer cities areassociated with a denser network of urban green areas. [less ▲]

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See detailChallenging the Olympic Charter at the Swiss OECD National Contact Point
Baglayan, Basak UL

E-print/Working paper (2020)

Detailed reference viewed: 117 (0 UL)
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See detailNormal approximation for functions of hidden Markov models
Kerchev, George UL

E-print/Working paper (2020)

Detailed reference viewed: 35 (2 UL)
See detailCausal dynamical modelling predicts novel regulatory genes of FOXP3 in human regulatory T cells
Sawlekar, Rucha UL; Magni, Stefano UL; Chapelle, Christophe et al

E-print/Working paper (2020)

Detailed reference viewed: 58 (5 UL)
See detailCultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips
Spitz, Sarah; Zanetti, Cristian; Bolognin, Silvia UL et al

E-print/Working paper (2019)

Detailed reference viewed: 31 (2 UL)
See detailFrom deformation theory of wheeled props to classification of Kontsevich formality maps
Andersson, Assar UL; Merkulov, Sergei UL

E-print/Working paper (2019)

We study homotopy theory of the wheeled prop controlling Poisson structures on arbitrary formal graded finite-dimensional manifolds and prove, in particular, that Grothendieck-Teichmueller group acts on ... [more ▼]

We study homotopy theory of the wheeled prop controlling Poisson structures on arbitrary formal graded finite-dimensional manifolds and prove, in particular, that Grothendieck-Teichmueller group acts on that wheeled prop faithfully and homotopy non-trivially. Next we apply this homotopy theory to the study of the deformation complex of an arbitrary Maxim Kontsevich formality map and compute the full cohomology group of that deformation complex in terms of the cohomology of a certain graph complex introduced earlier by Maxim Kontsevich in [K1] and studied by Thomas Willwacher in [W1]. [less ▲]

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See detailA Directive to protect whistle-blowers
Kafteranis, Dimitrios UL

E-print/Working paper (2019)

Detailed reference viewed: 28 (2 UL)
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Peer Reviewed
See detailParliamentary Administrations in EU Politics: The Sources and Impact of Diversity
Högenauer, Anna-Lena UL

E-print/Working paper (2019)

National parliaments tend to delegate a range of tasks related to EU affairs scrutiny to their administrations. However, there is considerable variation in the extent to which national parliaments invest ... [more ▼]

National parliaments tend to delegate a range of tasks related to EU affairs scrutiny to their administrations. However, there is considerable variation in the extent to which national parliaments invest in EU affairs staff. This raises two questions: what is the source of this diversity, and what is its impact on the EU affairs scrutiny of national parliaments? This paper argues that greater investments in EU affairs staff are associated with public Euroscepticism, large parliaments and parliaments with strong scrutiny powers. A large EU staff is, in turn, associated with parliaments that are relatively active in EU affairs scrutiny. This is particularly true for the 15 EU member states that joined before 2004. [less ▲]

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See detailL'espace sportif européen: circulations, organisations et identité européenne
Moreau, Sebastien UL; Sbetti, Nicola; Dufraisse, Sylvain et al

E-print/Working paper (2019)

Dès la fin du xixe siècle, l’espace européen est le cadre d’un développement précoce des échanges sportifs et tient un rôle pionnier dans l’organisation internationale des sports. L’homogénéisation des ... [more ▼]

Dès la fin du xixe siècle, l’espace européen est le cadre d’un développement précoce des échanges sportifs et tient un rôle pionnier dans l’organisation internationale des sports. L’homogénéisation des pratiques et la mise en place de compétitions continentales, processus commencé dans l’entre-deux-guerres et qui se renforce après la Deuxième Guerre mondiale, a comme effet la constitution d’un espace sportif européen. Touchant autant les élites que les masses et le produit d’une intense médiatisation, les sports ont un impact qui dépasse largement les stades et permettent aux Européens de se rencontrer et in fine de mieux se connaître. [less ▲]

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See detailTransport properties of Majorana bound states networks in the Coulomb blockade regime
Ekström, Carl Johan Ingvar UL; Recher, Patrik; Schmidt, Thomas UL

E-print/Working paper (2019)

Topologically protected qubits based on nanostructures hosting Majorana bound states (MBSs) hold great promise for fault-tolerant quantum computing. We study the transport properties of nanowire networks ... [more ▼]

Topologically protected qubits based on nanostructures hosting Majorana bound states (MBSs) hold great promise for fault-tolerant quantum computing. We study the transport properties of nanowire networks hosting MBSs with a focus on the effects of the charging energy and the overlap between neighboring MBSs in short mesoscopic samples. In particular, we investigate structures hosting four MBSs such as T-junctions and Majorana boxes. Using a master equation in the Markovian approximation, we discuss the leading transport processes mediated by the MBSs. Single-electron tunneling and processes involving creation and annihilation of Cooper pairs dominate in the sequential tunneling limit. In the cotunneling regime the charge in the MBSs network is fixed and transport is governed by transitions via virtual intermediate states. Our results show that four-terminal measurements in the T-junction and Majorana box geometries can be useful tools for the characterization of the properties of MBSs with finite overlaps and charging energy. [less ▲]

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See detailThe 2019 European Parliament Elections in Luxembourg in the Context of Past Elections
Högenauer, Anna-Lena UL

E-print/Working paper (2019)

The aim of this article is to analyse the 2019 European election in Luxembourg and to contextualize it by comparing it with past elections. The article presents the party landscape, the electoral campaign ... [more ▼]

The aim of this article is to analyse the 2019 European election in Luxembourg and to contextualize it by comparing it with past elections. The article presents the party landscape, the electoral campaign, the electoral system and the results of the 2019 European election. The results are then analysed in the context of past national and European elections in order to establish whether European elections are second-order elections in Luxembourg, how electoral volatility evolved over time, whether there is a rise in Eurosceptic parties and how the representation of women has evolved since 1979. [less ▲]

Detailed reference viewed: 42 (1 UL)