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See detailFigures de l'intime et de l'extime : réflexions à partir du jeu de Marina Hands et d'Éric Ruf face à Phèdre de Jean Racine et à Partage de midi de Paul Claudel
Deregnoncourt, Marine UL

Doctoral thesis (2023)

Entitled “The Figures of intimacy and extimacy: a Reflection on Marina Hands and Eric Ruf’s acting in Jean Racine's Phèdre and Paul Claudel's Partage de midi”, this PhD dissertation addresses the concepts ... [more ▼]

Entitled “The Figures of intimacy and extimacy: a Reflection on Marina Hands and Eric Ruf’s acting in Jean Racine's Phèdre and Paul Claudel's Partage de midi”, this PhD dissertation addresses the concepts of “intimacy” and “extimacy” as witnessed through Marina Hands and Eric Ruf’s vocal and scenic acting in Patrice Chereau and Yves Beaunesne’s respective productions of Racine's and Claudel's works. In the frame of these two shows both actors manage to suggest “extimacy” with their body language, and to render “intimacy” thanks to their “singing” diction of Racine’s alexandrine and Claudel’s free verse. Throughout our development, we will display perpetual links between Racine and Claudel, as suggested by the singular acting of these two performers. The problematic axis of this dissertation is thus the following: “how does the combination of the “extimacy” of Marina Hands and Éric Ruf’s body-language and the “intimacy” of their “singing” diction reveal the musicality of Racine’s and Claudel’s languages?”. We shall see that “intimacy” turns out to be “extimacy” on stage, and that the two concepts are nothing but two sides of the same coin. “Intimacy” is the constant object of both Patrice Chereau's and Yves Beaunesne's research, to the extent that it constitutes the essence of their artistic creations. In order to become “extimacy”, “intimacy” has to be mediated by actors’ bodies if it means to serve the text actually heard on stage. The union between body and text is therefore a central issue. [less ▲]

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See detailPanel Organiser: Veterans' Welfare in European Borderlands through the 20th Century
Venken, Machteld UL

Presentation (2023, February 16)

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See detailInvestigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers
Sugier, Pierre-Emmanuel; Lucotte, Elise A.; Domenighetti, Cloé et al

in Movement Disorders (2023), n/a(n/a),

Abstract Background Epidemiological studies that examined the association between Parkinson's disease (PD) and cancers led to inconsistent results, but they face a number of methodological difficulties ... [more ▼]

Abstract Background Epidemiological studies that examined the association between Parkinson's disease (PD) and cancers led to inconsistent results, but they face a number of methodological difficulties. Objective We used results from genome-wide association studies (GWASs) to study the genetic correlation between PD and different cancers to identify common genetic risk factors. Methods We used individual data for participants of European ancestry from the Courage-PD (Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease; PD, N = 16,519) and EPITHYR (differentiated thyroid cancer, N = 3527) consortia and summary statistics of GWASs from iPDGC (International Parkinson Disease Genomics Consortium; PD, N = 482,730), Melanoma Meta-Analysis Consortium (MMAC), Breast Cancer Association Consortium (breast cancer), the Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome (prostate cancer), International Lung Cancer Consortium (lung cancer), and Ovarian Cancer Association Consortium (ovarian cancer) (N comprised between 36,017 and 228,951 for cancer GWASs). We estimated the genetic correlation between PD and cancers using linkage disequilibrium score regression. We studied the association between PD and polymorphisms associated with cancers, and vice versa, using cross-phenotypes polygenic risk score (PRS) analyses. Results We confirmed a previously reported positive genetic correlation of PD with melanoma (Gcorr = 0.16 [0.04; 0.28]) and reported an additional significant positive correlation of PD with prostate cancer (Gcorr = 0.11 [0.03; 0.19]). There was a significant inverse association between the PRS for ovarian cancer and PD (odds ratio [OR] = 0.89 [0.84; 0.94]). Conversely, the PRS of PD was positively associated with breast cancer (OR = 1.08 [1.06; 1.10]) and inversely associated with ovarian cancer (OR = 0.95 [0.91; 0.99]). The association between PD and ovarian cancer was mostly driven by rs183211 located in an intron of the NSF gene (17q21.31). Conclusions We show evidence in favor of a contribution of pleiotropic genes to the association between PD and specific cancers. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA. [less ▲]

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See detailInvestigation of OpenFOAM-XDEM momentum coupling results for AWJC Nozzle using preCICE
Adhav, Prasad UL; Besseron, Xavier UL; Peters, Bernhard UL

Scientific Conference (2023, February 14)

The high-speed water jet is the momentum source in an Abrasive Water Jet Cutting Nozzle. This momentum is transferred to the abrasive particles & the air within the nozzle. This leads to turbulent ... [more ▼]

The high-speed water jet is the momentum source in an Abrasive Water Jet Cutting Nozzle. This momentum is transferred to the abrasive particles & the air within the nozzle. This leads to turbulent & complex particle-laden flow in the nozzle. These flow conditions can influence particle impacts on the nozzle, thus influencing erosion. Hence it is imperative that this complex particle-laden flow is captured correctly. The momentum exchange can be directly from the water jet to the particles or indirectly through the airflow. In this work, we investigate these fluid-particle momentum exchanges. Our prototype uses preCICE for volumetric coupling of XDEM (for the particle motion), & OpenFOAM (for the fluid). XDEM uses fluid flow conditions to compute the forces acting on particles. XDEM computes the particle momentum source that is injected into the fluid solver. The results of the coupled simulation align with literature & can be extended to include the FEM component for erosion predictions. [less ▲]

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See detailContracts and Human Rights & Environmental Due Diligence (HREDD) Laws
Lichuma, Caroline Omari UL; Dadush, Sarah; Schönfelder, Daniel et al

Conference given outside the academic context (2023)

How are contracts typically used in HREDD? Does contracting-as-usual support effective HREDD -- why / why not? What do the new laws say about contracts and the role they should play in HREDD? Specifically ... [more ▼]

How are contracts typically used in HREDD? Does contracting-as-usual support effective HREDD -- why / why not? What do the new laws say about contracts and the role they should play in HREDD? Specifically, what do the new laws say about contracts and HREDD-related liability? Against this backdrop, what would you advise in-scope companies to include in their contracts to meet the new legal requirements? Article 12 of the EU’s proposed Corporate Sustainability Due Diligence Directive indicates that the European Commission will develop guidance on model contractual clauses that companies can use to inform their own contracting practices. What are some key principles of due diligence-aligned contracting that you would like to see reflected in this guidance? More generally, what improvements are needed for contracts to better support HREDD regimes that effectively prevent and remedy adverse impacts? [less ▲]

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See detailNegotiating the aesthetics of mourning in Luxembourg: on pre-modern forms in post-modern spaces
Boesen, Elisabeth UL

in House, Danielle; Westendorp, Mariske; Maddrell, Avril (Eds.) New Perspectives on Urban Deathscapes Continuity, Change, and Contestation (2023)

Comparative studies on funeral cultures are mainly concerned with differences related to religious diversity. On Luxembourgish cemeteries, religious differences have been, until recently, largely ... [more ▼]

Comparative studies on funeral cultures are mainly concerned with differences related to religious diversity. On Luxembourgish cemeteries, religious differences have been, until recently, largely irrelevant. An explanation for this can be found in the country’s immigration policy that was based on the principle that religious conformity, i.e. adherence to Roman Catholicism, be a condition for immigration. This did not prevent the country’s urban cemeteries from becoming representations of a culturally diverse immigration society. The paper concentrates on the funeral culture of Cape Verdean migrants, which is characterized by collective ritual mourning and puts into question conventional distinctions of public/private and sacred/mundane spaces. By analyzing various aspects of the negotiation of funeral aesthetics – the materiality of the grave, the expressive modes of mourning, and the social encounters involved – the author makes a plea for a more encompassing understanding of the notion of ‘deathscape’ that transcends fundamental dimensions of the modern functional differentiation of space. [less ▲]

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See detailThe Vulnerability of Young Refugees Living in Reception Centres in Luxembourg: An Overview of Conditions and Experiences across Subjective Temporal Imaginaries
Gilodi, Amalia UL; Richard, Catherine UL; Albert, Isabelle UL et al

in Social Sciences (2023), 12(02),

Vulnerability has become a key concept in discourses and policies on international protection and reception of refugees. In this context, the notion has been described as a tool to provide special ... [more ▼]

Vulnerability has become a key concept in discourses and policies on international protection and reception of refugees. In this context, the notion has been described as a tool to provide special provisions to groups at higher risk or one to perpetuate political agendas within increasingly hostile reception systems. However, vulnerability as an analytical concept has received less attention, with both policymakers and scholars often employing different conceptualisations of vulnerability or treating it as a self-explanatory condition. Building on a previous conceptual elaboration, this paper sets out to apply an understanding of vulnerability as multi-layered, dynamic and embedded in a study of the lived experiences of a group of potentially ‘vulnerable’ migrants, based on ‘fixed’ contextual criteria. Drawing from in-depth interviews with young adults who obtained refugee status in Luxembourg but still live in ‘temporary’ reception centres, this paper provides a wide analytical overview of the conditions of vulnerability encountered by this specific group of migrants, in the process of building their lives in a new country. Following the participants’ subjective temporal imaginaries of past, present and future, the analysis highlights and problematises conditions of structural, situational and experiential vulnerability emerging from their accounts and experiences, and discusses their possible implications. [less ▲]

Detailed reference viewed: 85 (13 UL)
See detailYiddish Periodicals in Germany - Dataset V1
Zaagsma, Gerben UL

Textual, factual or bibliographical database (2023)

This repository contains a dataset of known historical Yiddish newspapers and periodicals published in Germany. The list is based upon cataloguing and holding information from the libraries and book ... [more ▼]

This repository contains a dataset of known historical Yiddish newspapers and periodicals published in Germany. The list is based upon cataloguing and holding information from the libraries and book listed below. The list is provided as an Excel sheet and is a work in progress. Currently the list contains 227 items, 21 of which are available in digitised form. URLs for the digitised periodicals are provided; the list also provides holding locations for the other periodicals but no direct links (yet) to their online catalog records. Any comments and additions are most welcome, please get in touch via: gerben.zaagsma@uni.lu. [less ▲]

Detailed reference viewed: 41 (3 UL)
See detailPresenter: Border Temporalities in the Greater Region
Venken, Machteld UL

Presentation (2023, February 14)

Detailed reference viewed: 18 (0 UL)
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See detailPrecision Observations for Geodynamics, Earthquakes and Earth Tides Phenomena: Introduction
Braitenberg, Carla; Sun, Heping; Feng, Wei et al

in Pure and Applied Geophysics (2023)

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See detailStudents’ perspectives on their academic achievement during the Covid-19 pandemic: learner autonomy, school satisfaction and adult support
Kirsch, Claudine UL; Vaiouli, Potheini UL

in Social Sciences and Humanities Open (2023), 7

Distance education, used to contain the spread of Covid-19 in 2020, radically altered adolescents’ learning experiences and affected their academic achievements. Based on a survey with adolescents aged 12 ... [more ▼]

Distance education, used to contain the spread of Covid-19 in 2020, radically altered adolescents’ learning experiences and affected their academic achievements. Based on a survey with adolescents aged 12-16 in Luxembourg, this study investigates the differences the 332 adolescents perceived in schoolwork when learning at school and from home during the pandemic in 2021, as well as predictors of their reported academic achievement. The findings show that the participants perceived their work as less interesting or useful and more difficult while learning from home and that the main predictors of their academic achievements were school achievements before the pandemic, school satisfaction, learner autonomy, and the ways that adults listen to them. Teacher and parent support played a subordinate role. [less ▲]

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See detailFAIR Game
Schymanski, Emma UL

in Analytical Scientist (2023)

Why Open and FAIR data sharing in analytical research is important for public data availability, raising awareness of your data, and the very future of analytical science – according to Emma Schymanski

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See detailChoosing Women in Postwar Elections: Exposure to War Violence, Ideology, and Voters’ Gender Bias
Glaurdic, Josip UL; Lesschaeve, Christophe

in Politics and Gender (2023), First View

The level of women’s parliamentary representation often increases after armed conflict, but do voters in postwar societies actually prefer female electoral candidates? We answer this question by analyzing ... [more ▼]

The level of women’s parliamentary representation often increases after armed conflict, but do voters in postwar societies actually prefer female electoral candidates? We answer this question by analyzing a unique data set containing information on nearly 7,000 candidates running in three elections with preferential voting in postwar Croatia. Our analysis demonstrates that voters’ gender bias is conditional on the local electorate’s ideology and exposure to war violence, with voters of right-wing parties and voters in areas more affected by war violence being more biased against female candidates. These effects of ideology and exposure to war violence also exhibit a strong interactive relationship, suggesting that bias against women is strongest among right-wing voters in areas exposed to war violence and reversed among left-wing voters in areas exposed to war violence. Our findings highlight the need to better understand the relationship between gender, ideology, and violence in postconflict societies. [less ▲]

Detailed reference viewed: 31 (2 UL)
See detailEstimating terrestrial water storage variations from GNSS vertical displacements in the Island of Haiti
Sauveur, Renaldo UL

Doctoral thesis (2023)

In the field of hydro-geodesy, ill-posed inverse problems are very common. Those problems need to be regularized to find a stabilized solution. Usually, to solve those problems, two regularization methods ... [more ▼]

In the field of hydro-geodesy, ill-posed inverse problems are very common. Those problems need to be regularized to find a stabilized solution. Usually, to solve those problems, two regularization methods are often used, Tikhonov’s regularization and Truncated Singular Value Decomposition (TSVD), with some common regularization parameter choice methods such as L-curve or General Cross Validation (GCV). This study aims to test the capacity of the Least Squares Collocation (LSC) method to estimate the terrestrial water storage variations as an original approach. First, for the forward model, we calculated the hydrological crustal loading deformation in the island of Haiti by convolving Farrell (1972) Green's function with the surface mass loading from the Global Land Data Assimilation (GLDAS). After, a dense synthetic Global Navigation Satellite System (GNSS) network is used with the LSC method to estimate the Terrestrial Water Storage (TWS) variations for the inverse problem. LSC is a natural way to stabilize an ill-posed inverse problem. Unlike Tikhonov’s or TSVD regularization method, LSC allows us to stabilize the inverse problem by including more physical information. The latter is introduced through a covariance function characterizing the observations, the parameters, and the functional link between them. One of the advantages of the LSC method is that it does not require any regularization parameter. First, we showed that, for the island of Haiti, the near field can extend until 24° around a GNSS station. Secondly, we proved that the hydrology-induced vertical deformation is part of the GNSS vertical displacement over the island. Finally, we demonstrated that the LSC may be used as a method to estimate TWS variations in dense GNSS network area. [less ▲]

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See detailDECIPHERING THE ROLE OF CELL-CELL COMMUNICATION IN HEALTH AND DISEASE - USING SYSTEMS BIOLOGY BASED COMPUTATIONAL MODELLING
Singh, Kartikeya UL

Doctoral thesis (2023)

Cell-cell communication plays a significant role in shaping the functionality of the cells. Communication between the cells is also responsible for maintaining the physiological state of the cells and the ... [more ▼]

Cell-cell communication plays a significant role in shaping the functionality of the cells. Communication between the cells is also responsible for maintaining the physiological state of the cells and the tissue. Therefore, it is important to study the different ways by which cell-cell communication impacts the functional state of cells. Alterations in cell-cell communication can contribute to the development of disease conditions. In this thesis, we present two computational tools and a study to explore the different aspects of cell-cell communication. In the first manuscript, FunRes was developed to leverage the cell-cell communication model to investigate functional heterogeneity in cell types and characterize cell states based on the integration of interand intra-cellular signalling. This tool utilizes a combination of receptors and transcription factors (TFs) based on the reconstructed cell-cell communication network to split the cell types into functional states. The tool was applied to the TabulaMurisSenis atlas to discover functional cell states in both young and old mouse datasets. In addition, we compared our tool with state-of-the-art tools and validated the cell states using available markers from the literature. Secondly, we studied the evolution of gene expression in developing astrocytes under normal and inflammatory conditions. We characterized these cells using both transcriptional and chromatin accessibility data which were integrated to reconstruct the gene regulatory networks (GRNs) specific to the condition and timepoints. The GRNs were then topologically analyzed to identify key regulators of the developmental process under both normal and inflammatory conditions. In the final manuscript, we developed a computational tool that identified regulators of allergy and tolerance in a mouse model. The tool works by first reconstructing the cell-cell communication network and then analyzing the network for feedback loops. These feedback loops are important as they contribute to the sustenance of the tissue’s state. Identification of the feedback loops allows for the discovery of important molecules by comparative analysis of these feedback loops between various conditions. In summary, this thesis encompasses various ways of cellular regulation using cell-cell communication in a tissue. These studies contribute to a better understanding of the role cell-cell communication plays in health and disease along with the identification of therapeutic targets to design novel strategies against diseases [less ▲]

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See detailUniversal Breakdown of Kibble-Zurek Scaling in Fast Quenches across a Phase Transition
Zeng, Hua-Bi; Xia, Chuan-Yin; Del Campo Echevarria, Adolfo UL

in Physical Review Letters (2023)

Detailed reference viewed: 36 (2 UL)