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See detailA Journey Through Android App Analysis: Solutions and Open Challenges
Klein, Jacques UL

in International Symposium on Advanced Security on Software and Systems (2021, June)

Users can today download a wide variety of apps ranging from simple toy games to sophisticated business-critical apps. They rely on these apps daily to perform diverse tasks, some of them related to ... [more ▼]

Users can today download a wide variety of apps ranging from simple toy games to sophisticated business-critical apps. They rely on these apps daily to perform diverse tasks, some of them related to sensitive information such as their finance or health. Ensuring high-quality, reliable, and secure apps is thus key. In the TruX research group of the interdisciplinary center for Security, Reliability, and Trust (SnT) of the University of Luxembourg, we are working for about 10 years to deliver practical techniques, tools, and other artifacts (such as repositories) making the analysis of Android apps possible. In this paper, we will briefly introduce our key contributions in both (1) Android app static analysis to detect security issues, and (2) Android Malware Detection with machine learning. We will conclude by listing several open challenges that we are currently facing towards improving the analysis and security of Android apps. [less ▲]

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See detail"[M]a défense, c’est mon éclat". Conjurer l’oubli face à la mort ? Figurations de l'oubli comme mort symbolique dans la correspondance staëlienne
Saintes, Laetitia UL

in Travaux et recherches de l'Institut Benjamin Constant (2021), 18

Cet article entend examiner au départ de la correspondance de Germaine de Staël, ainsi que de Dix années d'exil, toutes les occurrences de cette peur de l'oubli qui la touche dès qu'est ordonné son exil à ... [more ▼]

Cet article entend examiner au départ de la correspondance de Germaine de Staël, ainsi que de Dix années d'exil, toutes les occurrences de cette peur de l'oubli qui la touche dès qu'est ordonné son exil à quarante lieues de Paris. L'écrivaine clôt en effet nombre de ses lettres en demandant à ses correspondants de ne pas l'oublier, et évoque à de nombreuses reprises sa peur de ne plus être remémorée (de ses amis comme de l'opinion) si elle en venait à ne plus lutter publiquement contre la mesure d'exil qui la frappe. En ce sens, conjurer l'oubli revient chez elle à conjurer la mort symbolique qui serait la sienne dès lors qu'elle accepterait son sort d'exilée sans discussion ; le présent article envisage les modalités selon lesquelles se joue cette peur de l'oubli comme d'une mort symbolique. [less ▲]

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See detailEmulating the gut–liver axis: Dissecting the microbiome's effect on drug metabolism using multiorgan-on-chip models
Lucchetti, Mara UL; Kaminska, Mathilda; Kehinde Oluwasegun, Aina et al

in Current Opinion in Endocrine and Metabolic Research (2021)

The homeostatic relationship between the gut, its microbiome, and the liver is crucial for the regulation of drug metabolism processes. Gut microbes are known to influence human health and disease by ... [more ▼]

The homeostatic relationship between the gut, its microbiome, and the liver is crucial for the regulation of drug metabolism processes. Gut microbes are known to influence human health and disease by enhancing food metabolism and providing a first line of defense against pathogens. In addition to this, the gut microbiome also plays a key role in the processing of exogenous pharmaceutical compounds. Modeling the highly variable luminal gut environment and understanding how gut microbes can modulate drug availability or induce liver toxicity remains a challenge. However, microfluidics-based technologies such as organ-on-chips could overcome current challenges in drug toxicity assessment assays because these technologies are able to better recapitulate complex human responses. Efforts are being made to create in vitro multiorgan platforms, tailored for an individual patient's microbial background. These platforms could be used as a tool to predict the effect of the gut microbiome on pharmacokinetics in a personalized way. [less ▲]

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See detailLeitfaden zum Zitieren, Erstellen einer Literaturliste und zum Aufbau wissenschaftlicher Arbeiten im Bereich Erziehungswissenschaften im deutschsprachigen Raum
Baltes, Christel UL; Flammang, Manou Laure UL; Michelini, Nadia et al

Learning material (2021)

Dieser grundlegende Leitfaden zum Verfassen von wissenschaftlichen Arbeiten im Bereich Erziehungswissneschaften im deutschsprachigen Raum zeichnet sich aus durch klare Anleitungen und sinngebende ... [more ▼]

Dieser grundlegende Leitfaden zum Verfassen von wissenschaftlichen Arbeiten im Bereich Erziehungswissneschaften im deutschsprachigen Raum zeichnet sich aus durch klare Anleitungen und sinngebende Illustrationen. Das Dokument ist entstanden durch eine Kooperation von Dozentinnen und Studentinnen des Bacheor in Sozial- und Erziehungswissenschaften (BSSE) der Universität Luxemburg. [less ▲]

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See detailApplying synchronization in branch and trunk bus networks: an experimental analysis
Laskaris, Georgios; Rinaldi, Marco; Viti, Francesco UL

Scientific Conference (2021, June)

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See detailReliability of network-wide traffic management
Rinaldi, Marco; Viti, Francesco UL

Scientific Conference (2021, June)

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See detailObservability based data-fusion cascading filtering for urban network flow estimation
Rinaldi, Marco; Viti, Francesco UL

in IEEE Xplore (2021, June)

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See detailVerbessern Entspannungsverfahren die Interozeptionsfähigkeit? – Eine 1-wöchige Intervention
Dierolf, Angelika UL; Gräfin von Königsmark, Benita; Gorji, Lilia et al

Poster (2021, June)

Verbessern Entspannungsverfahren die Interozeptionsfähigkeit? – Eine 1-wöchige Intervention Interozeption, die Wahrnehmung und Verarbeitung körpereigener Signale, ist ein zentraler Aspekt von Gesundheit ... [more ▼]

Verbessern Entspannungsverfahren die Interozeptionsfähigkeit? – Eine 1-wöchige Intervention Interozeption, die Wahrnehmung und Verarbeitung körpereigener Signale, ist ein zentraler Aspekt von Gesundheit und Krankheit. Eine gestörte Interozeptionsfähigkeit zeigt sich bei verschieden psychischen Erkrankungen, wie Depression oder auch Essstörungen. In der vorliegenden Studie wurde an 76 gesunden Studenten untersucht, ob sich die interozeptive Genauigkeit und das interozeptive Bewusstsein durch eine 5-tägige körperbezogene Imaginationsübung per Audiodatei verbessern lassen. Als Kontrollbedingung diente eine nicht-körperbezogene Traumreise und nicht-entspannungsbezogene Podcasts der Serie ZeitWissen. Die Erhebung erfolgte online. Vor und nach der 5-tägigen Intervention wurden interozeptive Genauigkeit (Interoceptive Accuracy Scale (IAs)) und interozeptives Bewusstsein (Multidimensional Assessment of Interoceptive Awareness (MAIA)) erfasst. Erste Ergebnisse zeigen eine interventionsunabhängige Zunahme der interozeptiven Genauigkeit und des interozeptiven Bewusstsein nach allen Interventionen. Unabhängig von Intervention und Messzeitpunkt scheinen allerdings depressive, Angst- und Stresssymptome, gemessen mit Depressions-Angst-Stress-Skalen (DASS), sowie psychische Belastungen durch die aktuelle Covid-19 Pandemie insbesondere interozeptives Bewusstsein und in geringerem Ausmaß interozeptive Genauigkeit negativ zu beeinflussen. Die wöchentliche Häufigkeit, mit der generell eigene Achtsamkeits- oder Entspannungsübungen durchgeführt werden, wirkt sich positiv auf das interozeptive Bewusstsein aus. Insgesamt scheint Interozeptionsfähigkeit auch durch eine körperbezogene kurze, intensive imaginative Entspannungsübung in gesunden jungen Erwachsenen nicht verbessert zu werden, im Gegensatz zu regelmäßigem Yoga-, Mediations- oder Achtsamkeitstraining, welches interozeptives Bewusstsein positiv beeinflusst. [less ▲]

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See detailCognitive distraction from pain: An fMRI study on the role of age and executive functions
Rischer, Katharina Miriam UL; Dierolf, Angelika UL; González-Roldán, Ana M. et al

Scientific Conference (2021, June)

Completing a cognitive task has been shown to be a powerful strategy to reduce concurrent pain. This reduction in pain is assumed to result from a competition between the painful stimulus and the ... [more ▼]

Completing a cognitive task has been shown to be a powerful strategy to reduce concurrent pain. This reduction in pain is assumed to result from a competition between the painful stimulus and the distractive task for attentional and executive resources mediated by the prefrontal cortex (PFC), a region that is particularly affected by age-related grey matter atrophy. In the present study, we investigated the role of age-related changes in gray matter volume and executive functions in modulating the efficacy of distraction from pain. In a first session, young and older adults completed a battery of neuropsychological tests. In a second session, we acquired functional brain images while participants completed a working memory task with two levels of cognitive load (low vs. high load) and concurrently received individually adjusted heat stimuli (innocuous vs. painful) to their lower arm. While we found no age-related differences in the distraction effect size on the behavioural level, young adults showed a larger neural distraction effect in several regions involved in pain processing, including the insula, caudate and midcingulate cortex. Interestingly, older adults with better executive functions, particularly, better inhibitory control abilities, showed a larger neural distraction effect in the insula, thalamus and primary somatosensory cortex, and more activation in frontal clusters during the high load task. Taken together, these findings suggest that age alters the neural mechanisms underlying cognitive distraction from pain, and that the magnitude of these changes may be dependent on the preservation of executive functions. [less ▲]

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See detailCultural identity in the context of migration – The case of Portuguese first generation immigrants in Luxembourg and their second generation children
Albert, Isabelle UL; Barros, Stephanie

Scientific Conference (2021, June)

While first generation immigrants carry a cultural heritage to their receiving country, their children are confronted with different cultural influences during their formative years. How does this so ... [more ▼]

While first generation immigrants carry a cultural heritage to their receiving country, their children are confronted with different cultural influences during their formative years. How does this so-called second-generation experience their cultural identities compared to their parents? To tackle this question, the present study focused on first- and second-generation Portuguese migrants living in Luxembourg. The sample comprises n = 72 PT young adult children (mean age M = 28.2, SD = 7.9; 61.1% female) who participated in the FNR-funded IRMA-project together with their parents (n = 70 PT mothers and n = 65 PT fathers). An adapted version of the bicultural identity orientation scale was employed to assess three dimensions of bicultural identity - compatible, conflicted and frame-switching. We examined patterns of identity constructions of first and second generation by use of cluster analysis, resulting in four profiles: blended, alternating, separated and ambivalent biculturals. Whereas second generation young adults were represented in each typology, parents were mostly found in the alternating or separated clusters. Clusters of parents and their children will be compared and factors contributing to parent-child congruence/incongruence identified. Results will be discussed considering regulatory processes of subjective well-being and different migration experiences in light of generation and age. [less ▲]

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See detailRecent Developments and Overview of the Country and Practitioner’s Reports
Cole, Mark David UL

in European Data Protection Law Review (2021), 7(2021), 217-220

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See detailPain Processing in Older Age – Evidence from Event-Related Potentials
Dierolf, Angelika UL; Rischer, Katharina Miriam UL; González-Rolán, Ana Maria et al

Scientific Conference (2021, June)

Aging is known to affect neurobiological and physiological aspects of pain perception and has been associated with reduced pain sensitivity and a deterioration of descending pain inhibitory mechanisms. To ... [more ▼]

Aging is known to affect neurobiological and physiological aspects of pain perception and has been associated with reduced pain sensitivity and a deterioration of descending pain inhibitory mechanisms. To investigate age differences in neural electrophysiological correlates of pain processing, we induced acute pain in healthy older (60 yrs+) and younger adults (18 to 35 yrs), using short transdermal electrical pulses administered to the inner forearm, with individually adjusted stimulation intensities. Participants received alternating blocks of painful and non-painful control stimulation and rated the intensity and unpleasantness of each stimulus on two visual analog scales. Pain-related evoked potentials were recorded with a 64-channel EEG. Preliminary results indicate that younger and older participants rated painful stimuli more intensive and unpleasant compared to the control stimulation, with older adults showing a slight habituation over time. In younger adults, ERP amplitudes (N2, P2 P3) of painful stimulation were enhanced compared to non- painful stimulation. In contrast, older participants showed generally reduced ERPs, no difference between pain and non-painful stimulation and by tendency longer latencies for painful stimulation. This suggests that nociceptive neural processing is altered in aging, while the reported pain perception is unaffected. Given that aging is also associated with a decline of cognitive functions and PFC volume and activity changes, this could have implications for the efficacy of cognitive pain modulation. Altogether, our results highlight the need for a deeper understanding of the mechanisms underlying pain processing in older adults, and how these age-related changes affect (cognitive) pain treatments in this population. [less ▲]

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See detailDistraction from Pain: An fMRI Study on the Role of Age-related Changes in Executive Functions
Rischer, Katharina Miriam UL; González-Roldán, Ana M.; Montoya, Pedro et al

Scientific Conference (2021, June)

Even though aging is associated with increased and prolonged episodes of pain, little is known about potential age-related changes in the "top-down" modulation of pain, such as cognitive distraction from ... [more ▼]

Even though aging is associated with increased and prolonged episodes of pain, little is known about potential age-related changes in the "top-down" modulation of pain, such as cognitive distraction from pain. The hypoalgesic effect of distraction results from a competition for attentional and executive resources mediated by the prefrontal cortex (PFC). Given that age-related grey matter atrophy is particularly prominent in the PFC, older adults may benefit less from distraction to reduce pain than young adults. The aim of this study was to investigate the influence of aging on task-related hypoalgesia and its neural mechanisms, with a focus on the role of executive functions in distraction from pain. 64 participants (32 young adults: 26.69 ± 4.14 years; 32 older adults: 68.28 ± 7.00 years) first completed a battery of neuropsychological tests. In a second session, we administered a pain distraction paradigm while functional brain images were acquired. In this paradigm, participants completed a low (0-back) and a high (2-back) load condition of a working memory task while receiving either innocuous or painful heat stimuli to their lower arm. To control for age-related differences in sensitivity to pain and perceived task difficulty, stimulus intensity and task speed were individually calibrated. Both age groups showed significantly reduced activity in a network of regions involved in pain processing when performing the high compared to the low load distraction task; however, young adults showed a larger neural distraction effect in several of these regions, including the insula, caudate and midcingulate cortex. Moreover, in older adults, better executive functions – in particular inhibitory control abilities – were associated with a larger neural distraction effect in the insula, thalamus and primary somatosensory cortex, and with more activation in several prefrontal cortex regions during the high load task. These findings clearly demonstrate that the top-down control of pain is altered by age and could explain the higher vulnerability of older adults to developing chronic pain. Moreover, our findings suggest that the assessment of executive functions may be a useful tool for predicting the efficacy of cognitive pain modulation strategies in older adults. [less ▲]

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See detailDark solitons in a trapped gas of long-range interacting bosons
Beau, M.; Del Campo Echevarria, Adolfo UL; Frantzeskakis, D. J. et al

in Physical Review X (2021)

We consider the interplay of repulsive short-range and long-range interactions in the dynamics of dark solitons, as prototypical coherent nonlinear excitations in a trapped quasi-1D Bose gas. Upon ... [more ▼]

We consider the interplay of repulsive short-range and long-range interactions in the dynamics of dark solitons, as prototypical coherent nonlinear excitations in a trapped quasi-1D Bose gas. Upon examining the form of the ground state, both the existence of the solitary waves and their stability properties are explored and corroborated by direct numerical simulations. We find that single- and multiple-dark-soliton states can exist and are generically robust in the presence of long-range interactions. We analyze the modes of vibration of such excitations and find that their respective frequencies are significantly upshifted as the strength of the long-range interactions is increased. Indeed, we find that a prefactor of the long-range interactions considered comparable to the trap strength may upshift the dark soliton oscillation frequency by an order of magnitude, in comparison to the well established one of /√2 in a trap of frequency . [less ▲]

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