Reconnaissance de forme sur les bases de données iconographiques

in Bouzeghoub, Mokrane; Mosseri, Rémy (Eds.) Les Big Data à découvert (2017)

»Literatur der Moderne«.

in Berndt, Frauke; Goebel, Eckart (Eds.) Handbuch Literatur & Psychoanalyse (2017)

La reconnaissance des entités nommées dans les bases numériques de chartes médiévales en latin : le cas du Corpus Burgundiae Medii Aevi (xe-xiiie siècle)

in Medievales (2017), 73

Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms.

in Scientific reports (2017), 7(1), 15901

Targeting mitochondria is a powerful strategy for pathogens to subvert cell physiology and establish infection. Helicobacter pylori is a bacterial pathogen associated with gastric cancer development that ... [more ▼]

Targeting mitochondria is a powerful strategy for pathogens to subvert cell physiology and establish infection. Helicobacter pylori is a bacterial pathogen associated with gastric cancer development that is known to target mitochondria directly and exclusively through its pro-apoptotic and vacuolating cytotoxin VacA. By in vitro infection of gastric epithelial cells with wild-type and VacA-deficient H. pylori strains, treatment of cells with purified VacA proteins and infection of a mouse model, we show that H. pylori deregulates mitochondria by two novel mechanisms, both rather associated with host cell survival. First, early upon infection VacA induces transient increase of mitochondrial translocases and a dramatic accumulation of the mitochondrial DNA replication and maintenance factors POLG and TFAM. These events occur when VacA is not detected intracellularly, therefore do not require the direct interaction of the cytotoxin with the organelle, and are independent of the toxin vacuolating activity. In vivo, these alterations coincide with the evolution of gastric lesions towards severity. Second, H. pylori also induces VacA-independent alteration of mitochondrial replication and import components, suggesting the involvement of additional H. pylori activities in mitochondria-mediated effects. These data unveil two novel mitochondrial effectors in H. pylori-host interaction with links on gastric pathogenesis. [less ▲]

Blackout analysis of small cone-shaped reentry vehicles

in Journal of Thermophysics and Heat Transfer (2017), 31(2), 269--282

The high temperatures associated with the hypersonic reentry process lead to an increase in the collisions between molecules, which may result in the disruption of the electronic structure, producing free ... [more ▼]

The high temperatures associated with the hypersonic reentry process lead to an increase in the collisions between molecules, which may result in the disruption of the electronic structure, producing free electrons and ions. This production of free electrons and ions creates a plasma or ionized flowfield around the vehicle that is known to degrade the quality of radio-wave signal propagation, leading to a loss of communication or "blackout." This study involves performing hypersonic computational fluid dynamics simulations in the commercial software CFD++ with a bluntnosed cone geometry at different flight conditions to predict how and when ground communication can be achieved to aid in the design of an alert transmitter, which is an extension of aircraft collision-avoidance system technology. Computational results show that a small blunt-nosed cone geometry has decreased ionization regions as the cone angle decreases due to a shifting of the reaction zone further downstream. As a result, higher freestream velocities have less of an impact in determining the location for an antenna, and communicating along the stagnation line is seen to be independent of cone angle. [less ▲]

Setup of the yaskawa sda10f robot for industrial applications, using ros-industrial

in Advances in Automation and Robotics Research in Latin America (2017)

Cats parallel great apes and corvids in motor self-regulation, but size matters

Poster (2017)

We tested domestic cats in the cylinder task, and found that they perform better ifthe cylinder is larger. We also found that their highest performance parallels that ofgreat apes and corvids, which are ... [more ▼]

We tested domestic cats in the cylinder task, and found that they perform better ifthe cylinder is larger. We also found that their highest performance parallels that ofgreat apes and corvids, which are known as the best performing animals on this task.The cylinder task is used to test animals’ motor self-regulation. Recently a large-scalestudy tested 36 species on the task and found that absolute brain size correlatedwith the performance; with great apes as top performers. Another study showedthat corvids perform as good as great apes despite having smaller absolute brainsize. We questioned whether average brained animals have as poor motor self-regulation as suggested, as it appears highly maladaptive; instead the results couldbe a reflection of the sensorimotor set-up of different species in relation to thematerials used. No cats have been tested on the task before.Eight adult domestic cats participated in four versions of the task. We manipulatedthe size and materials, with two large (18.5 cm diameter) and two small (9.5 cmdiameter) cylinders, out of glass and plastic respectively. Each condition comprisedof two phases. First, a subject learned to retrieve a reward from an opaque cylinder(5 trials), and after a 24-hour delay was tested on a transparent cylinder (10 trials). Aretrieval of the reward without touching the cylinder’s front counted as a successfultrial.The success rate differed between conditions, and was highest (98,75) for the “smallplastic” condition. There was a significant main effect of the cylinder size on thesuccess rate [F(1,7)=64.06, p <0.001]. We discuss these results, as they call intoquestion whether the large-scale study took into account the sensorimotor architecture of each species, and more importantly, whether the task alwaysmeasures motor self-regulation. [less ▲]

Title: Board members in squeeze-out transactions: an event study analysis

in International Journal of Economics and Accounting (2017), 8(1), 43-60

In this study, we investigate the role of board members in German squeeze-out transactions by applying the event study methodology. We find that a dismissal of a management board member is associated with ... [more ▼]

In this study, we investigate the role of board members in German squeeze-out transactions by applying the event study methodology. We find that a dismissal of a management board member is associated with lower cumulative abnormal returns in the period of three months preceding the squeeze-out announcement. This indicates that minority shareholders receive a lower compensation if management board members are dismissed prior to the squeeze-out announcement. Though we are cautious to draw inferences from this finding, we follow other scholars (e.g., Daske et al., 2010) and suggest that majority shareholders exploit their superior status and use its power opportunistically. We furthermore explore the effects of directors' dealings in a squeeze-out transaction. We find that if stock purchases take place in a period of one year preceding the announcement, abnormal returns tend to be lower in the run-up period and higher on the announcement date. [less ▲]

Od wyczerpanego do samoświadomego pojęcia muzyki

in Audiosfera. Koncepcje – Badania – Praktyki (2017), 1(5), 4-20

Was ist politische Musik?

in Darmstädter Beiträge zur Neuen Musik (2017), 24