Last 7 days
Bookmark and Share    
Full Text
Peer Reviewed
See detailDevelopment and Application of an LC-MS/MS Untargeted Exposomics Method with a Separated Pooled Quality Control Strategy
Frigerio, Gianfranco UL; Moruzzi, Camilla; Mercadante, Rosa et al

in Molecules (2022), 27(8), 2580

Pooled quality controls (QCs) are usually implemented within untargeted methods to improve the quality of datasets by removing features either not detected or not reproducible. However, this approach can ... [more ▼]

Pooled quality controls (QCs) are usually implemented within untargeted methods to improve the quality of datasets by removing features either not detected or not reproducible. However, this approach can be limiting in exposomics studies conducted on groups of exposed and nonexposed subjects, as compounds present at low levels only in exposed subjects can be diluted and thus not detected in the pooled QC. The aim of this work is to develop and apply an untargeted workflow for human biomonitoring in urine samples, implementing a novel separated approach for preparing pooled quality controls. An LC-MS/MS workflow was developed and applied to a case study of smoking and non-smoking subjects. Three different pooled quality controls were prepared: mixing an aliquot from every sample (QC-T), only from non-smokers (QC-NS), and only from smokers (QC-S). The feature tables were filtered using QC-T (T-feature list), QC-S, and QC-NS, separately. The last two feature lists were merged (SNS-feature list). A higher number of features was obtained with the SNS-feature list than the T-feature list, resulting in identification of a higher number of biologically significant compounds. The separated pooled QC strategy implemented can improve the nontargeted human biomonitoring for groups of exposed and nonexposed subjects. [less ▲]

Detailed reference viewed: 24 (0 UL)
Full Text
See detailLuxembourg and the creation of the European single currency - Lessons from the History
Danescu, Elena UL

Presentation (2022, April 15)

In political terms, European integration and multilateral cooperation enabled Luxembourg to become an equal partner in the decision-making processes and leadership of European organizations. In economic ... [more ▼]

In political terms, European integration and multilateral cooperation enabled Luxembourg to become an equal partner in the decision-making processes and leadership of European organizations. In economic terms, these features gave the country the tools it needed to forge a development model that could underpin the creative growth of its social market economy, while preserving the majority of its vital interests—particularly the steel industry and the financial centre—over the long term. Focusing primarily on the 1970 Werner Report, which served as a blueprint for the European single currency - the euro - the presentation examines a key period in European integration history and one of the major European achievements of Luxembourg and of Pierre Werner (29 December 1913– 24 June 2002), former Prime Minister, Finance Minister and Foreign Minister of Luxembourg, who left his mark on the future of his country and is unanimously recognised as one of the architects of Economic and Monetary Union. [less ▲]

Detailed reference viewed: 36 (0 UL)
Full Text
Peer Reviewed
See detailReplicating the Kinora: 3D Modelling and Printing as Heuristics in Digital Media History
Van der Heijden, Tim; Wolf, Claude UL

in Journal of Digital History (2022)

This article reflects on the Kinora replica project, an interdisciplinary collaboration between the Luxembourg Centre for Contemporary and Digital History (C2DH) and the Department of Engineering (DoE) of ... [more ▼]

This article reflects on the Kinora replica project, an interdisciplinary collaboration between the Luxembourg Centre for Contemporary and Digital History (C2DH) and the Department of Engineering (DoE) of the University of Luxembourg. Combining historical inquiry with a hands-on and technical approach – involving the latest 3D modelling and desktop manufacturing engineering techniques – it provides insights into the process of making a working replica of the Kinora motion picture technology from the early 1900s. [less ▲]

Detailed reference viewed: 46 (1 UL)
Full Text
Peer Reviewed
See detailConciliatory views, higher-order disagreements, and defeasible logic
Knoks, Aleks UL

in Synthese (2022), 200(2), 1-23

Conciliatory views of disagreement say, roughly, that it’s rational for you to become less confident in your take on an issue in case you find out that an epistemic peer’s take on it is the opposite ... [more ▼]

Conciliatory views of disagreement say, roughly, that it’s rational for you to become less confident in your take on an issue in case you find out that an epistemic peer’s take on it is the opposite. Their intuitive appeal notwithstanding, there are well-known worries about the behavior of conciliatory views in scenarios involving higher-order disagreements, which include disagreements over these views themselves and disagreements over the peer status of alleged epistemic peers. This paper does two things. First, it explains how the core idea behind conciliatory views can be expressed in a defeasible logic framework. The result is a formal model that’s particularly useful for thinking about the behavior of conciliatory views in cases involving higher-order disagreements. And second, the paper uses this model to resolve three paradoxes associated with disagreements over epistemic peerhood. [less ▲]

Detailed reference viewed: 22 (0 UL)
Full Text
See detailHeilsgeschichte aus dem Osten
Ganschow, Inna UL; Majerus, Stephanie

Article for general public (2022)

Der russische Ultranationalismus kann als „politische Religion“ aufgefasst werden. Beeinflusst dieser ideologische Überbau russischsprachige Gemeinschaften in Luxemburg?

Detailed reference viewed: 27 (1 UL)
See detailLëtzebuerger Mathematikerin bei der Weltraumagence ESA
Palmirotta, Guendalina UL

Speeches/Talks (2022)

Eng Lëtzebuerger Mathematikerin schafft zanter e puer Woche fir d'europäesch Weltraumagence zu Darmstadt. Déi jonk Fra entwéckelt Modeller fir d'Wieder am Weltall virauszesoen, fir esou d ... [more ▼]

Eng Lëtzebuerger Mathematikerin schafft zanter e puer Woche fir d'europäesch Weltraumagence zu Darmstadt. Déi jonk Fra entwéckelt Modeller fir d'Wieder am Weltall virauszesoen, fir esou d' Satellittesystemer viru Sonnestierm ze schützen. De Weltall passionéiert zanter, datt et d'Mënschheet gëtt. D’Dr. Guenda Palmirotta ass Mathematikerin a huet sech fréi fir dat interesséiert, wat ausserhalb vun der Äerd geschitt. Mam Job bei der Europäescher Weltraumagence geet en Dram an Erfëllung. Zu Darmstadt entwéckelt d'Lëtzebuergerin Modeller fir d’Weltraumwieder virauszesoen. Bestëmmt gëtt dëst vun der Sonn an de Sonnestierm, déi kennen entstoen, déi fir Satellittesystemer e Problem kënnen duerstellen. Ee vun den Ziler ass et, an den nächste Joren d’Previsioune méi präzis ze maachen, ma och méi wäit am viraus kënne viraussoen, wat geschitt. Konkret ginn d’Modeller elo schonn agesat, fir d’Astronauten op der Internationaler Weltraumstatioun ze schützen. Zu Darmstadt huet d'ESA een neien Iwwerwaachungszentral, wou nieft dem Weltraumwieder och aner Elementer vun der Weltraumsécherheet am A behale ginn. Esou zum Beispill de Weltraumschrott, mëttlerweil gëtt et vill Satellitten, déi net fonctionéieren a mat Aktive kéinte kollidéieren. Mat mathematesche Modeller sollen déi aktiv Satellitte gewarnt ginn a se esou hir Positioun fréizäiteg kënnen änneren. [less ▲]

Detailed reference viewed: 33 (0 UL)
Full Text
Peer Reviewed
See detailDemand and Interference Aware Adaptive Resource Management for High Throughput GEO Satellite Systems
Abdu, Tedros Salih UL; Kisseleff, Steven UL; Lagunas, Eva UL et al

in IEEE Open Journal of the Communications Society (2022)

The scarce spectrum and power resources, the inter-beam interference, together with the high traffic demand, pose new major challenges for the next generation of Very High Throughput Satellite (VHTS ... [more ▼]

The scarce spectrum and power resources, the inter-beam interference, together with the high traffic demand, pose new major challenges for the next generation of Very High Throughput Satellite (VHTS) systems. Accordingly, future satellites are expected to employ advanced resource/interference management techniques to achieve high system spectrum efficiency and low power consumption while ensuring user demand satisfaction. This paper proposes a novel demand and interference aware adaptive resource management for geostationary (GEO) VHTS systems. For this, we formulate a multi-objective optimization problem to minimize the total transmit power consumption and system bandwidth usage while matching the offered capacity with the demand per beam. In this context, we consider resource management for a system with full-precoding, i.e. all beams are precoded; without precoding, i.e. no precoding is applied to any beam; and with partial precoding, i.e. only some beams are precoded. The nature of the problem is non-convex and we solve it by jointly using the Dinkelbach and Successive Convex Approximation (SCA) methods. The simulation results show that the proposed method outperforms the benchmark schemes. Specifically, we show that the proposed method requires low resource consumption, low computational time, and simultaneously achieves a high demand satisfaction. [less ▲]

Detailed reference viewed: 20 (1 UL)
Full Text
Peer Reviewed
See detailCommission Delegated Regulation (EU) 2022/30 Supplementing Directive 2014/53/EU on Radio Equipment: Strengthening Cybersecurity, Privacy and Personal Data Protection of Wireless Devices
Chiara, Pier Giorgio UL

in European Data Protection Law Review (2022), 8(1), 103-107

This contribution highlights how the Delegated Regulation (EU) 2022/30 - activating the essential requirements of Article 3(3)(d), (e) and (f) of Directive 2014/53/EU on radio equipment (RED) - will ... [more ▼]

This contribution highlights how the Delegated Regulation (EU) 2022/30 - activating the essential requirements of Article 3(3)(d), (e) and (f) of Directive 2014/53/EU on radio equipment (RED) - will enhance and complement existing cybersecurity and privacy & data protection EU legal frameworks while strengthening the (cyber)security of wireless (IoT) devices. [less ▲]

Detailed reference viewed: 77 (3 UL)
Full Text
Peer Reviewed
See detailAutonomy and the social dilemma of online manipulative behavior
Botes, Wilhelmina Maria UL

in AI and Ethics (2022)

Persuasive online technologies were initially designed and used to gain insights into the online behavior of individuals to personalize advertising campaigns in an effort to influence people and convince ... [more ▼]

Persuasive online technologies were initially designed and used to gain insights into the online behavior of individuals to personalize advertising campaigns in an effort to influence people and convince them to buy certain products. But recently, these technologies have blurred the lines and morphed into technologies that covertly and gradually manipulate people into attaining a goal that is predetermined by the algorithm and disregards the decision-making rights of the individual. This may lead to people exercising decisions that do not align with their personal values and beliefs, and rob them of their autonomy—an ethical principle, in the absence of which the application of these technologies may be unethical. However, not all technologies that are persuasive are necessarily manipulative which require the careful consideration of a couple of elements to determine whether or not technologies are manipulative and ultimately whether their application is ethical or not. In this article, we analyze the ethical principle of autonomy and unpack the underlying elements of this ethical principle which must be considered to determine whether the application of a technology is ethical or not in the context of it being persuasive or manipulative. [less ▲]

Detailed reference viewed: 28 (3 UL)
See detailSpotlight on Young Researchers: Nature’s shapes as mathematical challenges
Palmirotta, Guendalina UL

Article for general public (2022)

In nature, we see hyperbolic forms in corals, flatworms, and many other species of reef organisms, such as sponges and kelps. The hyperbolic spaces are also of interest for mathematicians, who are looking ... [more ▼]

In nature, we see hyperbolic forms in corals, flatworms, and many other species of reef organisms, such as sponges and kelps. The hyperbolic spaces are also of interest for mathematicians, who are looking to prove the solvability of invariant systems of differential equations in unusual spaces such as these. [less ▲]

Detailed reference viewed: 27 (1 UL)
Full Text
Peer Reviewed
See detailPRINS: Scalable Model Inference for Component-based System Logs
Shin, Donghwan UL; Bianculli, Domenico UL; Briand, Lionel UL

in Empirical Software Engineering (2022)

Behavioral software models play a key role in many software engineering tasks; unfortunately, these models either are not available during software development or, if available, quickly become outdated as ... [more ▼]

Behavioral software models play a key role in many software engineering tasks; unfortunately, these models either are not available during software development or, if available, quickly become outdated as implementations evolve. Model inference techniques have been proposed as a viable solution to extract finite state models from execution logs. However, existing techniques do not scale well when processing very large logs that can be commonly found in practice. In this paper, we address the scalability problem of inferring the model of a component-based system from large system logs, without requiring any extra information. Our model inference technique, called PRINS, follows a divide-and-conquer approach. The idea is to first infer a model of each system component from the corresponding logs; then, the individual component models are merged together taking into account the flow of events across components, as reflected in the logs. We evaluated PRINS in terms of scalability and accuracy, using nine datasets composed of logs extracted from publicly available benchmarks and a personal computer running desktop business applications. The results show that PRINS can process large logs much faster than a publicly available and well-known state-of-the-art tool, without significantly compromising the accuracy of inferred models. [less ▲]

Detailed reference viewed: 228 (16 UL)
Full Text
Peer Reviewed
See detailSustainability and Circular Economy in Learning Factories – Case Studies
Weyand, Astrid; Thiede, Sebastian; Mangers, Jeff UL et al

in SSRN (2022, April 11)

Since the mitigation of climate change is one of the biggest challenges to face on a global scale, the topic has become more relevant also in industrial context. Learning factories have proven to be ... [more ▼]

Since the mitigation of climate change is one of the biggest challenges to face on a global scale, the topic has become more relevant also in industrial context. Learning factories have proven to be suitable environments to address and convey competencies to tackle industrial challenges in an interactive way. Hence, several learning factories are already dealing with sustainability topics in various use cases. This paper strives to present a state of the art of sustainability and circular economy in learning factories. Therefore, a classification framework is developed based on the state of the art of several learning factories and existing literature regarding the topic. This framework is then used to systematically describe the different activities regarding sustainability and circular economy that are currently ongoing in learning factories worldwide. This can be used to get an idea about the different aspects of the topic and how to address them, but furthermore also offers assistance to identify “blind spots” which could and should be addressed in learning factories in the future. [less ▲]

Detailed reference viewed: 39 (3 UL)
Full Text
See detailUnsichtbares sichtbar machen
Scuto, Denis UL; Harnoncourt, Julia UL

Article for general public (2022)

Detailed reference viewed: 38 (0 UL)
Full Text
Peer Reviewed
See detailCreating positive learning experiences with technology: A field study on the effects of user experience for digital concept mapping
Rohles, Björn UL; Backes, Susanne UL; Fischbach, Antoine UL et al

in Heliyon (2022), 8(4),

Learning and assessment are increasingly mediated by digital technologies. Thus, learners’ experiences with these digital technologies are growing in importance, as they might affect learning and ... [more ▼]

Learning and assessment are increasingly mediated by digital technologies. Thus, learners’ experiences with these digital technologies are growing in importance, as they might affect learning and assessment. The present paper explores the impact of user experience on digital concept mapping. It builds on user experience theory to explain variance in the intention to use digital concept mapping tools and in concept map-based assessment scores. Furthermore, it identifies fulfillment of psychological needs as an important driver of positive experiences. In a field study in three schools and a university (N = 71), we tested two concept mapping prototypes on computers and tablets. We found that user experience is a significant factor explaining variance in intention to use. User experience also explained variance in three out of four concept mapping scores on tablets, potentially related to the lower pragmatic quality of the tablet prototypes. Fulfillment of psychological needs strongly affected perceptions of different qualities of user experience with digital concept mapping. These results indicate that user experience needs to be considered in digital concept mapping to provide a positive and successful environment for learning and assessment. Finally, we discuss implications for designers of digital learning and assessment tools. [less ▲]

Detailed reference viewed: 25 (3 UL)
See detailHistoricising online virality
Schafer, Valerie UL

Presentation (2022, April 08)

This presentation aims to questions the methodologies and challenges related to an historical study of European online virality.

Detailed reference viewed: 70 (0 UL)
See detailReplicating the Kinora: 3D Modelling and Printing as Heuristics in Digital Media History
Wolf, Claude UL; van der Heijden, Tim

Computer development (2022)

The Kinora replica 3D model was produced in the context of the project "Doing Experimental Media Archaeology: Practice and Theory (DEMA)", funded by the Fonds National de la Recherche, Luxembourg (FNR ... [more ▼]

The Kinora replica 3D model was produced in the context of the project "Doing Experimental Media Archaeology: Practice and Theory (DEMA)", funded by the Fonds National de la Recherche, Luxembourg (FNR) (C18/SC/12703137): https://dema.uni.lu/. The Kinora replica project was the result of a collaboration between the Luxembourg Centre for Contemporary and Digital History (C2DH) and the Department of Engineering (DoE) of the University of Luxembourg. See for more information the article "Replicating the Kinora: 3D modelling and printing as heuristics in digital media history", published in the Journal of Digital History: https://journalofdigitalhistory.org/en/article/33pRxE2dtUHP [less ▲]

Detailed reference viewed: 124 (2 UL)
Full Text
See detailSEMKIS: A CONTRIBUTION TO SOFTWARE ENGINEERING METHODOLOGIES FOR NEURAL NETWORK DEVELOPMENT
Jahic, Benjamin UL

Doctoral thesis (2022)

Today, there is a high demand for neural network-based software systems supporting humans during their daily activities. Neural networks are computer programs that simulate the behaviour of simplified ... [more ▼]

Today, there is a high demand for neural network-based software systems supporting humans during their daily activities. Neural networks are computer programs that simulate the behaviour of simplified human brains. These neural networks can be deployed on various devices e.g. cars, phones, medical devices...) in many domains (e.g. automotive industry, medicine...). To meet the high demand, software engineers require methods and tools to engineer these software systems for their customers. Neural networks acquire their recognition skills e.g. recognising voice, image content...) from large datasets during a training process. Therefore, neural network engineering (NNE) shall not be only about designing and implementing neural network models, but also about dataset engineering (DSE). In the literature, there are no software engineering methodologies supporting DSE with precise dataset selection criteria for improving neural networks. Most traditional approaches focus only on improving the neural network’s architecture or follow crafted approaches based on augmenting datasets with randomly gathered data. Moreover, they do not consider a comparative evaluation of the neural network’s recognition skills and customer’s requirements for building appropriate datasets. In this thesis, we introduce a software engineering methodology (called SEMKIS) supported by a tool for engineering datasets with precise data selection criteria to improve neural networks. Our method considers mainly the improvement of neural networks through augmenting datasets with synthetic data. SEMKIS has been designed as a rigorous iterative process for guiding software engineers during their neural network-based projects. The SEMKIS process is composed of many activities covering different development phases: requirements’ specification; dataset and neural network engineering; recognition skills specification; dataset augmentation with synthetized data. We introduce the notion of key-properties, used all along the process in cooperation with a customer, to describe the recognition skills. We define a domain-specific language (called SEMKIS-DSL) for the specification of the requirements and recognition skills. The SEMKIS-DSL grammar has been designed to support a comparative evaluation of the customer’s requirements with the key-properties. We define a method for interpreting the specification and defining a dataset augmentation. Lastly, we apply the SEMKIS process to a complete case study on the recognition of a meter counter. Our experiment shows a successful application of our process in a concrete example. [less ▲]

Detailed reference viewed: 58 (11 UL)