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See detailThe human gut microbiome in health: establishment and resilience of microbiota over a lifetime
Greenhalgh, Kacy UL; Wilmes, Paul UL; Meyer, Kristen Michelle et al

in Environmental Microbiology (2016), 18(7), 21032116

With technological advances in culture-independent molecular methods, we are uncovering a new facet of our natural history by accounting for the vast diversity of microbial life which colonizes the human ... [more ▼]

With technological advances in culture-independent molecular methods, we are uncovering a new facet of our natural history by accounting for the vast diversity of microbial life which colonizes the human body. The human microbiome contributes functional genes and metabolites which affect human physiology and are, therefore, considered an important factor for maintaining health. Much has been described in the past decade based primarily on 16S rRNA gene amplicon sequencing regarding the diversity, structure, stability and dynamics of human microbiota in their various body habitats, most notably within the gastrointestinal tract (GIT). Relatively high levels of variation have been described across different stages of life and geographical locations for the GIT microbiome. These observations may prove helpful for the future contextualization of patterns in other body habitats especially in relation to identifying generalizable trends over human lifetime. Given the large degree of complexity and variability, a key challenge will be how to define baseline healthy microbiomes and how to identify features which reflect deviations therefrom in the future. In this context, metagenomics and functional omics will likely play a central role as they will allow resolution of microbiome-conferred functionalities associated with health. Such information will be vital for formulating therapeutic interventions aimed at managing microbiota-mediated health particularly in the GIT over the course of a human lifetime. [less ▲]

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See detailAcute stress influences the discrimination of complex scenes and complex faces in young healthy men
Paul, Marcus; Lech, Robert, K.; Scheil, Juliane et al

in Psychoneuroendocrinology (2016), 66

The stress-induced release of glucocorticoids has been demonstrated to influence hippocampal functions via the modulation of specific receptors. At the behavioral level stress is known to influence ... [more ▼]

The stress-induced release of glucocorticoids has been demonstrated to influence hippocampal functions via the modulation of specific receptors. At the behavioral level stress is known to influence hippocampus dependent long-term memory. In recent years, studies have consistently associated the hippocampus with the non-mnemonic perception of scenes, while adjacent regions in the medial temporal lobe were associated with the perception of objects, and faces. So far it is not known whether and how stress influences non-mnemonic perceptual processes. In a behavioral study, fifty male participants were subjected either to the stressful socially evaluated cold-pressor test or to a non-stressful control procedure, before they completed a visual discrimination task, comprising scenes and faces. The complexity of the face and scene stimuli was manipulated in easy and difficult conditions. A significant three way interaction between stress, stimulus type and complexity was found. Stressed participants tended to commit more errors in the complex scenes condition. For complex faces a descriptive tendency in the opposite direction (fewer errors under stress) was observed. As a result the difference between the number of errors for scenes and errors for faces was significantly larger in the stress group. These results indicate that, beyond the effects of stress on long-term memory, stress influences the discrimination of spatial information, especially when the perception is characterized by a high complexity. [less ▲]

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See detailNarrating the Time of Troubles in Polish School History Textbooks (1918–1989)
Venken, Machteld UL

in Cahiers du Monde Russe (2016), 57

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See detailSingle crystalline cylindrical nanowires – toward dense 3D arrays of magnetic vortices
Ivanov, Yurii P.; Chuvilin, Andrey; Gonzalez Vivas, Laura UL et al

in Scientific Reports (2016), 6

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See detailTesting for association between RNA-Seq and high-dimensional data
Rauschenberger, Armin UL; Jonker, Marianne A.; van de Wiel, Mark A. et al

in BMC Bioinformatics (2016), 17

Background: Testing for association between RNA-Seq and other genomic data is challenging due to high variability of the former and high dimensionality of the latter. Results: Using the negative binomial ... [more ▼]

Background: Testing for association between RNA-Seq and other genomic data is challenging due to high variability of the former and high dimensionality of the latter. Results: Using the negative binomial distribution and a random-effects model, we develop an omnibus test that overcomes both difficulties. It may be conceptualised as a test of overall significance in regression analysis, where the response variable is overdispersed and the number of explanatory variables exceeds the sample size. Conclusions: The proposed test can detect genetic and epigenetic alterations that affect gene expression. It can examine complex regulatory mechanisms of gene expression. The R package globalSeq is available from Bioconductor. [less ▲]

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See detailFrom meta-omics to microbial systems ecology: What to measure and what is there to learn?
Wilmes, Paul UL

Scientific Conference (2016, March)

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See detailIntégrer l´outil informatique dans le cours de mathématiques (Geogebra/Excel)
Kreis, Yves UL

Speeches/Talks (2016)

Utilisation de nouveaux outils dans le cours de mathématiques : sections SO,CM,CG.

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See detailBouddhisme et Franc-maçonnerie
Meyers, Christian UL

Conference given outside the academic context (2016)

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See detailPiecing together the puzzle: integrated omics of microbial consortia
Wilmes, Paul UL

Scientific Conference (2016, February)

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See detailFrom meta-omics to microbial systems ecology: What can we learn?
Wilmes, Paul UL

Presentation (2016, February)

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See detailTeaching about Europe: digital resources and tools
Gabellini, Marco UL; Klein, Francois UL; Mouton, Victoria UL

Speeches/Talks (2016)

The training workshop at the ‘Institut de formation de l'Éducation nationale’, entitled ‘Teaching about Europe: digital resources and tools’, was aimed at teachers in Luxembourg. The workshop particularly ... [more ▼]

The training workshop at the ‘Institut de formation de l'Éducation nationale’, entitled ‘Teaching about Europe: digital resources and tools’, was aimed at teachers in Luxembourg. The workshop particularly focused on the potential of the ‘MyPublications’ tool, available in the Digital Toolbox on cvce.eu. This tool enables teachers to reuse, customise and share the wide range of archive resources and explanatory articles available in the various collections on cvce.eu so that they can use them in a classroom setting by creating their own sequences of documents. [less ▲]

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See detailGagner sa vie au volant au risque de la perdre: Les pilotes automobiles européens (années 1920-1930)
Moreau, Sebastien UL

in Mouvement Social (2016), 254

This article deals with the emergence of a group of professional automobile pilots in Europe during the Interwar period. During the time, automobile racing was institutionalised and commercialised to a ... [more ▼]

This article deals with the emergence of a group of professional automobile pilots in Europe during the Interwar period. During the time, automobile racing was institutionalised and commercialised to a previously unknown extent, under the supervision of European automobile clubs, industrial groups and journalists. In this context, by following the trajectories of pilots, we study the conditions for exercising this practice – part sport, part social activity. These trajectories are mainly marked by a wide diversity due to the sport’s origins, at the crossroads of changes in bourgeois leisure activities and the unprecedented development of the automobile industry. On the roads and race tracks of Europe, racing team pilots came up against wealthy independent racers, forming a stratified population and a wide range of participants with diverse origins, mobility, motivations and compensation. In the representations of the period, the pilots became the icons of the triumph of the automobile, but they nevertheless took second stage to the industrial groups that employed and equipped them. In this European space that was driven across and appropriated, behind the sports competition that acted as a support, this situation gave rise to large-scale industrial competitions and strategies that benefited the sportsmen but also held them captive. [less ▲]

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See detailFigurationen zwischen Eis und Wüste – Textgebiete bei Franz Kafka. Von Vampiren und anderen Kreaturen aus der Zwischenzone.
Küpper, Achim UL

in Jahrbuch der Deutschen Schillergesellschaft (2016), 60

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