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See detailMeasurement invariance of the Positive Gains Scale in families of children with and without disabilities
Jess, Mikeda; Bailey, Tom; Pit-Ten Cate, Ineke UL et al

in Research in Developmental Disabilities (2020), 103

Background Despite the high frequency of case-control studies in the developmental disability literature, there is a paucity of research establishing the measurement equivalence of instruments used, and ... [more ▼]

Background Despite the high frequency of case-control studies in the developmental disability literature, there is a paucity of research establishing the measurement equivalence of instruments used, and particularly those relating to positive perceptions and experiences in family disability research. Aims The present study sought to establish measurement invariance for the Positive Gains Scale (PGS) across 1219 mothers of children with developmental disabilities, 234 mothers of children with spina bifida/hydrocephalus, and 157 mothers of children without disabilities. Methods and Procedures A three-step test for measurement invariance across the three groups was conducted using Multigroup Confirmatory Factor Analysis. Outcomes and Results Loadings between the three groups were invariant, suggesting the criteria to assume metric invariance was met. However, the assumption of scalar invariance was not met, suggesting that item intercepts differed between the three groups. Conclusions and Implications Our findings suggest that the PGS cannot be meaningfully used to compare outcomes between mothers of children with developmental disabilities and other mothers. These findings may have wider implications for research utilising well-being measures to make comparisons with carers of children with developmental disabilities. [less ▲]

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See detailAttitudes towards Multiculturalism in Luxembourg: Measurement Invariance and Factor Structure of the Multicultural Ideology Scale
Stogianni, Maria UL; Murdock, Elke UL; He, Jia et al

E-print/Working paper (2020)

The present study examined the dimensionality and the measurement invariance of the Multicultural Ideology Scale (MCI; Berry & Kalin, 1995), and mean differences across different cultural groups within ... [more ▼]

The present study examined the dimensionality and the measurement invariance of the Multicultural Ideology Scale (MCI; Berry & Kalin, 1995), and mean differences across different cultural groups within the multilingual, multicultural context of Luxembourg. With 47% of the citizens being non-nationals, minority and majority are increasingly difficult to define and Luxembourg becomes a unique context to study attitudes towards diversity. Our sample included 1488 participants from diverse ethnic backgrounds who completed the survey in German, French or English. In contrast to previous findings, our analyses revealed a two-dimensional structure, distinguishing between positive and negative attitudes towards multiculturalism. The factor structure was partially invariant across ethnocultural groups: Configural and metric invariance were established across natives and non-natives, scalar invariance only across gender groups. Natives and male participants reported more negative attitudes towards multiculturalism. We discuss the importance of assessing measurement invariance and provide recommendations to improve the assessment of psychological multiculturalism. [less ▲]

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See detailGuidelines for Operationalizing Policy Coherence for Development (PCD) as a Methodology for the Design and Implementation of Sustainable Development Strategies
Koff, Harlan UL; Challenger, Antony; Portillo, Israel

in Sustainability (2020), 12(4055), 1-23

Policy Coherence for Development (PCD) is considered a pillar of the 2030 Sustainable Development Agenda. It aims to promote whole of government approaches to sustainable development. Despite its ... [more ▼]

Policy Coherence for Development (PCD) is considered a pillar of the 2030 Sustainable Development Agenda. It aims to promote whole of government approaches to sustainable development. Despite its prominence in development cooperation discussions, many national development professionals or stakeholders have not heard of PCD, indicating that its effectiveness is significantly limited. This article contends that the impact of PCD has not been maximized because it has been presented as a political objective or a policy tool by multilateral organizations and their member states. Instead, the article argues that PCD should be implemented as a methodology that can be adopted by domestic government and non-governmental actors alike, in order to understand trade-offs and co-benefits within and between policy sectors, thus promoting a participative approach. I-GAMMA is a research project in Mexico that examines data-driven public policy in order to promote PCD. It is based on in-depth reviews of policy documents and interviews with development actors. It is committed to open data, evidence-based policymaking, and collaborative dialogue between academics, government officials, and representatives of civil society organizations in sustainable development discussions. In the results section of this article, the project proposes participative PCD as a methodology for policy analysis through which a plurality of actors can identify mechanisms that either reinforce or undermine sustainable development strategies. This section then applies the methodology to the governance of protected natural areas in Mexico. The discussion section and the conclusions highlight the relevance of this approach for participative policymaking in sustainable development. [less ▲]

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See detailStudent translanguaging: insights into resource combinations and reflections of classroom practices
Degano, Sarah UL

Presentation (2020, May 15)

This presentation adopts a multimodal perspective on translanguaging. It focusses on the extent to which multilingual pupils’ translanguaging practices provide insights into the semiotic repertoires of ... [more ▼]

This presentation adopts a multimodal perspective on translanguaging. It focusses on the extent to which multilingual pupils’ translanguaging practices provide insights into the semiotic repertoires of the students and connect to the classroom practices of their learning environment as well as to those of the larger community. [less ▲]

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See detailMISCAST: MIssense variant to protein StruCture Analysis web SuiTe
Iqbal, Sumaiya; Hoksza, David UL; Pérez-Palma, Eduardo et al

in Nucleic Acids Research (2020)

Human genome sequencing efforts have greatly expanded, and a plethora of missense variants identified both in patients and in the general population is now publicly accessible. Interpretation of the ... [more ▼]

Human genome sequencing efforts have greatly expanded, and a plethora of missense variants identified both in patients and in the general population is now publicly accessible. Interpretation of the molecular-level effect of missense variants, however, remains challenging and requires a particular investigation of amino acid substitutions in the context of protein structure and function. Answers to questions like ‘Is a variant perturbing a site involved in key macromolecular interactions and/or cellular signaling?’, or ‘Is a variant changing an amino acid located at the protein core or part of a cluster of known pathogenic mutations in 3D?’ are crucial. Motivated by these needs, we developed MISCAST (missense variant to protein structure analysis web suite; http://miscast.broadinstitute.org/). MISCAST is an interactive and user-friendly web server to visualize and analyze missense variants in protein sequence and structure space. Additionally, a comprehensive set of protein structural and functional features have been aggregated in MISCAST from multiple databases, and displayed on structures alongside the variants to provide users with the biological context of the variant location in an integrated platform. We further made the annotated data and protein structures readily downloadable from MISCAST to foster advanced offline analysis of missense variants by a wide biological community. [less ▲]

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See detailFlucht- und Wanderungsbewegungen in Ostbelgien 1944/45
Brüll, Christoph UL

Scientific Conference (2020, May 13)

Detailed reference viewed: 23 (1 UL)
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See detailGastric interoception and gastric myoelectrical activity in bulimia nervosa and binge eating disorder
van Dyck, Zoé UL; Schulz, André UL; Blechert, Jens et al

in International Journal of Eating Disorders (2020)

Objective: Identifying factors that control food intake is crucial to the understanding and treatment of eating disorders characterized by binge eating. In healthy individuals, stomach distension plays an ... [more ▼]

Objective: Identifying factors that control food intake is crucial to the understanding and treatment of eating disorders characterized by binge eating. In healthy individuals, stomach distension plays an important role in the development of satiation, but gastric sensations might be overridden in binge eating. The present study investigated the perception of gastric signals (i.e., gastric interoception) and gastric motility in patients experiencing binge eating episodes, i.e. bulimia nervosa (BN) and binge-eating disorder (BED). Method: Twenty-nine patients with BN or BED (ED group) and 32 age-, sex-, and BMI-matched healthy controls (HC group) participated in the study. The onset of satiation and stomach fullness were assessed using a novel 2-step water load test (WLT-II). Gastric myoelectrical activity (GMA) was measured by electrogastrography (EGG) before and after ingestion of non-caloric water. Results: Individuals in the ED group drank significantly more water until reporting satiation during the WLT-II. The percentage of normal gastric myoelectrical power was significantly smaller in the ED group compared to HC, and negatively related to the number of objective binge-eating episodes per week in bulimic patients. Power in the bradygastria range was greater in ED than in HC subjects. Discussion: Patients with EDs have a delayed response to satiation compared to HC participants, together with abnormal GMA. Repeated binge eating episodes may induce disturbances to gastric motor function. [less ▲]

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See detailHybrid User Pairing for Spectral and Energy Efficiencies in Multiuser MISO-NOMA Networks with SWIPT
Nguyen, Toan-Van; Nguyen, van Dinh UL; Costa, Daniel Benevides Da et al

in IEEE Transactions on Communications (2020), 68(8), 4874-4890

In this paper, we propose a novel hybrid user pairing (HUP) scheme in multiuser multiple-input single-output nonorthogonal multiple access networks with simultaneous wireless information and power ... [more ▼]

In this paper, we propose a novel hybrid user pairing (HUP) scheme in multiuser multiple-input single-output nonorthogonal multiple access networks with simultaneous wireless information and power transfer. In this system, two information users with distinct channel conditions are optimally paired while energy users perform energy harvesting (EH) under non-linearity of the EH circuits. We consider the problem of jointly optimizing user pairing and power allocation to maximize the overall spectral efficiency (SE) and energy efficiency (EE) subject to userspecific quality-of-service and harvested power requirements. A new paradigm for the EE-EH trade-off is then proposed to achieve a good balance of network power consumption. Such design problems are formulated as the maximization of nonconcave functions subject to the class of mixed-integer non-convex constraints, which are very challenging to solve optimally. To address these challenges, we first relax binary pairing variables to be continuous and transform the design problems into equivalent non-convex ones, but with more tractable forms. We then develop low-complexity iterative algorithms to improve the objectives and converge to a local optimum by means of the inner approximation framework. Simulation results show the convergence of proposed algorithms and the SE and EE improvements of the proposed HUP scheme over state-of-the-art designs. In addition, the effects of key parameters such as the number of antennas and dynamic power at the BS, target data rates, and energy threshold, on the system performance are evaluated to show the effectiveness of the proposed schemes in balancing resource utilization. [less ▲]

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See detailEuropeanizing Universities: Expanding and Consolidating Networks of the Erasmus Mundus Joint Master Degree Programme (2004–2017)
Marques, Marcelo; Zapp, Mike UL; Powell, Justin J W UL

in Higher Education Policy (2020)

The Europeanization of higher education has gained considerable scope and momentum over the past quarter century. Whereas the coordinative Bologna process, with soft governance mechanisms, have ... [more ▼]

The Europeanization of higher education has gained considerable scope and momentum over the past quarter century. Whereas the coordinative Bologna process, with soft governance mechanisms, have facilitated standardization across countries, European Commission funding programs targeted universities more directly. The Erasmus Mundus Joint Degree Programme, as an incentive-based program, epitomizes the dynamics of such European funding management. Notably, it has established expanding university networks across Europe and unique new tertiary degrees that facilitate student mobility. Applying social network analysis to 561 participating universities through several program cycles, we longitudinally examine three key patterns in the program’s development: the expansion of the programme, the consolidation of networks, and the participation of and coordination by central universities in these processes. Program participation increased considerably across cycles, even as established networks were consolidated, largely through re- accreditation of established programs. Moreover, we identify those universities that assume a central position in the inter-organizational structure of this international program. These universities actively facilitate the evolving Europeanization of higher education by strengthening inter-university networks via a signature EU program. [less ▲]

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See detailFear and Stock Price Bubbles
Lehnert, Thorsten UL

in PLoS ONE (2020), 15 (5)(e0233024), 1-11

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See detailPriLok:Citizen-protecting distributed epidemic tracing
Esteves-Verissimo, Paulo UL; Decouchant, Jérémie UL; Volp, Marcus UL et al

E-print/Working paper (2020)

Contact tracing is an important instrument for national health services to fight epidemics. As part of the COVID-19 situation, many proposals have been made for scaling up contract tracing capacities with ... [more ▼]

Contact tracing is an important instrument for national health services to fight epidemics. As part of the COVID-19 situation, many proposals have been made for scaling up contract tracing capacities with the help of smartphone applications, an important but highly critical endeavor due to the privacy risks involved in such solutions. Extending our previously expressed concern, we clearly articulate in this article, the functional and non-functional requirements that any solution has to meet, when striving to serve, not mere collections of individuals, but the whole of a nation, as required in face of such potentially dangerous epidemics. We present a critical information infrastructure, PriLock, a fully-open preliminary architecture proposal and design draft for privacy preserving contact tracing, which we believe can be constructed in a way to fulfill the former requirements. Our architecture leverages the existing regulated mobile communication infrastructure and builds upon the concept of "checks and balances", requiring a majority of independent players to agree to effect any operation on it, thus preventing abuse of the highly sensitive information that must be collected and processed for efficient contact tracing. This is enforced with a largely decentralised layout and highly resilient state-of-the-art technology, which we explain in the paper, finishing by giving a security, dependability and resilience analysis, showing how it meets the defined requirements, even while the infrastructure is under attack. [less ▲]

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See detailDe la déclaration du 9 mai 1950 vers l’Union européenne
Danescu, Elena UL; da Silva, Joana UL; Backes, Yuriko et al

in Danescu, Elena; da Silva, Joana; Europe Direct Information Centre de l'Université du Luxembourg, (Eds.) et al De la déclaration du 9 mai 1950 vers l’Union européenne (2020)

Destiné à un large public de tous horisons, cette publications originale traite de la signification historique de la Déclaration prononcée le 9 mai 1950 par Robert Schuman, de ses échos dans le présent ... [more ▼]

Destiné à un large public de tous horisons, cette publications originale traite de la signification historique de la Déclaration prononcée le 9 mai 1950 par Robert Schuman, de ses échos dans le présent, ainsi que des liens de Robert Schuman avec le Luxembourg et du rôle du Grand-Duché dans la construction européenne. Une section distincte est consacrée à la Maison de Robert Schuman située à Clausen sur laquelle l'Université du Luxembourg veille depuis 2016, le Luxembourg Centre for Contemporary and Digital History (C²DH). Une chronologie retrace les étapes-clé du proessus de la construction européenne. [less ▲]

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See detail"Un texte qui a changé le monde"
Danescu, Elena UL

Article for general public (2020)

L’Union européenne plonge ses racines dans la Seconde Guerre mondiale (1939-1945), le conflit le plus meurtrier de l’histoire de l’humanité. Alors que l’Europe tente de se reconstruire, des tensions ... [more ▼]

L’Union européenne plonge ses racines dans la Seconde Guerre mondiale (1939-1945), le conflit le plus meurtrier de l’histoire de l’humanité. Alors que l’Europe tente de se reconstruire, des tensions politiques fracturent le continent entre l’Est et l’Ouest et la guerre froide naissante fait resurgir le spectre d’une nouvelle confrontation. Mais comment forger une paix durable entre les adversaires d’hier ? Le problème principal réside dans la relation entre la France et l'Allemagne, ennemies héréditaires, qui se sont fait par trois fois la guerre (1870, 1914 et 1939). Le chemin de la paix passe par la réconciliation de ces deux puissances antagonistes pour ensuite pouvoir rassembler toutes les nations libres d'Europe afin de bâtir ensemble une « communauté de destin ». C’est la vision que partagent deux personnalités françaises aux rôles complémentaires — Jean Monnet (1888-1979), commissaire général du Plan, et Robert Schuman (1886-1963), ministre des Affaires étrangères [less ▲]

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See detailTransforming Unitary States into Federations: Path-Dependent Construction of Political Identities in Belgium and Lebanon
Poirier, Philippe UL; Farhat, Nadim UL; Bourbeau, Philippe et al

in Publius: the Journal of Federalism (2020), pjaa007

The theory of congruence in comparative federalism holds that institutional design will, eventually, reflect societal divisions by transferring central powers to new, autonomous entities. While this model ... [more ▼]

The theory of congruence in comparative federalism holds that institutional design will, eventually, reflect societal divisions by transferring central powers to new, autonomous entities. While this model helps to understand why many divided societies adopt federalism, it cannot explain why only certain unitary states transform into federal ones while others do not. We use a historical institutionalism approach to identify the critical junctures in the trajectory of two prominent plural polities, Belgium and Lebanon. We suggest that the politicization of identities during initial stages of state-building plays a major role in the transformation of a unitary state into a federation—which occurs in the former but not in the latter of our cases. The current contrast in both consociational democracies is explained here as a legacy of the late nineteenth century, which set in motion decisive logics of public governance that direct institutional dynamics until today. [less ▲]

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See detailEmerging Techniques and Applications for 5G Networks and Beyond
Nguyen, van Dinh UL; Duong, Trung Q; Vien, Quoc-Tuan

in Mobile Networks and Applications (2020)

Detailed reference viewed: 46 (4 UL)
See detailStudying Events: Feedback on a Pedagogical Experiment
Schafer, Valerie UL

Presentation (2020, May 05)

Based on the experience of the Winter School I conducted for 2 years on Web archives at the university of Luxembourg and which involved research on European events and Europan history by Master’s students ... [more ▼]

Based on the experience of the Winter School I conducted for 2 years on Web archives at the university of Luxembourg and which involved research on European events and Europan history by Master’s students, I will draw some methodological conclusions (interesting topics, difficulties in grasping participation, typology of transnational events with regard to Web archives, issues of visual studies and transmedia studies...). [less ▲]

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See detailContextualising and engaging with Web domains
Schafer, Valerie UL

Presentation (2020, May 05)

This presentation suggests concrete avenues both to contextualize research on web domains and domain names (e.g. collaboration with the Afnic in France and use of its web archives to retrieve the price of ... [more ▼]

This presentation suggests concrete avenues both to contextualize research on web domains and domain names (e.g. collaboration with the Afnic in France and use of its web archives to retrieve the price of a domain name, its policy for allocating domain names, the number of domain names it allocated with regards to the domain names retrieved in web archives, etc.) but also to create public engagement with this topic (identifying the first web page in each country, the most represented twitter accounts in web archives, etc.). [less ▲]

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See detailTowards the routine use of in silico screenings for drug discovery using metabolic modelling
Bintener, Tamara Jean Rita UL; Pires Pacheco, Maria Irene UL; Sauter, Thomas UL

in Biochemical Society Transactions (2020)

Currently, the development of new effective drugs for cancer therapy is not only hindered by development costs, drug efficacy, and drug safety but also by the rapid occurrence of drug resistance in cancer ... [more ▼]

Currently, the development of new effective drugs for cancer therapy is not only hindered by development costs, drug efficacy, and drug safety but also by the rapid occurrence of drug resistance in cancer. Hence, new tools are needed to study the underlying mechanisms in cancer. Here, we discuss the current use of metabolic modelling approaches to identify cancer-specific metabolism and find possible new drug targets and drugs for repurposing. Furthermore, we list valuable resources that are needed for the reconstruction of cancer-specific models by integrating various available datasets with genome-scale metabolic reconstructions using model-building algorithms. We also discuss how new drug targets can be determined by using gene essentiality analysis, an in silico method to predict essential genes in a given condition such as cancer and how synthetic lethality studies could greatly benefit cancer patients by suggesting drug combinations with reduced side effects. [less ▲]

Detailed reference viewed: 44 (0 UL)