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See detailSoft law, effectiveness of fundamental rights and migration: how effective are migrants’ fundamental rights in an era of European governance
Mavrouli, Roila UL

in Current Challenges in Migration Policy and Law, Edited by Emília Lana de Freitas Castro and Sergio Maia Tavares, Published in London, England, ISBN: 978-1-910781-77-7 (2020)

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See detailKatrin Becker, Was tun Sie?
Becker, Katrin UL

in forum für Politik, Gesellschaft und Kultur (2020), 402

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See detailIdentification of pathogenic variant enriched regions across genes and gene families
Perez-Palma, Eduardo; May, Patrick UL; Iqbal, Sumaiya et al

in Genome Research (2020), 30(1), 62-71

Missense variant interpretation is challenging. Essential regions for protein function are conserved among gene family members, and genetic variants within these regions are potentially more likely to ... [more ▼]

Missense variant interpretation is challenging. Essential regions for protein function are conserved among gene family members, and genetic variants within these regions are potentially more likely to confer risk to disease. Here, we generated 2,871 gene family protein sequence alignments involving 9,990 genes and performed missense variant burden analyses to identify novel essential protein regions. We mapped 2,219,811 variants from the general population into these alignments and compared their distribution with 76,153 missense variants from patients. With this gene family approach, we identified 465 regions enriched for patient variants spanning 41,463 amino acids in 1,252 genes. As a comparison, testing the same genes individually we identified less patient variant enriched regions involving only 2,639 amino acids and 215 genes. Next, we selected de novo variants from 6,753 patients with neurodevelopmental disorders and 1,911 unaffected siblings, and observed an 8.33-fold enrichment of patient variants in our identified regions (95% C.I.=3.90-Inf, p-value = 2.72x10-11). Using the complete ClinVar variant set, we found that missense variants inside the identified regions are 106-fold more likely to be classified as pathogenic in comparison to benign classification (OR = 106.15, 95% C.I = 70.66-Inf, p-value < 2.2 x 10-16). All pathogenic variant enriched regions (PERs) identified are available online through the “PER viewer” a user-friendly online platform for interactive data mining, visualization and download. In summary, our gene family burden analysis approach identified novel pathogenic variant enriched regions in protein sequences. This annotation can empower variant interpretation. [less ▲]

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See detailA Multi-Hop Broadcast Wave Approach for Floating Car Data Collection in Vehicular Networks
Turcanu, Ion UL; Salvo, Pierpaolo; Baiocchi, Andrea et al

in Vehicular Communications (2020)

Inter-Vehicle Communication (IVC) is bringing connected and cooperative mobility closer to reality. Vehicles today are able to produce huge amounts of information, known in the literature as Floating Car ... [more ▼]

Inter-Vehicle Communication (IVC) is bringing connected and cooperative mobility closer to reality. Vehicles today are able to produce huge amounts of information, known in the literature as Floating Car Data (FCD), containing status information gathered from sensing the internal condition of the vehicle and the external environment. Adding networking capabilities to vehicles allows them to share this information among themselves and with the infrastructure. Collecting real-time FCD information from vehicles opens up the possibility of having access to an enormous amount of useful information that can boost the development of innovative services and applications in the domain of Intelligent Transportation System (ITS). In this paper we propose several solutions to efficiently collect real-time FCD information in Dedicated Short-Range Communication (DSRC)-enabled Vehicular Ad Hoc Networks (VANETs). The goal is to improve the efficiency of the FCD collection operation while keeping the impact on the DSRC communication channel as low as possible. We do this by exploiting a slightly modified version of a standardized data dissemination protocol to create a backbone of relaying vehicles that, by following local rules, generate a multi-hop broadcast wave of collected FCD messages. The proposed protocols are evaluated via realistic simulations under different vehicular densities and urban scenarios. [less ▲]

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See detailComportement suicidaire des adolescents au Luxembourg
Catunda, Carolina UL

Conference given outside the academic context (2020)

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See detailChapter 16 - Cognitive factors associated with gaming disorder
Billieux, Joël UL; Potenza, Marc N.; Maurage, Pierre et al

in Verdejo-Garcia, Antonio (Ed.) Cognition and Addiction (2020)

There is substantial clinical and public health evidence that video gaming, particularly online gaming, can become excessive and lead to psychological distress and functional impairment. This has led to ... [more ▼]

There is substantial clinical and public health evidence that video gaming, particularly online gaming, can become excessive and lead to psychological distress and functional impairment. This has led to the inclusion of gaming disorder as an official mental condition in the International Classification of Diseases, 11th Edition (ICD-11; World Health Organization, 2019). Psychological models recognize the importance of cognitive factors to explain the initiation, development, and maintenance of problematic gaming behaviors. This chapter will summarize some of the known cognitive factors associated with problem gaming and gaming disorder. These cognitions will be divided into two broad categories: (1) cognitive deficits (e.g., impaired executive functioning, hazardous decision-making, or deliberative processes) and (2) cognitive biases (e.g., attentional biases, cognitive distortions, dysfunctional cognitions). This chapter will review and synthesize available research findings and highlight their clinical implications for gaming disorder. The limitations of the research base are considered and some potential avenues for future research are proposed. [less ▲]

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See detailCVH Malach – Centrum vizuální historie Konference a workshop o novém přístupu a využití video databáze Fortunoff
Bronec, Jakub UL

in Marginalia Historica (2020)

On May 18, I took part in a very interesting workshop organized by the Malach Centre for Visual History at the Faculty of Mathematics and Physics of the Charles University in Prague. This exceptional ... [more ▼]

On May 18, I took part in a very interesting workshop organized by the Malach Centre for Visual History at the Faculty of Mathematics and Physics of the Charles University in Prague. This exceptional association provides local access to the extensive digital archives of the USC Shoah Foundation - the Institute for Visual history and Education (USC), the Refugee Voices archive of the Association of Jewish Refugees and the testimony collection of the Jewish Holocaust Centre in Melbourne. Nevertheless, the workshop focused on the newly incorporated Fortunoff Video Archive (FVA) that belongs to the category of long-awaited ingestion, and the path to get a licence was more than difficult. The archive represents a new source for all scholars including me, but in this short comment, I would like to critically point out to several minor drawbacks. [less ▲]

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See detailEarly Language Education in Luxembourg
Kirsch, Claudine UL; Seele, Claudia

in Schwartz, Mila; Prošić-Santovac, Danijela (Eds.) International Handbook of early childhood education (2020)

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See detailFlexible language use in multilingual early childhood education in Luxembourg: Reflecting on its nature and functions
Kirsch, Claudine UL; Seele, Claudia

in Panagiotopoulou, Argyro; Rosen, Lisa; Strzykala, Jenna (Eds.) Inclusion, Education, and Translanguaging: How to Promote Social Justice in (Teacher) Education? (2020)

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See detailUnderstanding the Evolution of Android App Vulnerabilities
Gao, Jun UL; li, li; Bissyande, Tegawendé François D Assise UL et al

in IEEE Transactions on Reliability (2020)

The Android ecosystem today is a growing universe of a few billion devices, hundreds of millions of users and millions of applications targeting a wide range of activities where sensitive information is ... [more ▼]

The Android ecosystem today is a growing universe of a few billion devices, hundreds of millions of users and millions of applications targeting a wide range of activities where sensitive information is collected and processed. Security of communication and privacy of data are thus of utmost importance in application development. Yet, regularly, there are reports of successful attacks targeting Android users. While some of those attacks exploit vulnerabilities in the Android OS, others directly concern application-level code written by a large pool of developers with varying experience. Recently, a number of studies have investigated this phenomenon, focusing however only on a specific vulnerability type appearing in apps, and based on only a snapshot of the situation at a given time. Thus, the community is still lacking comprehensive studies exploring how vulnerabilities have evolved over time, and how they evolve in a single app across developer updates. Our work fills this gap by leveraging a data stream of 5 million app packages to re-construct versioned lineages of Android apps and finally obtained 28;564 app lineages (i.e., successive releases of the same Android apps) with more than 10 app versions each, corresponding to a total of 465;037 apks. Based on these app lineages, we apply state-of- the-art vulnerability-finding tools and investigate systematically the reports produced by each tool. In particular, we study which types of vulnerabilities are found, how they are introduced in the app code, where they are located, and whether they foreshadow malware. We provide insights based on the quantitative data as reported by the tools, but we further discuss the potential false positives. Our findings and study artifacts constitute a tangible knowledge to the community. It could be leveraged by developers to focus verification tasks, and by researchers to drive vulnerability discovery and repair research efforts. [less ▲]

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See detailExperimental and analytical analysis of the load-bearing capacity Pu of improved dry-stacked masonry
Chewe Ngapeya, Gelen Gael UL; Waldmann, Danièle UL

in Journal of Building Engineering (2020), 27

Dry-Stacked Masonry (DSM) as structural load-bearing element is still unexploited because of many factors including the early face-shell cracking, the impacts of the block imperfections on the wall load ... [more ▼]

Dry-Stacked Masonry (DSM) as structural load-bearing element is still unexploited because of many factors including the early face-shell cracking, the impacts of the block imperfections on the wall load-bearing capacity (Pu) and the lack of design code safely predicting Pu. Through experimental tests, this paper investigates a strategy for improving Pu of DSM by placing an additional horizontal contact layer on the top face of raw DSM blocks. The effect of four mixtures used to improve the raw DSM blocks has been investigated. Further, a mathematical model predicting Pu is proposed which takes into account the effects of the block imperfections. In the course of the investigation, 20 DSM wallets and 25 DSM prisms built with raw and improved DSM blocks were tested to failure under axial compression. In the former, the face-shell cracking load (Pcrack) and the load-bearing capacity (Pu) were recorded, while in the latter, the actual contact area was recorded in hundred full bed-joints using Prescale Fujifilm strips. The results showed that a contact layer of well-defined properties increased the actual contact area from 23% to 55% and improved Pu by 31,9%. The mathematical model for the raw DSM blocks predicts Pu with a mean accuracy of 93% and a standard deviation of 12% where the standards EN 1996-1-1 for mortared masonry exhibited a mean accuracy of 137% and a standard deviation of about 29%. Concerning the improved DSM blocks, the proposed model predicts Pu with a mean accuracy of 106% and a standard deviation of 10%, whereas the standards EN 1996-1-1 presents a mean accuracy of 124% and a standard deviation of 9%. [less ▲]

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See detailOvercome of bed-joint imperfections and improvement of actual contact in dry-stacked masonry
Chewe Ngapeya, Gelen Gael UL; Waldmann, Danièle UL

in Construction and Building Materials (2020)

Several researchers studied dry-stacked masonry walls (DSM) and inferred that the actual contact surface between the different block rows and the compressive strength in such walls are reduced by bed ... [more ▼]

Several researchers studied dry-stacked masonry walls (DSM) and inferred that the actual contact surface between the different block rows and the compressive strength in such walls are reduced by bed-joint imperfections as well as by height differences between different masonry blocks leading both to high stress concentration. This paper concentrates on the first type on imperfections. Through experimental tests, it analyses the influence of bed-joint roughness on the load bearing capacity and investigates a strategy to improve the load-bearing capacity of DSM by placing an additional horizontal layer on the top face of raw masonry blocks. First, different contact layers using conventional and auxetic materials were applied. Then 20 dry-stacked masonry prisms built with raw and improved masonry blocks were tested under axial compressive load until failure. Prescale Fujifilm strips were used to measure the actual contact in the bed-joints. Experimental tests show that the use of a contact layer with well-defined material properties enables firstly to increase the actual contact area in the bed-joints from 23% to 98% of the nominal contact area and secondly to increase the load-bearing capacity by 14 to 97%. In addition, the contact layer with an auxetic material shows a significant capacity in altering the lateral expansion in the block units. The outcomes show that although the bed joint roughness influences the stress distribution in a dry-stacked masonry block, a contact layer with well-defined material properties enables to overcome the roughness induced by the bed-joint imperfections. [less ▲]

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See detailL’édition de chartes à Luxembourg: de l’érudition aux nouvelles technologies (et vice-versa?)
Salemme, Timothy UL

in Bendheim, Amelie (Ed.) Tagungsband Mittelalter zwischen Faszination und Fortschritt (2020)

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See detailThe Migration-Development Nexus in the European Union Policy Framework – A Legal Perspective
Silga, Janine UL

Book published by Cambridge University Press (2020)

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See detailDer Wandel der jugendpolitischen Agenda und die Konsequenzen für die Konzeption der Lebensphase Jugend. Eine Analyse am Beispiel von Jugendpolitik in Luxemburg
Heinen, Andreas UL; Willems, Helmut UL

in Heinen, Andreas; Wiezorek, Christine; Willems, Helmut (Eds.) Entgrenzung der Jugend und Verjugendlichung der Gesellschaft. Zur Notwendigkeit einer »Neuvermessung« jugendtheoretischer Positionen (2020)

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See detailMigration, Asylum and EU Discrimination Law
Silga, Janine UL

in O’Cinneide, Colm; Ringelheim, Julie; Solanke, Iyiola (Eds.) Edward Elgar Research Handbook on European Anti-Discrimination Law (2020)

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See detailThe Ambiguity of the Migration and Development Nexus Policy Discourse: Perpetuating the Colonial Legacy?
Silga, Janine UL

in UCLA Journal of International Law and Foreign Affairs (2020)

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See detailBorder Experiences in Europe. Everyday Life - Working Life - Communication - Languages
Wille, Christian UL; Nienaber, Birte UL

in Wille, Christian; Nienaber, Birte (Eds.) Border Experiences in Europe. Everyday Life - Working Life - Communication - Languages (2020)

For a decade now, borders in Europe have been back on the political agenda. Border research has responded and is breaking new ground in thinking about and exploring borders. This book follows this ... [more ▼]

For a decade now, borders in Europe have been back on the political agenda. Border research has responded and is breaking new ground in thinking about and exploring borders. This book follows this development and strengthens a perspective that is interested in life realities and that focuses on everyday cultural experiences of borders. The authors reconstruct such experiences in the context of different forms of migration and mobility as well as language contact situations and are sensitive to the freedom of the participants. In this way, they empirically identify everyday cultural usage or appropriation strategies of borders as vastly different experiences of borders. The readers of this volume will gain insights into current developments in border research and life realities in Europe where borders are (made) relevant. With contributions by Christian Wille, Birte Nienaber, Carsten Yndigegn, Isabelle Pigeron-Piroth, Rachid Belkacem, Ursula Roos, Elisabeth Boesen, Ariela House, Ignacy Jóźwiak, Corinne Martin, Erika Kalocsányiová, Xosé-Afonso Álvarez, Konstanze Jungbluth, Florian Dost, Nicole Richter, Dominik Gerst [less ▲]

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