Integrated omics highlights keystone genes in community-wide metabolic networks

Poster (2013)

Der Versuchung widerstehen: Konfrontation mit hochkalorischen Nahrungsmitteln verbessert die Inhibitionsfähigkeit gezügelter Esser

Poster (2013)

Work Context and Career Development

Poster (2012, November)

Efeitos de contextos ambientais desfavoráveis na memória operacional

Poster (2012, October)

Há um crescente número de estudos indicando que o desempenho em tarefas de memória operacional (MO) depende fortemente do conhecimento e experiência prévios. Poucos estudos, entretanto, têm explorado ... [more ▼]

Há um crescente número de estudos indicando que o desempenho em tarefas de memória operacional (MO) depende fortemente do conhecimento e experiência prévios. Poucos estudos, entretanto, têm explorado diretamente o papel do ambiente social no desenvolvimento de habilidades de MO.Este estudo teve como objetivo investigar o impacto da experiência escolar e linguística do indivíduo em tarefas de MO verbal e visual. [less ▲]

Zwei Sprachen - Zwei Persönlichkeiten? Eine Vorstudie zur Idenitätskonstruktion im multikulturellen Luxembourg

Poster (2012, September 25)

Interkulturelle Kommunikation und interkulturelle Kompetenz in der Gesundheitsversorgung einer alternden Gesellschaft

Poster (2012, September)

A kinetic model and design principles study of cellular ROS defence and its failure in Parkinson’s disease

Poster (2012, August)

Mitochondrial generation of reactive oxygen species (ROS) is an unavoidable side effect of oxidative phosphorylation. To counteract the production of ROS, the cell employs two main strategies. The first ... [more ▼]

Mitochondrial generation of reactive oxygen species (ROS) is an unavoidable side effect of oxidative phosphorylation. To counteract the production of ROS, the cell employs two main strategies. The first one is to increase the consumption of ROS; this mechanism involves the superoxide dismutase enzyme and various antioxidants. The second strategy is to reduce the production of ROS by decreasing mitochondrial membrane potential and by increasing mitophagy. The precise tuning of the latter is crucial for cell survival: if mitophagy is too active, all mitochondria are lost and the cell suffers from reduced ATP capacity; if mitophagy is not active enough, dysfunctional mitochondria accumulate, more ROS is produced, and the cell undergoes unwanted programmed cell death. We hypothesize that a ROS-activated regulatory network is employed to coordinate the regulation of the rate of mitophagy, the expression of uncoupling proteins and the production of antioxidants, including SOD. In Parkinson’s disease (PD), the activities of several components of this regulatory network (e.g. KEAP1, PARK7, VDAC1, SQSTM1) are altered. This makes the cell susceptible to ROS damage. In the case of dopaminergic neurons, this effect can be particularly severe, because an additional pool of non-mitochondrial ROS generated during ROS-induced degradation of dopamine. In order to understand the functioning of the ROS-activated regulatory network in normal function and disease, we have built a kinetic model. Our model includes 39 species and 45 reactions, with 56 kinetic parameters, either fitted or obtained from literature. Our model allows the simulation of PD-related ROS generation and mitochondrial damage and the identification of the design principles underlying the functioning of the network; for example, showing and explaining the synergy between the down-regulation of both VDAC1 and PARK7 occurring during PD. The kinetic model has great potential use for better understanding of the pathophysiology of PD and for the suggestion of novel mitochondria-related PD treatments. [less ▲]

Das luxemburgischsprachige Oeuvre von Michel Rodange (1827-1876). Editionsphilologische und korpuslinguistische Analyse

Poster (2012, July)

Le chômage : une situation « normalisée » ? Etude menée auprès de demandeurs d’emploi séniors

Poster (2012, July)

La satisfaction au travail. Impact de quelques variables psycho-environnementales

Poster (2012, July)

Universal plane curves and Simpson moduli spaces of 1-dimensional sheaves

Poster (2012, June)

We show that the universal plane curve M of fixed degree d > 2 can be seen as a closed subvariety in a certain Simpson moduli space of 1-dimensional sheaves on a projective plane contained in the stable ... [more ▼]

We show that the universal plane curve M of fixed degree d > 2 can be seen as a closed subvariety in a certain Simpson moduli space of 1-dimensional sheaves on a projective plane contained in the stable locus. The universal singular locus coincides with the subvariety of M consisting of sheaves that are not locally free on their support. It turns out that the blow up of M along M' may be naturally seen as a compactification of M_B = M\M' by vector bundles (on support). [less ▲]

Do the mental number line and spatial sequence synesthesia share neural substrates? A patterned TMS study.

Poster (2012, May)

GOCE long-wavelength gravity field recovery from high-low satellite-to-satellite-tracking using the acceleration approach

Poster (2012, April)

How are achievement goals, academic self-concept, and academic attainment interrelated across time?

Poster (2012, April)

Elastic anomalies at the volume phase transition of aqueous PNIPAM solutions

Poster (2012, March 25)

Professionalisierung und subjektive Bezüge zum Wissen im Rahmen von LehrerInnenbildung

Poster (2012, March 13)

Entropy production in nonequilibrium steady states A different approach and an exactly solvable canonical model

Poster (2012, March)

Shifts of spatial attention cued by irrelevant numbers: Electrophysiological evidence from a target discrimination task

Poster (2012, February 10)

Fischer et al. demonstrated that a centrally presented number can shift attention to the left/right when its magnitude is small/large. Two electrophysiological studies described these attentional effects ... [more ▼]

Fischer et al. demonstrated that a centrally presented number can shift attention to the left/right when its magnitude is small/large. Two electrophysiological studies described these attentional effects as event-related potentials (ERPs) at centro-parietal sites. Since both studies used target detection tasks, it remains currently unknown whether similar results would be obtained with a discrimination task. We used ERPs to test whether digit cues also induce attention shifts when participants perform a feature-discrimination task on targets. ERPs were recorded whereas subjects discriminated the colour of lateral targets that were preceded by a central non-predictive digit. Analysis of cue-locked controlateral vs. ipsilateral ERP activity showed the emergence of early preparatory attention-directing components in parietal and frontal regions. Moreover, target-locked P1 components at occipito-parietal sites were significantly modulated by digit magnitude-target side congruency. These results demonstrate that irrelevant digit cues also bias sensory processing when embedded in a feature-discrimination task. [less ▲]

Machine learning techniques for atmospheric pollutant monitoring

Poster (2012, January 27)

Substrate dependence of the Raman 2D line of graphene

Poster (2012)

Teachers’ expectations of primary school children’s cognitive ability : Predictors and consequences.

Poster (2012)

Effect of viruses on bacterial community structure and single-cell carbon and nitrogen assimilation

Poster (2012)

A biomolecular isolation protocol for Eco-Systems Biology: How to isolate DNA, RNA, proteins and metabolites from a single unique sample

Poster (2012)

The Molecular Systems Biology approach based on the integration of omic datasets is hampered by the complexity, dynamic and heterogeneity of mixed microbial communities. In order to facilitate meaningful ... [more ▼]

The Molecular Systems Biology approach based on the integration of omic datasets is hampered by the complexity, dynamic and heterogeneity of mixed microbial communities. In order to facilitate meaningful data integration, individual biomolecular fractions need to be obtained from single unique samples. Our newly developed methodology allows for the isolation of high-quality genomic DNA, RNA, proteins and metabolites from single mixed microbial community samples (e.g. human faeces, freshwater filtrate), as well as from mammalian tissues. The framework lays the basis for standardized molecular (eco-)systematic studies on a range of different biological samples in the future. [less ▲]

Social representations and intervention practices in the field of professional (re-)integration in Luxembourg

Poster (2012)

Very high frequency of hereditary prosopagnosia among individuals with high intellectual abilities.

Poster (2012)

A Biomolecular Isolation Framework for Molecular Eco-Systems Biology

Poster (2012)

With the advent of high-throughput omic technologies, powerful and sensitive methods are available for the analysis of nucleic acid, protein and small molecule complements obtained from biological samples ... [more ▼]

With the advent of high-throughput omic technologies, powerful and sensitive methods are available for the analysis of nucleic acid, protein and small molecule complements obtained from biological samples. Molecular eco-systems biology studies based on the integration of genomic, transcriptomic, proteomic and metabolomic data are faced with major challenges arising from the complexity, dynamics and heterogeneity of mixed microbial consortia. In order to facilitate meaningful data integration, analysis and modeling, it is essential that biomolecular fractions obtained for high-throughput omic analyses are representative of single unique samples. We have developed a new methodological framework for the reproducible isolation of high-quality genomic DNA, large and small RNA, proteins, and polar and non-polar metabolites from single unique mixed microbial community samples. The methodology is based around reproducible cryogenic sample preservation and cell lysis. Metabolites are extracted first using organic solvents, followed by the sequential isolation of nucleic acids and proteins using chromatographic spin column technology. The methodology was validated by comparison to traditional dedicated and simultaneous biomolecular isolation methods. To prove the broad applicability of the methodology, we applied it to microbial consortia of biotechnological, environmental and medical interest. Importantly, the developed methodology will allow exploitation of the inherent heterogeneity and dynamics within microbial consortia through spatial and temporal sampling of biological systems to allow later deconvolution of community-wide, population-wide and individual-level processes using the generated omic data. This approach has the potential to identify associations between distinct biomolecules and which may provide pointers towards unravelling previously unknown metabolic processes. Finally, by providing a standardized workflow, the methodology lays the foundation for comparative eco-systematic studies of different natural microbial consortia in the future. [less ▲]

Essstörungen im Kindesalter: Die Vermeidend/Restriktive Essstörung im Selbstbericht

Poster (2012)

Analysis of critical transitions in Parkinson's disease

Poster (2011, December 12)

Background Parkinson’s disease is the most common neurodegenerative movement disorder and is clinically characterized by resting tremor, bradykinesia and cogwheel rigidity. The disease affects 1-2% of the ... [more ▼]

Background Parkinson’s disease is the most common neurodegenerative movement disorder and is clinically characterized by resting tremor, bradykinesia and cogwheel rigidity. The disease affects 1-2% of the global population with prevalence in the people above 65 years of age. The main pathological hallmark of Parkinson’s disease is a progressive loss of dopaminergic neurons in the substantia nigra. Therefore, one important challenge is to improve the understanding of regime shifts between health and disease states. Improving predictions of critical transitions triggering the onset of parkinsonian phenotypes could contribute to the improvement of preventive treatments. Methods Based on cellular models, we will use the mathematical concept of critical transitions to create a toolbox for potentially predicting tipping points towards cellular Parkinson’s disease phenotypes, e.g. mitochondrial dysfunction. Experimentally, we will induce and analyze potential critical transitions in the SH-SY5Y cell line. To do this, we will apply Parkinson’s disease relevant chemical and genetic perturbations and analyze multiple scales of the resulting temporal system behavior. We will combine high content imaging with genetic and biochemical data. A significant informatics challenge arises from the aim to perform the analysis of high time-resolved 3D imaging data. We are therefore developing an automated image analysis pipeline that relies on latest technologies and techniques, such as 3D deconvolution and 3D particle tracking. This pipeline will be applied to study parameters, such as mitochondrial dynamics, which include for instance velocity, morphology, and spatial organization. [less ▲]

Eco-Systems Biology of Natural Lipid-Accumulating Microbial Communities

Poster (2011, September 27)

Biological wastewater treatment represents arguably the most widely used biotechnological process on Earth. Due to its high organic load, wastewater represents a potentially interesting energy commodity ... [more ▼]

Biological wastewater treatment represents arguably the most widely used biotechnological process on Earth. Due to its high organic load, wastewater represents a potentially interesting energy commodity that is currently not exploited comprehensively. Molecules of particular interest for sustainable bioenergy production are lipids which represent up to 45 % of the organic fraction of wastewater. Within biological wastewater treatment plants, specific lipid accumulating organism (LAO) communities exhibit specialized phenotypes that might be harnessed for the concomitant treatment of wastewater and the production of biodiesel (long chain fatty acid (LCFA) methyl esters). Furthermore, due to the unusual high-density enrichments in the LAO communities, these represent ideal models for the development of relevant high-resolution ecosystems biology methodologies. The main aims are: determining the exact genetic inventories required for excess lipid uptake, storage and processing within lipid accumulating bacterial populations ; determining the metabolic fate of organic molecules (lipids) within LAO communities ; and determining the functional organisation in relation to genetic heterogeneity of lipid accumulating bacterial populations. [less ▲]

Heterogenous Nucleation in Hard Spheres Systems

Poster (2011, August)

Indicators for the ex post detection of faking in survey data constructed from responses to the Big Five Inventory-10 (BFI-10)

Poster (2011, August)

Candidate mutations for early-onset lung cancer by family genome sequencing

Poster (2011, July)

Early-onset lung cancer has been studied as a rare, but distinct, sub-type of lung cancer. Genome-wide association studies (GWAS) have linked several genes with this form of malignancy. We sequenced the ... [more ▼]

Early-onset lung cancer has been studied as a rare, but distinct, sub-type of lung cancer. Genome-wide association studies (GWAS) have linked several genes with this form of malignancy. We sequenced the genomes of a family quartet in which one of the offspring was diagnosed with early-onset lung cancer at about 48 years of age. The family has a history of heavy smoking and the father had in the past been diagnosed with head and neck cancer. The DNA source was blood, which leads us to concentrate our analysis on Mendelian inheritance models. To make the inheritance pattern explicit, we establish the parental origin of the offspring’s genomes through phasing of their chromosomes. This helps identify whether mutations in the proband came from the father or the mother. More than 18 million sequence variants were initially identified in the proband through comparison to the hg19 reference genome. We reduce this list to fewer than 200 potentially functional variants (e.g. single nucleotide variations and short indels) present in the genomes of the proband and at least one parent, by applying a series of filters. We refine the list of candidate mutations further by comparison to gene candidates from GWAS studies and genes that are mutated in lung cancer tissue as recorded by The Cancer Genome Atlas. The results of our analysis are discussed and conclusions about possible causative mutations for early-onset lung cancer are drawn. [less ▲]

Chasing the flux: selecting target pathways through flux analysis of carbon metabolism

Poster (2011, June 26)

One of the goals of Systems Biology is to develop and utilise high-throughput methods for the measurement of parameters and concentrations on a genome-wide scale, while at the same time generating ... [more ▼]

One of the goals of Systems Biology is to develop and utilise high-throughput methods for the measurement of parameters and concentrations on a genome-wide scale, while at the same time generating predictive models for system behaviour. In studying genome-scale metabolic networks, the task of exhaustively assaying and measuring all reaction components can be daunting, because hundreds or even thousands of enzymes (activities and concentrations) need to be considered for the construction of a full-scale, detailed model. There is a clear need for strategies that allow us to systematically select the subsets of pathways and reactions which should be prioritized when studying metabolism. We present a methodology for selecting those reactions that carry the overwhelming majority of the carbon flux through the metabolic network. The recent community-driven reconstruction of the metabolic network of baker’s yeast [1] provides the basis for our analysis. Flux Balance Analysis provides a theoretical flux distribution. Results are constrained with GC-MS exometabolomic measurements of the carbon flux. Flux calculations can also be improved by using 13C measurements to determine intracellular metabolic fluxes. The solution of the constrained FBA problem gives us a ranked list of reactions, based on the amount of carbon flux through each reaction. We improve the specificity of the method further by performing an Elementary Flux Mode analysis, which provides us with target pathways consisting of the reactions that carry the most carbon flux. Our methodology allows us to cover more than 95% of the carbon flux by studying but a small subset of the reactions of the genome-scale metabolic network of baker’s yeast. [less ▲]

Structural properties of poly(N-isopropyl acrylamide)-based systems

Poster (2011, June 01)

O EFEITO DO NIVEL SOCIOECONÔMICO NO DESENVOLVIMENTO COGNITIVO INFANTIL

Poster (2011, May)

A inteligência humana pode ser dividida em dois tipos de inteligência: a cristalizada, a qual se baseia em habilidades adquiridas e aprendizado passado, e a fluida, que se refere à capacidade de ... [more ▼]

A inteligência humana pode ser dividida em dois tipos de inteligência: a cristalizada, a qual se baseia em habilidades adquiridas e aprendizado passado, e a fluida, que se refere à capacidade de relacionar idéias e de resolver novos problemas. Esse estudo explora os efeitos do nível socioeconômico (NSE) no desenvolvimento de habilidades cognitivas fluidas e cristalizadas em crianças. A pesquisa contou com um total de 105 participantes de 6 a 8 anos, pertencentes a três diferentes níveis socioeconômicos (alto, médio e baixo) de acordo com o Critério de Classificação Econômica Brasil (ABEP). Foram recrutadas crianças do primeiro e segundo ano do ensino fundamental de escolas particulares, de bairro e públicas em Salvador. Cada grupo continha 35 participantes equiparados em idade, sexo e ano de escolaridade. Os grupos não diferiram significativamente em aspectos nutricionais, estado emocional, peso ao nascer e tempo de gestação. As crianças foram avaliadas por uma extensa bateria de medidas comportamentais que exploraram a inteligência cristalizada (vocabulário, sintaxe e desempenho acadêmico) e a inteligência fluida (memória operacional e raciocínio indutivo). Os resultados apontaram que crianças inseridas em condições desprivilegiadas (baixo NSE) apresentaram desempenho significativamente pior nas medidas de inteligência cristalizada, quando comparadas às crianças que cresceram em ambiente mais favorável (alto NSE); com tamanho do efeito significativo. As crianças de baixo NSE apresentaram, também, um pior desempenho nos testes de inteligência fluida, que, embora significativo, foram menos expressivos que os efeitos correspondentes nas medidas de linguagem. Este estudo mostra que o crescimento em ambientes de baixo NSE constitui um sério fator de risco para o desenvolvimento cognitivo infantil. Sugere, ainda, que alguns sistemas neurocognitivos são mais sensíveis ao NSE que outros: o sistema de linguagem é fortemente impactado pelo NSE, enquanto a memória operacional e a resolução de conflitos são moderadamente influenciadas. Tais achados relacionados ao perfil neurocognitivo do NSE na infância são essenciais no sentido de testar hipóteses mais específicas sobre mecanismos causais e maximizar o efeito de intervenções. Deste modo, pais e escolas desempenham um papel fundamental em prover um ambiente cognitivo estimulante, a fim de otimizar o desenvolvimento intelectual infantil. [less ▲]

Contribution of Spatial Frequency and Orientation to upright and inverted face perception

Poster (2011, May)

It was recently shown that expert face perception relies on the extraction of horizontally oriented visual cues. Picture-plane inversion was found to eliminate horizontal, suggesting that this tuning ... [more ▼]

It was recently shown that expert face perception relies on the extraction of horizontally oriented visual cues. Picture-plane inversion was found to eliminate horizontal, suggesting that this tuning contributes to the specificity of face processing. The present experiments sought to determine the spatial frequency (SF) scales supporting the horizontal tuning of face perception. Participants were instructed to match upright and inverted faces that were filtered both in the frequency and orientation domains. Faces in a pair contained horizontal or vertical ranges of information in low, middle, or high SF (LSF, MSF, or HSF). Our findings confirm that upright (but not inverted) face perception is tuned to horizontal orientation. Horizontal tuning was the most robust in the MSF range, next in the HSF range, and absent in the LSF range. Moreover, face inversion selectively disrupted the ability to process horizontal information in MSF and HSF ranges. This finding was replicated even when task difficulty was equated across orientation and SF at upright orientation. Our findings suggest that upright face perception is tuned to horizontally oriented face information carried by intermediate and high SF bands. They further indicate that inversion alters the sampling of face information both in the orientation and SF domains. [less ▲]

Can you feel the game – How empathy in video games affects behavior

Poster (2011, May)

Shifts of spatial attention cued by irrelevant numbers: Electrophysiological evidence from a target discrimination task

Poster (2011, April)

Fischer et al. demonstrated that a centrally presented number can shift attention to the left/right when its magnitude is small/large. Two electrophysiological studies described these attentional effects ... [more ▼]

Fischer et al. demonstrated that a centrally presented number can shift attention to the left/right when its magnitude is small/large. Two electrophysiological studies described these attentional effects as event-related potentials (ERPs) at centro-parietal sites. Since both studies used target detection tasks, it remains currently unknown whether similar results would be obtained with a discrimination task. We used ERPs to test whether digit cues also induce attention shifts when participants perform a feature-discrimination task on targets. ERPs were recorded whereas subjects discriminated the colour of lateral targets that were preceded by a central non-predictive digit. Analysis of cue-locked controlateral vs. ipsilateral ERP activity showed the emergence of early preparatory attention-directing components in parietal and frontal regions. Moreover, target-locked P1 components at occipito-parietal sites were significantly modulated by digit magnitude-target side congruency. These results demonstrate that irrelevant digit cues also bias sensory processing when embedded in a feature-discrimination task. [less ▲]

When numbers act as attentional cues: behavioral and fMRI investigations

Poster (2011, February 11)

Establishing a Professional Development Network in England around Dynamic Mathematics Software

Poster (2011, February 10)

The principal aim of this project was to conduct research on GeoGebra-related professional development materials and approaches. The study was conducted through tight collaboration of educational ... [more ▼]

The principal aim of this project was to conduct research on GeoGebra-related professional development materials and approaches. The study was conducted through tight collaboration of educational researchers and mathematics teachers in England utilising frameworks of communities of inquiry (Jaworski, 2006) and collaborative design (Cobb, Confrey, diSessa, Lehrer, & Schauble, 2003). By joint collaboration and design we aimed to establish a core group of GeoGebra experts in England who can offer professional development and support for teachers. We also wanted to explore the ways in which GeoGebra can be used to enhance the teaching and learning of mathematics within the English curriculum. [less ▲]

Analysing Product Modelling Approaches Across Domains - Supporting Communication in Interdisciplinary Design Teams

Poster (2011)

An Action-Research project on the School/Family relationship in Luxembourg.

Poster (2011)

Facilitation and inhibition of return using numbers as attentional cues

Poster (2011)

Behavioural studies have shown a relation between numbers and space (DeHevia et al., 2008). Fischer and colleagues (2003) showed that digits can act as central spatial cues in a target detection task ... [more ▼]

Behavioural studies have shown a relation between numbers and space (DeHevia et al., 2008). Fischer and colleagues (2003) showed that digits can act as central spatial cues in a target detection task, resulting in shorter reaction times (RT) for left-sided targets when preceded by small numbers and for right-sided targets when preceded by large numbers. This facilitation effect indicates that numbers orient visuo-spatial attention to the left or right hemifield, depending on their magnitude. To date no studies investigated whether this facilitation is followed by inhibition of return at longer intervals, as could be expected with visuo-spatial attention shifts. To this aim, we designed an analogous paradigm to Fischer et al.’s, introducing additional longer intervals. Participants (n=25) were presented a task irrelevant digit (1,2 vs. 8,9) for 400ms and had to detect a brief (100ms) lateral target appearing after a variable interval (100, 250, 500, 750, 1000, 1250ms). A 2x6 repeated measures ANOVA of mean RT, with congruency and interval as within-subject variables yielded a significant interaction (F(5,24)=2.3, p<0.05). As expected, targets were detected faster when appearing in the congruent (small-left, large-right) hemifield after 250ms. Using the regression method proposed by Lorch and Myers (1990), the slope at this interval was significantly negative (t(24)=1.70, p=0.05); indicating a facilitation for the detection of targets in the congruent hemifield) (cf. Fischer et al., 2003). At the 1250ms interval, targets were detected significantly slower when they appeared in the congruent compared to the incongruent hemifield (yielding significantly positive slopes at 1250ms: t(24)=2.68, p=0.007). These findings provide the first evidence that digits not only produce facilitation effects at shorter intervals, but also induce inhibitory effects at longer intervals, confirming the visuo-spatial nature of the attention shifts associated with Arabic digits. [less ▲]

Eating Disorder Examination-Questionnaire: Prevalence of eating disturbances in the general population

Poster (2011)

Sciatic nerve constriction differentially alters pain-related behaviour and expresion of spianl cell markers in Lewis and Fischer rats

Poster (2011)

Developing number-space associations: SNARC effects in a color discrimination task in 11-year-olds

Poster (2011)

Behavioural studies show a relation between numbers and space in adults (DeHevia et al., 2008) and this association arises early in development (Opfer et al., 2010). The SNARC (Spatial Numerical ... [more ▼]

Behavioural studies show a relation between numbers and space in adults (DeHevia et al., 2008) and this association arises early in development (Opfer et al., 2010). The SNARC (Spatial Numerical Association of Response Codes) effect consists in faster reaction times (RTs) responding to small/large digits with the left/right hand respectively (Dehaene et al. 1993). It is thought to reflect the automaticity of the number-space link, since it arises not only during explicit magnitude judgment tasks, but also during magnitude-independent parity judgment tasks. Using a parity task Berch et al. (1999) found a SNARC effect in children of 9.2 years onwards, but not in younger children (7.8 years). One major issue raised was that parity judgments might be too difficult and therefore problematic to test young children (VanGalen&Reitsma, 2008). Hence, we designed a color judgment instead of a parity judgment task and tested 33 children from Grade 6 (mean age 11.4 years, SD 0.6). We also assessed number magnitude access using a magnitude judgment task. The results revealed a significantly negative slope in the color task [t(32)=2.47, p<0.01] and in the magnitude task [t(33)=1.75, p<0.05], reflecting a SNARC effect in both tasks (regression method by Lorch&Myers, 1990). A correlation analysis of the slopes of both tasks revealed a positive relationship (r=0.33, p<0.05) indicating that they partly measure the same processes. These results confirm the presence of robust SNARC effects in 6th-graders and indicate that they occur even using a simple color discrimination task that is strictly independent of semantic number processing. [less ▲]

Simulation Studies of Hard Sphere Suspensions Exposed to various Flow Dynamics

Poster (2011)

The influence of number sense acuity and mathematical expertise on mental addition strategies

Poster (2011)

Restrictive but family focused: Family climate affects parental mediation of children’s media use.

Poster (2011)

Zusammenhänge zwischen der subjektiven zirkadianen Phasenlage und psychischen Variablen.

Poster (2010, October)