References of "Article"
     in
Bookmark and Share    
Peer Reviewed
See detailFluctuations in GAD65 antibodies after clinical diagnosis of IDDM in young children
Batstra, M. R.; Pina, M.; Quan, J. et al

in Diabetes Care (1997), 20(4), 642-644

OBJECTIVE - To investigate whether the presence of GAD antibodies at onset of IDDM correlates to a more aggressive rate of β-cell destruction after clinical onset. RESEARCH DESIGN AND METHODS - We studied ... [more ▼]

OBJECTIVE - To investigate whether the presence of GAD antibodies at onset of IDDM correlates to a more aggressive rate of β-cell destruction after clinical onset. RESEARCH DESIGN AND METHODS - We studied GAD antibodies at onset of disease, after 1 year, and after 6 years in 33 consecutively referred children (mean age 8.08, range 1.7-16.3). In a subset of 11 patients, GAD antibodies were studied very frequently. The correlation between GAD antibodies and clinical parameters, including glycosylated hemoglobin, residual insulin secretion, and insulin dosage, was evaluated. RESULTS - GAD antibody titers were highly variable. Four patients became GAD antibody positive weeks to years after clinical onset. Other patients switched between testing positive and negative for GAD antibodies shortly after clinical onset. No correlation was found between the presence of GAD antibodies and the rate of β-cell destruction, but patients with high GAD antibody indexes at onset had significantly higher glycosylated hemoglobin levels. CONCLUSIONS - GAD antibodies at clinical onset do not predict the rate of β-cell destruction in young children with newly diagnosed IDDM. The highly variable GAD antibody levels suggest variation of the autoimmune process. [less ▲]

Detailed reference viewed: 105 (2 UL)
Full Text
Peer Reviewed
See detailWorld Wide Web caching: the application-level view of the Internet
Baentsch, Michael; Baum, Lothar; Molter, Georg et al

in IEEE Communications Magazine (1997), 35(6), 170-178

Detailed reference viewed: 116 (4 UL)
Peer Reviewed
See detailGeometry-dependent scattering through ballistic microstructures: Semiclassical theory beyond the stationary-phase approximation
Wirtz, Ludger UL; Tang, J. Z.; Burgdorfer, J.

in Physical Review. B (1997), 56(12), 7589-7597

The conductance of a ballistic microstructure shows strong fluctuations as a function of the Fermi wave number. We present a semiclassical-theory that describes these fluctuations in terms of bundles of ... [more ▼]

The conductance of a ballistic microstructure shows strong fluctuations as a function of the Fermi wave number. We present a semiclassical-theory that describes these fluctuations in terms of bundles of short trajectories. These trajectories provide the dominant contribution to electron transport through a weakly open microstructure. For the coupling between the quantum wires and the cavity, contributions beyond the stationary phase approximation are taken into account giving rise to diffraction effects. A comparison with full quantum calculations for st rectangular billiard is made. The peak positions of the power spectrum agree very well between the quantum and semiclassical theories. Numerical evidence is found for the breakdown of the semiclassical approximation for long paths. A simple explanation in terms of the dispersion of the semiclassical wave packet in the interior of the cavity is proposed. [less ▲]

Detailed reference viewed: 130 (4 UL)
See detailHierarchy of Norms in European Community Law
Hofmann, Herwig UL; Weiler, J. H. H.; Ballmann, Alexander et al

in Certain Rectangular Problems of European Integration (1997), II(Project IV/95/02),

Detailed reference viewed: 145 (9 UL)
Full Text
Peer Reviewed
See detailFiltrage de diffusions faiblement bruitées dans le cas corrélé
Schiltz, Jang UL

in Comptes Rendus de l'Académie des Sciences. Série I. Mathématique (1997), 325

Detailed reference viewed: 67 (2 UL)
Full Text
Peer Reviewed
See detailActions exponentielles et noyaux d'opérateurs
Molitor-Braun, Carine UL

in Travaux Mathématiques (1997), 9

Detailed reference viewed: 48 (1 UL)
Peer Reviewed
See detailMeasles virus transmission from infected to immune individuals - Implications for measles control and elimination
Vardas, E.; Andre, M.; Kreis, Stephanie UL et al

in South African Medical Journal (1997), 87(12), 1709

Detailed reference viewed: 92 (14 UL)
Full Text
Peer Reviewed
See detailCustomization of System Software for Large-scale Embedded Applications
Nehmer, Jürgen; Sturm, Peter; Baentsch, Michael et al

in Computer Communications (1997), 20

Detailed reference viewed: 95 (3 UL)
Peer Reviewed
See detailEtude de differentes methodes pour la mise en evidence des autoanticorps anti-glutamate-decarboxylase associes au developpement du diabete insulinodependant
Humbel, R. L.; Guillaume, A. C.; Schmit, P. et al

in Immuno-Analyse et Biologie Specialisee (1997), 12(5), 275-279

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react ... [more ▼]

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react predominantly with the native GAD. Various methods have been studied (radio immunoassay [RIA] and enzyme- linked immunosorbent assay [ELISA]). It was observed that at the present time only RIA-tests, in which GAD is presented in fluid phase, are able to detect antibodies. [less ▲]

Detailed reference viewed: 134 (0 UL)
Full Text
See detailProcessus de raisonnement et enseignement de l’algèbre au premier degré du secondaire
Vlassis, Joëlle UL; DEMONTY, I

in Informations Pédagogiques (1997), 38

Detailed reference viewed: 88 (1 UL)
Peer Reviewed
See detailRapid identification of measles virus strains by the heteroduplex mobility assay
Kreis, Stephanie UL; Whistler, T.

in Virus Research (1997), 47(2), 472197-203

The continued endemic presence of measles virus (MV), and the large number of isolates which are made in South Africa each year, demanded the use of a rapid and reliable pre-screening technique to select ... [more ▼]

The continued endemic presence of measles virus (MV), and the large number of isolates which are made in South Africa each year, demanded the use of a rapid and reliable pre-screening technique to select isolates for molecular epidemiological studies by sequence analysis. The heteroduplex mobility assay (HMA) was used to genetically characterize 47 MV isolates collected from three different provinces in South Africa, made between 1986 and 1995. The carboxyl-terminal 590 nt of the nucleocapsid (N) gene - the most variable region of the genome - was amplified by polymerase chain reaction (PCR) and subsequently subjected to HMA analysis for initial genotyping. The results showed three different patterns of heteroduplex formation by gel electrophoresis, representing two distinct wild-type lineages and one group of vaccine-like viruses. Comparison of HMA results with phylogenetic analysis of sequence data for several of the South African MV strains showed a complete correlation of results. The HMA proved to be a useful tool for screening MV isolates for use in molecular epidemiological studies. [less ▲]

Detailed reference viewed: 86 (19 UL)
Peer Reviewed
See detailEffects of an acute inflammation on the proportion of CGRP- and SP-containing joint afferents
Hanesch, Ulrike UL; Heppelmann, Bernd

in Neuroscience Letters (1997), 233

Detailed reference viewed: 22 (0 UL)
Full Text
Peer Reviewed
See detailSpace-charge controlled conduction in low-temperature-grown molecular-beam epitaxial GaAs,
Kordoš, P.; Marso, Michel UL; Förster, A. et al

in Applied Physics Letters (1997), 71

Current transport in low-temperature (LT) molecular-beam epitaxial GaAs grown at 200-300 °C on an n+ GaAs substrate is studied by means of current–voltage–temperature characteristics. The resistivity of ... [more ▼]

Current transport in low-temperature (LT) molecular-beam epitaxial GaAs grown at 200-300 °C on an n+ GaAs substrate is studied by means of current–voltage–temperature characteristics. The resistivity of LT GaAs at low electric fields is rho>108 Ohm cm, much higher than resulting from van der Pauw measurements. It is found that the measured resistivity decreases with increasing the LT GaAs thickness. This is explained by space-charge effect in the vicinity of n+/LT GaAs junction and subsequent suppression of hopping conduction in the high-field junction region. [less ▲]

Detailed reference viewed: 110 (0 UL)
See detailPestalozzi - fermerait-il nos écoles?
Tröhler, Daniel UL

in Bulletin du Centre de Documentation et de Recherche Pestalozzi (1997), 22

Detailed reference viewed: 43 (0 UL)
Full Text
Peer Reviewed
See detailCardiac myocytes and fibroblasts contain functional estrogen receptors.
Grohe, C.; Kahlert, S.; Lobbert, K. et al

in FEBS letters (1997), 416(1), 107-12

Gender-based differences found in cardiovascular diseases raise the possibility that estrogen may have direct effects on cardiac tissue. Therefore we investigated whether cardiac myocytes and fibroblasts ... [more ▼]

Gender-based differences found in cardiovascular diseases raise the possibility that estrogen may have direct effects on cardiac tissue. Therefore we investigated whether cardiac myocytes and fibroblasts express functional estrogen receptors. Immunofluorescence demonstrated estrogen receptor protein expression in both female and male rat cardiac myocytes and fibroblasts. Nuclear translocation of the estrogen receptor protein was observed after stimulation of cardiomyocytes with 17beta-estradiol (E2). Cells transfected with an estrogen-responsive reporter plasmid showed that treatment with E2 induced a significant increase in reporter activity. Furthermore, E2 induced a significant increase in expression of the estrogen receptors alpha and beta, progesterone receptor and connexin 43 in cardiac myocytes. Cardiac myocytes and fibroblasts contain functional estrogen receptors and estrogen regulates expression of specific cardiac genes. These data suggest that gender-based differences in cardiac diseases may in part be due to direct effects of estrogen on the heart. [less ▲]

Detailed reference viewed: 114 (0 UL)
Peer Reviewed
See detailAnalysis of Subspace System Identification Methods Based on Instrumental Variables and Subspace Fitting
Viberg, Mats; Wahlberg, Bo; Ottersten, Björn UL

in Automatica (1997), 33

Detailed reference viewed: 29 (0 UL)
Peer Reviewed
See detailAntagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation.
Neubuser, A.; Peters, H.; Balling, Rudi UL et al

in Cell (1997), 90(2), 247-55

Vertebrate organogenesis is initiated at sites that are often morphologically indistinguishable from the surrounding region. Here we have identified Pax9 as a marker for prospective tooth mesenchyme prior ... [more ▼]

Vertebrate organogenesis is initiated at sites that are often morphologically indistinguishable from the surrounding region. Here we have identified Pax9 as a marker for prospective tooth mesenchyme prior to the first morphological manifestation of odontogenesis. We provide evidence that the sites of Pax9 expression in the mandibular arch are positioned by the combined activity of two signals, one (FGF8) that induces Pax9 expression and the other (BMP2 and BMP4) that prevents this induction. Thus it appears that the position of the teeth is determined by a combination of two different types of signaling molecules produced in wide but overlapping domains rather than by a single localized inducer. We suggest that a similar mechanism may be used for specifying the sites of development of other organs. [less ▲]

Detailed reference viewed: 111 (0 UL)
Peer Reviewed
See detailOnmogelijke opvoeding. Kanttekeningen bij de pedagogische overdrachtsmetafoor.
Biesta, Gert UL

in Comenius (1997), 17(4), 312-324

Detailed reference viewed: 60 (0 UL)
Full Text
Peer Reviewed
See detailColor-Sensistive Si-Photodiode Using Porous Silicon Interference Filters
Krüger, M.; Berger, M. G.; Marso, Michel UL et al

in Japanese Journal of Applied Physics (1997), 36(1997), 24-26

Detailed reference viewed: 24 (0 UL)
Peer Reviewed
See detail« Pierre Klossowski: voyeurisme en theofanie»
Roelens, Nathalie UL

in ALW-Cahier (1997)

Detailed reference viewed: 81 (6 UL)
Full Text
Peer Reviewed
See detailCapacity Utilization and Market Power
Fagnart, J.F.; Licandro, O.; Sneessens, Henri UL

in Journal of Economic Dynamics and Control (1997), 22

We propose a theoretical macroeconomic model where capacity underutilization follows from idiosyncratic demand uncertainty at the time monopolistic firms must choose their productive capacity. After their ... [more ▼]

We propose a theoretical macroeconomic model where capacity underutilization follows from idiosyncratic demand uncertainty at the time monopolistic firms must choose their productive capacity. After their investment decision, firms facing a low demand will typically prefer to run excess capacities rather than reduce their profit margin; firms at full capacity will respond to demand fluctuations solely by price adjustments. We show that the proportion of firms with idle capacities influences crucially the short-run response of the economy to exogenous disturbances and, in particular, the relative importance of price and quantity adjustments. [less ▲]

Detailed reference viewed: 126 (2 UL)
Full Text
Peer Reviewed
See detailColor-Sensitive Photodetector Based on Porous Silicon Superlattices
Krüger, M.; Marso, Michel UL; Berger, M. G. et al

in Thin Solid Films (1997), 297(1997), 241-244

Detailed reference viewed: 89 (0 UL)
Full Text
Peer Reviewed
See detailElectrical Behaviour of the InP/InGaAs Based MSM-2DEG Diode
Marso, Michel UL; Horstmann, M.; Hardtdegen, H. et al

in Solid-State Electronics (1997), 41(1997), 25-31

Detailed reference viewed: 39 (0 UL)
Peer Reviewed
See detailThe HSSP database of protein structure-sequence alignments
Schneider, Reinhard UL; deDaruvar, A.; Sander, C.

in Nucleic Acids Research (1997), 25(1), 226-230

HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment ... [more ▼]

HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment of all available homologues and a sequence profile characteristic of the family. The list of homologues is the result of a database search in SwissProt using a position-weighted dynamic programming method for sequence profile alignment (MaxHom). The database is updated frequently. The listed homologues are very likely to have the same 3-D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of aligned sequence families, but also a database of implied secondary and tertiary structures covering 29% of all SwissProt-stored sequences. [less ▲]

Detailed reference viewed: 123 (0 UL)
Peer Reviewed
See detailMethodische Bemerkungen zu Kontextualisierung und Wirkungsgeschichte in der pädagogischen Historiographie
Tröhler, Daniel UL

in Neue Pestalozzi-Blätter (1997), 3(2), 28-29

Detailed reference viewed: 42 (1 UL)
Peer Reviewed
See detailSegment-specific expression of the gap junction gene connexin 31 during hindbrain development
Dahl, E; Willecke, K; Balling, Rudi UL

in Development Genes & Evolution (1997), (207), 359-361

Detailed reference viewed: 113 (0 UL)
Full Text
Peer Reviewed
See detailPain, Anxiety, and Cooperativeness in Children with Cerebral Palsy after Rhizotomy: Changes Throughout Rehabilitation
Miller, A. Cate; Johann-Murphy, Marjorie; Pit-Ten Cate, Ineke UL

in Journal of Pediatric Psychology (1997), 22(5), 689-705

Assessed pain, anxiety, physical functioning, and cooperativeness in 32 children with spastic cerebral palsy. This is the first study to assess children throughout rehabilitation following selective ... [more ▼]

Assessed pain, anxiety, physical functioning, and cooperativeness in 32 children with spastic cerebral palsy. This is the first study to assess children throughout rehabilitation following selective posterior rhizotomy. Results of the Observational Scale of Behavioral Distress and observer Liken ratings confirmed the hypothesis that children's pain and anxiety decrease over time. Children's physical functioning and cooperativeness improve over time. No significant correlation was found between pain and changes in physical functioning. Cognitive impairment, parental involvement, and children's pain behaviors explained 77% and 56% of the variance in two forms of cooperativeness. Research and clinical implications are discussed, and special considerations regarding pain assessment and management in this population are addressed. [less ▲]

Detailed reference viewed: 135 (0 UL)
See detailDe toekomst van de historische pedagogiek.
Selten, P. J. H.; Bakker, P. C. M.; Biesta, Gert UL

in Comenius (1997), 17(3), 195-199

Detailed reference viewed: 60 (0 UL)
See detailPedestrian guide to analyzing sequence databases
Rost, B.; Schneider, Reinhard UL; Sander, C.

in WWW-publication (1997)

Over the past few years our means of communication have changed rapidly due to the growth of the World Wide Web (WWW). The Web enables molecular biologists to immediately access databases, scan literature ... [more ▼]

Over the past few years our means of communication have changed rapidly due to the growth of the World Wide Web (WWW). The Web enables molecular biologists to immediately access databases, scan literature, find information about related research and researchers, and to trace cell cultures. Wet-lab biologists can uncover information about the protein of interest without having to become experts in sequence analysis. Here, we present a variety of tools; provide an overview of the state-of-the art in sequence analysis; and described some of the principles of the methods. [less ▲]

Detailed reference viewed: 69 (2 UL)
See detailSaar-Lor-Lux - Die Bedeutung der lokalen grenzüberschreitenden Kooperation für den europäischen Integrationsprozeß.
Schulz, Christian UL; Brücher, Wolfgang

in Magazin Forschung (1997), (1), 46-53

Detailed reference viewed: 89 (1 UL)
Peer Reviewed
See detailA single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
Behrmann, Iris UL; Janzen, C.; Gerhartz, C. et al

in Journal of Biological Chemistry (1997), 272(8), 5269-74

We established a system of receptor chimeras that enabled us to induce heterodimerization of different cytoplasmic tails. Fusion constructs were created that are composed of the extracellular parts of the ... [more ▼]

We established a system of receptor chimeras that enabled us to induce heterodimerization of different cytoplasmic tails. Fusion constructs were created that are composed of the extracellular parts of the interleukin-5 receptor alpha and beta chains, respectively, and the transmembrane and intracellular parts of gp130, the signal transducing chain of the interleukin-6 receptor complex. In COS-7 transfectants we observed a dose-dependent interleukin-5-inducible STAT1 activation for which the presence of both the alpha and the beta chain chimera was needed. No STAT activity was detected if one of the cytoplasmic tails of the receptor complex was deleted, indicating that STAT activity resulted from a receptor dimer rather than from higher receptor aggregates. We further investigated whether dimerization of STAT1 depends on the juxtaposition of two STAT recruitment modules in a receptor complex. We show that a receptor dimer with only a single STAT1 docking site was still able to lead to STAT1 activation. This indicates that the formation of a paired set of STAT binding sites in a receptor complex is not the prerequisite for STAT factor dimerization. Our findings are discussed in view of alternative STAT dimerization models. [less ▲]

Detailed reference viewed: 103 (0 UL)
Full Text
Peer Reviewed
See detailEffects of estrogen on skeletal myoblast growth.
Kahlert, S.; Grohe, C.; Karas, R. H. et al

in Biochemical and biophysical research communications (1997), 232(2), 373-8

To determine the role of estrogen in skeletal muscle growth, we investigated estrogen receptor-mediated effects on proliferation in skeletal myoblasts. In L6, C2C12 and Sol8 myoblasts estrogen receptor ... [more ▼]

To determine the role of estrogen in skeletal muscle growth, we investigated estrogen receptor-mediated effects on proliferation in skeletal myoblasts. In L6, C2C12 and Sol8 myoblasts estrogen receptor was demonstrated by immunoblotting, immunofluorescence microscopy and transfection studies. Estrone induced a significant increase in myoblast growth whereas 17 beta-estradiol had no effect. Furthermore in L6-cells estrone (c-fos: 3.9-fold, egr-1: 4.6-fold) induced immediate-early gene induction significantly stronger than 17 beta-estradiol (c-fos: 1.7-fold, egr-1: 2.3-fold; p < 0.05). Skeletal myoblasts express functional estrogen receptors. Estrogens differ in the activation of skeletal myoblast growth and immediate-early gene induction. [less ▲]

Detailed reference viewed: 138 (0 UL)
Peer Reviewed
See detailMythos Menalk? Neue Fragen zu Pestalozzis Jugend
Tröhler, Daniel UL

in Neue Pestalozzi-Blätter (1997), 3(2), 24-27

Detailed reference viewed: 63 (1 UL)
Peer Reviewed
See detailStructural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes.
Golsteyn, R. M.; Beckerle, M. C.; Koay, T. et al

in Journal of cell science (1997), 110 ( Pt 16)

The intracellular bacterial parasite Listeria monocytogenes produces ActA protein at its surface to facilitate the localized assembly of actin-filled comets that are required for movement. The ... [more ▼]

The intracellular bacterial parasite Listeria monocytogenes produces ActA protein at its surface to facilitate the localized assembly of actin-filled comets that are required for movement. The organization of actin in Listeria comets shows striking similarity to the organization of actin at the plasma membrane of mammalian cells. Therefore we examined the possibility that an ActA-like protein is present in mammalian cells. By using antibodies directed against ActA, we identified zyxin as an ActA related protein in a number of cell types. We compared the functions of ActA and zyxin by transient expression of variants tagged with an inner plasma membrane localization sequence (a CAAX box). Targeting of the proline rich domain of zyxin to the plasma membrane disrupts the actin cytoskeleton and cell shape in a manner similar to that which occurs with membrane-targeted ActA sequences. A chimeric protein composed of the N-terminal domain of ActA fused to the N-terminal and central domains of zyxin induced a full ActA response in cells. Furthermore, zyxin and ActA exhibit common protein partners in vitro. On the basis of the shared properties of zyxin and ActA, we propose that zyxin enhances actin organizing activity in mammalian cells. [less ▲]

Detailed reference viewed: 51 (0 UL)
Full Text
Peer Reviewed
See detailRevêtements de courbes elliptiques à multiplication complexe par des courbes hyperelliptiques et sommes de caractères
Leprévost, Franck UL; Morain, François

in Journal of Number Theory (1997), 64(2), 165-182

Detailed reference viewed: 93 (0 UL)
Full Text
Peer Reviewed
See detailSur certains sous-groupes de torsion de Jacobiennes de courbes hyperelliptiques de genre g > 0
Leprévost, Franck UL

in Manuscripta Mathematica (1997), 92(I), 47-63

Detailed reference viewed: 107 (0 UL)
Full Text
Peer Reviewed
See detailEnhancing the Web's infrastructure: from caching to replication
Baentsch, Michael; Baum, Lothar; Molter, Georg et al

in IEEE Internet Computing (1997), 1(2), 18-27

Detailed reference viewed: 102 (1 UL)
Full Text
Peer Reviewed
See detailUne caractérisation différentielle des points de Weierstrass généralisés d'une surface de Riemann compacte de genre g > 1
Leprévost, Franck UL

in Journal de Mathématiques Pures et Appliquées (1997), 76

Detailed reference viewed: 97 (0 UL)
See detailRetrospektive Bewertungen des eigenen Lebens: LZG – Lebenszufriedenheits-Graph.
Ferring, Dieter UL; Filipp, Sigrun-Heide

in Zeitschrift für Entwicklungspsychologie und Padagogische Psychologie (1997), 29(1)

Detailed reference viewed: 84 (0 UL)
Peer Reviewed
See detailHuman umbilical cord blood-derived eosinophils cultured in the presence of IL-3 and IL-5 respond to fMLP with [Ca2+]i variation and O2- production
Zardini, D. M.; Heuschling, Paul UL; Gallois, A. et al

in Journal of Immunological Methods (1997), 205(1), 1-9

In the presence of interleukin-3 and interleukin-5, eosinophil precursors from human umbilical cord blood mononuclear cells were regularly differentiated into mature eosinophil-like cells expressing ... [more ▼]

In the presence of interleukin-3 and interleukin-5, eosinophil precursors from human umbilical cord blood mononuclear cells were regularly differentiated into mature eosinophil-like cells expressing normal morphology and cyanide-resistant peroxidase. O2- production and [Ca2+]i rise were measured in these in vitro differentiated eosinophils after fMLP stimulation; with dihydrorhodamine-123 and fura-2, respectively. Umbilical cord blood-derived eosinophils responded to fMLP (0.01 nM to 3 microM) with a concentration-dependent production of O2- (EC50 = 63.1 +/- 17.2 nM; Emax = 71.0 +/- 6.2 pmol/min/10(6) cells). O2- production was correlated with an fMLP concentration-dependent increase in [Ca2+]i (EC50 = 32.5 +/- 14.9 nM; Emax = 200.0 +/- 23.9 nM). These results indicate that human umbilical cord blood-derived eosinophils demonstrate functional characteristics similar to adult human peripheral blood eosinophils after activation by fMLP. Therefore, the large numbers of eosinophils (2-3 x 10(6)/ml cord blood) which can be obtained by culture of human cord blood mononuclear cells may serve as a useful model for future studies which will provide insight into the pathogenesis of diseases associated with eosinophils. [less ▲]

Detailed reference viewed: 153 (1 UL)
Full Text
Peer Reviewed
See detailAnger suppression, reactivity and hypertension risk: Gender makes a difference
Vögele, Claus UL; Cheeseman, Karen; Jarvis, Ann

in Annals of Behavioral Medicine : A Publication of the Society of Behavioral Medicine (1997), 19

The present study investigated gender-related differences in cardiovascular reactivity and the role of anger inhibition and risk for future hypertension. Tonic blood pressure served as an index of ... [more ▼]

The present study investigated gender-related differences in cardiovascular reactivity and the role of anger inhibition and risk for future hypertension. Tonic blood pressure served as an index of hypertension risk. Twenty-eight female and 26 male college students with high and low normal blood pressure were recruited on the basis of their mean arterial pressure. Continuous measures of heart rate and blood pressure were taken while participants carried out a series of behavioral manoeuvres including mental arithmetic, interpersonal challenge, a frustrating psychomotor test, and the cold pressor test. Participants also completed inventories assessing trait anxiety, trait anger, anger expression, and Type A. The results are in concordance with previous findings and show higher cardiovascular reactivity in men than in women and in subjects at risk for hypertension. Within the male group, a combination of hypertension risk and anger suppression led to the highest reactivity, whereas in female subjects, differences in anger-in had no effect on reactivity. The implications of these results are discussed in light of sex differences in cardiovascular morbidity and mortality. [less ▲]

Detailed reference viewed: 140 (0 UL)
Peer Reviewed
See detailMaximum Likelihood Array Processing in Spatially Correlated Noise Fields Using Parametrized Signals
Viberg, Mats; Stoica, Petre; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (1997), 45(4), 9961004

Detailed reference viewed: 28 (0 UL)
Peer Reviewed
See detailCalcitonin gene-related peptide- and substance P-like immunoreactive fibers in the spermatic nerve and testis of the dog.
Tamura, Ryoko; Hanesch, Ulrike UL; Schmidt, Robert et al

in Neuroscience Letters (1997), 235

Detailed reference viewed: 91 (1 UL)
Peer Reviewed
See detailQuantitative examination of calcitonin gene-related peptide immunoreactive nerve fibers in the cat knee joint capsule
Heppelmann, Bernd; Shahbazian, Zarah; Hanesch, Ulrike UL

in Anatomy & Embryology (1997), 195

Detailed reference viewed: 36 (0 UL)
Full Text
Peer Reviewed
See detailSurface-induced organization of linear molecules on nanostructured polytetrafluoroethylene: Crystalline state of poly[vinylidenefluoride-trifluoroethylene].
Krüger, Jan-Kristian UL; Heydt, B.; Fischer, C. et al

in Physical Review. B, Condensed Matter and Materials Physics (1997), 55(6), 3497-3506

Highly crystalline and uniaxial-oriented polytetrafluoroethylene films, nanostructured in one dimension, were used to produce a fully crystalline, thermoreversible morphology in the ferroelectric ... [more ▼]

Highly crystalline and uniaxial-oriented polytetrafluoroethylene films, nanostructured in one dimension, were used to produce a fully crystalline, thermoreversible morphology in the ferroelectric copolymer poly[vinylidenefluoride-trifluoroethylene]. The resulting state is built up of regularly stacked lamellar crystals of about 100 nm thickness and lateral dimensions of about 6 μm. [less ▲]

Detailed reference viewed: 116 (1 UL)
Full Text
Peer Reviewed
See detailSuperheavy nuclei in selfconsistent nuclear calculations
Rutz, K.; Bender, M.; Bürvenich, T. et al

in Physical Review. C, Nuclear Physics (1997), 56(1), 238-243

The shell structure of superheavy nuclei is investigated within various parametrizations of relativistic and nonrelativistic nuclear mean-field models. The heaviest known even-even nucleus 156 264Hs108 is ... [more ▼]

The shell structure of superheavy nuclei is investigated within various parametrizations of relativistic and nonrelativistic nuclear mean-field models. The heaviest known even-even nucleus 156 264Hs108 is used as a benchmark to estimate the predictive value of the models. From that starting point, doubly magic spherical nuclei are searched in the region Z51102140 and N5134–298. They are found at (Z5114 , N5184), (Z5120 , N5172), or at (Z5126 , N5184), depending on the parametrization. [less ▲]

Detailed reference viewed: 170 (3 UL)
See detailSubjektives Wohlbefinden im Alter: Struktur- und Stabilitätsanalysen.
Ferring, Dieter UL; Filipp, Sigrun-Heide

in Psychologische Beiträge (1997), 39(3)

Detailed reference viewed: 101 (1 UL)
Full Text
Peer Reviewed
See detail0.1 µm T-gate Al-free InP/InGaAs/InP pHEMTs for W-Band Applications Using a Nitrogen Carrier for LP-MOCVD Growth
Schimpf, K.; Sommer, M.; Horstmann, M. et al

in IEEE Electron Device Letters (1997), 18

We report on the dc and RF performance of HEMT’s based on the Al-free material system InP/InGaAs/InP. These structures were grown by LP-MOCVD using a nitrogen carrier. The influence of gate length and ... [more ▼]

We report on the dc and RF performance of HEMT’s based on the Al-free material system InP/InGaAs/InP. These structures were grown by LP-MOCVD using a nitrogen carrier. The influence of gate length and channel composition on the performance of these devices is investigated.We demonstrate that optimum dc and RF performance using highly strained channels can be obtained only if additional composite channels are grown. The cutoff frequencies fT =160 GHz and fmax=260 GHz for a 0.1- um T-gate device indicate the suitability of our devices for W-Band applications. [less ▲]

Detailed reference viewed: 1377 (44 UL)
See detailTraditionsbewusstsein - eine wenig beachtete Grundhaltung
Tröhler, Daniel UL

in Infos und Akzente (1997), (17), 11-14

Detailed reference viewed: 95 (0 UL)
Peer Reviewed
See detailQuantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs.
Filser, N.; Margue, Christiane UL; Richter, C.

in Biochemical and biophysical research communications (1997), 233(1), 102-7

Oxidative damage to mitochondrial DNA (mtDNA) is considered a major contributor in aging. An age-dependent increase of oxidative damage and of the quantity of partially deleted mtDNA was reported for ... [more ▼]

Oxidative damage to mitochondrial DNA (mtDNA) is considered a major contributor in aging. An age-dependent increase of oxidative damage and of the quantity of partially deleted mtDNA was reported for several rat and human organs. Here, a systematic investigation of ten different tissues and organs of 20-months-old rats was performed. The amount of mtDNA and age-dependent 4.8 kb deletion (delta mtDNA4834) was determined by competitive polymerase chain reaction, along with the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSHPx). The data were related to the corresponding metabolic rates. MtDNA content was highest in heart and lowest in spleen. delta mtDNA4834 was detected in all ten tissues and organs, and its amount was highest in liver and lowest in intestine. In heart, lung, muscle, and bone-marrow the deletion could not be quantified because of a point mutation, an A-->T transition at position 8107. Activities of SOD and GSHPx were highest in liver and lowest in intestinal mucosa. A negative correlation between mtDNA content and delta mtDNA4834, and a positive correlation between metabolic rate, GSHPx, and the deletion was found. These results suggest that the occurrence of delta mtDNA4834 in rat is related to oxidative stress. [less ▲]

Detailed reference viewed: 99 (1 UL)
Full Text
See detailThe nature of the starter unit for the rapamycin polyketide synthase
König, Ariane UL; Schwecke, T.; Molnár, I. et al

in Angewandte Chemie International Edition (1996), 35(19), 2249-2251

A remarkably high level of incorporation is observed when 2,2,5,5-tetradeutero -3,4- dihydroxycyclo -hexanecarboxylic acid is fed to the rapamycin-producing organism. Intriguingly, however, analysis of ... [more ▼]

A remarkably high level of incorporation is observed when 2,2,5,5-tetradeutero -3,4- dihydroxycyclo -hexanecarboxylic acid is fed to the rapamycin-producing organism. Intriguingly, however, analysis of the gene sequence for the rapamycin polyketide synthase has suggested that the free acid may not normally be involved in rapamycin biosynthesis. [less ▲]

Detailed reference viewed: 132 (4 UL)
Full Text
Peer Reviewed
See detailOrganisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase
Aparicio, J. F.; Molnar, I.; Schwecke, T. et al

in Gene (1996), 169(1), 9-16

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme ... [more ▼]

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme activities, each module catalysing a specific round of polyketide chain extension. Detailed sequence comparison between these protein modules has allowed further characterisation of aa that may be important in catalysis or specificity. The acyl-carrier protein (ACP), beta-ketoacyl-ACP synthase (KS) and acyltransferase (AT) domains (the core domains) have an extremely high degree of mutual sequence homology. The KS domains in particular are almost perfect repeats over their entire length. Module 14 shows the least homology and is unique in possessing only core domains. The enoyl reductase (ER), beta-ketoacyl-ACP reductase (KR) and dehydratase (DH) domains are present even in certain modules where they are not apparently required. Four DH domains can be recognised as inactive by characteristic deletions in active site sequences, but for two others, and for KR and ER in module 3, the sequence is not distinguishable from that of active counterparts in other modules. The N terminus of RAPS1 contains a novel coenzyme A ligase (CL) domain that activates and attaches the shikimate-derived starter unit, and an ER activity that may modify the starter unit after attachment. The sequence comparison has revealed the surprisingly high sequence similarity between inter-domain 'linker' regions, and also a potential amphipathic helix at the N terminus of each multienzyme subunit which may promote dimerisation into active species. [less ▲]

Detailed reference viewed: 96 (2 UL)
Full Text
Peer Reviewed
See detailOrganisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the genes flanking the polyketide synthase
Aparicio, J. F.; Molnár, I.; Schwecke, T. et al

in Gene (1996), 169(1), 1-7

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme ... [more ▼]

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme activities, each module catalysing a specific round of polyketide chain extension. Detailed sequence comparison between these protein modules has allowed further characterisation of aa that may be important in catalysis or specificity. The acyl-carrier protein (ACP), beta-ketoacyl-ACP synthase (KS) and acyltransferase (AT) domains (the core domains) have an extremely high degree of mutual sequence homology. The KS domains in particular are almost perfect repeats over their entire length. Module 14 shows the least homology and is unique in possessing only core domains. The enoyl reductase (ER), beta-ketoacyl-ACP reductase (KR) and dehydratase (DH) domains are present even in certain modules where they are not apparently required. Four DH domains can be recognised as inactive by characteristic deletions in active site sequences, but for two others, and for KR and ER in module 3, the sequence is not distinguishable from that of active counterparts in other modules. The N terminus of RAPS1 contains a novel coenzyme A ligase (CL) domain that activates and attaches the shikimate-derived starter unit, and an ER activity that may modify the starter unit after attachment. The sequence comparison has revealed the surprisingly high sequence similarity between inter-domain 'linker' regions, and also a potential amphipathic helix at the N terminus of each multienzyme subunit which may promote dimerisation into active species. [less ▲]

Detailed reference viewed: 163 (2 UL)
See detailWerteerziehung und pluralistische Gesellschaft
Tröhler, Daniel UL

in Aktuell (1996), (4), 7-10

Detailed reference viewed: 54 (0 UL)
Full Text
Peer Reviewed
See detailSur une conjecture sur les points de torsion rationnels des Jacobiennes de courbes
Leprévost, Franck UL

in Journal für die Reine und Angewandte Mathematik (1996), 473

Detailed reference viewed: 118 (0 UL)
Peer Reviewed
See detail[Beta blockers in chronic heart failure. Clinical position on the topic].
Dominiak, P.; Erdmann, E.; Kreuzer, H. et al

in Der Internist (1996), 37(12), 1274-81279

Detailed reference viewed: 67 (0 UL)
Peer Reviewed
See detailEstimation of Nominal Direction of Arrival and Angular Spread Using an Array of Sensors
Trump, T.; Ottersten, Björn UL

in Signal Processing (1996), 50(1-2), 5769

Detailed reference viewed: 46 (0 UL)
Peer Reviewed
See detailEndothelin-1 does not modulate O2.release and [Ca(2+)]i variations in resting or differentiated HL-60 cells
Gallois, A.; Bueb, Jean-Luc UL; Tschirhart, Eric UL

in Fundamental and Clinical Pharmacology (1996), 10(1), 28-32

Endothelin-1 (ET-1) by itself was not an effective stimulus for inducing superoxide (O2.) generation in human resting or DMSO-differentiated neutrophil-like HL-60 cells. ET-1 (0.01-100 nM) was not able to ... [more ▼]

Endothelin-1 (ET-1) by itself was not an effective stimulus for inducing superoxide (O2.) generation in human resting or DMSO-differentiated neutrophil-like HL-60 cells. ET-1 (0.01-100 nM) was not able to modulate O2. generation stimulated by the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP, EC50 = 4.24 +/- 1.63 nM in the absence and 3.16 +/- 1.95 nM in the presence of ET-1). Neither did ET-1 (0.01-100 nM) promote the mobilization of intracellular calcium ions or modulate fMLP-induced [Ca(2+)]i increase in this model of human neutrophils. Phosphoramidon, a neutral endopeptidase inhibitor, was not able to reveal any biological (O2.) or biochemical ([Ca(2+)]i response to ET-1 in the absence or in the presence of fMLP in these cells. These results indicate that DMSO-differentiated neutrophil-like HL-60 cells are not sensitive to ET-1 in terms of O2. generation or [Ca(2+)]i variations. [less ▲]

Detailed reference viewed: 110 (2 UL)
Peer Reviewed
See detailL’avis 1/94 de la C.J.C.E. et ses implications sur l’ordre juridique communautaire
Neframi, Eleftheria UL

in Revue hellénique de droit européen (1996)

Detailed reference viewed: 167 (5 UL)
Full Text
Peer Reviewed
See detailInternal Finance and Capital Accumulation in a Dynamic General Equilibrium Model with Credit Constraints
Sneessens, Henri UL; Stefani, Maria Lucia

in Louvain Economic Review - Recherches Economiques de Louvain (1996), 62(2-3), 255-86

Detailed reference viewed: 40 (1 UL)
Peer Reviewed
See detailPropagation Delay Estimation in Asynchronous Direct-Sequence Code-Division Multiple Access Systems
Ström, Erik G.; Parkvall, Stefan; Miller, Scott L. et al

in IEEE Transactions on Communications (1996), 44(1), 8493

Detailed reference viewed: 37 (0 UL)
Peer Reviewed
See detail«De la colère de l'escargot à la rage de l'expression»
Roelens, Nathalie UL

in C.R.I.N. (1996)

Detailed reference viewed: 89 (1 UL)
Peer Reviewed
See detailInterkultureller Fremdsprachenunterricht und die Heterogenität von Kulturen
Hu, Adelheid UL

in Zeitschrift für Interkulturellen Fremdsprachenunterricht (1996), 1(3), 16

Detailed reference viewed: 189 (1 UL)
Peer Reviewed
See detail«Egotisme et autodérision chez Stendhal. Je tombe donc je suis»
Roelens, Nathalie UL

in Dix-neuf/Vingt, Revue de littérature moderne (1996)

Detailed reference viewed: 79 (1 UL)
Peer Reviewed
See detailA reading of Troubadour insult songs: the Comunals cycle
Leglu, Catherine UL

in Reading Medieval Studies (1996), XXII

An analysis of a cycle of aggressive songs by troubadours.

Detailed reference viewed: 76 (1 UL)
Peer Reviewed
See detailPolizei und Fremde. Spezifische Belastungssituationen und die Genese von Feindbildern und Übergriffen
Willems, Helmut UL; Eckert, Roland; Jungbauer, Johannes

in Neue Kriminalpolitik (1996), 8. Jg(Heft 4), 28-32

Detailed reference viewed: 145 (0 UL)
Full Text
Peer Reviewed
See detail16 GHz Bandwidth MSM Photodetector and 45/85 GHz fT/fmax HEMT Prepared on an Identical InGaAs/InP Layer Structure
Horstmann, M.; Schimpf, K.; Marso, Michel UL et al

in Electronics Letters (1996), 32

Detailed reference viewed: 163 (0 UL)
See detailJugend und Politik: Politisches Interesse, Institutionenvertrauen, Wertorientierungen und Partizipationsbereitschaften
Willems, Helmut UL; Gille, Martina; Krüger, Winfried et al

in DISKURS : Studien zu Kindheit, Jugend, Familie und Gesellschaft (1996), 6(1), 62-70

Detailed reference viewed: 98 (1 UL)
Peer Reviewed
See detailMaximum Likelihood Array Processing for Stochastic Coherent Sources
Stoica, Petre; Ottersten, Björn UL; Viberg, Mats et al

in IEEE Transactions on Signal Processing (1996), 44

Detailed reference viewed: 42 (0 UL)
Full Text
Peer Reviewed
See detailBioinformatics and the discovery of gene function
Casari, G.; Daruvar, Dea; Sander, C. et al

in Trends in Genetics (1996), 128(7), 244-245

Scientific history was made in completing the yeast genuine sequence, yet its 13 Mb are a mere starting point. Two challenges loom large: to decipher the function of all genes and to describe the workings ... [more ▼]

Scientific history was made in completing the yeast genuine sequence, yet its 13 Mb are a mere starting point. Two challenges loom large: to decipher the function of all genes and to describe the workings of the eukaryotic cell in full molecular detail. A combination of experimental and theoretical approaches will be brought to bear on these challenges. What will be next in yeast genome analysis from the point of view of bioinformatics? [less ▲]

Detailed reference viewed: 159 (0 UL)
Full Text
Peer Reviewed
See detailDer Einfluss der Motivation auf das Gedächtnis über Personen und die Eindrucksbildung
Krolak-Schwerdt, Sabine UL

in Zeitschrift für experimentelle Psychologie (1996), 43

Detailed reference viewed: 251 (1 UL)
Peer Reviewed
See detailL’évolution du monde syndical luxembourgeois dans l’entre-deux-guerres
Scuto, Denis UL

in Hemecht : Zeitschrift für Luxemburger Geschichte = Revue d'Histoire Luxembourgeoise (1996)

Detailed reference viewed: 60 (0 UL)
Peer Reviewed
See detailThe Evil of Superefficiency
Stoica, Petre; Ottersten, Björn UL

in Signal Processing (1996), 55(1), 133136

Detailed reference viewed: 29 (0 UL)
Peer Reviewed
See detailPax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
Wallin, J.; Eibel, H.; Neubuser, A. et al

in Development (1996), 122(1), 23-30

Pax1 is a transcriptional regulatory protein expressed during mouse embryogenesis and has been shown to have an important function in vertebral column development. Expression of Pax1 mRNA in the embryonic ... [more ▼]

Pax1 is a transcriptional regulatory protein expressed during mouse embryogenesis and has been shown to have an important function in vertebral column development. Expression of Pax1 mRNA in the embryonic thymus has been reported previously. Here we show that Pax1 protein expression in thymic epithelial cells can be detected throughout thymic development and in the adult. Expression starts in the early endodermal epithelium lining the foregut region and includes the epithelium of the third pharyngeal pouch, a structure giving rise to part of the thymus epithelium. In early stages of thymus development a large proportion of thymus cells expresses Pax1. With increasing age, the proportion of Pax1-expressing cells is reduced and in the adult mouse only a small fraction of cortical thymic stromal cells retains strong Pax1 expression. Expression of Pax1 in thymus epithelium is necessary for establishing the thymus microenvironment required for normal T cell maturation. Mutations in the Pax-1 gene in undulated mice affect not only the total size of the thymus but also the maturation of thymocytes. The number of thymocytes is reduced about 2- to 5-fold, affecting mainly the CD4+8+ immature and CD4+ mature thymocyte subsets. The expression levels of major thymocyte surface markers remains unchanged with the exception of Thy-1 which was found to be expressed at 3- to 4-fold higher levels. [less ▲]

Detailed reference viewed: 77 (1 UL)
Peer Reviewed
See detailMHC-genotyping of IDDM patients in Luxembourg. Evidence for a pediatric patient subgroup.
Hentges, F. R.; Michel, G. H.; Hoffmann, A. J. et al

in Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg (1996), 133(1), 5-12

[No abstract available]

Detailed reference viewed: 67 (0 UL)
Peer Reviewed
See detailNeuropeptides and their receptors in the environment of nociceptors: Where and why?
Schmidt, Robert; Hanesch, Ulrike UL

in Neuropeptides (1996)

Detailed reference viewed: 26 (0 UL)
Peer Reviewed
See detailWachstum und Wandel: Die «neue» Wachstumstheorie als Theorie wirtschaftlicher Entwicklung
Klump, Rainer UL

in ORDO: Jahrbuch für die Ordnung von Wirtschaft und Gesellschaft (1996)

Detailed reference viewed: 133 (1 UL)
See detailHauptströmungen und Tendenzen der Schweizer Pestalozzi-Forschung
Tröhler, Daniel UL

in Pädagogische Rundschau (1996), 50(1), 59-74

Detailed reference viewed: 61 (0 UL)
See detailUmweltmanagement. Neue Ansätze durch EG-Öko-Audit und DIN-ISO 14001.
Ankele, Kathrin; Hesse, Markus UL

in Internationales Verkehrswesen (1996), 48(9), 39-44

Detailed reference viewed: 95 (0 UL)
See detailJugend und Politik
Willems, Helmut UL; Gille, Martina

in Jugendhilfe Report (1996), (2), 35-35

Detailed reference viewed: 65 (0 UL)
Peer Reviewed
See detailThe HSSP database of protein structure sequence alignments
Schneider, Reinhard UL; Sander, C.

in Nucleic Acids Research (1996), 24(1), 201-205

HSSP is a derived database merging structural three dimensional (3-D) and sequence one dimensional (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database ... [more ▼]

HSSP is a derived database merging structural three dimensional (3-D) and sequence one dimensional (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment of all available homologues and a sequence profile characteristic of the family. The list of homologues is the result of a database search in Swissprot using a position-weighted dynamic programming method for sequence profile alignment (MaxHom). The database is updated frequently. The listed homologues are very likely to have the same 3-D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of aligned sequence families, but also a database of implied secondary and tertiary structures covering 27% of all Swissprotstored sequences. [less ▲]

Detailed reference viewed: 116 (0 UL)
Peer Reviewed
See detailDas Verhältnis Jugendlicher und junger Erwachsener zur Politik: Normalisierung oder Krisenentwicklung?
Willems, Helmut UL; Gille, Martina; Krüger, Winfried et al

in Aus Politik und Zeitgeschichte (1996), (19), 3-17

Detailed reference viewed: 107 (1 UL)
Peer Reviewed
See detailPax genes and sclerotome induction
Balling, Rudi UL; Neubüser, A; Christ, B

in Seminars in Cell and Developmental Biology (1996), (7), 129-136

Detailed reference viewed: 53 (3 UL)
Full Text
Peer Reviewed
See detailBrownian motion and the formation of singularities in the heat flow for harmonic maps
Thalmaier, Anton UL

in Probability Theory and Related Fields (1996), 105(3), 335-367

Detailed reference viewed: 252 (5 UL)
Peer Reviewed
See detailAn Experiment for Truly Parallel Logic Programming
Efthivoulidis, G.; Vlassis, Nikos UL; Tsanakas, P. et al

in Journal of Intelligent and Robotic Systems (1996), 16(2), 169-184

Detailed reference viewed: 111 (1 UL)
See detailWirtschaftsverkehr. Stadtlogistik zum öffentlichen Thema machen!
Hatzfeld, Ulrich; Hesse, Markus UL

in Informationen zur Raumentwicklung (1996), (7/8), 417-436

Detailed reference viewed: 116 (0 UL)
Peer Reviewed
See detailThe Relative Abundance of Brotheas amazonicus (Chactidae, Scorpiones) in Different Habitat Types of a Central Amazon Rainforest
Hoefer, Hubert; Wollscheid-Lengeling, Evi UL; Gasnier, Thierry

in Journal of Arachnology (1996), 24(1), 34-38

Detailed reference viewed: 42 (1 UL)
Peer Reviewed
See detailA role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.
Akasaka, T.; Kanno, M.; Balling, Rudi UL et al

in Development (1996), 122(5), 1513-22

Segment identity in both invertebrates and vertebrates is conferred by spatially restricted distribution of homeotic gene products. In Drosophila, the expression of Homeobox genes during embryogenesis is ... [more ▼]

Segment identity in both invertebrates and vertebrates is conferred by spatially restricted distribution of homeotic gene products. In Drosophila, the expression of Homeobox genes during embryogenesis is initially induced by segmentation gene products and then maintained by Polycomb group and Trithorax group gene products. Polycomb group gene homologs are conserved in vertebrates. Murine mel-18 and closely related bmi-1 are homologous to posterior sex combs and suppressor two of zeste. Mel-18 protein mediates a transcriptional repression via direct binding to specific DNA sequences. To gain further insight into the function of Mel-18, we have inactivated the mel-18 locus by homologous recombination. Mice lacking mel-18 survive to birth and die around 4 weeks after birth after exhibiting strong growth retardation. Similar to the Drosophila posterior sex combs mutant, posterior transformations of the axial skeleton were reproducibly observed in mel-18 mutants. The homeotic transformations were correlated with ectopic expression of Homeobox cluster genes along the anteroposterior axis in the developing paraxial mesoderm. Surprisingly, mel-18-deficient phenotypes are reminiscent of bmi-1 mutants. These results indicate that the vertebrate Polycomb group genes mel-18 and bmi-1, like Drosophila Polycomb group gene products, might play a crucial role in maintaining the silent state of Homeobox gene expression during paraxial mesoderm development. [less ▲]

Detailed reference viewed: 82 (1 UL)
See detailEin Brief über den »Phöbus«. Adam Müller an den Verleger Reimer, 23.1.1801
Amann, Wilhelm UL

in Brandenburger Kleist-Blätter (1996), 6

Detailed reference viewed: 412 (0 UL)
See detailSzLB – Skala zur Lebensbewertung (SLB).
Ferring, Dieter UL; Filipp, Sigrun-Heide; Schmidt, Katharina

in Zeitschrift für Differentielle und Diagnostische Psychologie (1996), 17(3)

Detailed reference viewed: 218 (0 UL)