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See detailBespreking van R.V. Arcilla, For the Love of Perfection.
Biesta, Gert UL

in Comenius (1997), 17(2), 168-171

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See detailAlgorithms For Phylogeny Reconstruction In a New Mathematical Model
Lenzini, Gabriele UL; Marianelli, Silvia

in Calcolo (1997), 1-4(34), 1-24

The evolutionary history of a set of species is represented by a tree called phylogenetic tree or phylogeny. Its structure depends on precise biological assumptions about the evolution of species ... [more ▼]

The evolutionary history of a set of species is represented by a tree called phylogenetic tree or phylogeny. Its structure depends on precise biological assumptions about the evolution of species. Problems related to phylogeny reconstruction (i.e., finding a tree representation of information regarding a set of items) are widely studied in computer science. Most of these problems have found to be NP-hard. Sometimes they can solved polynomially if appropriate restrictions on the structure of the tree are fixed. This paper summarizes the most recent problems and results in phylogeny reconstruction, and introduces an innovative tree model, called Phylogenetic Parsimonious Tree, which is justified by significant biological hypothesis. Using PPT two problems are studied: the existence and the reconstruction of a tree both when sequences of characters and partial order on interspecies distances are given. We rove complexity results that confirm the hardness of this class of problems. [less ▲]

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See detailPhases and phase transitions of KPF6
Huber, P.; Krummeck, H.; Baller, Jörg UL et al

in Ferroelectrics (1997), 203(1), 211-219

Potassium hexafluorophosphate KPF6 has been investigated by X-ray powder diffraction, calorimetry and Brillouin spectroscopy. With decreasing temperature, the crystal shows a sequence of phases: NaCl-type ... [more ▼]

Potassium hexafluorophosphate KPF6 has been investigated by X-ray powder diffraction, calorimetry and Brillouin spectroscopy. With decreasing temperature, the crystal shows a sequence of phases: NaCl-type cubic-monoclinic-monoclinic with two-phase coexistence regions in between. In the cubic phase the elastic constants have been determined. c44 and c12 show a slight softening. [less ▲]

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See detailNote on duopolistic vertical restraints
Irmen, Andreas UL

in European Economic Review (1997), 41(8), 1559-1567

No abstract is available for this item.

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See detailElectrical Behaviour of the InP/InGaAs Based MSM-2DEG Diode
Marso, Michel UL; Horstmann, M.; Hardtdegen, H. et al

in Solid-State Electronics (1997), 41(1997), 25-31

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See detailDe toekomst van de historische pedagogiek.
Selten, P. J. H.; Bakker, P. C. M.; Biesta, Gert UL

in Comenius (1997), 17(3), 195-199

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See detailSequence analysis of the nucleocapsid gene of measles virus isolates from South Africa identifies a new genotype
Kreis, Stephanie UL; Vardas, E.; Whistler, T.

in Journal of General Virology (1997), 78(7), 1581-1587

Sequence analysis was performed on 20 measles virus (MV) isolates from South Africa, five of which were obtained between 1986 and 1989 and 15 isolates collected during the 1994/95 measles season. A 590 bp ... [more ▼]

Sequence analysis was performed on 20 measles virus (MV) isolates from South Africa, five of which were obtained between 1986 and 1989 and 15 isolates collected during the 1994/95 measles season. A 590 bp fragment of the carboxyl terminus of the nucleocapsid (N) was amplified by PCR and subjected to sequence and phylogenetic analysis. Comparison of the South African MV strains with those previously described revealed that at least two distinct groups of wild-type (wt) MV exist, one of which has been circulating since 1986. The major genotype (I) was represented by the more recent isolates which showed three characteristic amino acid substitutions. Furthermore, three vaccine-like viruses with sequences very similar to the Edmonston wt strain were identified. Phylogenetic analysis of 100 MV strains allowed the assignment of new definitions for MV genotypes and subgroups. Employing these definitions, the majority of South African isolates analysed here formed a new genotype. [less ▲]

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See detailAnalysis of Subspace System Identification Methods Based on Instrumental Variables and Subspace Fitting
Viberg, Mats; Wahlberg, Bo; Ottersten, Björn UL

in Automatica (1997), 33

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See detailAccuracy assessment of recent ocean tide models
Shum, C. K.; Woodworth, P. L.; Andersen, O. B. et al

in Journal of Geophysical Research (1997), 102(C11), 25173-25194

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See detailThe HSSP database of protein structure-sequence alignments
Schneider, Reinhard UL; deDaruvar, A.; Sander, C.

in Nucleic Acids Research (1997), 25(1), 226-230

HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment ... [more ▼]

HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment of all available homologues and a sequence profile characteristic of the family. The list of homologues is the result of a database search in SwissProt using a position-weighted dynamic programming method for sequence profile alignment (MaxHom). The database is updated frequently. The listed homologues are very likely to have the same 3-D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of aligned sequence families, but also a database of implied secondary and tertiary structures covering 29% of all SwissProt-stored sequences. [less ▲]

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See detailWorld Wide Web caching: the application-level view of the Internet
Baentsch, Michael; Baum, Lothar; Molter, Georg et al

in IEEE Communications Magazine (1997), 35(6), 170-178

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See detailPedestrian guide to analyzing sequence databases
Rost, B.; Schneider, Reinhard UL; Sander, C.

in WWW-publication (1997)

Over the past few years our means of communication have changed rapidly due to the growth of the World Wide Web (WWW). The Web enables molecular biologists to immediately access databases, scan literature ... [more ▼]

Over the past few years our means of communication have changed rapidly due to the growth of the World Wide Web (WWW). The Web enables molecular biologists to immediately access databases, scan literature, find information about related research and researchers, and to trace cell cultures. Wet-lab biologists can uncover information about the protein of interest without having to become experts in sequence analysis. Here, we present a variety of tools; provide an overview of the state-of-the art in sequence analysis; and described some of the principles of the methods. [less ▲]

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See detailSpace-charge controlled conduction in low-temperature-grown molecular-beam epitaxial GaAs,
Kordoš, P.; Marso, Michel UL; Förster, A. et al

in Applied Physics Letters (1997), 71

Current transport in low-temperature (LT) molecular-beam epitaxial GaAs grown at 200-300 °C on an n+ GaAs substrate is studied by means of current–voltage–temperature characteristics. The resistivity of ... [more ▼]

Current transport in low-temperature (LT) molecular-beam epitaxial GaAs grown at 200-300 °C on an n+ GaAs substrate is studied by means of current–voltage–temperature characteristics. The resistivity of LT GaAs at low electric fields is rho>108 Ohm cm, much higher than resulting from van der Pauw measurements. It is found that the measured resistivity decreases with increasing the LT GaAs thickness. This is explained by space-charge effect in the vicinity of n+/LT GaAs junction and subsequent suppression of hopping conduction in the high-field junction region. [less ▲]

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See detailEtude de differentes methodes pour la mise en evidence des autoanticorps anti-glutamate-decarboxylase associes au developpement du diabete insulinodependant
Humbel, R. L.; Guillaume, A. C.; Schmit, P. et al

in Immuno-Analyse et Biologie Specialisee (1997), 12(5), 275-279

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react ... [more ▼]

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react predominantly with the native GAD. Various methods have been studied (radio immunoassay [RIA] and enzyme- linked immunosorbent assay [ELISA]). It was observed that at the present time only RIA-tests, in which GAD is presented in fluid phase, are able to detect antibodies. [less ▲]

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See detailTraditionsbewusstsein - eine wenig beachtete Grundhaltung
Tröhler, Daniel UL

in Infos und Akzente (1997), (17), 11-14

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See detailStaatliche Lehrerbildung in der Zeit der Helvetik und die Rolle Pestalozzis
Tröhler, Daniel UL

in Beiträge zur Lehrerbildung (1997), 15(3), 293-303

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See detailSolarthermische Energie in Andalusien - Hindernisse bei der Nutzung eines endogenen Potentials
Helfer, Malte UL

in Geographische Rundschau (1997), 49(6), 348-354

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See detailDer Grossvater Pestalozzis als pietistisch-pädagogischer Vermittler? Einleitung
Tröhler, Daniel UL

in Neue Pestalozzi-Blätter (1997), 3(1), 28-29

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See detailAlter Wein in neuen Schläuchen? Agenda 21 und Stadtentwicklung -
Hesse, Markus UL

in Politische Ökologie : die Reihe für Querdenker und Vordenkerinnen (1997), (52), 38-41

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See detailA single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
Behrmann, Iris UL; Janzen, C.; Gerhartz, C. et al

in Journal of Biological Chemistry (1997), 272(8), 5269-74

We established a system of receptor chimeras that enabled us to induce heterodimerization of different cytoplasmic tails. Fusion constructs were created that are composed of the extracellular parts of the ... [more ▼]

We established a system of receptor chimeras that enabled us to induce heterodimerization of different cytoplasmic tails. Fusion constructs were created that are composed of the extracellular parts of the interleukin-5 receptor alpha and beta chains, respectively, and the transmembrane and intracellular parts of gp130, the signal transducing chain of the interleukin-6 receptor complex. In COS-7 transfectants we observed a dose-dependent interleukin-5-inducible STAT1 activation for which the presence of both the alpha and the beta chain chimera was needed. No STAT activity was detected if one of the cytoplasmic tails of the receptor complex was deleted, indicating that STAT activity resulted from a receptor dimer rather than from higher receptor aggregates. We further investigated whether dimerization of STAT1 depends on the juxtaposition of two STAT recruitment modules in a receptor complex. We show that a receptor dimer with only a single STAT1 docking site was still able to lead to STAT1 activation. This indicates that the formation of a paired set of STAT binding sites in a receptor complex is not the prerequisite for STAT factor dimerization. Our findings are discussed in view of alternative STAT dimerization models. [less ▲]

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See detailOnmogelijke opvoeding. Kanttekeningen bij de pedagogische overdrachtsmetafoor.
Biesta, Gert UL

in Comenius (1997), 17(4), 312-324

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See detailEffects of moexiprilat on oestrogen-stimulated cardiac fibroblast growth.
Grohe, C.; Kahlert, S.; Lobbert, K. et al

in British journal of pharmacology (1997), 121(7), 1350-4

1. The effects of 2-2-(1-(ethoxycarbonyl)-3-phenylpropyl)-[amino-oxopropyl]-6,7-dimethoxy- 1,2,3,4-tetrahydroisoquinoline-3 carboxylic acid (moexiprilat), 17beta-oestradiol (E2), oestrone (ES) and ... [more ▼]

1. The effects of 2-2-(1-(ethoxycarbonyl)-3-phenylpropyl)-[amino-oxopropyl]-6,7-dimethoxy- 1,2,3,4-tetrahydroisoquinoline-3 carboxylic acid (moexiprilat), 17beta-oestradiol (E2), oestrone (ES) and angiotensin II (AII) on growth and activation of oestrogen receptors and the immediate-early gene egr-1 were investigated in neonatal rat cardiac fibroblasts of female and male origin. 2. In BrdU proliferation assays, oestrone (10(-7)- 10(-9) M) stimulated cardiac fibroblast growth in a concentration-dependent fashion (maximum at 10(-7) M, 4.0 fold +/- 0.14 in female and 3.1 fold +/- 0.06 in male cells, n=9, P<0.05), while E2 (10(-7)-10(-9) M) had no effect. Moexiprilat (10(-7)M) completely inhibited oestrone-induced cardiac fibroblast growth. 3. Angiotensin II (10(-7) M) induced cardiac fibroblast growth (female 4.1 fold +/- 0.1/male 3.9 fold +/- 0.2; n=9, P<0.05). Angiotensin II induced oestrogen receptor (maximum 21.8 fold at 60 min) and egr-1 (maximum 47.5 fold at 60 min) expression in a time-dependent fashion. 4. In immunoblot experiments, oestrogen activated oestrogen receptor (ES: 12.8 fold +/- 2.0; E2: 14.7 fold +/- 4.9; n=3, P<0.05) and egr-1 (ES: 5.1 fold, +/- 0.24; E2: 3.8 fold, +/- 0.25; n=3, P<0.05) expression. The induction of oestrogen receptor and egr-1 protein expression was time-dependent and inhibited by moexiprilat. 5. Our results show that oestrone and 17beta-oestradiol reveal a significant difference in their potential to activate cardiac fibroblast growth in female and male cells and that oestrone-stimulated growth is inhibited by moexiprilat. The inhibition of oestrone-stimulated cardiac fibroblast growth by moexiprilat may contribute to the beneficial effects seen in postmenopausal women with hypertensive heart disease treated with ACE inhibitors. [less ▲]

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See detailSubjektives Wohlbefinden im Alter: Struktur- und Stabilitätsanalysen.
Ferring, Dieter UL; Filipp, Sigrun-Heide

in Psychologische Beiträge (1997), 39(3)

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See detailSchule und Sport aus der Sicht jugendlicher Vereinsmitglieder - ein internationaler Vergleich
Steffgen, Georges UL; Schwenkmezger, Peter; Fröhling, Roland

in Sportunterricht (1997), 46(7), 292-300

The findings are presented of an international comparative study of youth sports club members to determine their perspectives on the relationship between school and sport, and the influence of physical ... [more ▼]

The findings are presented of an international comparative study of youth sports club members to determine their perspectives on the relationship between school and sport, and the influence of physical education on sport participation and membership of sports clubs. Participants in the study comprised two groups of 344 sports club members and school pupils from Luxembourg and Germany. Differences in terms of age, sex and school type were taken into account. The main findings indicate that school and physical education in both countries only have a slight, indirect influence on young people's decisions to become members of sports clubs and participate in sport. Indeed, the pressures of school may in some cases be an obstacle to intensive sports activity and training outside school. This is particularly so in Luxembourg where students often have to refuse participation in sports competitions and training because of the pressures of school work. Some final thoughts are presented on ways in which school and physical education could become more supportive of youth sport training and club membership, and could give greater encouragement to young people to succeed in competitive and high level sport. [less ▲]

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See detailLes exigences de prix dans les contrats internationaux
Prüm, André UL

in Cahiers de Droit de l'Entreprise (1997), (5),

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See detailSuperheavy nuclei in selfconsistent nuclear calculations
Rutz, K.; Bender, M.; Bürvenich, T. et al

in Physical Review. C, Nuclear Physics (1997), 56(1), 238-243

The shell structure of superheavy nuclei is investigated within various parametrizations of relativistic and nonrelativistic nuclear mean-field models. The heaviest known even-even nucleus 156 264Hs108 is ... [more ▼]

The shell structure of superheavy nuclei is investigated within various parametrizations of relativistic and nonrelativistic nuclear mean-field models. The heaviest known even-even nucleus 156 264Hs108 is used as a benchmark to estimate the predictive value of the models. From that starting point, doubly magic spherical nuclei are searched in the region Z51102140 and N5134–298. They are found at (Z5114 , N5184), (Z5120 , N5172), or at (Z5126 , N5184), depending on the parametrization. [less ▲]

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See detailAntagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation.
Neubuser, A.; Peters, H.; Balling, Rudi UL et al

in Cell (1997), 90(2), 247-55

Vertebrate organogenesis is initiated at sites that are often morphologically indistinguishable from the surrounding region. Here we have identified Pax9 as a marker for prospective tooth mesenchyme prior ... [more ▼]

Vertebrate organogenesis is initiated at sites that are often morphologically indistinguishable from the surrounding region. Here we have identified Pax9 as a marker for prospective tooth mesenchyme prior to the first morphological manifestation of odontogenesis. We provide evidence that the sites of Pax9 expression in the mandibular arch are positioned by the combined activity of two signals, one (FGF8) that induces Pax9 expression and the other (BMP2 and BMP4) that prevents this induction. Thus it appears that the position of the teeth is determined by a combination of two different types of signaling molecules produced in wide but overlapping domains rather than by a single localized inducer. We suggest that a similar mechanism may be used for specifying the sites of development of other organs. [less ▲]

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See detailRevêtements de courbes elliptiques à multiplication complexe par des courbes hyperelliptiques et sommes de caractères
Leprévost, Franck UL; Morain, François

in Journal of Number Theory (1997), 64(2), 165-182

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See detailPsychophysiological responses to food exposure: an experimental study in binge eaters
Vögele, Claus UL; Florin, Irmela

in International Journal of Eating Disorders (1997), (21), 147-157

Objective: The aim of the present study was to investigate psychophysiological responses to food exposure in binge eaters. Method: Thirty female volunteers reporting regular binge attacks were compared ... [more ▼]

Objective: The aim of the present study was to investigate psychophysiological responses to food exposure in binge eaters. Method: Thirty female volunteers reporting regular binge attacks were compared with 30 nonbinge eaters. Subjects attended individually for the single laboratory session. Continuous measures of heart rate (HR), blood pressure (BP), electroder- mal activity (EDA), and respiration rate were taken during rest and exposure to their favorite binge food. In addition, psychophysiological monitoring continued while subjects were al- lowed to eat after food exposure. Participants also completed inventories assessing restrained eating style (FEV, Revised Restraint Scale). Ratings of nervousness, distress, desire to binge, and hunger were collected repeatedly throughout the experiment. Results: The results indi- cate higher psychophysiological arousal in binge eaters than in nonbinge eaters. Binge eaters maintained a higher arousal level in BP and EDA throughout the food exposure trial than controls. HR during food exposure predicted the relative amount of food consumed during the eating trial across all subjects. This relationship, however, was more pronounced in binge eaters than controls and in restrained compared to unrestrained binge eaters. Discussion: The implications of these results are discussed in terms of conditioning and arousal models of cue reactivity in binge eating. © 1997 by John Wiley & Sons, Inc. Int J Eat Disord 21: 147–157, 1997. [less ▲]

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See detailThe role of actin binding proteins in epithelial morphogenesis: models based upon Listeria movement.
Golsteyn, R. M.; Louvard, D.; Friederich, Evelyne UL

in Biophysical chemistry (1997), 68(1-3), 73-82

We summarize recent findings on the organization of the protein actin in eucaryotic cells. In particular we focus on how actin can be used to generate a vectorial force that is required for cell movement ... [more ▼]

We summarize recent findings on the organization of the protein actin in eucaryotic cells. In particular we focus on how actin can be used to generate a vectorial force that is required for cell movement. These forces arise from protein molecules that recruit actin to the plasma membrane in such a manner that actin filaments extend outward from the cell body. This type of actin dependent force generation has been described in a nucleation-release model, which is one of several models currently being tested to explain actin dependent cell movement. Data in support of this model has arisen unexpectedly from studies of an intracellular bacteria, Listeria monocytogenes. This bacteria uses actin to propel itself during infection of eucaryotic cells. By studying Listeria movement, the roles of several eucaryotic actin interacting proteins have been identified. One of these is zyxin, a human protein that shares important structural and possibly functional properties with ActA, an actin dependent force generating protein of Listeria. We intend to test the function of these and other actin interacting proteins in a simplified system that should facilitate precise measurement of their properties of force generation in vitro. [less ▲]

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See detailMaximum Likelihood Array Processing in Spatially Correlated Noise Fields Using Parametrized Signals
Viberg, Mats; Stoica, Petre; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (1997), 45(4), 9961004

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See detailMethodische Bemerkungen zu Kontextualisierung und Wirkungsgeschichte in der pädagogischen Historiographie
Tröhler, Daniel UL

in Neue Pestalozzi-Blätter (1997), 3(2), 28-29

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See detailCapacity Utilization and Market Power
Fagnart, J.F.; Licandro, O.; Sneessens, Henri UL

in Journal of Economic Dynamics and Control (1997), 22

We propose a theoretical macroeconomic model where capacity underutilization follows from idiosyncratic demand uncertainty at the time monopolistic firms must choose their productive capacity. After their ... [more ▼]

We propose a theoretical macroeconomic model where capacity underutilization follows from idiosyncratic demand uncertainty at the time monopolistic firms must choose their productive capacity. After their investment decision, firms facing a low demand will typically prefer to run excess capacities rather than reduce their profit margin; firms at full capacity will respond to demand fluctuations solely by price adjustments. We show that the proportion of firms with idle capacities influences crucially the short-run response of the economy to exogenous disturbances and, in particular, the relative importance of price and quantity adjustments. [less ▲]

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See detailOn the differentiation of heat semigroups and Poisson integrals
Thalmaier, Anton UL

in Stochastics and Stochastics Reports (1997), 61(3-4), 297-321

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See detailSequence analysis of the Methanococcus jannaschii genome and the prediction of protein function
Andrade, M.; Casari, G.; deDaruvar, A. et al

in Computer Applications in the Biosciences [=CABIOS] (1997), 13(4), 481-483

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See detailRetrospektive Bewertungen des eigenen Lebens: LZG – Lebenszufriedenheits-Graph.
Ferring, Dieter UL; Filipp, Sigrun-Heide

in Zeitschrift für Entwicklungspsychologie und Padagogische Psychologie (1997), 29(1)

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See detailIsolation of the Pax9 cDNA from adult human esophagus.
Peters, H.; Schuster, G.; Neubuser, A. et al

in Mammalian Genome (1997), 8(1), 62-4

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See detailHuman umbilical cord blood-derived eosinophils cultured in the presence of IL-3 and IL-5 respond to fMLP with [Ca2+]i variation and O2- production
Zardini, D. M.; Heuschling, Paul UL; Gallois, A. et al

in Journal of Immunological Methods (1997), 205(1), 1-9

In the presence of interleukin-3 and interleukin-5, eosinophil precursors from human umbilical cord blood mononuclear cells were regularly differentiated into mature eosinophil-like cells expressing ... [more ▼]

In the presence of interleukin-3 and interleukin-5, eosinophil precursors from human umbilical cord blood mononuclear cells were regularly differentiated into mature eosinophil-like cells expressing normal morphology and cyanide-resistant peroxidase. O2- production and [Ca2+]i rise were measured in these in vitro differentiated eosinophils after fMLP stimulation; with dihydrorhodamine-123 and fura-2, respectively. Umbilical cord blood-derived eosinophils responded to fMLP (0.01 nM to 3 microM) with a concentration-dependent production of O2- (EC50 = 63.1 +/- 17.2 nM; Emax = 71.0 +/- 6.2 pmol/min/10(6) cells). O2- production was correlated with an fMLP concentration-dependent increase in [Ca2+]i (EC50 = 32.5 +/- 14.9 nM; Emax = 200.0 +/- 23.9 nM). These results indicate that human umbilical cord blood-derived eosinophils demonstrate functional characteristics similar to adult human peripheral blood eosinophils after activation by fMLP. Therefore, the large numbers of eosinophils (2-3 x 10(6)/ml cord blood) which can be obtained by culture of human cord blood mononuclear cells may serve as a useful model for future studies which will provide insight into the pathogenesis of diseases associated with eosinophils. [less ▲]

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See detailMeasles virus transmission from infected to immune individuals - Implications for measles control and elimination
Vardas, E.; Andre, M.; Kreis, Stephanie UL et al

in South African Medical Journal (1997), 87(12), 1709

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See detailRezension des Artikels: Neuere Forschungsarbeiten zur Kontaktlinguistik (Plurilingua XIX) von Moelleken, WW. & Weber P.J.
Hu, Adelheid UL

in Tertium Comparationis. Journal für Internationale Bildungsforschung (1997), 4(1), 71-73

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See detailProcessus de raisonnement et enseignement de l’algèbre au premier degré du secondaire
Vlassis, Joëlle UL; DEMONTY, I

in Informations Pédagogiques (1997), 38

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See detailCharacterization of new proteins found by analysis of short open reading frames from the full yeast genome
Andrade, M. A.; Daruvar, A.; Casari, G. et al

in Journal of Yeast and Fungal Research (1997), 13(14), 1363-1374

We have analysed short open reading frames (between 150 and 300 base pairs long) of the yeast genome (Saccharomyces cerevisiae) with a two-step strategy. The first step selects a candidate set of open ... [more ▼]

We have analysed short open reading frames (between 150 and 300 base pairs long) of the yeast genome (Saccharomyces cerevisiae) with a two-step strategy. The first step selects a candidate set of open reading frames from the DNA. sequence based on statistical evaluation of DNA and protein sequence properties. The second step filters the candidate set by selecting open reading frames with high similarity to other known sequences (from any organism). As a result, we report ten new predicted proteins not present in the current sequence databases. These include a new alcohol dehydrogenase, a protein probably related to the cell cycle, as well as a homolog of the prokaryotic ribosomal protein L36 likely to be a mitochondrial ribosomal protein coded in the nuclear genome. We conclude that the analysis of short open reading frames leads to biologically interesting discoveries, even though the quantitative yield of new proteins is relatively low. [less ▲]

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See detailEnhancing the Web's infrastructure: from caching to replication
Baentsch, Michael; Baum, Lothar; Molter, Georg et al

in IEEE Internet Computing (1997), 1(2), 18-27

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See detailMythos Menalk? Neue Fragen zu Pestalozzis Jugend
Tröhler, Daniel UL

in Neue Pestalozzi-Blätter (1997), 3(2), 24-27

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See detailCardiac myocytes and fibroblasts contain functional estrogen receptors.
Grohe, C.; Kahlert, S.; Lobbert, K. et al

in FEBS letters (1997), 416(1), 107-12

Gender-based differences found in cardiovascular diseases raise the possibility that estrogen may have direct effects on cardiac tissue. Therefore we investigated whether cardiac myocytes and fibroblasts ... [more ▼]

Gender-based differences found in cardiovascular diseases raise the possibility that estrogen may have direct effects on cardiac tissue. Therefore we investigated whether cardiac myocytes and fibroblasts express functional estrogen receptors. Immunofluorescence demonstrated estrogen receptor protein expression in both female and male rat cardiac myocytes and fibroblasts. Nuclear translocation of the estrogen receptor protein was observed after stimulation of cardiomyocytes with 17beta-estradiol (E2). Cells transfected with an estrogen-responsive reporter plasmid showed that treatment with E2 induced a significant increase in reporter activity. Furthermore, E2 induced a significant increase in expression of the estrogen receptors alpha and beta, progesterone receptor and connexin 43 in cardiac myocytes. Cardiac myocytes and fibroblasts contain functional estrogen receptors and estrogen regulates expression of specific cardiac genes. These data suggest that gender-based differences in cardiac diseases may in part be due to direct effects of estrogen on the heart. [less ▲]

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See detailSegment-specific expression of the gap junction gene connexin 31 during hindbrain development
Dahl, E; Willecke, K; Balling, Rudi UL

in Development Genes & Evolution (1997), (207), 359-361

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See detail0.1 µm T-gate Al-free InP/InGaAs/InP pHEMTs for W-Band Applications Using a Nitrogen Carrier for LP-MOCVD Growth
Schimpf, K.; Sommer, M.; Horstmann, M. et al

in IEEE Electron Device Letters (1997), 18

We report on the dc and RF performance of HEMT’s based on the Al-free material system InP/InGaAs/InP. These structures were grown by LP-MOCVD using a nitrogen carrier. The influence of gate length and ... [more ▼]

We report on the dc and RF performance of HEMT’s based on the Al-free material system InP/InGaAs/InP. These structures were grown by LP-MOCVD using a nitrogen carrier. The influence of gate length and channel composition on the performance of these devices is investigated.We demonstrate that optimum dc and RF performance using highly strained channels can be obtained only if additional composite channels are grown. The cutoff frequencies fT =160 GHz and fmax=260 GHz for a 0.1- um T-gate device indicate the suitability of our devices for W-Band applications. [less ▲]

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See detailGeometry-dependent scattering through ballistic microstructures: Semiclassical theory beyond the stationary-phase approximation
Wirtz, Ludger UL; Tang, J. Z.; Burgdorfer, J.

in Physical Review. B (1997), 56(12), 7589-7597

The conductance of a ballistic microstructure shows strong fluctuations as a function of the Fermi wave number. We present a semiclassical-theory that describes these fluctuations in terms of bundles of ... [more ▼]

The conductance of a ballistic microstructure shows strong fluctuations as a function of the Fermi wave number. We present a semiclassical-theory that describes these fluctuations in terms of bundles of short trajectories. These trajectories provide the dominant contribution to electron transport through a weakly open microstructure. For the coupling between the quantum wires and the cavity, contributions beyond the stationary phase approximation are taken into account giving rise to diffraction effects. A comparison with full quantum calculations for st rectangular billiard is made. The peak positions of the power spectrum agree very well between the quantum and semiclassical theories. Numerical evidence is found for the breakdown of the semiclassical approximation for long paths. A simple explanation in terms of the dispersion of the semiclassical wave packet in the interior of the cavity is proposed. [less ▲]

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See detailPredictions of crustal deformation and of geoid and sea level variability caused by oceanic at atmospheric loading
van Dam, Tonie UL; Wahr, J.; Chao, Y. et al

in Geophysical Journal International (1997), 129(3), 507-517

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See detailRapid identification of measles virus strains by the heteroduplex mobility assay
Kreis, Stephanie UL; Whistler, T.

in Virus Research (1997), 47(2), 472197-203

The continued endemic presence of measles virus (MV), and the large number of isolates which are made in South Africa each year, demanded the use of a rapid and reliable pre-screening technique to select ... [more ▼]

The continued endemic presence of measles virus (MV), and the large number of isolates which are made in South Africa each year, demanded the use of a rapid and reliable pre-screening technique to select isolates for molecular epidemiological studies by sequence analysis. The heteroduplex mobility assay (HMA) was used to genetically characterize 47 MV isolates collected from three different provinces in South Africa, made between 1986 and 1995. The carboxyl-terminal 590 nt of the nucleocapsid (N) gene - the most variable region of the genome - was amplified by polymerase chain reaction (PCR) and subsequently subjected to HMA analysis for initial genotyping. The results showed three different patterns of heteroduplex formation by gel electrophoresis, representing two distinct wild-type lineages and one group of vaccine-like viruses. Comparison of HMA results with phylogenetic analysis of sequence data for several of the South African MV strains showed a complete correlation of results. The HMA proved to be a useful tool for screening MV isolates for use in molecular epidemiological studies. [less ▲]

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See detailA Return to the Dewey-Russell Opposition.
Biesta, Gert UL

in [Review Essay] Culture & Psychology (1997), 3(1), 99-105

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See detailThe nature of the starter unit for the rapamycin polyketide synthase
König, Ariane UL; Schwecke, T.; Molnár, I. et al

in Angewandte Chemie International Edition (1996), 35(19), 2249-2251

A remarkably high level of incorporation is observed when 2,2,5,5-tetradeutero -3,4- dihydroxycyclo -hexanecarboxylic acid is fed to the rapamycin-producing organism. Intriguingly, however, analysis of ... [more ▼]

A remarkably high level of incorporation is observed when 2,2,5,5-tetradeutero -3,4- dihydroxycyclo -hexanecarboxylic acid is fed to the rapamycin-producing organism. Intriguingly, however, analysis of the gene sequence for the rapamycin polyketide synthase has suggested that the free acid may not normally be involved in rapamycin biosynthesis. [less ▲]

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See detailOrganisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the genes flanking the polyketide synthase
Aparicio, J. F.; Molnár, I.; Schwecke, T. et al

in Gene (1996), 169(1), 1-7

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme ... [more ▼]

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme activities, each module catalysing a specific round of polyketide chain extension. Detailed sequence comparison between these protein modules has allowed further characterisation of aa that may be important in catalysis or specificity. The acyl-carrier protein (ACP), beta-ketoacyl-ACP synthase (KS) and acyltransferase (AT) domains (the core domains) have an extremely high degree of mutual sequence homology. The KS domains in particular are almost perfect repeats over their entire length. Module 14 shows the least homology and is unique in possessing only core domains. The enoyl reductase (ER), beta-ketoacyl-ACP reductase (KR) and dehydratase (DH) domains are present even in certain modules where they are not apparently required. Four DH domains can be recognised as inactive by characteristic deletions in active site sequences, but for two others, and for KR and ER in module 3, the sequence is not distinguishable from that of active counterparts in other modules. The N terminus of RAPS1 contains a novel coenzyme A ligase (CL) domain that activates and attaches the shikimate-derived starter unit, and an ER activity that may modify the starter unit after attachment. The sequence comparison has revealed the surprisingly high sequence similarity between inter-domain 'linker' regions, and also a potential amphipathic helix at the N terminus of each multienzyme subunit which may promote dimerisation into active species. [less ▲]

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See detailOrganisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase
Aparicio, J. F.; Molnar, I.; Schwecke, T. et al

in Gene (1996), 169(1), 9-16

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme ... [more ▼]

The three giant multifunctional polypeptides of the rapamycin (Rp)-producing polyketide synthase (RAPS1, RAPS2 and RAPS3) have recently been shown to contain 14 separate sets, or modules, of enzyme activities, each module catalysing a specific round of polyketide chain extension. Detailed sequence comparison between these protein modules has allowed further characterisation of aa that may be important in catalysis or specificity. The acyl-carrier protein (ACP), beta-ketoacyl-ACP synthase (KS) and acyltransferase (AT) domains (the core domains) have an extremely high degree of mutual sequence homology. The KS domains in particular are almost perfect repeats over their entire length. Module 14 shows the least homology and is unique in possessing only core domains. The enoyl reductase (ER), beta-ketoacyl-ACP reductase (KR) and dehydratase (DH) domains are present even in certain modules where they are not apparently required. Four DH domains can be recognised as inactive by characteristic deletions in active site sequences, but for two others, and for KR and ER in module 3, the sequence is not distinguishable from that of active counterparts in other modules. The N terminus of RAPS1 contains a novel coenzyme A ligase (CL) domain that activates and attaches the shikimate-derived starter unit, and an ER activity that may modify the starter unit after attachment. The sequence comparison has revealed the surprisingly high sequence similarity between inter-domain 'linker' regions, and also a potential amphipathic helix at the N terminus of each multienzyme subunit which may promote dimerisation into active species. [less ▲]

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See detailSzLB – Skala zur Lebensbewertung (SLB).
Ferring, Dieter UL; Filipp, Sigrun-Heide; Schmidt, Katharina

in Zeitschrift für Differentielle und Diagnostische Psychologie (1996), 17(3)

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See detailRbt (Rabo torcido), a new mouse skeletal mutation involved in anteroposterior patterning of the axial skeleton, maps close to the Ts (tail-short) locus and distal to the Sox9 locus on chromosome 11.
Hustert, E.; Scherer, G.; Olowson, M. et al

in Mammalian Genome (1996), 7(12), 881-5

Rbt (Rabo torcido) is a new semidominant mouse mutant with a variety of skeletal abnormalities. Heterozygous Rbt mutants display homeotic anteroposterior patterning problems along the axial skeleton that ... [more ▼]

Rbt (Rabo torcido) is a new semidominant mouse mutant with a variety of skeletal abnormalities. Heterozygous Rbt mutants display homeotic anteroposterior patterning problems along the axial skeleton that resemble Polycomb group and trithorax gene mutations. In addition, the Rbt mutant displays strong similarities to the phenotype observed in Ts (Tail-short), indicating also a homeotically transformed phenotype in these mice. We have mapped the Rbt locus to an interval of approximately 6 cM on mouse Chromosome (Chr) 11 between microsatellite markers D11Mit128 and D11Mit103. The Ts locus was mapped within a shorter interval of approximately 3 cM between D11Mit128 and D11Mit203. This indicates that Rbt and Ts may be allelic mutations. Sox9, the human homolog of which is responsible for the skeletal malformation syndrome campomelic dysplasia, was mapped proximal to D11Mit128. It is, therefore, unlikely that Ts and Rbt are mouse models for this human skeletal disorder. [less ▲]

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See detailEin Brief über den »Phöbus«. Adam Müller an den Verleger Reimer, 23.1.1801
Amann, Wilhelm UL

in Brandenburger Kleist-Blätter (1996), 6

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See detailA reading of Troubadour insult songs: the Comunals cycle
Leglu, Catherine UL

in Reading Medieval Studies (1996), XXII

An analysis of a cycle of aggressive songs by troubadours.

Detailed reference viewed: 76 (1 UL)
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See detailCytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
Kischkel, F. C.; Hellbardt, S.; Behrmann, Iris UL et al

in EMBO Journal (1996), 14(22), 5579-88

APO-1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to ... [more ▼]

APO-1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to oligomerized APO-1, several cytotoxicity-dependent APO-1-associated proteins (CAP) were immunoprecipitated from the apoptosis-sensitive human leukemic T cell line HUT78 and the lymphoblastoid B cell line SKW6.4. CAP1-3 (27-29 kDa) and CAP4 (55 kDa), instantly detectable after the crosslinking of APO-1, were associated only with aggregated (the signaling form of APO-1) and not with monomeric APO-1. CAP1 and CAP2 were identified as serine phosphorylated MORT1/FADD. The association of CAP1-4 with APO-1 was not observed with C-terminally truncated non-signaling APO-1. In addition, CAP1 and CAP2 did not associate with an APO-1 cytoplasmic tail carrying the lprcg amino acid replacement. Moreover, no APO-1-CAP association was found in the APO-1+, anti-APO-1-resistant pre-B cell line Boe. Our data suggest that in vivo CAP1-4 are the APO-1 apoptosis-transducing molecules. [less ▲]

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See detailVeränderungsmuster im Bewältigungsverhalten von Krebspatienten und Korrelate von Veränderungen: Ein personorientierter Ansatz.
Ferring, Dieter UL; Sommer, C.; Filipp, Sigrun-Heide

in Zeitschrift für Gesundheitspsychologie (1996), 4(4)

Detailed reference viewed: 66 (5 UL)
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See detail«Orphée à l'écran: un défi représentatif (avec Sabine Hillen)»
Roelens, Nathalie UL

in Canadian Review of Comparative Literature = Revue Canadienne de Littérature Comparée (1996)

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See detailBrownian motion and the formation of singularities in the heat flow for harmonic maps
Thalmaier, Anton UL

in Probability Theory and Related Fields (1996), 105(3), 335-367

Detailed reference viewed: 252 (5 UL)
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See detail«Les mille visages de Gilles Deleuze»
Roelens, Nathalie UL

in Restant (1996)

Detailed reference viewed: 55 (2 UL)
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See detailInterkultureller Fremdsprachenunterricht und die Heterogenität von Kulturen
Hu, Adelheid UL

in Zeitschrift für Interkulturellen Fremdsprachenunterricht (1996), 1(3), 16

Detailed reference viewed: 189 (1 UL)
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See detailThe Relative Abundance of Brotheas amazonicus (Chactidae, Scorpiones) in Different Habitat Types of a Central Amazon Rainforest
Hoefer, Hubert; Wollscheid-Lengeling, Evi UL; Gasnier, Thierry

in Journal of Arachnology (1996), 24(1), 34-38

Detailed reference viewed: 42 (1 UL)
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See detailAnalysis of limb patterning in BMP-7-deficient mice.
Hofmann, C.; Luo, G.; Balling, Rudi UL et al

in Developmental Genetics (1996), 19(1), 43-50

Bone morphogenetic proteins (BMPs) are polypeptide signaling molecules, belonging to the TGF-beta superfamily. They were originally identified by their ability to induce ectopic bone formation, but their ... [more ▼]

Bone morphogenetic proteins (BMPs) are polypeptide signaling molecules, belonging to the TGF-beta superfamily. They were originally identified by their ability to induce ectopic bone formation, but their expression patterns in embryos suggest multiple functions. BMP-7-deficient mice show among other mesodermal and skeletal patterning defects, polydactyly in the hindlimbs [Luo G, Hofmann C, Bronckers ALJJ, Sohocki M, Bradley A, Karsenty G (1995): Genes Dev 9:2808-2820; Dudley AT, Lyons KM, Robertson EJ (1995): Genes Dev 9:2795-2807]. Here we report a more detailed analysis of the limb phenotype in BMP-7-deficient mice using in situ hybridization to monitor expression of molecules implicated in patterning processes of the developing vertebrate limb. In previous studies we showed that Sonic hedgehog (Shh) was expressed normally, but Hoxd-13 expression in limb mesenchyme was lower in BMP-7 mutant limbs. Here we show that Hoxd-11 expression domains are also contracted and decreased in intensity in mutant limbs, suggesting that 5' genes of the Hoxd cluster are coordinately downregulated, while another Bmp, Bmp-2, which can be activated by Shh, is similarly expressed. The mutant limb buds are broader than normal buds, and fibroblast growth factor Fgf-8 is expressed throughout the extended ridge. However, expression of the homeobox gene Msx-1, which has been shown to be involved in epithelial-mesenchymal interactions during limb development, was decreased in the mesenchyme of BMP-7 mutant limbs. Taken together, our data suggest that BMP-7 is involved in regulating proliferation and/or epithelial-mesenchymal interactions in the developing limb. [less ▲]

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See detailSelegiline stimulates biosynthesis of cytokines interleukin-1 beta and interleukin-6.
Wilfried, K.; Muller, T.; Krüger, Rejko UL et al

in Neuroreport (1996), 7(18), 2847-8

Several lines of evidence indicate an immune-mediated pathophysiology of Parkinson's disease (PD) and Alzheimer's disease (AD). In clinical studies the monoamine oxidase-B inhibitor Selegiline appears to ... [more ▼]

Several lines of evidence indicate an immune-mediated pathophysiology of Parkinson's disease (PD) and Alzheimer's disease (AD). In clinical studies the monoamine oxidase-B inhibitor Selegiline appears to slow the progression of neurological deficits in PD and the cognitive decline in AD. The immune response to bacterial or viral infection and in chronic inflammatory processes is stimulated by an increased synthesis of the cytokines interleukin-1 beta (IL-1 beta) and subsequently interleukin-6 (IL-6). We investigated the influence of Selegiline on the synthesis of IL-1 beta and IL-6 in peripheral blood mononuclear cells (PBMC) from healthy blood donors cultured with or without Selegiline (10(-8)M, 10(-9)M or 10(-10)M) in a humidified atmosphere (7% CO2). Treatment of cultured PBMC with Selegiline significantly increased synthesis of both cytokines. The effect of Selegiline on cytokine biosynthesis may contribute to its putative neuroprotective properties. [less ▲]

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See detailGeneCrunch and Europort, examples for Hierarchical Supercomputing at Silicon Graphics
Schneider, Reinhard UL; Schlenkrich, M.

in WWW-publication (1996)

The SGI POWER CHALLENGEarray TM represents a hierarchical supercomputer because it combines distributed and shared memory technology. We present two projects, Europort and GeneCrunch, that took advantage ... [more ▼]

The SGI POWER CHALLENGEarray TM represents a hierarchical supercomputer because it combines distributed and shared memory technology. We present two projects, Europort and GeneCrunch, that took advantage of such a configuration. In Europort we performed scalability demonstrations up to 64 processors with applications relevant to the chemical and pharmaceutical industries. GeneCrunch, a project in bioinformatics, performed an analysis of the whole yeast genome using the software system GeneQuiz. This project showcased the future demands of HPC in pharmaceutical industries in tackling analysis of fast growing volumes of sequence information. GeneQuiz, an automated software system for large-scale genome analysis developed at the EMBL /EBI , aims at predicting the function of new genes by using an automated, rigorous, rule-based system to process the results of sequence analysis and database searches to build databases of annotations and predictions. In GeneCrunch more than 6,000 proteins from baker's yeast, for which the complete genomic sequence was completed in 1996, were analyzed on a SGI® POWER CHALLENGEarray with 64 processors (R8000® at 90MHz) in three days rather than the seven months predicted for a normal workstation [less ▲]

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See detailZur Eingliederung von Nomen instrumenti im Ripuarischen
Sieburg, Heinz UL

in Germanistik. Publications du Centre Universitaire du Luxembourg. Lettres Allemandes (1996)

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See detailSur une conjecture sur les points de torsion rationnels des Jacobiennes de courbes
Leprévost, Franck UL

in Journal für die Reine und Angewandte Mathematik (1996), 473

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See detailFermionic anomalies in quantum-mechanical relativistic problems
del Sol Mesa, Antonio UL

in Il Nuovo Cimento (1996)

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See detailA Restriction Theorem for Ideals in the Schwartz Algebra of a Nilpotent Lie Group
Ludwig, Jean; Molitor-Braun, Carine UL

in Archiv der Mathematik [=ADM] (1996), 67(3), 199-210

Detailed reference viewed: 101 (0 UL)
See detailJugend und Politik
Willems, Helmut UL; Gille, Martina

in Jugendhilfe Report (1996), (2), 35-35

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See detailPropagation Delay Estimation in Asynchronous Direct-Sequence Code-Division Multiple Access Systems
Ström, Erik G.; Parkvall, Stefan; Miller, Scott L. et al

in IEEE Transactions on Communications (1996), 44(1), 8493

Detailed reference viewed: 37 (0 UL)
See detailDie Polizei im Umgang mit Fremden - Problemlagen, Belastungssituationen und Übergriffe
Bornewasser, Manfred; Eckert, Roland; Willems, Helmut UL

in Fremdenfeindlichkeit in der Polizei? Schriftenreihe der Polizei-Führungsakademie (1996), (1/2), 9-165

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See detailComparison of recent ocean tide models using ground-based tidal gravity measurements
Melchior, Paul; Francis, Olivier UL

in Marine Geodesy (1996), 19(4), 291-330

Detailed reference viewed: 108 (3 UL)
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See detailLa convertibilité des monnaies en Afrique Subsaharienne hors zone franc
Bourgain, Arnaud UL

in Mondes en Développement (1996), 24(94), 71-84

Detailed reference viewed: 69 (2 UL)
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See detailThe Evil of Superefficiency
Stoica, Petre; Ottersten, Björn UL

in Signal Processing (1996), 55(1), 133136

Detailed reference viewed: 29 (0 UL)
See detailReview article of John E. Tiles, John Dewey.
Biesta, Gert UL

in Studies in Philosophy and Education (1996), 15

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See detailMHC-genotyping of IDDM patients in Luxembourg. Evidence for a pediatric patient subgroup.
Hentges, F. R.; Michel, G. H.; Hoffmann, A. J. et al

in Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg (1996), 133(1), 5-12

[No abstract available]

Detailed reference viewed: 67 (0 UL)
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See detail[Beta blockers in chronic heart failure. Clinical position on the topic].
Dominiak, P.; Erdmann, E.; Kreuzer, H. et al

in Der Internist (1996), 37(12), 1274-81279

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See detailTidal Gravity Measurements in Southeast Asia
Melchior, Paul; Francis, Olivier UL; Ducarme, Bernard

in Marées Terrestres Bulletin d'Informations (1996), (125), 9493-9507

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See detailDagmar Schifferli: Anna Pestalozzi-Schulthess. Ihr Leben mit Heinrich Pestalozzi.
Tröhler, Daniel UL

in Bulletin der Schweizerischen Gesellschaft für die Erforschung des 18. Jahrhunderts (1996), 9

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See detailOn some solutions of the Dirac equation
del Sol Mesa, Antonio UL

in Journal of Physics: A Mathematical and General (1996)

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See detailInternal Finance and Capital Accumulation in a Dynamic General Equilibrium Model with Credit Constraints
Sneessens, Henri UL; Stefani, Maria Lucia

in Louvain Economic Review - Recherches Economiques de Louvain (1996), 62(2-3), 255-86

Detailed reference viewed: 40 (1 UL)
See detailBespreking van S. Roegholt. Meerperspectivisch Onderwijs.
Biesta, Gert UL

in Comenius (1996), 16

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See detailApproximate spectral functions in thermal field theory
Henning, P. A.; Polyatchenko, E.; Schilling, Tanja UL et al

in Physical Review. D, Particles and Fields (1996), 54(5239), 1-5

Causality requires that the ~anti!commutator of two interacting field operators vanishes for spacelike coordinate differences. This implies that the Fourier transform of the spectral function of this ... [more ▼]

Causality requires that the ~anti!commutator of two interacting field operators vanishes for spacelike coordinate differences. This implies that the Fourier transform of the spectral function of this quantum field should vanish in the spacelike domain. We find that this requirement imposes some constraints on the use of resummed propagators in high temperature gauge theory. [less ▲]

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See detailBespreking van Max Velthuis, Kikker is verliefd.
Biesta, Gert UL

in Comenius (1996), 16

Detailed reference viewed: 63 (0 UL)
See detailHauptströmungen und Tendenzen der Schweizer Pestalozzi-Forschung
Tröhler, Daniel UL

in Pädagogische Rundschau (1996), 50(1), 59-74

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See detailPAX genes and human neural tube defects: an amino acid substitution in PAX1 in a patient with spina bifida.
Hol, F. A.; Geurds, M. P.; Chatkupt, S. et al

in Journal of Medical Genetics (1996), 33(8), 655-60

From studies in the mouse and from the clinical and molecular analysis of patients with type 1 Waardenburg syndrome, particular members of the PAX gene family are suspected factors in the aetiology of ... [more ▼]

From studies in the mouse and from the clinical and molecular analysis of patients with type 1 Waardenburg syndrome, particular members of the PAX gene family are suspected factors in the aetiology of human neural tube defects (NTD). To investigate the role of PAX1, PAX3, PAX7, and PAX9, allelic association studies were performed in 79 sporadic and 38 familial NTD patients from the Dutch population. Sequence variation was studied by SSC analysis of the paired domain regions of the PAX1, PAX7, and PAX9 genes and of the complete PAX3 gene. In one patient with spina bifida, a mutation in the PAX1 gene was detected changing the conserved amino acid Gln to His at position 42 in the paired domain of the protein. The mutation was inherited through the maternal line from the unaffected grandmother and was not detected in 300 controls. In the PAX3 gene, variation was detected at several sites including a Thr/Lys amino acid substitution in exon 6. All alleles were present among patients and controls in about the same frequencies. However, an increased frequency of the rare allele of a silent polymorphism in exon 2 was found in NTD patients, but no significant association was observed (p = 0.06). No sequence variation was observed in the paired domain of the PAX7 and PAX9 genes. Our findings so far do not support a major role of the PAX genes examined in the aetiology of NTD. However, the detection of a mutation in PAX1 suggests that, in principle, this gene can act as a risk factor for human NTD. [less ▲]

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See detailPax genes and sclerotome induction
Balling, Rudi UL; Neubüser, A; Christ, B

in Seminars in Cell and Developmental Biology (1996), (7), 129-136

Detailed reference viewed: 53 (3 UL)
See detailDer Reminiszenzfragebogen: Skalenkonstruktion und teststatistische Überprüfung.
Mayer, Anne-Kathrin; Filipp, Sigrun-Heide; Ferring, Dieter UL

in Focus Diagnostica (1996), 42(2)

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See detailMaximum Likelihood Array Processing for Stochastic Coherent Sources
Stoica, Petre; Ottersten, Björn UL; Viberg, Mats et al

in IEEE Transactions on Signal Processing (1996), 44

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See detailDesign and analysis of dynamic leader election protocols in broadcast networks
Brunekreef, J. J.; Katoen, J.-P.; Koymans, R. et al

in Distributed Computing (1996), 9(4), 157-171

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