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See detailHet is zoals het is en als ik kan helpen graag: Ervaringen van broers en zussen van kinderen met een lichamelijke handicap
Pit-Ten Cate, Ineke UL; Loots, G.M.P.

in Nederlands Tijdschrift voor Kinderrevalidatie (1998), (2), 33-37

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See detailPicture or word superiority effects in implicit memory: levels of processing, attention and retrieval constraints
Wippich, Werner; Melzer, André UL; Mecklenbräuker, Silvia

in Swiss Journal of Psychology = Schweizerische Zeitschrift für Psychologie = Revue suisse de psychologie (1998), 51(1), 33-46

Previous research with implicit memory tests has shown that the typical picture superiority effect with explicit memory instructions can he reversed on verbal perceptual tests (e.g., word-stem completion ... [more ▼]

Previous research with implicit memory tests has shown that the typical picture superiority effect with explicit memory instructions can he reversed on verbal perceptual tests (e.g., word-stem completion task). Two experiments explored whether the picture superiority effect can be restored with a verbal conceptual test of implicit memory (i.e., category instance generation task). In the first experiment, participants received either a perceptual test or a conceptual test of implicit memory. Furthermore, in the study phase level of processing was varied. With a superficial orienting task, a word superiority effect was found on the perceptual test and a picture superiority effect was observed on the conceptual test. Only with a semantic orienting task, priming was found for pictures on the perceptual test and for words on the conceptual test. In the second experiment, this pattern of findings was replicated with a superficial orienting task in the study phase. Once again priming for pictures on the perceptual test and priming for words on the conceptual test was found to be at chance level. Dividing attention in the study phase did not influence these results. [less ▲]

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See detailBildung und Arbeit: zwei kompatible Begriffe?
Tröhler, Daniel UL

in Panorama (1998), (4), 20-21

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See detailA locus for radiation-induced gastroschisis on mouse Chromosome 7.
Hillebrandt, S.; Streffer, C.; Montagutelli, X. et al

in Mammalian Genome (1998), 9(12), 995-7

Gastroschisis (abdominal wall defects) occurs with a high frequency in the mouse inbred strain HLG compared with C57BL/6J mice. The risk of gastroschisis increases significantly after exposure to ... [more ▼]

Gastroschisis (abdominal wall defects) occurs with a high frequency in the mouse inbred strain HLG compared with C57BL/6J mice. The risk of gastroschisis increases significantly after exposure to irradiation with X-rays during preimplantation development and follows a recessive mode of inheritance for the HLG susceptibility alleles. We have used a backcross strategy and genome-wide microsatellite typing to chromosomally map this trait. A suggestive linkage for a locus responsible for radiation-induced gastroschisis (Rigs1) was found in a region of mouse Chromosome 7. [less ▲]

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See detail«Pijn als een passie bij Antonin Artaud»
Roelens, Nathalie UL

in Streven (1998)

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See detailFast Multiplication on Elliptic Curves over Small Fields of Characteristic Two
Müller, Volker UL

in Journal of Cryptology (1998), 11(4), 219-234

The paper shows how Frobenius expansions can be used to speed up mul­tiplication of points on elliptic curves that are defined over very small fields of charac­teristic two. The Frobenius expansion ... [more ▼]

The paper shows how Frobenius expansions can be used to speed up mul­tiplication of points on elliptic curves that are defined over very small fields of charac­teristic two. The Frobenius expansion algorithm is analyzed in theory and in practice. It can gain significant improvements in practical applica­tions. These curves are there­fore especially interesting for implementations of elliptic curve cryptosystems. [less ▲]

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See detailEinstellungen junger Deutscher gegenüber ausländischen Mitbürgern und ihre Bedeutung hinsichtlich politischer Orientierungen. Ausgewählte Ergebnisse des DJI-Jugendsurvey 1997
Kleinert, Corinna; Krüger, Winfried; Willems, Helmut UL

in Aus Politik und Zeitgeschichte (1998), 48.2(31), 14-27

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See detailEvaluation of the information processing and mood effects of a transdermal nicotine patch.
Warburton, D. M.; Mancuso, Giovanna UL

in Psychopharmacology (1998), 135(3), 305-10

The purpose of this study was to determine whether a transdermal nicotine patch will produce the same effects on performance and mood as cigarette smoking. The nicotine patch improved attentional ... [more ▼]

The purpose of this study was to determine whether a transdermal nicotine patch will produce the same effects on performance and mood as cigarette smoking. The nicotine patch improved attentional processing and produced some improvements in memory. It produced the calming effects of smoking and induced feelings of happiness which were increased with smoking. These effects were obtained 6 h after application of the patch, showing that acute tolerance for these behavioural effects had not developed completely, if at all, after exposure to nicotine, although it is still possible that tolerance might occur with longer exposure. [less ▲]

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See detailParameter Estimation Using a Sensor Array in a Ricean Fading Channel
Hari, K. V. S.; Ottersten, Björn UL

in Signal Processing and Communications (1998), 23

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See detailPedagogy without humanism. Foucault and the subject of education.
Biesta, Gert UL

in Interchange (1998), 29(1), 1-16

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See detailFamilial risk of type 1 diabetes in European children
De Beaufort, Carine UL

in Diabetologia (1998), 41

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See detailLes composantes de l'intelligence générale du D70
Dickes, Paul; Martin, Romain UL

in Psychologie et Psychométrie (1998), 19(1), 27-51

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See detailVon Kleve bis Süchteln - vom Mittelalter bis zur Gegenwart
Heimböckel, Dieter UL

in Zeitschrift der Duisburger Universitäts-Gesellschaft (1998), 50(2), 45

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See detailDer Verkehr als Gegenstand raumbezogener Forschung. Theoretische Überlegungen zur Bedeutung der Transport- und Transaktionskosten.
FLÄMIG, Heike; Hesse, Markus UL

in Geographische Zeitschrift (1998), 86(4), 225-235

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See detailJugend in der DDR. FDJ-Mitgliedschaft und Systemverbundenheit Jugendlicher in den Jahren 1970 bis 1989. Sozialisation und Entwicklung in den neuen Bundesländern. Ergebnisse empirischer Längsschnittforschung.
Bien, Walter; Bischoff, Peter; Willems, Helmut UL

in Zeitschrift für Soziologie der Erziehung und Sozialisation = Journal for Sociology of Education and Socialization (1998)

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See detailThe SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor.
Pusch, C.; Hustert, E.; Pfeifer, D. et al

in Human Genetics (1998), 103(2), 115-23

The SOX genes form a gene family related by homology to the high-mobility group (HMG) box region of the testis-determining gene SRY. We have cloned and sequenced the SOX10 and Sox10 genes from human and ... [more ▼]

The SOX genes form a gene family related by homology to the high-mobility group (HMG) box region of the testis-determining gene SRY. We have cloned and sequenced the SOX10 and Sox10 genes from human and mouse, respectively. Both genes encode proteins of 466 amino acids with 98% sequence identity. Significant expression of the 2.9-kb human SOX10 mRNA is observed in fetal brain and in adult brain, heart, small intestine and colon. Strong expression of Sox10 occurs throughout the peripheral nervous system during mouse embryonic development. SOX10 shows an overall amino acid sequence identity of 59% to SOX9. Like SOX9, SOX10 has a potent transcription activation domain at its C-terminus and is therefore likely to function as a transcription factor. Whereas SOX9 maps to 17q, a SOX10 cosmid has previously been mapped by us to the region 22q13.1. Mutations in SOX10 have recently been identified as one cause of Waardenburg-Hirschsprung disease in humans, while a Sox10 mutation underlies the mouse mutant Dom, a murine Hirschsprung model. [less ▲]

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See detailExponential actions and maximal D-invariant ideals
Molitor-Braun, Carine UL

in Manuscripta Mathematica (1998), 96(1), 23-35

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See detailPrecommitment in Competing Vertical Chains
Irmen, Andreas UL

in Journal of Economic Surveys (1998), 12(4), 333-59

The design of distribution channels is an important marketing decision since a revision implies costly reorganization. Hence, it makes sense to study strategic motives of alternative distribution devices ... [more ▼]

The design of distribution channels is an important marketing decision since a revision implies costly reorganization. Hence, it makes sense to study strategic motives of alternative distribution devices. A precommitment is a strategic move that affects the other players' expectations on how oneself will behave and thus induces them to choose in one's own favor (Schelling, 1960). How these tactics can be used by firms to favorably influence competition between vertical chains is the topic of the literature reviewed in this survey. Copyright 1998 by Blackwell Publishers Ltd [less ▲]

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See detailGenetic dissection of familial Parkinson's disease.
Riess, O.; Jakes, R.; Krüger, Rejko UL

in Molecular Medicine Today (1998), 4(10), 438-44

In the past few years, the genetic contribution to Parkinson's disease (PD) has gained major attention and has resulted in the identification of the first mutant gene, called alpha-synuclein, involved in ... [more ▼]

In the past few years, the genetic contribution to Parkinson's disease (PD) has gained major attention and has resulted in the identification of the first mutant gene, called alpha-synuclein, involved in the pathogenesis of autosomal-dominant PD. alpha-Synuclein is a major component of Lewy bodies, which are a neuropathological feature of PD. Furthermore, deletions in the parkin gene have been identified as the primary cause in rare forms of autosomal-recessive juvenile PD. The elucidation of polygenic changes in the dopamine pathway, mitochondrial dysfunction, and metabolism of xenobiotics is now technically possible by means of association and genotype studies. The increasing knowledge of the pathogenesis of PD at a molecular level will have important implications for the development of individual therapeutic strategies to prevent disease progression. [less ▲]

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See detailExperimente und Modellierung zur heterogenen und homogenen Verbrennung.
Peters, Bernhard UL; Krebs, L.

in FZKA-Bericht (1998), 6084

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See detailComparative analysis of value concepts: Some methodological remarks
Krolak-Schwerdt, Sabine UL; Schneider, Johann F.

in Universität des Saarlandes: Arbeiten der Fachrichtung Psychologie (1998), 185

This paper shows the usefulness of methods of three-mode factor analysis for cross-cultural compa.risous of value concepts. Data were obtained frotu :100 German and :wo American students, using the ... [more ▼]

This paper shows the usefulness of methods of three-mode factor analysis for cross-cultural compa.risous of value concepts. Data were obtained frotu :100 German and :wo American students, using the Individual and Organizational Values SYM LOG rating form. The comparative structural analyses of the samples made it apparent that the SYM LOG rating forms used did not yield the expected correspom.lcncc to the theoretical three-dimensional value space. Reasons for and r.onsequen . ces of these fit,ulings for further studies in this field are discussed. The methodological approach outlined in this paper eau supplement the criteria llales et al. ( 1987) formulated for adaptation o'f SYM LOG rating items to particular populations and cultural contexts, and provides more adequate procedures for da.ta ana.lysis. [less ▲]

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See detailDewey in Europa. Paradoxen van modernisering in de onderwijsvernieuwing: een case study.
Biesta, Gert UL; Miedema, S.

in Nederlands Tijdschrift voor Opvoeding, Vorming en Onderwijs (1998), 14(6), 336-355

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See detailComments on "Min-Norm Interpretations and Consistency of MUSIC, MODE and ML"
Stoica, Petre; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (1998), 46(8), 22622263

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See detailPartial amplification of the measles virus nucleocapsid gene from stored sera and cerebrospinal fluids for molecular epidemiological studies
Kreis, Stephanie UL; Schoub, B. D.

in Journal of Medical Virology (1998), 56(2), 174-177

The analysis of stored sera for retrospective molecular epidemiological studies provides a powerful tool to investigate strain variation in measles viruses that had circulated up to 20 years ago. For this ... [more ▼]

The analysis of stored sera for retrospective molecular epidemiological studies provides a powerful tool to investigate strain variation in measles viruses that had circulated up to 20 years ago. For this purpose, a rapid and simple method for extraction of RNA from stored sera and cerebrospinal fluids (CSF) was developed. When used on sera and CSFs that have been frozen for as long as 20 years, this method proved to be more efficient than established techniques. The extracted RNA was reverse transcribed into cDNA by using random hexamer primers. The PCR amplification of the 3' terminus of the nucleocapsid gene (N) was divided into two overlapping fragments of 375 and 384 bp length, covering the entire region of interest. This region is thought to have the highest variability within the MV genome and has previously been shown to be suitable for strain characterization. The resulting PCR fragments were sequenced manually by using standard methods without the need of further clean-up steps. [less ▲]

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See detailPax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities.
Peters, H.; Neubuser, A.; Kratochwil, K. et al

in Genes and Development (1998), 12(17), 2735-47

Pax genes have been shown to play important roles in mammalian development and organogenesis. Pax9, a member of this transcription factor family, is expressed in somites, pharyngeal pouches, mesenchyme ... [more ▼]

Pax genes have been shown to play important roles in mammalian development and organogenesis. Pax9, a member of this transcription factor family, is expressed in somites, pharyngeal pouches, mesenchyme involved in craniofacial, tooth, and limb development, as well as other sites during mouse embryogenesis. To analyze its function in vivo, we generated Pax9 deficient mice and show that Pax9 is essential for the development of a variety of organs and skeletal elements. Homozygous Pax9-mutant mice die shortly after birth, most likely as a consequence of a cleft secondary palate. They lack a thymus, parathyroid glands, and ultimobranchial bodies, organs which are derived from the pharyngeal pouches. In all limbs, a supernumerary preaxial digit is formed, but the flexor of the hindlimb toes is missing. Furthermore, craniofacial and visceral skeletogenesis is disturbed, and all teeth are absent. In Pax9-deficient embryos tooth development is arrested at the bud stage. At this stage, Pax9 is required for the mesenchymal expression of Bmp4, Msx1, and Lef1, suggesting a role for Pax9 in the establishment of the inductive capacity of the tooth mesenchyme. In summary, our analysis shows that Pax9 is a key regulator during the development of a wide range of organ primordia. [less ▲]

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See detailSelegiline as immunostimulant--a novel mechanism of action?
Muller, T.; Kuhn, W.; Krüger, Rejko UL et al

in Journal of neural transmission. Supplementum (1998), 52

In clinical studies the MAO-B inhibitor selegiline appears to slow the progression of neurological deficits in Parkinson's disease (PD) and the cognitive decline in Alzheimer's disease (AD). The ... [more ▼]

In clinical studies the MAO-B inhibitor selegiline appears to slow the progression of neurological deficits in Parkinson's disease (PD) and the cognitive decline in Alzheimer's disease (AD). The mechanisms of action remain unclear. Several lines of evidence indicate an immune-mediated pathophysiology of PD and AD. According to animal trials, selegiline increases the survival rate of immune suppressed mice. Stimulation of the immune response to bacterial or viral infection or in chronic inflammatory processes in managed by an increased synthesis of the cytokines interleukin-1 beta (IL-1 beta) and subsequent interleukin-6 (IL-6). Outcome of viral or bacterial infections in the brain highly correlates with levels of the cytotoxic cytokine tumor-necrosis-factor-alpha (TNF). The aim of our study was to characterize the influence of selegiline on the biosynthesis of IL-1 beta, IL-6 and TNF in human peripheral blood mononuclear cells (PBMC) from healthy blood donors. After isolation and washing PBMC were cultured without and with selegiline in three different concentrations (0.01 mumol/l, 0.001 mumol/l, 0.0001 mumol/l) in a humidified atmosphere (7% CO2). Then cultures were centrifuged and supernatants were collected for IL-1 beta, IL-6 and TNF ELISA-assays. Treatment of cultured PBMC with various concentrations induced an increased synthesis of IL-1 beta (ANOVA F = 9.703, p = 0.0007), IL-6 (ANOVA F = 20.648, p = 0.0001) and a reduced production of TNF (ANOVA F = 3.770, p = 0.040). These results indicate, that the influence of selegiline on the cytokine biosynthesis may also contribute to its putative neuroprotective properties. [less ▲]

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See detailSugawara construction and Casimir operators for Krichever-Novikov algebras
Schlichenmaier, Martin UL; Sheinman, Oleg K.

in Journal of Mathematical Sciences (1998), 92(2), 3807-3834

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See detailExponential actions, orbits and their kernels
Ludwig, Jean; Molitor-Braun, Carine UL

in Bulletin of the Australian Mathematical Society (1998), 57

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See detailSerum lipid concentrations, hostility, and cardiovascular reactions to mental stress
Vögele, Claus UL

in International Journal of Psychophysiology (1998), 28

The objective of the present study was to determine whether serum lipid concentrations interact with hostility to affect cardiovascular responses to mental stress. One-hundred and seventy-four male ... [more ▼]

The objective of the present study was to determine whether serum lipid concentrations interact with hostility to affect cardiovascular responses to mental stress. One-hundred and seventy-four male subjects were screened with the Cook and Medley hostility scale (Ho), the anger expression inventory by Spielberger and a general health questionnaire. Subjects in the upper (n = 22) and lower (n = 22) quartile of the Ho score distribution were asked to take part in a laboratory experiment. Continuous measures of heart rate, blood pressure, respiration and electrodermal activity were taken while participants carried out a series of behavioral maneuvres, including mental arithmetic and mirror star tracing. Prior to the experiment fasting blood samples were taken for lipid determinations. The results show higher heart rate reactivity in high hostile than low hostile subjects. High hostile subjects also reported more anger and frustration in response to tasks. Hostility groups differed in lipid levels in that high hostiles had higher triglyceride and VLDL-c concentrations than low hostiles. Cholesterol levels showed an inverse association with cardiovascular reactivity but only in low hostile subjects. No such associations could be found in high hostiles. We conclude that there is partial support for both, the hyperreactivity and the health behavior model linking hostility and cardiovascular disorder. [less ▲]

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See detailNecessary conditions for robust stability of a class of nonlinear systems
Goncalves, Jorge UL; Dahleh, M. A.

in Automatica (1998), 34(6), 705-714

Input-output stability results for feedback systems are developed. Robust stability conditions are presented for nonlinear systems with nonlinear uncertainty defined by some function (with argument equal ... [more ▼]

Input-output stability results for feedback systems are developed. Robust stability conditions are presented for nonlinear systems with nonlinear uncertainty defined by some function (with argument equal to the norm of the input) that bounds its output norm. A sufficient small gain theorem for a class of these systems is known. Here, necessary conditions are presented for the vector space (L- infinity ll . ll infinity). These results capture the conservatism of the small gain theorem as it is applied to systems that do not have linear gain. The theory is also developed for the case of L2 signal norms, indicating some difficulties which make this case less natural than L-infinity. [less ▲]

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See detailSelectively Grown Vertical Si MOS Transistor with Reduced Overlap Capacitances
Klaes, D.; Moers, J.; Tönnesmann, A. et al

in Thin Solid Films (1998), 336(1998), 306-308

Vertical p-MOS transistors with channel length of 130 nm have been fabricated using selective epitaxial growth (SEG) to define the channel region. The vertical layout offers the advantages of achieving ... [more ▼]

Vertical p-MOS transistors with channel length of 130 nm have been fabricated using selective epitaxial growth (SEG) to define the channel region. The vertical layout offers the advantages of achieving short channel lengths and high integration densities while still using optical lithography to define lateral dimensions. Compared to other vertical concepts, this layout has reduced gate to source/drain overlap capacitances which is necessary for high speed applications. The use of SEG instead of blanket epitaxy avoids the deterioration of the Si/SiO2 interface due to reactive ion etching (RIE) and reduces punch-through due to facet growth. First non-optimized p-channel MOSFETs with a 12-nm gate oxide show a transconductance of 90 mS/mm. The cut-off frequencies of this device turned out to be f T = 2.3 GHz and f max = 1.1 GHz. [less ▲]

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See detailLa Constitution de 1848
Ravarani, Georges UL

in Forum für Politik, Gesellschaft und Kultur in Luxemburg (1998), (185), 3034

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See detailCalibration of a superconducting gravimeter by comparison with an absolute gravimeter FG5 in Boulder
Francis, Olivier UL; Niebauer, T. M.; Sasagawa, G. et al

in Geophysical Research Letters (1998), 25(7), 1075-1078

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See detailSpinocerebellar ataxia type 6: genotype and phenotype in German kindreds.
Schols, L.; Krüger, Rejko UL; Amoiridis, G. et al

in Journal of neurology, neurosurgery, and psychiatry (1998), 64(1), 67-73

OBJECTIVE: Spinocerebellar ataxia type 6 (SCA6) is an autosomal dominant cerebellar ataxia (ADCA) of which the mutation causing the disease has recently been characterised as an expanded CAG trinucleotide ... [more ▼]

OBJECTIVE: Spinocerebellar ataxia type 6 (SCA6) is an autosomal dominant cerebellar ataxia (ADCA) of which the mutation causing the disease has recently been characterised as an expanded CAG trinucleotide repeat in the gene coding for the alpha1A-subunit of the voltage dependent calcium channel. The aim was to further characterise the SCA6 phenotype METHODS: The SCA6 mutation was investigated in 69 German families with ADCA and 61 patients with idiopathic sporadic cerebellar ataxia and the CAG repeat length of the expanded allele was correlated with the disease phenotype. RESULTS: Expanded alleles were found in nine of 69 families as well as in four patients with sporadic disease. Disease onset ranged from 30 to 71 years of age and was significantly later than in other forms of ADCA. Age at onset correlated inversely with repeat length. The SCA6 phenotype comprises predominantly cerebellar signs in concordance with isolated cerebellar atrophy on MRI. Non-cerebellar systems were only mildly affected with external ophthalmoplegia, spasticity, peripheral neuropathy, and parkinsonism. Neither these clinical signs nor progression rate correlated with CAG repeat length. CONCLUSIONS: This study provides the first detailed characterisation of the SCA6 phenotype. Clinical features apart from cerebellar signs were highly variable in patients with SCA6. By comparison with SCA1, SCA2, and SCA3 no clinical or electrophysiological finding was specific for SCA6. Therefore, the molecular defect cannot be predicted from clinical investigations. In Germany, SCA6 accounts for about 13% of families with ADCA. However, up to 30% of SCA6 kindreds may be misdiagnosed clinically as sporadic disease due to late manifestation in apparently healthy parents. Genetic testing is therefore recommended for the SCA6 mutation also in patients with putative sporadic ataxia. [less ▲]

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See detailL'autonomie des garanties à première demande, analyse comparative avec les effets de commerce
Prüm, André UL

in Waseda Proceedings of Comparative Law (1998), 2

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See detailRez. zu Ingrid Samel: Einführung in die feministische Sprachwissenschaft
Sieburg, Heinz UL

in Zeitschrift für Deutsche Philologie (1998), 117

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See detailInhibitory action of BMPs on Pax1 expression and on shoulder girdle formation during limb development.
Hofmann, C.; Drossopoulou, G.; McMahon, A. et al

in Developmental Dynamics : An Official Publication of the American Association of Anatomists (1998), 213(2), 199-206

Pax1 expression in vertebrate limb buds is confined to cells in a discrete anterior proximal domain (Timmons et al. [1994] Development 120:2773-2785; Ebensperger et al. [1995] Anat. Embryol. 191:297-310 ... [more ▼]

Pax1 expression in vertebrate limb buds is confined to cells in a discrete anterior proximal domain (Timmons et al. [1994] Development 120:2773-2785; Ebensperger et al. [1995] Anat. Embryol. 191:297-310). In dorsoventral patterning of Drosophila, expression of pox meso, an insect gene with high sequence similarity to Pax1, is repressed by decapentaplegic (dpp) in dorsal mesoderm and, thus, is restricted to a discrete ventral domain (Staehling-Hampton et al. [1994] Nature 372:783-786). In the chick wing, cells expressing a vertebrate homolog of dpp, bone morphogenetic protein 4 (Bmp4), abut the Pax1 domain, suggesting a similar relationship between homologous genes in both vertebrates and invertebrates. Here, we show that two BMPs (BMP4, and BMP2, also highly related to dpp) can repress Pax1 in the developing chick wing. Chick wing bud cells expressing Pax1 give rise to the shoulder girdle. Cells in an equivalent position in the mouse forelimb also express Pax1, and Pax1 mutant mice display shoulder girdle defects. Similarly in chick embryos, girdle defects are produced by treatments with signalling molecules that lead to expression of BMPs, which subsequently reduce Pax1 expression in the limb bud. Recently, BMP4 has been shown to inhibit Pax1 expression in the developing trunk (Monsoro-Burq et al. [1996] Development 122:3607-3616) and Pax9 expression in developing teeth (Neubuser et al. [1997] Cell 90:247-255). Thus, a property of BMPs appears to be to regulate pox meso homologs negatively and, thus, limit their expression domains. [less ▲]

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See detailDistinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling.
Schaffner-Reckinger, Elisabeth UL; Gouon, V.; Melchior, Chantal UL et al

in The Journal of biological chemistry (1998), 273(20), 12623-32

We have investigated the structural requirements of the beta3 integrin subunit cytoplasmic domain necessary for tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin during alphav beta3 ... [more ▼]

We have investigated the structural requirements of the beta3 integrin subunit cytoplasmic domain necessary for tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin during alphav beta3-mediated cell spreading. Using CHO cells transfected with various beta3 mutants, we demonstrate a close correlation between alphav beta3-mediated cell spreading and tyrosine phosphorylation of FAK and paxillin, and highlight a distinct involvement of the NPLY747 and NITY759 motifs in these signaling processes. Deletion of the NITY759 motif alone was sufficient to completely prevent alphav beta3-dependent focal contact formation, cell spreading, and FAK/paxillin phosphorylation. The single Y759A substitution induced a strong inhibitory phenotype, while the more conservative, but still phosphorylation-defective, Y759F mutation restored wild type receptor function. Alanine substitution of the highly conserved Tyr747 completely abolished alphav beta3-dependent formation of focal adhesion plaques, cell spreading, and FAK/paxillin phosphorylation, whereas a Y747F substitution only partially restored these events. As none of these mutations affected receptor-ligand interaction, our results suggest that the structural integrity of the NITY759 motif, rather than the phosphorylation status of Tyr759 is important for beta3-mediated cytoskeleton reorganization and tyrosine phosphorylation of FAK and paxillin, while the presence of Tyr at residue 747 within the NPLY747 motif is required for optimal beta3 post-ligand binding events. [less ▲]

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See detail550 GHz bandwidth photodetector on low-temperature grown molecular-beam epitaxial GaAs
Kordoš, P.; Förster, A.; Marso, Michel UL et al

in Electronics Letters (1998), 34(1998), 119-120

The authors demonstrate that a 550GHz bandwidth photodetector can be fabricated on low-temperature grown MBE GaAs. The pulse response shows 0.4 and 0.6ps rise and fall times, respectively. The bandwidth ... [more ▼]

The authors demonstrate that a 550GHz bandwidth photodetector can be fabricated on low-temperature grown MBE GaAs. The pulse response shows 0.4 and 0.6ps rise and fall times, respectively. The bandwidth is in agreement with a value calculated using a carrier lifetime of 0.2ps, measured by femtosecond time-resolved reflectivity, and a capacitance of 0.014fF/um2, determined from microwave measurements. The device bandwidth is RC limited. [less ▲]

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See detailWhose law for sharing research tools?
Balling, Rudi UL

in Nature (1998), 396(6711), 509

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See detailDeux missions diplomatiques du secrétaire d’État allemand Urbain de Scharenberg en Empire (1560 et 1565/1566)
Weis, Monique UL

in Bulletin de la Commission Royale d'Histoire (1998), 164

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See detailAngiotensin converting enzyme inhibition modulates cardiac fibroblast growth.
Grohe, C.; Kahlert, S.; Lobbert, K. et al

in Journal of hypertension (1998), 16(3), 377-84

BACKGROUND: The progression of left ventricular hypertrophy and cardiac fibrosis in hypertensive heart disease is influenced by sex and age. Although angiotensin converting enzyme inhibition has been ... [more ▼]

BACKGROUND: The progression of left ventricular hypertrophy and cardiac fibrosis in hypertensive heart disease is influenced by sex and age. Although angiotensin converting enzyme inhibition has been shown to prevent progression of the disease in postmenopausal women, the interaction of angiotensin II and estrogen in this process before and after the menopause is poorly understood. OBJECTIVE: To investigate the influence of the angiotensin converting enzyme inhibitor moexiprilat on serum, estrogen and angiotensin II-induced cardiac fibroblast growth. METHODS: Neonatal rat cardiac fibroblasts were incubated with 1 and 10% fetal calf serum, 10(-7) mol/l angiotensin II, 10(-9) mol/l estrone, 10(-9) mol/l 17beta-estradiol and 10(-8) mol/l moexiprilat. Proliferation was measured in terms of incorporation of bromodeoxyuridine. Western blot analysis was performed using antibodies directed against the growth-related immediate early genes c-fos and Sp-1. All experiments were performed at least three times. RESULTS: Fetal calf serum stimulated cardiac fibroblast proliferation (1% fetal calf serum 2.0+/-0.028-fold; 10% fetal calf serum 2.7+/-0.028-fold). Angiotensin II and estrone stimulated proliferation of cardiac fibroblasts grown in the absence of fetal calf serum (angiotensin II 4.2+/-0.075-fold; estrone 2.9+/-0.034-fold) and further increased proliferation in the presence of 1% fetal calf serum (angiotensin 11 4.3+/-0.072-fold); estrone 3.8+/-0.045-fold) and 10% fetal calf serum (angiotensin II 4.8+/-0.112-fold; estrone 4.1+/-0.047-fold). Coincubation with moexiprilat specifically inhibited proliferation induced by angiotensin II and estrone but not by serum, and angiotensin II type 1 receptor blockade inhibited angiotensin II-induced but not estrone-induced cell growth. Western blot analysis showed that the expression of c-fos and Sp-1 was induced in a time-dependent fashion by angiotensin II (to maxima of 5.0-fold for c-fos and 3.0-fold for Sp-1) and estrone (15.2-fold for c-fos and 6.2-fold for Sp-1). This effect was completely inhibited by moexiprilat. CONCLUSIONS: Angiotensin converting enzyme inhibition modulates cardiac fibroblast growth induced by angiotensin II and estrone. This mechanism might contribute to the beneficial effects of angiotensin converting enzyme inhibition in postmenopausal patients with hypertensive heart disease. [less ▲]

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See detailPremier et deuxième espaces de cohomologie de l'algèbre de Lie des opérateurs différentiels sur une variété à coefficients dans les fonctions
Poncin, Norbert UL

in Bulletin de la Société Royale des Sciences de Liège (1998), 67(6), 291--337

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See detailPsychological factors associated with the uptake of measles immunization. Findings and implications for prevention.
Weitkunat, Rolf; Markuzzi, Andreas; Vogel, Susanne et al

in Journal of Health Psychology (1998), 3(2)

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See detailTroisième espace de cohomologie de l'algèbre de Lie des opérateurs différentiels sur une variété à coefficients dans les fonctions
Poncin, Norbert UL

in Bulletin de la Société Royale des Sciences de Liège (1998), 67(6), 339--393

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See detailPax genes and organogenesis: Pax9 meets tooth development.
Peters, H.; Neubuser, A.; Balling, Rudi UL

in European Journal of Oral Sciences (1998), 106 Suppl 1

Pax genes encode a family of transcription factors that play key roles during embryogenesis. They are required for the development of a variety of organs including the nervous and muscular system ... [more ▼]

Pax genes encode a family of transcription factors that play key roles during embryogenesis. They are required for the development of a variety of organs including the nervous and muscular system, skeleton, eye, ear, kidney, thymus, and pancreas. Whereas the developmental roles of many of the nine known Pax genes have been analyzed in great detail, a functional analysis of Pax9 has just begun. During mouse embryogenesis, Pax9 exhibits a highly specific expression pattern in derivatives of the foregut endoderm, somites, limb mesenchyme, midbrain, and the cephalic neural crest. In the mandibular arch mesenchyme, the expression of Pax9 marks the prospective sites of tooth development prior to any morphological signs of odontogenesis and is maintained in the developing tooth mesenchyme thereafter. To understand the function of Pax9 during mouse embryogenesis, we recently have created a null allele by gene targeting. Preliminary analyses show that Pax9 is essential for the formation of teeth, and we conclude that Pax9 is required for tooth development to proceed beyond the bud stage. Here, we briefly summarize our current knowledge about Pax genes and introduce Pax9 to the growing family of factors which are involved in tooth development. [less ▲]

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See detailSome remarks on the heat flow for functions and forms
Thalmaier, Anton UL

in Electronic Communications in Probability (1998), 3

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See detailExamination of colocalization of calcitonin gene-related peptide- and substance P-like immunoreactivity in the knee joint of the dog
Tamura, Ryoko; Hanesch, Ulrike UL; Schmidt, Robert et al

in Neuroscience Letters (1998), 254

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See detailDie kommunale grenzüberschreitende Zusammenarbeit - Basis und Motor der europäischen Integration? Das Beispiel Saar-Lor-Lux.
Schulz, Christian UL

in Berichte zur Deutschen Landeskunde (1998), 1998(4), 267-290

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See detailInternalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway
Thiel, S.; Behrmann, Iris UL; Dittrich, E. et al

in Biochemical Journal (1998), 330 (Pt 1)

Signalling receptors often undergo receptor-mediated endocytosis. In many cases this internalization is stimulated by ligand binding and activation of intrinsic receptor tyrosine kinases, resulting in a ... [more ▼]

Signalling receptors often undergo receptor-mediated endocytosis. In many cases this internalization is stimulated by ligand binding and activation of intrinsic receptor tyrosine kinases, resulting in a receptor down-regulation. We have analysed whether internalization of the interleukin 6 signal transducer gp130 is dependent on the activation of receptor-associated Jak kinases. By using a chimaeric receptor system we found that receptor mutants that lack box1 and therefore are not capable of activating Jak and signal transducer and activator of transcription (STAT) proteins are still endocytosed efficiently. A chimaeric receptor with the recently identified dileucine internalization motif being replaced by two alanine residues was not efficiently internalized but still capable of recruiting STATs. Furthermore an antagonistic antibody that inhibits the signalling of all interleukin-6-type cytokines via gp130 was internalized as efficiently as an agonistic one that activates the Jak/STAT pathway. Our findings suggest that the endocytosis of gp130 is signal-independent. [less ▲]

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See detailEtude de l'algèbre L¹(G,w) avec G groupe de Lie nilpotent et w poids polynomial
Mint Elhacen, Salma; Molitor-Braun, Carine UL

in Travaux Mathématiques (1998), 10

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See detailA detailed analysis of tropospheric effects on geodetic observations at TMGO
Schenewerk, M.; van Dam, Tonie UL; Sasagawa, G. et al

in Physics and chemistry of the earth (1998), 23(1), 103-106

Improvements in geodetic tools are making previously subtle effects significant. Two examples affecting GPS observations are atmospheric loading of the Earth's crust and the tropospheric delays ... [more ▼]

Improvements in geodetic tools are making previously subtle effects significant. Two examples affecting GPS observations are atmospheric loading of the Earth's crust and the tropospheric delays, specifically the wet component. Each measurement, tropospheric delays and site coordinates, requires unambiguous determination of the other to achieve the highest accuracy. Table Mountain Geophysical Observatory (TMGO) is a unique site where a long history of observations from two complementary techniques, GPS and superconducting gravimetry, have been accrued. In particular, the superconducting gravity measurements provide a unique baseline for evaluating GPS vertical estimates over a variety of time frames. Positional estimates for TMGO using these techniques will be compared. Tropospheric effects will be identified and discussed. The ability for GPS to make subdaily, daily, and long term vertical estimates will be evaluated. [less ▲]

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See detailMeer pedagogiek in de lerarenopleiding?
Biesta, Gert UL

in Tijdschrift voor lerarenopleiders (1998), 19(2), 69-74

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See detailAz Európai Közösség büntetőjoga
Ligeti, Katalin UL

in Állam- és Jogtudomány (1998)

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See detailWe need more mutants: Plans for a large scale ENU mouse mutagenesis screen
Balling, Rudi UL; Hrabe de Angelis, M; Schughart, K et al

in OECD Economics Department Working Papers (1998), (98), 103-111

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See detailTime depending Malliavin calculus on manifolds and application to nonlinear filtering
Schiltz, Jang UL

in Probability and Mathematical Statistics (1998), 18(2), 319-334

In this paper, we prove, using Malliavin calculus, that under a global Hormander condition the law of a Riemannian manifold valued stochastic process, a solution of a stochastic differential equation with ... [more ▼]

In this paper, we prove, using Malliavin calculus, that under a global Hormander condition the law of a Riemannian manifold valued stochastic process, a solution of a stochastic differential equation with time dependent coefficients, admits a smooth density with respect to the Riemannian volume element. This result is applied to a nonlinear filtering problem with time dependent coefficients on manifolds. [less ▲]

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See detailDeconstruction, justice and the question of education.
Biesta, Gert UL

in Zeitschrift für Erziehungswissenschaft (1998), 1(3), 395-411

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See detailConduction in nonstoichiometric molecular-beam epitaxial GaAs grown above the critical thickness
Kordoš, P.; Marso, Michel UL; Luysberg, M.

in Applied Physics Letters (1998), 72

Different conduction behavior is observed in nonstoichiometric ~NS! molecular-beam epitaxial GaAs grown at 200 °C below and above the critical thickness. In the low-field Ohmic region only the ... [more ▼]

Different conduction behavior is observed in nonstoichiometric ~NS! molecular-beam epitaxial GaAs grown at 200 °C below and above the critical thickness. In the low-field Ohmic region only the monocrystalline part of the layer contributes to the room-temperature resistivity, but at higher temperatures the resistivity scales with the total layer thickness. In NS GaAs grown above the critical thickness, a superlinear J –V^n (n=2 – 3) dependence is found at intermediate fields. The prebreakdown voltage is proportional to the total thickness. This indicates that different defects control the electrical properties of the polycrystalline and monocrystalline parts of the NS GaAs. These results can be useful in the design of NS GaAs based devices, which operate at higher temperature and/or higher electric fields. [less ▲]

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See detailTeam Approaches to Treating Children with Disabilities: A Comparison
Rosen, Carol; Miller, A. Cate; Pit-Ten Cate, Ineke UL et al

in Archives of Physical Medicine & Rehabilitation (1998), 79(4), 430-434

Objective: To investigate differences in team functioning between the multidisciplinary and transdisciplinary models when treating children with disabilities. Design: A crossover trial. Setting: An ... [more ▼]

Objective: To investigate differences in team functioning between the multidisciplinary and transdisciplinary models when treating children with disabilities. Design: A crossover trial. Setting: An outpatient educational and rehabilitation program in a rehabilitation institute based at a university medical center. Participants: A population-based sample of 19 rehabilitation specialists and educators. Intervention: Participants attended four team meetings using the multidisciplinary approach and then attended four team meetings using the transdisciplinary approach. Outcome Measures: Behavioral ratings of team participation (Transdisciplinary Team Rating Scale) and self-report instruments of team development (Team Assessment Questionnaire) and treatment planning and goal development (Staff Perception Questionnaire). Results: Results of t tests confirmed the hypothesis that there was more team member participation during transdisciplinary meetings than during multidisciplinary meetings (p = .027), There were no differences in levels of team development (p = .329); however, staff members favored the transdisciplinary model for treatment planning and goal development (p < .001). Conclusion: This study provides evidence of the effectiveness of the transdisciplinary model. Further research is now needed to investigate outcome variables such as rate of success in attaining treatment goals when using this model. [less ▲]

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See detailLa représentation en justice des personnes morales de droit public, note sous Cour administrative 15 janvier 1998
Ravarani, Georges UL

in Pasicrisie Luxembourgeoise: Recueil Trimestriel de la Jurisprudence Luxembourgeoise (1998), 30

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See detailRelating factor matrices of different dimensionality: A note on optimizing orthogonal procrustes solutions
Krolak-Schwerdt, Sabine UL; Orlik, Peter

in Universität des Saarlandes: Arbeiten der Fachrichtung Psychologie (1998), 187

l'vlatching by the Procrustes method involves the transformation of a matrix A to maximal agreement with a specified target matrix B. The present paper is concerned with the soluti on of the 'Orthogonal ... [more ▼]

l'vlatching by the Procrustes method involves the transformation of a matrix A to maximal agreement with a specified target matrix B. The present paper is concerned with the soluti on of the 'Orthogonal Procrustes problem' when the column orders of A and B are different. Avai lable techniques ei ther yield nonunique solutious or the column order of one matrix has to be adjusted by truncating or adding some columns. A new method i s advanced which provides a unique sol,ut.ion without constraining the number of columns of corresponding matrices. An illustrative example is given. [less ▲]

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See detail„Still stable after all this ...=“: Temporal comparison in coping with severe and chronic disease.
Klauer, Thomas; Ferring, Dieter UL; Filipp, Sigrun-Heide

in International Journal of Behavioral Development (1998), 22(2)

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See detailAla30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
Krüger, Rejko UL; Kuhn, W.; Muller, T. et al

in Nature genetics (1998), 18(2), 106-8

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See detailPanorama de jurisprudence en matière d'indemnisation du dommage, 1e mise à jour
Ravarani, Georges UL

in Pasicrisie Luxembourgeoise: Recueil Trimestriel de la Jurisprudence Luxembourgeoise (1998), 30

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See detailCardiovascular effects of Org 9487 under isoflurane anaesthesia in man
Osmer, Christian; Wulf, Kay; Vögele, Claus UL et al

in European Journal of Anaesthesiology (1998), (15), 585-589

The cardiovascular effects of Org 9487 during isoflurane anaesthesia have been evaluated using three doses around its ED90 for neuromuscular blockade, i.e. 1 mg kg-1, 2 mg kg-1 and 3 mg kg-1. Heart rate ... [more ▼]

The cardiovascular effects of Org 9487 during isoflurane anaesthesia have been evaluated using three doses around its ED90 for neuromuscular blockade, i.e. 1 mg kg-1, 2 mg kg-1 and 3 mg kg-1. Heart rate increased to 110%, 115% and 118% in patients receiving 1 mg kg-1, 2 mg kg-1 and 3 mg kg-1 respectively. There were no significant effects on systolic and diastolic blood pressures for the two lower dose groups. Patients receiving Org 9487 3 mg kg-1 displayed significant decreases in systolic and diastolic blood pressures (91% and 82% of the control values respectively). Except for heart rate in the group receiving 3 mg kg-1, all measurements returned to baseline after a maximum of 15 min. Six patients experienced a transient increase in airway pressure after administration of Org 9487, which was accompanied by a decrease in oxygen saturation in two out of six subjects, but there was no audible wheezing. These episodes were self-limiting and required no treatment. There were no other adverse reactions to this drug during this study. [less ▲]

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See detailVirtual Convergence and Dialect Levelling in Luxemburgish
Gilles, Peter UL

in Folia Linguistica (1998), 32(1-2), 69-82

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See detailLarge scale ENU screens in the mouse: genetics meets genomics.
Hrabe de Angelis, M.; Balling, Rudi UL

in Mutation research (1998), 400(1-2), 25-32

The worldwide effort to completely sequence the human and mouse genome will be accomplished within the next years. The focus of current activities within the framework of human genome research is mainly ... [more ▼]

The worldwide effort to completely sequence the human and mouse genome will be accomplished within the next years. The focus of current activities within the framework of human genome research is mainly on the assembly of high resolution genetic and physical maps and genomic sequencing. Cloning of new genes is getting more easy using those maps. Nevertheless, it is necessary to work on a systematic analysis of gene function. Results obtained from these efforts will be of enormous value for future biological and biomedical research. However, even the complete sequence will not in all cases reveal the molecular and cellular role of the different genes. Therefore, the next phase of the Human Genome Project will have at its core the functional analysis of genes. Those genes relevant for the diagnosis, prevention and therapy of human diseases are of particular interest. Looking at the history of life sciences, mutants have been the most important tool to obtain insight into the biological function of genes. The mouse is the model of choice for the study of inherited diseases in man. In order to meet the requirements for functional human genome analysis, we need a large number of mouse mutants similar to the collection of mutants available for other model organisms such as flys and worms. To fully apply the power of genetics, multiple alleles of the same gene such as hypomorphs or hypermorphs are required. Efficient production of mouse mutants showing specific phenotypes can be achieved by the use of ethylnitrosourea (ENU). ENU is the most powerful mutagen known and we currently see a renaissance of ENU mutagenesis. The application of ENU mutagenesis is reviewed and discussed in the context of a new era of functional genomics. [less ▲]

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See detailJean de Luxembourg, prince idéal et chevalier parfait. Aux origines d'un mythe
Margue, Michel UL

in Mediaevalia Historica Bohemica (1998), 5

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See detailWeighted Subspace Fitting for General Array Error Models
Jansson, Magnus; Swindlehurst, A. Lee; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (1998), 46(9), 24842498

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See detailTargeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency.
Wilm, B.; Dahl, E.; Peters, H. et al

in Proceedings of the National Academy of Sciences of the United States of America (1998), 95(15), 8692-7

The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants, the ... [more ▼]

The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants, the undulated alleles, exhibit phenotypes of different severity in these skeletal elements. Nevertheless, these analyses have not clarified whether the semidominant Undulated short-tail (Uns) mutation, in which the complete Pax1 locus is deleted, represents a null allele. Moreover, the analyses of the classical undulated mutants did not allow a conclusion with respect to haploinsufficiency of Pax1. To address both questions we have created a Pax1 null allele in mice by gene targeting. Surprisingly, the phenotype of this defined mutation exhibits clear differences to that of Uns. This result strongly indicates the contribution of additional gene(s) to the Uns mutant phenotype. Furthermore, the phenotype of mice heterozygous for the null allele demonstrates that Pax1 is haploinsufficient in some though not all skeletal elements which express Pax1 during embryonic development. [less ▲]

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See detailCompetition in Multi-characteristics Spaces: Hotelling Was Almost Right
Irmen, Andreas UL; Thisse, Jacques-Francois

in Journal of Economic Theory (1998), 78(1), 76-102

Lancasterian models of product differentiation typically assume a one-dimension characteristics space. We show that standard results on prices and locations no longer hold when firms compete in a multi ... [more ▼]

Lancasterian models of product differentiation typically assume a one-dimension characteristics space. We show that standard results on prices and locations no longer hold when firms compete in a multi- characteistics space. [less ▲]

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See detailLes transferts de données personnelles vers des pays tiers au regard de la directive européenne relative à la protection des personnes physiques à l'égard du traitement des données à caractère personnel et à la libre circulation des ces données (directive 95/46/CE du 24 octobre 1995)
Prüm, André UL

in Waseda Proceedings of Comparative Law (1998), 2

Les transferts de données personnelles vers des pays tiers au regard de la directive européenne relative à la protection des personnes physiques à l'égard du traitement des données à caractère personnel ... [more ▼]

Les transferts de données personnelles vers des pays tiers au regard de la directive européenne relative à la protection des personnes physiques à l'égard du traitement des données à caractère personnel et à la libre circulation des ces données (directive 95/46/CE du 24 octobre 1995) [less ▲]

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See detailStädtischer Wirtschaftsverkehr als Gegenstand der kommunalen Planung. Möglichkeiten und Grenzen privat-öffentlicher Kooperation.
Hesse, Markus UL

in Archiv für Kommunalwissenschaften (1998), II

Der Beitrag skizziert aktuelle Tendenzen im System der Logistik und ihre Bedeutung für die Stadtentwicklung. Ein besonderes Augenmerk liegt auf dem Handlungsrahmen der Stadtplanung, mit ihren ... [more ▼]

Der Beitrag skizziert aktuelle Tendenzen im System der Logistik und ihre Bedeutung für die Stadtentwicklung. Ein besonderes Augenmerk liegt auf dem Handlungsrahmen der Stadtplanung, mit ihren Rechtsetzungen und Strategien Leitplanken für eine stadtverträgliche Logistik zu setzen. [less ▲]

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See detailStadtentwicklung im Zeichen von "Auflösung" und Nachhaltigkeit.
Hesse, Markus UL; Schmitz, Stefan

in Informationen zur Raumentwicklung (1998), 7/8

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See detailTwo years of continuous measurements of tidal and nontidal variations of gravity in Boulder, Colorado
van Dam, Tonie UL; Francis, Olivier UL

in Geophysical Research Letters (1998), 25(3), 393-396

We report here on the results of an analysis of 2 years of data from NOAA’s superconducting gravimeter located at the Table Mountain Gravity Observatory in Boulder, Colorado. Observed tidal parameters ... [more ▼]

We report here on the results of an analysis of 2 years of data from NOAA’s superconducting gravimeter located at the Table Mountain Gravity Observatory in Boulder, Colorado. Observed tidal parameters, corrected for ocean loading effects, are compared with theoretical tidal parameters predicted for a non-hydrostatic inelastic Earth model and demonstrate excellent agreement. Tidal residuals, corrected for polar motion and a linear instrument drift are highly correlated with gravity changes measured by two absolute gravimeters over the same time period. The admittance to local pressure i s found to be -0.356 mGal/mbar. However, this admittance factor is found to be seasonally and frequency dependent. Correlations between rainfall events and gravity changes are observed. Attempts to model these gravity changes as exponential functions of time were unsuccessful. [less ▲]

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See detailDiscrete Logarithm Based Cryptosystems in Quadratic Function Fields of Charac­teristic 2
Müller, Volker UL; Vanstone, Scott; Zuccherato, Robert

in Designs, Codes and Cryptography (1998), 14(2), 159-178

We describe a public key cryptosystem which works in quadratic function fields of characteristic two. Formulas for arithmetic are explicitly giv­en. The security of the system is based on the discrete ... [more ▼]

We describe a public key cryptosystem which works in quadratic function fields of characteristic two. Formulas for arithmetic are explicitly giv­en. The security of the system is based on the discrete logarithm problem in these fields. Therefore we also describe a Discrete Logarithm algorithm based on the ideas of Pohlig and Hell­man, especially adopted to quadratic function fields of charac­teristic two. [less ▲]

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See detailGeneralized Morse potential: Symmetry and satellite potentials
del Sol Mesa, Antonio UL

in Journal of Physics: A Mathematical and General (1998)

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See detailGradient estimates for harmonic functions on regular domains in Riemannian manifolds
Thalmaier, Anton UL; Wang, Feng-Yu

in Journal of Functional Analysis (1998), 155(1), 109-124

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See detailKonflikte zwischen den Generationen im Erwachsenenalter: Daten zu Verbreitung und Manifestationsformen aus einer Repräsentativerhebung
Filipp, Sigrun-Heide; Boll, Thomas UL

in Psychologische Beiträge : Vierteljahresschrift für alle Gebiete der Psychologie (1998), 40(3/4), 235-253

The prevalence of inter- and intragenerational conflicts is assessed in a large sample of the middle-aged and old-aged German population. N = 4017 adult subjects ranging in age from 40 to 85 years ... [more ▼]

The prevalence of inter- and intragenerational conflicts is assessed in a large sample of the middle-aged and old-aged German population. N = 4017 adult subjects ranging in age from 40 to 85 years indicated current personal conflicts with regard to the relative age of conflict partners (e.g., younger, older, same age), intra- vs. extrafamilial location of conflict, and conflict behaviour. More than ten percent of the subjects reported current intergenerational conflicts, involving family members more often than persons not belonging to one’s family. The prevalence of intergenerational conflicts increased and prevalence of intragenerational conflicts decreased with respondents’ age. Women were more frequently engaged in conflicts with older persons, especially family members. Results are discussed with respect to underlying processes that could mediate the covariation between sociodemographic variables and frequency of intergenerational conflicts. A strategy for further research on intergenerational conflicts is sketched. [less ▲]

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See detailOn nonstrict means
Fodor, János; Marichal, Jean-Luc UL

in Aequationes Mathematicae (1997), 54(3), 308-327

The general form of continuous, symmetric, increasing, idempotent solutions of the bisymmetry equation is established and the family of sequences of functions which are continuous, symmetric, increasing ... [more ▼]

The general form of continuous, symmetric, increasing, idempotent solutions of the bisymmetry equation is established and the family of sequences of functions which are continuous, symmetric, increasing, idempotent, decomposable is described. [less ▲]

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See detailThe pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin: Nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus.
König, Ariane UL; Schwecke, T.; Molnár, I. et al

in European Journal of Biochemistry (1997), 247(2), 526-534

An open reading frame (rapP) encoding the putative pipecolate-incorporating enzyme (PIE) has been identified in the gene cluster for the biosynthesis of rapamycin in Streptomyces hygroscopicus. Conserved ... [more ▼]

An open reading frame (rapP) encoding the putative pipecolate-incorporating enzyme (PIE) has been identified in the gene cluster for the biosynthesis of rapamycin in Streptomyces hygroscopicus. Conserved amino acid sequence motifs for ATP binding, ATP hydrolysis, adenylate formation, and 4'-phosphopantetheine attachment were identified by sequence comparison with authentic peptide synthetases. Disruption of rapP by phage insertion abolished rapamycin production in S. hygroscopicus, and the production of the antibiotic was specifically restored upon loss of the inserted phage by a second recombination event. rapP was expressed in both Escherichia coli and Streptomyces coelicolor, and recombinant PIE was purified to homogeneity from both hosts. Although low-level incorporation of [14C]beta-alanine into recombinant PIE isolated from E. coli was detected, formation of the covalent acylenzyme intermediate could only be shown with the PIE from S. coelicolor, suggesting that while the recombinant PIE from S. coelicolor was phosphopantetheinylated, only a minor proportion of the recombinant enzyme from E. coli was post-translationally modified. [less ▲]

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See detailCarte blanche - L"affaire Clabecq : légalisme contre légitimité ?
Corbisier, Isabelle UL

in Information & Documentation Juridiques (1997)

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See detailPredictions of crustal deformation and of geoid and sea level variability caused by oceanic at atmospheric loading
van Dam, Tonie UL; Wahr, J.; Chao, Y. et al

in Geophysical Journal International (1997), 129(3), 507-517

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See detailSequence analysis of the nucleocapsid gene of measles virus isolates from South Africa identifies a new genotype
Kreis, Stephanie UL; Vardas, E.; Whistler, T.

in Journal of General Virology (1997), 78(7), 1581-1587

Sequence analysis was performed on 20 measles virus (MV) isolates from South Africa, five of which were obtained between 1986 and 1989 and 15 isolates collected during the 1994/95 measles season. A 590 bp ... [more ▼]

Sequence analysis was performed on 20 measles virus (MV) isolates from South Africa, five of which were obtained between 1986 and 1989 and 15 isolates collected during the 1994/95 measles season. A 590 bp fragment of the carboxyl terminus of the nucleocapsid (N) was amplified by PCR and subjected to sequence and phylogenetic analysis. Comparison of the South African MV strains with those previously described revealed that at least two distinct groups of wild-type (wt) MV exist, one of which has been circulating since 1986. The major genotype (I) was represented by the more recent isolates which showed three characteristic amino acid substitutions. Furthermore, three vaccine-like viruses with sequences very similar to the Edmonston wt strain were identified. Phylogenetic analysis of 100 MV strains allowed the assignment of new definitions for MV genotypes and subgroups. Employing these definitions, the majority of South African isolates analysed here formed a new genotype. [less ▲]

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See detailFiltrage de diffusions faiblement bruitées dans le cas corrélé
Schiltz, Jang UL

in Comptes Rendus de l'Académie des Sciences. Série I. Mathématique (1997), 325

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See detailAlgorithms For Phylogeny Reconstruction In a New Mathematical Model
Lenzini, Gabriele UL; Marianelli, Silvia

in Calcolo (1997), 1-4(34), 1-24

The evolutionary history of a set of species is represented by a tree called phylogenetic tree or phylogeny. Its structure depends on precise biological assumptions about the evolution of species ... [more ▼]

The evolutionary history of a set of species is represented by a tree called phylogenetic tree or phylogeny. Its structure depends on precise biological assumptions about the evolution of species. Problems related to phylogeny reconstruction (i.e., finding a tree representation of information regarding a set of items) are widely studied in computer science. Most of these problems have found to be NP-hard. Sometimes they can solved polynomially if appropriate restrictions on the structure of the tree are fixed. This paper summarizes the most recent problems and results in phylogeny reconstruction, and introduces an innovative tree model, called Phylogenetic Parsimonious Tree, which is justified by significant biological hypothesis. Using PPT two problems are studied: the existence and the reconstruction of a tree both when sequences of characters and partial order on interspecies distances are given. We rove complexity results that confirm the hardness of this class of problems. [less ▲]

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See detailPain, Anxiety, and Cooperativeness in Children with Cerebral Palsy after Rhizotomy: Changes Throughout Rehabilitation
Miller, A. Cate; Johann-Murphy, Marjorie; Pit-Ten Cate, Ineke UL

in Journal of Pediatric Psychology (1997), 22(5), 689-705

Assessed pain, anxiety, physical functioning, and cooperativeness in 32 children with spastic cerebral palsy. This is the first study to assess children throughout rehabilitation following selective ... [more ▼]

Assessed pain, anxiety, physical functioning, and cooperativeness in 32 children with spastic cerebral palsy. This is the first study to assess children throughout rehabilitation following selective posterior rhizotomy. Results of the Observational Scale of Behavioral Distress and observer Liken ratings confirmed the hypothesis that children's pain and anxiety decrease over time. Children's physical functioning and cooperativeness improve over time. No significant correlation was found between pain and changes in physical functioning. Cognitive impairment, parental involvement, and children's pain behaviors explained 77% and 56% of the variance in two forms of cooperativeness. Research and clinical implications are discussed, and special considerations regarding pain assessment and management in this population are addressed. [less ▲]

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See detail« Pierre Klossowski: voyeurisme en theofanie»
Roelens, Nathalie UL

in ALW-Cahier (1997)

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See detailElectrical Behaviour of the InP/InGaAs Based MSM-2DEG Diode
Marso, Michel UL; Horstmann, M.; Hardtdegen, H. et al

in Solid-State Electronics (1997), 41(1997), 25-31

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See detailSubjektives Wohlbefinden im Alter: Struktur- und Stabilitätsanalysen.
Ferring, Dieter UL; Filipp, Sigrun-Heide

in Psychologische Beiträge : Vierteljahresschrift für alle Gebiete der Psychologie (1997), 39(3)

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See detailOrdering problems in fermionic relativistic quantum mechanics
del Sol Mesa, Antonio UL

in International Journal of Modern Physics A (1997)

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