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See detailEmergence of diffusion in finite quantum systems
Esposito, Massimiliano UL; Gaspard, P.

in Physical Review. B (2005), 71(21),

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See detail«Editorial»
Roelens, Nathalie UL

in Voir (2005)

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See detailInfection and Corruption: Cooks and Kitchens in Eighteenth-Century France
Takats, Sean UL; Edwards, Kathryn; Harrison, Carol

in Proceedings of the Western Society for French History (2005), 33

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See detailRegulation of nitrate and nitrite respiration in γ-proteobacteria: a comparative genomics study
Ravcheev, Dmitry UL; Rakhmaninova, A.B.; Mironov, A.A. et al

in Molecular Biology (2005), 39(5), 727-740

Nitrate and nitrite are the most preferable electron acceptors in the absence of molecular oxygen. In the γ-proteobacterium Escherichia coli, nitrate and nitrite respiration is regulated by two homologous ... [more ▼]

Nitrate and nitrite are the most preferable electron acceptors in the absence of molecular oxygen. In the γ-proteobacterium Escherichia coli, nitrate and nitrite respiration is regulated by two homologous tran- scription factors, NarL and NarP. Although this regulatory system was a subject of intensive research for more than 20 years, many key issues, including the structure of the NarL-binding site, are still unclear. Comparative genomics analysis showed that only NarP is responsible for regulation in most γ-proteobacteria. The NarP reg- ulon was studied in ten genomes. Although its structure considerably differs among some genomes, the mech- anism regulating the nitrate and nitrite reduction genes is highly conserved. A correlation was observed between the evolutionary changes in the nitrate and nitrite respiration system and the relevant regulatory system. Poten- tial NarP-binding sites were found upstream of the gene for the global regulator FNR and the sydAB, mdh, and sucAB aerobic metabolism genes. It was assumed on the basis of this evidence that the role of NarP in regulat- ing respiration changed during evolution. In total, 35 new operons were assigned to the generalized NarP reg- ulon. Autoregulation of the narQP operon was suggested for bacteria of the family Vibrionaceae. [less ▲]

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See detailHyperideal circle patterns
Schlenker, Jean-Marc UL

in Mathematical Research Letters (2005), 12(1), 85--102

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See detailElectrolyte effects on the nematic-isotropic phase transition in lyotropic liquid crystals
Mukherjee, Prabir K.; Lagerwall, Jan UL; Giesselmann, Frank

in Liquid Crystals (2005), 32(10), 1301-1306

A phenomenological approach to the description of the electrolyte effect on the nematic– isotropic phase transition in lyotropic liquid crystals is proposed. The influence of the electrolyte is discussed ... [more ▼]

A phenomenological approach to the description of the electrolyte effect on the nematic– isotropic phase transition in lyotropic liquid crystals is proposed. The influence of the electrolyte is discussed by varying the coupling between the concentration variables and the orientational order parameter. The analysis shows that the discontinuity in the first order nematic–isotropic phase transition as measured by TNI{T0 increases as a function of the NI weight fraction of the electrolyte. Here TNI is the first order nematic–isotropic phase transition temperature and TN0I is the extrapolated supercooling limit. The electrolyte dependence of the Cotton–Mouton coefficient and the non-linear dielectric effect in the isotropic phase above the nematic–isotropic phase transition are calculated. The theoretical predictions are found to be in good agreement with experimental results. [less ▲]

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See detailA rigidity criterion for non-convex polyhedra
Schlenker, Jean-Marc UL

in Discrete and Computational Geometry (2005), 33(2), 207--221

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See detailSens dessus dessous : lecture sémiolinguistique de l’espace dans l’œuvre d’Edgar P. Jacobs
Freyermuth, Sylvie UL

in Belphégor, Revue électronique de littérature populaire et de culture médiatique (2005), 5(1),

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See detailIn Celluloidgewittern : Die mediale Konstruktion von Wissenschaft und Technik als Paradigma des Ersten Weltkrieges
Fengler, Silke; Krebs, Stefan UL

in Technikgeschichte (2005), 72(3), 227-241

Der Beitrag setzt sich kritisch mit der Inszenierung (und Bewertung der Rolle?) von Wissenschaft und Technik im Ersten Weltkrieg in populärwissenschaftlichen deutschen TV-Dokumentationen auseinander. Er ... [more ▼]

Der Beitrag setzt sich kritisch mit der Inszenierung (und Bewertung der Rolle?) von Wissenschaft und Technik im Ersten Weltkrieg in populärwissenschaftlichen deutschen TV-Dokumentationen auseinander. Er leistet einen Beitrag zur Diskussion um den Umgang mit Bildern in der Geschichtswissenschaft und ihrer Verwendung zur medialen Konstruktion von Vergangenheit. Die problematische Kernaussage der TV-Dokumentatoren – natur- und ingenieurwissenschaftliche Forschung und Entwicklung neuer Waffensysteme sowie die industrielle Massenfertigung von Rüstungsgütern und ihr ungehemmter Einsatz hätten der Kriegsführung eine völlig neue, moderne Dimension, wird im ersten Teil anhand aktueller Forschungsergebnisse zum Ersten Weltkrieg kritisch beleuchtet. Dabei zeigt sich, dass Wissenschaft und Technik tatsächlich nur einen Teilaspekt des vielschichtigen, normativ aufgeladenen Phänomens der Moderne darstellen, die Filmemacher also mit einem verengten Modernitätsbegriff arbeiten. (Das eigentliche Wesen des Ersten Weltkriegs – die Gleichzeitigkeit moderner und rückständiger Elemente – gerät in den Dokumentationen aus dem Blick?) Der zweite Teil des Beitrags beschäftigt sich mit der Inszenierungsform (mit den Modalitäten der Inszenierung? mit der Art und Weise der Inszenierung?) zeitgenössischen Bildmaterials und fragt nach möglichen Ursachen für die von den TV-Autoren gewählte Darstellungs- und Erzählform. Die Entscheidung der Filmemacher, ihre Erzählung anhand einer durchgehenden Illustrierung mit zeitgenössischem Bildmaterial zu entwickeln, hat gravierende Folgen für die Erzählinhalte: eine ausführliche Bildanalyse zeigt, dass die Autoren der inneren Logik zeitgenössischer Filmaufnahmen und den darin eingravierten Diskursen in weiten Teilen folgen. Die Bildauswahl und –kommentierung verzichtet auf eine quellenkritische Analyse, was die oben erwähnte verkürzte (verzerrte?) Darstellung des Ersten Weltkrieges zur Folge hat. Rekombinationen zeitgenössischer Aufnahmen tragen auch dazu bei, eine – von heutigen ästhetischen Konzepten geprägte – Idee des modernen Krieges zu perpetuieren. Und schließlich knüpft die spezifische Darstellungs- und Erzählform über den Ersten Weltkrieg an aktuelle Strömungen der bundesdeutschen Erinnerungskultur an. [less ▲]

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See detailExclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader–Willi syndrome
Runte, Maren UL; Varon, R; Horn, D et al

in Human Genetics (2005), 116(3), 228-230

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See detailMapping of Microwave-Induced Phonons by µ-Brillouin Spectroscopy: Hypersons in ZnO on Silicon
Krüger, Jan-Kristian UL; Mainka, J.; Alnot, Patrick et al

in Journal de Physique IV (2005), 129

From the structural point of view a simple Cauchy relation is not expected to hold for isotropic materials. Such a Cauchy relation would imply the reduction of independent elastic stiffness constants for ... [more ▼]

From the structural point of view a simple Cauchy relation is not expected to hold for isotropic materials. Such a Cauchy relation would imply the reduction of independent elastic stiffness constants for the isotropic state from two to one. However, high frequency elastic data of glasses and viscous liquids show a linear transformation between the shear and the longitudinal elastic stiffness which is called a generalized Cauchy relation. It seems, that the parameters of the linear transformation are related to the global and local symmetry and/or order. Brillouin investigations on the elastic stiffness coefficients of a consolidated nano-crystalline material (CeO2) and of DGEBA/SiO2 nano-composites are used in order to elucidated the role of the discrepancy between local and global symmetry and/or order. [less ▲]

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See detailMathis Leibetseder: Die Kavalierstour. Adelige Erziehungsreisen im 17. und 18. Jahrhundert
Tröhler, Daniel UL

in Zeitschrift für Pädagogik (2005), 51

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See detailUncertainty of absolute gravity measurements
Van Camp, Michel; Williams, Simon D. P.; Francis, Olivier UL

in Journal of Geophysical Research (2005), 110(B05406), 1-9

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See detailQuelle Europe est née au Moyen Age?
Pauly, Michel UL

in Francia (2005), 32(1), 157-165

Compte rendu critique du livre de Jacques Le Goff, L'Europe est-elle née au Moyen Age?

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See detailGeographical agglomeration: the Case of Belgian manufacturing industry
Bertinelli, Luisito UL; Decrop, Jehan

in Regional Studies (2005), 39 (5)

The aim of this study is to provide a comprehensive discussion of the use of the Ellison and Glaeser index and subsequently to carry out a descriptive analysis of the geographical concentration of the ... [more ▼]

The aim of this study is to provide a comprehensive discussion of the use of the Ellison and Glaeser index and subsequently to carry out a descriptive analysis of the geographical concentration of the manufacturing sector in Belgium. To assess the degree of concentration, individual plant data on wage and salary earners are used, with a relatively fine geographical breakdown (districts and townships). It is shown that more than 30% of the industries are excessively agglomerated. [less ▲]

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See detail(Neue) Unübersichtlichkeit im Großherzogtum
Wille, Christian UL

in Forum für Politik, Gesellschaft und Kultur in Luxemburg (2005), (251), 15-19

2006 ist das Europäische Jahr der Arbeitskräftemobilität. Mobile Arbeitnehmer gewinnen also nicht nur in der Großregion an Bedeutung, auch auf Europäischer Ebene nimmt man sich verstärkt dieses Themas an ... [more ▼]

2006 ist das Europäische Jahr der Arbeitskräftemobilität. Mobile Arbeitnehmer gewinnen also nicht nur in der Großregion an Bedeutung, auch auf Europäischer Ebene nimmt man sich verstärkt dieses Themas an. Entscheidungsträger aus Politik, Wirtschaft und Beschäftigung befassen sich im SaarLorLux-Raum bereits seit Jahrzehnten intensiv mit Arbeitskräftemobilität. Dabei stehen das Grenzgängerwesen und überwiegend Arbeitsmarktfragen sowie Mobilitätshemmnisse im Zentrum. Die Diskussionen weiten sich aber auch auf benachbarte Themengebiete aus und Grenzgänger befinden sich zunehmend im Fokus der Raum- und Verkehrsplanung, der Immobilienmärkte, des Einzelhandels oder des nicht unumstrittenen Diskurses einer Europäischen Modellregion SaarLorLux... [less ▲]

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See detailTargeted proteolysis sustains calcineurin activation.
Burkard, Natalie; Becher, Jan; Heindl, Cornelia et al

in Circulation (2005), 111(8), 1045-53

BACKGROUND: Calcineurin (CnA) is important in the regulation of myocardial hypertrophy. We demonstrated that targeted proteolysis of the CnA autoinhibitory domain under pathological myocardial workload ... [more ▼]

BACKGROUND: Calcineurin (CnA) is important in the regulation of myocardial hypertrophy. We demonstrated that targeted proteolysis of the CnA autoinhibitory domain under pathological myocardial workload leads to increased CnA activity in human myocardium. Here, we investigated the proteolytic mechanism leading to activation of CnA. METHODS AND RESULTS: In patients with diseased myocardium, we found strong nuclear translocation of CnA. In contrast, in normal human myocardium, there was a cytosolic distribution of CnA. Stimulation of rat cardiomyocytes with angiotensin (Ang) II increased calpain activity significantly (433+/-11%; P<0.01; n=6) and caused proteolysis of the autoinhibitory domain of CnA. Inhibition of calpain by a membrane-permeable calpain inhibitor prevented proteolysis. We identified the cleavage site of calpain in the human CnA sequence at amino acid 424. CnA activity was increased after Ang II stimulation (310+/-29%; P<0.01; n=6) and remained high after removal of Ang II (214+/-17%; P<0.01; n=6). Addition of a calpain inhibitor to the medium decreased CnA activity (110+/-19%; P=NS; n=6) after removal of Ang II. Ang II stimulation of cardiomyocytes also translocated CnA into the nucleus as demonstrated by immunohistochemical staining and transfection assays with GFP-tagged CnA. Calpain inhibition and therefore suppression of calpain-mediated proteolysis of CnA enabled CnA exit from the nucleus. CONCLUSIONS: Ang II stimulation of cardiomyocytes increased calpain activity, leading to proteolysis of the autoinhibitory domain of CnA. This causes an increase in CnA activity and results in nuclear translocation of CnA. Loss of the autoinhibitory domain renders CnA constitutively nuclear and active, even after removal of the hypertrophic stimulus. [less ▲]

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See detailPolen in Wit-Rusland: Een boksmatch met internationaal karakter
Venken, Machteld UL

in Oost-Europa Tijdingen (2005)

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See detailWedge-shaped layers from porous silicon: the basics of laterally graded interference filters
Bohn, H. G.; Marso, Michel UL

in Physica Status Solidi A. Applied Research (2005), 202(8), 1437-1442

The process of making laterally graded interference filters has been reanalyzed. A simple and consistent picture arises if one applies a constant electric field perpendicular to the etch current instead ... [more ▼]

The process of making laterally graded interference filters has been reanalyzed. A simple and consistent picture arises if one applies a constant electric field perpendicular to the etch current instead of a constant current. The system is quantitatively modeled by means of a pure ohmic equivalent circuit model. [less ▲]

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See detailForeign Environments: The Internationalisation of Environmental Producer Services.
Schulz, Christian UL

in Service Industries Journal (2005), 25(3), 337-354

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See detailExtensive and intensive growth in a neoclassical framework
Irmen, Andreas UL

in Journal of Economic Dynamics and Control (2005), 29(8), 1427-1448

Extensive growth based on the expansion of inputs is likely to be subject to diminishing returns. Therefore it is often viewed as having no effect on per capita magnitudes in the long run. This Paper ... [more ▼]

Extensive growth based on the expansion of inputs is likely to be subject to diminishing returns. Therefore it is often viewed as having no effect on per capita magnitudes in the long run. This Paper argues that periods of extensive growth through capital accumulation may be a precursor to periods of intensive growth during which output per unit of input grows through endogenous technical change. Such a sequence of stages of development occurs as capital accumulation affects the incentives to engage in labour-saving technical change. A steady rise in the capital-labour ratio affects the relative scarcity of factors of production, their (expected) relative price, and induces innovation investments.<P>(This abstract was borrowed from another version of this item.) [less ▲]

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See detailRaman spectra of BN nanotubes: Ab initio and bond-polarizability model calculations
Wirtz, Ludger UL; Lazzeri, M.; Mauri, F. et al

in Physical Review. B, Condensed Matter and Materials Physics (2005), 71(24),

We present ab initio calculations of the nonresonant Raman spectra of zigzag and armchair BN nanotubes. In comparison, we implement a generalized bond-polarizability model where the parameters are ... [more ▼]

We present ab initio calculations of the nonresonant Raman spectra of zigzag and armchair BN nanotubes. In comparison, we implement a generalized bond-polarizability model where the parameters are extracted from first-principles calculations of the polarizability tensor of a BN sheet. For light polarization along the tube axis, the agreement between model and ab initio spectra is almost perfect. For perpendicular polarization, depolarization effects have to be included in the model in order to reproduce the ab initio Raman intensities. [less ▲]

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See detailDiuretic usage in heart failure: a continuing conundrum in 2005.
Gupta, S.; Neyses, Ludwig UL

in European heart journal (2005), 26(7), 644-9

Several large well-designed clinical trials have shown that the use of diuretics is beneficial in patients with hypertension. However, similarly robust data regarding their role in chronic heart failure ... [more ▼]

Several large well-designed clinical trials have shown that the use of diuretics is beneficial in patients with hypertension. However, similarly robust data regarding their role in chronic heart failure are lacking. Historically, diuretics were developed for treatment of sodium and water retention in oedematous disorders and clinically, they remain the most potent drugs available to relieve symptoms and eliminate oedema in the congested patient with heart failure. In the non-congested patient, however, diuretics continue to be used on a purely clinical basis without sufficient characterization of benefits, adverse effects, and potential influence on mortality. There are also concerns that chronic diuretic usage can cause adverse vascular effects, unfavourable neuroendocrine activation, electrolyte imbalances, and life-threatening arrhythmias. In this article, we review the limited evidence available regarding the benefits and perils of using diuretics in heart failure. [less ▲]

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See detailWirtschaftsverkehr in Stadt und Umland - Ein neues Tätigkeitsfeld für "integrierte Planung"
Hesse, Markus UL

in Verkehrszeichen : für Mobilität und Umwelt (2005), (1), 12-16

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See detailDie Exklusion von Schüler/innen mit sonderpädagogischem Förderbedarf. Ein Beitrag zur Debatte um nationale Bildungsstandards und die Schule für alle
Pfahl, Lisa; Powell, Justin J W UL

in Gemeinsam Leben: Zeitschrift für Integrative Erziehung (2005), (10), 68-78

Aktuelle bildungspolitische Reformbemühungen zielen darauf, eine Erhöhung der schulischen Leistungen zu bewirken und messbare Kompetenzen weiter zu entwickeln. Dabei wird die Selektion von Schüler/innen ... [more ▼]

Aktuelle bildungspolitische Reformbemühungen zielen darauf, eine Erhöhung der schulischen Leistungen zu bewirken und messbare Kompetenzen weiter zu entwickeln. Dabei wird die Selektion von Schüler/innen mit sonderpädagogischem Förderbedarf durch die Institution Schule und die Frage nach der Chancengleichheit eines segregierenden Schulsystems eher selten thematisiert. Statt solcher "Strukturfragen" stehen die Forderungen nach nationalen Bildungsstandards, Ganztagsschulen und der Kultushoheit der Bundesländer im Mittelpunkt der Diskussion. Die Idee einer individuellen Förderung von Schüler/innen, evtl. sogar in einer Schule für alle, wird seit PISA 2003 zunehmend Gegenstand der gesellschaftlichen Diskussion. Jedoch bleiben sonderpädagogische Förderprogramme trotz deren Spezialisierung auf solche individualisierte Unterrichtsformen, unberücksichtigt. Anhand zweier unterschiedlicher Ansätze in der Bildungsforschung - biographische Analysen und gesellschaftshistorische Vergleiche - werden die Autoren aufzeigen, dass die weitgehende Nicht-Berücksichtigung des sonderpädagogischen Bereichs in der allgemeinen Bildungsforschung die Scheiternserfahrungen von Kindern und Jugendlichen mit sonderpädagogischem Förderungsbedarf ausblendet, und die (inter)nationalen Ergebnisse von PISA, sowie die ermittelten - oder zu ermittelnden - "nationalen Bildungsstandards" verzerrt. Gerade die Situation von Kindern und Jugendlichen mit sonderpädagogischem Förderbedarf an Sonderschulen unterstreicht die Wichtigkeit der aktuellen Diskussion um eine Schule für alle. Eine solche Schulform wäre ohne diese Schüler/innen lediglich eine weitere exkludierende Schulform, denn Schulen ohne behinderte Kinder ist keine normalen Schulen. [less ▲]

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See detailTopology of small-world networks of protein-protein complex structures.
del Sol Mesa, Antonio UL; Fujihashi, Hirotomo; O'Meara, Paul

in Bioinformatics (2005), 21(8), 1311-5

The majority of real examples of small-world networks exhibit a power law distribution of edges among the nodes, therefore not fitting into the wiring model proposed by Watts and Strogatz. However ... [more ▼]

The majority of real examples of small-world networks exhibit a power law distribution of edges among the nodes, therefore not fitting into the wiring model proposed by Watts and Strogatz. However, protein structures can be modeled as small-world networks, with a distribution of the number of links decaying exponentially as in the case of this wiring model. We approach the protein-protein interaction mechanism by viewing it as a particular rewiring occurring in the system of two small-world networks represented by the monomers, where a re-arrangement of links takes place upon dimerization leaving the small-world character in the dimer network. Due to this rewiring, the most central residues at the complex interfaces tend to form clusters, which are not homogenously distributed. We show that these highly central residues are strongly correlated with the presence of hot spots of binding free energy. CONTACT: ao-mesa@fujirebio.co.jp SUPPLEMENTARY INFORMATION: http://www.fujirebio.co.jp/support/index.php (under construction). [less ▲]

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See detailCyclophilin a binds to linear peptide motifs containing a consensus that is present in many human proteins
Piotukh, K.; Gu, Wei UL; Kofler, M. et al

in Journal of Biological Chemistry (2005), 280(25), 23668-23674

Cyclophilin A ( CypA) is a peptidyl-prolyl cis/trans-isomerase that is involved in multiple signaling events of eukaryotic cells. It might either act as a catalyst for prolyl bond isomerization, or it can ... [more ▼]

Cyclophilin A ( CypA) is a peptidyl-prolyl cis/trans-isomerase that is involved in multiple signaling events of eukaryotic cells. It might either act as a catalyst for prolyl bond isomerization, or it can form stoichiometric complexes with target proteins. We have investigated the linear sequence recognition code for CypA by phage display and found the consensus motif FGPXLp to be selected after five rounds of panning. The peptide FGP-DLPAGD showed inhibition of the isomerase reaction and NMR chemical shift mapping experiments highlight the CypA interaction epitope. Ligand docking suggests that the peptide was able to bind to CypA in the cis- and trans-conformation. Protein Data Bank searches reveal that many human proteins contain the consensus motif, and several of these protein motifs are shown to interact with CypA in vitro. These sequences represent putative target sites for binding of CypA to intracellular proteins. [less ▲]

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See detailDifferences between smectic homo- and copolysiloxanes as a consequence of microphase separation
Rössle, Martin; Braun, L.; Schollmeyer, D. et al

in Liquid Crystals (2005), 32(5), 533-538

This paper compares smectic phases formed from LC-homo- and LC-co-polysiloxanes. In the homopolysiloxane, each repeating unit of the polymer chain is substituted with a mesogen, whereas in the ... [more ▼]

This paper compares smectic phases formed from LC-homo- and LC-co-polysiloxanes. In the homopolysiloxane, each repeating unit of the polymer chain is substituted with a mesogen, whereas in the copolysiloxanes mesogenic repeating units are separated by dimethylsiloxane units. Despite a rather similiar phase sequence of the homo- and co-polysiloxanes—higher ordered smectic, smectic C* (SmC*), smectic A (SmA) and isotropic—the nature of their phases differs strongly. For the copolymers the phase transition SmC* to SmA is second order and of the ‘de Vries’ type with a very small thickness change of the smectic layers. Inside the SmA phase, however, the smectic thickness decreases strongly on approaching the isotropic phase. For the homopolymer the phase transition SmC* to SmA is first order with a significant thickness change, indicating that this phase is not of the ‘de Vries’ type. This difference in the nature of the smectic phases is probably a consequence of microphase separation in the copolymer, which facilitates a loss of the tilt angle correlation between different smectic layers. This has consequences for the mechanical properties of LC- elastomers formed from homo- and co-polymers. For the elastomers from homopolymers the smectic layer compression seems to be rather high, while it seems to be rather small for the copolymers. [less ▲]

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See detailAn approach to qualify the intensity of mixing on a forward acting grate.
Peters, Bernhard UL; Dziugys, Algis; Hunsinger, H. et al

in Chemical Engineering Science (2005), (60/6), 1649-1659

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See detailOxidative stress activates MMP-2 in cultured human coronary smooth muscle cells
Valentin, F.; Bueb, Jean-Luc UL; Kieffer, P. et al

in Fundamental and Clinical Pharmacology (2005), 19(6), 661-7

Oxidative stress is a cardinal feature of the inflammatory process and is involved in various pathologies including atherosclerosis. One of the important mechanisms in which oxidative stress may play a ... [more ▼]

Oxidative stress is a cardinal feature of the inflammatory process and is involved in various pathologies including atherosclerosis. One of the important mechanisms in which oxidative stress may play a role is activation of matrix metalloproteinases such as MMP-2, which are involved in plaque destabilization. We investigated the mechanisms by which oxidative stress induces MMP-2 activation in cultured human coronary artery smooth muscle cells. Using zymography and Western blot analysis, we showed that oxidized low-density lipoproteins activate MMP-2 through up-regulation of the expression and activation of a membrane-type 1 matrix metalloproteinase (MT1-MMP). A second mechanism of MMP-2 activation involves oxidative radicals generated by the xanthine/xanthine oxidase complex (X/Xo). Research on these two mechanisms of MMP activation could lead to the elaboration of new vascular therapies for the treatment of atheroma based on interruption of a specific oxidative stress pathway. [less ▲]

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See detailItô's and Tanaka's type formulae for the stochastic heat equation: the linear case
Gradinaru, Mihai; Nourdin, Ivan UL; Tindel, Samy

in Journal of Functional Analysis (2005), 228(1), 114-143

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See detailNon-communicative multi-robot coordination in dynamic environments
Kok, J. R.; Spaan, M. T. J.; Vlassis, Nikos UL

in Robotics & Autonomous Systems (2005), 50(2-3), 99-114

Within a group of cooperating agents the decision making of an individual agent depends on the actions of the other agents. In dynamic environments, these dependencies will change rapidly as a result of ... [more ▼]

Within a group of cooperating agents the decision making of an individual agent depends on the actions of the other agents. In dynamic environments, these dependencies will change rapidly as a result of the continuously changing state. Via a context-specific decomposition of the problem into smaller subproblems, coordination graphs offer scalable solutions to the problem of multiagent decision making. In this work, we apply coordination graphs to a continuous (robotic) domain by assigning roles to the agents and then coordinating the different roles. Moreover, we demonstrate that, with some additional assumptions, an agent can predict the actions of the other agents, rendering communication superfluous. We have successfully implemented the proposed method into our UvA Trilearn simulated robot soccer team which won the RoboCup-2003 World Championship in Padova, Italy. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailSubversionen der Erinnerung im postdramatischen Theater. Heiner Müller - Elfriede Jelinek - Rainald Goetz
Heimböckel, Dieter UL

in Der Deutschunterricht: Beiträge zu seiner Praxis und wissenschaftlichen Grundlegung (2005), 57(6), 46-53

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See detailCalcium transport in cardiovascular health and disease--the sarcolemmal calcium pump enters the stage.
Cartwright, Elizabeth J.; Schuh, Kai; Neyses, Ludwig UL

in Journal of Molecular and Cellular Cardiology (2005), 39(3), 403-6

Calcium is known to be one of the most important ionic regulators of the heart, where it has a crucial role in contraction-relaxation. Within a single beat of the cardiomyocyte there is a 100-fold ... [more ▼]

Calcium is known to be one of the most important ionic regulators of the heart, where it has a crucial role in contraction-relaxation. Within a single beat of the cardiomyocyte there is a 100-fold increase in the cytosolic free Ca(2+) level, this must be returned to its original concentration in order to maintain the normal physiological function of the cell. Two of the mechanisms involved in returning the Ca(2+) concentration back to resting levels are located at the sarcolemma; the sodium/calcium exchanger (NCX) and the sarcolemmal calcium pump. Compared to the NCX the sarcolemmal calcium pump extrudes significantly less calcium from the cardiomyocyte and has long been thought to be involved in the maintenance of low diastolic calcium levels. This review will outline recent evidence suggesting that the sarcolemmal calcium pump may in fact play a key role in signal transduction in the cardiovascular system. [less ▲]

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See detailUmberto Eco: Die geheimnisvolle Flamme der Königin Loana. Ein Buchtipp.
Küpper, Achim UL

in http ://www.arte-tv.com (2005)

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See detailOAKHQOL: a new instrument to measure quality of live in knee and hip Osteoarthritis
Rat, AC.; Coste, J.; Pouchot, J. et al

in Journal of Clinical Epidemiology (2005), 58

To develop a questionnaire with which to measure quality of life (QoL) in patients with knee and hip osteoarthritis (OA). Study Design and Setting: Thirty-two caregivers and 96 OA patients were ... [more ▼]

To develop a questionnaire with which to measure quality of life (QoL) in patients with knee and hip osteoarthritis (OA). Study Design and Setting: Thirty-two caregivers and 96 OA patients were interviewed individually (using cognitive and face-to-face techniques) and in focus groups. A group of experts working independently at first and then consensually used the interview transcripts to generate a 46-item questionnaire. Results: Analysis of questionnaires completed by 263 patients with hip or knee OA resulted in the exclusion of three items (two because of low reliability and one because of a low response rate). Principal component analysis revealed four factors: physical activity, mental health, social functioning, and social support. A pain dimension was individualized. Preliminary testing showed the reliability of the five dimensions to be satisfactory (intraclass correlation coefficients: 0.70–0.85), construct validity was adequate when correlated with the SF36 (Spearman correlation coefficients: 0.43–0.75), and discrimination was satisfactory. The osteoarthritis knee and hip quality of life questionnaire (OAKHQOL) consists of 43 items in five dimensions and three independent items. Conclusion: TheOAKHQOLis the first specific knee and hipOAquality of life instrument. Its development followed an a priori structured strategy to ensure content validity. It meets psychometric requirements for validity and reliability. [less ▲]

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See detailPhotomixers fabricated on nitrogen-ion-implanted GaAs
Mikulics, M.; Marso, Michel UL; Cámara Mayorga, I. et al

in Applied Physics Letters (2005), 87(4), 41106-1-3

We report on fabrication and measurement of photomixers based on nitrogen-ion-implanted GaAs. We used energies of 500 keV, 700 keV, and 880 keV to implant N+ ions into GaAs substrates with an ion ... [more ▼]

We report on fabrication and measurement of photomixers based on nitrogen-ion-implanted GaAs. We used energies of 500 keV, 700 keV, and 880 keV to implant N+ ions into GaAs substrates with an ion concentration of 3 1012 cm−2. The resulting material exhibited 110 fs carrier lifetime due to implantation-induced defects. Our photomixers were fabricated as metal-semiconductor-metal devices, placed at the feed point of a broadband antenna. Optoelectronic measurements were performed in the wavelength range between 350 nm and 950 nm. In comparison to their counterparts photomixers fabricated on low-temperature-grown GaAs the N+-implanted GaAs photomixers exhibit improvements on both the output power and responsivity. A maximal responsivity of above 100 mA/W was achieved and we did not observe any dependence of the mixer cut-off frequency on the bias voltage. These characteristics make N+-implanted GaAs the material of choice for efficient optoelectronic photomixers. [less ▲]

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See detailA new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading
Salsmann, Alexandre UL; Schaffner-Reckinger, Elisabeth UL; Kabile, Fabrice UL et al

in Journal of Biological Chemistry (2005), 280(39), 33610-33619

A number of RGD-type integrins rely on a synergistic site in addition to the canonical RGD site for ligand binding and signaling, although it is still unclear whether these two recognition sites function ... [more ▼]

A number of RGD-type integrins rely on a synergistic site in addition to the canonical RGD site for ligand binding and signaling, although it is still unclear whether these two recognition sites function independently, synergistically, or competitively. Experimental evidence has suggested that fibrinogen binding to the RGD-type integrin alphaIIbbeta3 occurs exclusively through the synergistic gamma(400-411) sequence, thus questioning the functional role of the RGD recognition site. Here we have investigated the respective role of the fibrinogen gamma(400-411) sequence and the RGD motif in the molecular events leading to ligand-induced alphaIIbbeta3-dependent Chinese hamster ovary (CHO) cell or platelet spreading, by using intact fibrinogen and well characterized plasmin-generated fibrinogen fragments containing either the RGD motif (fragment C) or the gamma(400-411) sequence (fragment D), and CHO cells expressing resting wild type (alphaIIbbeta3wt), constitutively active (alphaIIbbeta3T562N), or non-functional (alphaIIbbeta3D119Y) receptors. Our data provide evidence that the gamma(400-411) site by itself is able to initiate alphaIIbbeta3 clustering and recruitment of intracellular proteins to early focal complexes, mediating cell attachment, FAK phosphorylation, and Rac1 activation, while the RGD motif subsequently acts as a molecular switch on the beta3 subunit to trigger cell spreading. More importantly, we show that the premier functional role of the RGD site is not to reinforce cell attachment but, rather, to imprint a conformational change on the beta3 subunit leading to maximal RhoA activation and actin cytoskeleton organization in CHO cells as well as in platelets. Finally, alphaIIbbeta3-dependent RhoA stimulation and cell spreading, but not cell attachment, are Src-dependent and phosphoinositide 3-kinase-independent and are inhibited by the Src antagonist PP2. [less ▲]

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See detailFine Disintegration of the Left Regular Representation
Ludwig, Jean; Molitor-Braun, Carine UL

in Journal of Algebra and Its Applications (2005), 4(6), 683-706

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See detailWhen will smart antennas be ready for the market? Part I
Kaiser, T.; Bourdoux, A.; Choi, S. et al

in EURASIP Journal on Wireless Communications and Networking (2005), 22(2), 87-92

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See detailAufgeklärte Pädagogen. Die Erziehungswissenschaft und das geistige Erbe Pierre Bourdieus
Neumann, Sascha UL

in Vierteljahresschrift für wissenschaftliche Pädagogik (2005), 81(3), 345-351

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See detailNucleation in suspensions of anisotropic colloids
Schilling, Tanja UL; Frenkel, Daan

in Computer Physics Communications (2005), 169(1-3), 117-121

We report Monte Carlo studies of liquid crystal nucleation in two types of anisotropic colloidal systems: hard rods and hard ellipsoids. In both cases we find that nucleation pathways differ strongly from ... [more ▼]

We report Monte Carlo studies of liquid crystal nucleation in two types of anisotropic colloidal systems: hard rods and hard ellipsoids. In both cases we find that nucleation pathways differ strongly from the pathways in systems of spherical particles. Short hard rods show an effect of self-poisoning. This part of the article is based on a previous publication [T. Schilling, D. Frenkel, Self-poisoning of crystal nuclei in hard-rod liquids, Phys. Rev. Lett. 92 (2004) 085505]. When a crystallite forms, its surfaces are covered preferentially by rods which align perpendicular to the surface. Therefore subsequent growth is stunted. Hard, almost spherical ellipsoids can be compressed to very high densities without crystallization—in contrast to hard spheres, which crystallize easily. When forced to crystallize, ellipsoids form very loosely aggregated nuclei. In both cases nucleation pathways are complex and it is therefore difficult to define an appropriate reaction coordinate. The common strategies of investigation of nucleation problems (i.e. definition of a coordinate and then sampling barrier crossing with well-known techniques) fail in these systems. [less ▲]

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See detailSynthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
Freundlich, Joel S.; Anderson, John W.; Sarantakis, Dimitri et al

in Bioorganic & Medicinal Chemistry Letters (2005), 15(23), 5247-52

A structure-based approach has been taken to develop 4'-substituted analogs of triclosan that target the key malarial enzyme Plasmodium falciparum enoyl acyl carrier protein reductase (PfENR). Many of ... [more ▼]

A structure-based approach has been taken to develop 4'-substituted analogs of triclosan that target the key malarial enzyme Plasmodium falciparum enoyl acyl carrier protein reductase (PfENR). Many of these compounds exhibit nanomolar potency against purified PfENR enzyme and modest (2-10microM) potency against in vitro cultures of drug-resistant and drug-sensitive strains of the P. falciparum parasite. X-ray crystal structures of nitro 29, aniline 30, methylamide 37, and urea 46 demonstrate the presence of hydrogen-bonding interactions with residues in the active site and point to future rounds of optimization to improve compound potency against purified enzyme and intracellular parasites. [less ▲]

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See detail'Dozivotno ucenje' kao conditio humana: Pledoaje za jedan revidirani pojam ucenja
Tröhler, Daniel UL

in Andragoške Studije (2005), 11

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See detailLa CJCE admet l'irresponsabilité des autorités de contrôle des banques vis-à-vis des déposants
Prüm, André UL

in Revue de Droit Bancaire et Financier (2005), (1),

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See detailGenerating anomalous elliptic curves
Leprévost, Franck UL; Monnerat, Jean; Varrette, Sébastien UL et al

in Information Processing Letters (2005), 93

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See detailProgressive sleep 'destructuring' in Parkinson's disease. A polysomnographic study in 46 patients.
Diederich, Nico UL; Vaillant, Michel; Mancuso, Giovanna UL et al

in Sleep medicine (2005), 6(4), 313-8

BACKGROUND: Sleep abnormalities in Parkinson's disease (PD) are frequent, but it is unknown whether or not there is progressive loss of physiological sleep architecture or what the causes could be ... [more ▼]

BACKGROUND: Sleep abnormalities in Parkinson's disease (PD) are frequent, but it is unknown whether or not there is progressive loss of physiological sleep architecture or what the causes could be. METHODS: Retrospective review of medical records and polysomnographic data from 46 non-demented PD patients. RESULTS: Sleep latency was correlated with disease duration (F1,44=4.87, P=0.03). Total sleep time (F1,44=8.54, P=0.005), deep sleep time (F1,44=4.06, P=0.05), REM sleep time (F1,44=9.15, P=0.004) and sleep efficiency (SE) (F1,44=10.20, P=0.003) were inversely correlated with disease duration. The same sleep parameters were independent from the degree of motor impairment, dosage of the dopaminergic medications, and age. Subjective sleep complaints could only partially predict abnormalities in polysomnographic (PSG) studies. CONCLUSION: In PD nocturnal sleep 'destructuring' is linked to disease duration and evolves independently from other major disease parameters. [less ▲]

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See detailChronique de droit bancaire - Mars à septembre 2005 : des solutions réalistes et une personnalisation de la relation bancaire
Prüm, André UL; Mattout, Jean-Pierre

in Droit & Patrimoine (2005), (143), 96

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See detailExploring a spatio-dynamic neighbourhood-based model of residential behaviour in the Brussels periurban area
Caruso, Geoffrey UL; Rounsevell, Mark; Cojocaru, George

in International Journal of Geographical Information Science (2005), 19(2), 103-123

This article proposes a methodology for the construction and the calibration of a micro-economic urban land-use model within an extended Cellular Automata (CA) framework. The methodology is applied to ... [more ▼]

This article proposes a methodology for the construction and the calibration of a micro-economic urban land-use model within an extended Cellular Automata (CA) framework. The methodology is applied to processes of residential spread in a part of the commuting periphery of Brussels. The model hypothesizes that households effect on urban development, through their valuation of neighbourhood externalities. A coarse sensitivity analysis is undertaken in order to explore the relationship between household neighbourhood preferences and emerging spatial morphologies. These macro-structures are measured with different indices in order to parameterize the model. [less ▲]

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See detailInfluence of passivation-induced stress on the performance of AlGaN/GaN HEMTs
Gregusova, Dagmar; Bernát, J.; Drzik, M. et al

in Physica Status Solidi C. Current Topics in Solid State Physics (2005), 2(7), 2619-2622

This paper reports on properties of intentionally undoped AlGaN/GaN/sapphire-based high electron mobility transistors (HEMTs) before and after passivation with SiO2 and Si3N4. Our results indicate that ... [more ▼]

This paper reports on properties of intentionally undoped AlGaN/GaN/sapphire-based high electron mobility transistors (HEMTs) before and after passivation with SiO2 and Si3N4. Our results indicate that the DC performance of the AlGaN/GaN HEMTs improved significantly as the stress in the passivation layer increased from compressive to tensile. It corresponded to changes in the sheet carrier concentration. Unlike the DC properties, RF properties of the HEMTs were less sensitive to the stress. [less ▲]

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See detailPerseus: Randomized point-based value iteration for POMDPs
Spaan, M. T. J.; Vlassis, Nikos UL

in Journal of Artificial Intelligence Research (2005), 24

Partially observable Markov decision processes (POMDPs) form an attractive and principled framework for agent planning under uncertainty. Point-based approximate techniques for POMDPs compute a policy ... [more ▼]

Partially observable Markov decision processes (POMDPs) form an attractive and principled framework for agent planning under uncertainty. Point-based approximate techniques for POMDPs compute a policy based on a finite set of points collected in advance from the agent's belief space. We present a randomized point-based value iteration algorithm called Perseus. The algorithm performs approximate value backup stages, ensuring that in each backup stage the value of each point in the belief set is improved; the key observation is that a single backup may improve the value of many belief points. Contrary to other point-based methods, Perseus backs up only a (randomly selected) subset of points in the belief set, sufficient for improving the value of each belief point in the set. We show how the same idea can be extended to dealing with continuous action spaces. Experimental results show the potential of Perseus in large scale POMDP problems. [less ▲]

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See detailProduction of ultracold neutrons from a cold neutron beam on a 2H2 target
Atchison, F.; van den Brandt, B.; Brys, T. et al

in Physical Review. C, Nuclear Physics (2005), 71

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See detailSigismund von Luxemburg, König von Ungarn und Kaiser, 1387-1437, 08.06.2005 – 10.06.2005 Luxemburg
Uhrmacher, Martin UL

in H-Soz-Kult: Kommunikation und Fachinformation für die Geschichtswissenschaften (2005)

Vom 8. bis 10. Juni fand in Luxemburg eine internationale Tagung statt zum Thema Sigismund von Luxemburg, König von Ungarn und Kaiser, 1387-1437. Der Kongress stand im Vorfeld der von Ungarn und Luxemburg ... [more ▼]

Vom 8. bis 10. Juni fand in Luxemburg eine internationale Tagung statt zum Thema Sigismund von Luxemburg, König von Ungarn und Kaiser, 1387-1437. Der Kongress stand im Vorfeld der von Ungarn und Luxemburg gemeinsam organisierten Ausstellung SIGISMUNDUS REX ET IMPERATOR. 1387-1437, die im nächsten Jahr in Budapest eröffnet wird (15. März - 18. Juni 2006) und anschließend nach Luxemburg kommt (13. Juli - 15. Oktober 2006). Er diente somit der wissenschaftlichen Standortbestimmung und der Diskussion des aktuellen Forschungsstandes zur Herrschaft Sigismunds von Luxemburg, König von Ungarn (1387), König (1410/11) und Kaiser (1433) des Heiligen Römischen Reiches, die von bedeutenden historischen und intellektuellen Umwälzungen geprägt war. Im Zentrum des Interesses standen weniger bekannte Aspekte der Persönlichkeit und des Wirkens von Sigismund sowie des Kunstschaffens seiner Zeit Die Referate behandelten dabei den Raum über Sigismunds Herrschaftsbereiche und das Heilige Römische Reich hinaus, er reichte vom skandinavisch-baltischen Raum über England, Frankreich, Burgund, die Eidgenossenschaft, Italien, Polen und den Balkan bis zum aufstrebenden Osmanischen Reich. Dieser große Wirkungsbereich Sigismunds spiegelte sich auch in der Referentenliste, die neben Teilnehmern aus Deutschland und Ungarn auch Referenten aus Tschechien, der Slowakei, Slowenien, Kroatien, der Schweiz, Italien, Frankreich, Österreich und den USA umfasste. [less ▲]

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See detailForum non Conveniens and the Brussels Convention
Cuniberti, Gilles UL

in International Law and Comparative Law Quarterly (2005)

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See detailHierarchisches Selbstinteresse und Fremdenfeindlichkeit bei Jugendlichen. Gruppendynamik
Hadjar, Andreas UL

in Gruppendynamik (2005), 36(1), 103-126

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See detailSupply and Demand, Allocation and Wage Inequality: An International Comparison
Dupuy, Arnaud UL; Borghans, Lex

in Applied Economics (2005)

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See detailSiO2 /AlGaN/GaN MOSHFET with 0.7 µm gate-length and fmax / fT of 40/24 GHz
Bernát, J.; Gregusová, D.; Heidelberger, G. et al

in Electronics Letters (2005), 41(11), 667-668

The performance of SiO2/AlGaN/GaN MOSHFETs is described. The C–V measurements showed slight increase in sheet carrier density after applying 12 nm-thick PECVD SiO2. The devices exhibited gate leakage ... [more ▼]

The performance of SiO2/AlGaN/GaN MOSHFETs is described. The C–V measurements showed slight increase in sheet carrier density after applying 12 nm-thick PECVD SiO2. The devices exhibited gate leakage current of 5 .10 ^-10 A/mm. Small-signal RF characterisation of 0.7 mm gate length devices yielded an fT of 24 GHz and an fmax of 40 GHz, which are comparable to those typical for state-of-the-art AlGaN/GaN HFETs. [less ▲]

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See detailGrowth and properties of GaN and AlN layers on silver substrates
Mikulics, Martin; Kočan, Martin; Rizzi, Angela et al

in Applied Physics Letters (2005), 87

We report on the preparation and properties of GaN and AlN layers grown by molecular-beam epitaxy on silver metal substrates. X-ray diffraction rocking curves show polycrystalline character of GaN with ... [more ▼]

We report on the preparation and properties of GaN and AlN layers grown by molecular-beam epitaxy on silver metal substrates. X-ray diffraction rocking curves show polycrystalline character of GaN with high preferential GaN 11-22 orientation. An intermetallic phase of Ga3Ag is found at the GaN/Ag interface. On the other hand, AlN layers exhibit a monocrystalline structure with a growth direction of 0002 . Schottky diodes prepared on GaN layers show good rectifying behavior and relatively low leakage current 10−3 A/cm2 . These results indicate that the III-nitride growth on metallic substrates might be used for low-cost and large-area electronic and photonic devices. [less ▲]

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See detailInterleukin-8 primes oxidative burst in neutrophil-like HL-60 through changes in cytosolic calcium
Bréchard, Sabrina UL; Bueb, Jean-Luc UL; Tschirhart, Eric UL

in Cell Calcium (2005), 37(6), 531-40

In response to a variety of stimuli, neutrophils release large amount of reactive oxygen species (ROS) generated by NADPH oxidase. This process known as the respiratory burst is dependent on cytosolic ... [more ▼]

In response to a variety of stimuli, neutrophils release large amount of reactive oxygen species (ROS) generated by NADPH oxidase. This process known as the respiratory burst is dependent on cytosolic free calcium concentration ([Ca(2+)](i)). Proinflammatory cytokines such as interleukin-8 (IL-8) may modulate ROS generation through a priming phenomenon. The aim of this study was to determine the effect of human IL-8 on ROS production in neutrophil-like dimethylsulfoxide-differentiated HL-60 cells (not equalHL-60 cells) and further to examine the role of Ca(2+) mobilization during the priming. IL-8 at 10 nM induced no ROS production but a [Ca(2+)](i) rise (254 +/- 36 nM). IL-8 induced a strongly enhanced (2 fold) ROS release during stimulation with 1 microM of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLF). This potentiation of ROS production is dependent of extracellular Ca(2+) (17.0+/-4.5 arbitrary units (A.U.) in the absence of Ca(2+) versus 56.6 +/- 3.9 A.U. in the presence of 1.25 mM of Ca(2+)). Also, IL-8 enhanced fMLF-stimulated increase in [Ca(2+)](i) (375 +/- 35 versus 245 +/- 21 nM, 0.1 microM of fMLF). IL-8 had no effect on not equalHL-60 cells in response to 1 microM of thapsigargin (472 +/- 66 versus 470 +/- 60 nM). In conclusion, Ca(2+) influx is necessary for a full induction of neutrophil priming by IL-8. [less ▲]

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See detailLa vidéosurveillance dans la ville : panacée contre la violence et la criminalité ?
Oesch, Lucas UL

in Vues sur la Ville (2005), (12), 2

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See detailExperimenting for Sustainable Transport. The approach of Strategic Niche Management
Hesse, Markus UL

in Journal of Transport Geography (2005), 13(1), 101-105

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See detailA quantitative analysis of fish consumption and stroke risk.
Bouzan, C.; Cohen, J. T.; Connor, W. E. et al

in American Journal of Preventive Medicine (2005), 29(4), 347-352

Although a rich source of n-3 polyunsaturated fatty acids (PUFAs) that may confer multiple health benefits, some fish contain methyl mercury (MeHg), which may harm the developing fetus. U.S. government ... [more ▼]

Although a rich source of n-3 polyunsaturated fatty acids (PUFAs) that may confer multiple health benefits, some fish contain methyl mercury (MeHg), which may harm the developing fetus. U.S. government recommendations for women of childbearing age are to modify consumption of high-MeHg fish to reduce MeHg exposure, while recommendations encourage fish consumption among the general population because of the nutritional benefits. The Harvard Center for Risk Analysis convened an expert panel (see acknowledgements) to quantify the net impact of resulting hypothetical changes in fish consumption across the population. This paper estimates the impact of fish consumption on stroke risk. Other papers quantify coronary heart disease mortality risk and the impacts of both prenatal MeHg exposure and maternal intake of n-3 PUFAs on cognitive development. This analysis identified articles in a recent qualitative literature review that are appropriate for the development of a dose-response relationship between fish consumption and stroke risk. Studies had to satisfy quality criteria, quantify fish intake, and report the precision of the relative risk estimates. The analysis combined the relative risk results, weighting each proportionately to its precision. Six studies were identified as appropriate for inclusion in this analysis, including five prospective cohort studies and one case-control study (total of 24 exposure groups). Our analysis indicates that any fish consumption confers substantial relative risk reduction compared to no fish consumption (12% for the linear model), with the possibility that additional consumption confers incremental benefits (central estimate of 2.0% per serving per week). [less ▲]

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See detailSleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients.
Diederich, Nico UL; Vaillant, Michel; Leischen, Mike et al

in Movement Disorders (2005), 20(11), 1413-8

In PD, the impact of nocturnal respiration on sleep continuity and architecture has not been systematically investigated by polysomnography (PSG). We performed a case-control study with retrospective ... [more ▼]

In PD, the impact of nocturnal respiration on sleep continuity and architecture has not been systematically investigated by polysomnography (PSG). We performed a case-control study with retrospective analysis of PSG data of 49 PD patients. After classifying the PD patients according to their apnea/hypopnea index (AHI), they were matched with 49 controls in terms of age, gender, and AHI. There were 21 PD patients (43%) who had sleep apnea syndrome (SAS), classified as mild (AHI, 5-15) in 10 patients, moderate (AHI, >15-30) in 4 patients, and severe (AHI, > 30) in 7 patients. PD patients had more deep sleep (P = 0.02) and more nocturnal awakenings (P < 0.001) than the controls. Their body mass index (BMI) was lower (P = 0.04), and they maintained a more favorable respiratory profile, with higher mean and minimal oxygen saturation values (P = 0.006 and 0.01, respectively). These differences were preserved when only considering PD patients with AHI > 15. PD patients had less obstructive sleep apneas (P = 0.035), independently from the factor AHI. Only the respiratory changes of 4 PD patients with BMI > 27 and AHI > 15 (8%) approximated those seen in the controls. At an early or middle stage of the disease, non-obese PD patients frequently have AHI values suggesting SAS, however, without the oxygen desaturation profile of SAS. Longitudinal studies of patients with such "abortive" SAS are warranted to establish if this finding reflects benign nocturnal respiratory muscle dyskinesia or constitutes a precursor sign of dysautonomia in PD. [less ▲]

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See detailInterference Robustness Aspects of Space-Time Block Code-Based Transmit Diversity
Klang, Göran; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (2005), 53(4), 12991309

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See detailDynamical binding of proline-rich peptides to their recognition domains
Gu, Wei UL; Helms, V.

in Biochimica et Biophysica Acta-Proteins and Proteomics (2005), 1754(1-2), 232-238

Recognition of proline-rich sequences plays an important role for the assembly of multi-protein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that ... [more ▼]

Recognition of proline-rich sequences plays an important role for the assembly of multi-protein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that share characteristic features. For many complex systems containing proline-rich sequences, multiple binding modes have been found by theoretical and/or experimental studies. In this review, we discuss the different binding modes as well as the correlated dynamics of the peptides and their recognition domains, and some implications to their biological functions. Further-more, we give an outlook of the systems in the context of systems biology. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailL'influence du droit européen sur la distinction des sociétés cotées et non cotées
Conac, Pierre-Henri UL

in Revue des Sociétés (2005), (1), 67-67

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See detailHigh-power SiO2/AlGaN/GaN metal-oxide-semiconductor heterostructure field-effect transistors
Kordoš, P.; Heidelberger, G.; Bernát, J. et al

in Applied Physics Letters (2005), 87(14), 143501-143504

We report on SiO2 /AlGaN/GaN metal-oxide-semiconductor heterostructure field-effect transistors MOSHFETs , which exhibit a 6.7 W/mm power density at 7 GHz. Unpassivated and SiO2-passivated heterostructure ... [more ▼]

We report on SiO2 /AlGaN/GaN metal-oxide-semiconductor heterostructure field-effect transistors MOSHFETs , which exhibit a 6.7 W/mm power density at 7 GHz. Unpassivated and SiO2-passivated heterostructure field-effect transistors HFETs were also investigated for comparison. Deposited 12 nm thick SiO2 yielded an increase of the sheet carrier density from 7.6 .10^12 to 9.2 .10^12 cm−2 and a subsequent increase of the static drain saturation current from 0.75 to 1.09 A/mm. The small-signal rf characterization of the MOSHFETs showed an extrinsic current gain cutoff frequency fT of 24 GHz and a maximum frequency of oscillation fmax of 40 GHz. The output power of 6.7 W/mm of the MOSHFETs measured at 7 GHz is about two times larger than that of HFETs. The results obtained demonstrate the suitability of GaN-based MOSHFETs for high-power electronics. [less ▲]

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See detailRhombic embeddings of planar quad-graphs
Kenyon, Richard; Schlenker, Jean-Marc UL

in Trans. Amer. Math. Soc. (2005), 357(9), 3443--3458

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See detailSingle Point Stochastic Search Algorithms for the Multi Level Lot Sizing Problem
Jeunet, Jully; Jonard, Nicolas UL

in Computers and Operations Research (2005), 32

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See detailAlternative binding modes of proline-rich peptides binding to the GYF domain
Gu, Wei UL; Kofler, M.; Antes, I. et al

in Biochemistry (2005), 44(17), 6404-6415

Recognition of proline-rich sequences plays an important role for the assembly of multiprotein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that ... [more ▼]

Recognition of proline-rich sequences plays an important role for the assembly of multiprotein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that share characteristic features. The GYF (glycine-tyrosine-phenylalanine) domain is known as a member of the superfamily of recognition domains for proline-rich sequences. Recent studies on the complexation of the CD2BP2-GYF domain with CD2 peptides showed that the peptide adopts an extended conformation and forms a polyproline type-II helix involving residues Pro4-Pro7 [Freund et al. (2002) EMBO J. 21, 5985-5995]. R/K/GxxPPGxR/K is the key signature for the peptides that bind to the GYF domain [Kofler et at. (2004) J. Biol. Chem. 279, 28292-28297]. In our combined theoretical and experimental study, we show that the peptides adopt a polyproline 11 helical conformation in the unbound form as well as in the complex. From molecular dynamics simulations, we identify a novel binding mode for the G8W mutant and the wild-type peptide (shifted by one proline in register). In contrast, the conformation of the peptide mutant H9M remains close to the experimentally derived wild-type GYF-peptide complex. Possible functional implications of this altered conformation of the bound ligand are discussed in the light of our experimental and theoretical results. [less ▲]

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See detailThe Environmental Kuznets Curve semi-parametrically revisited
Bertinelli, Luisito UL; Strobl, Eric

in Economics Letters (2005), 88(3), 350-357

This paper re-examines the existence of an Environmental Kuznets Curve (EKC) across countries using a semi-parametric regression estimator, which places no restrictions on the functional form. Our results ... [more ▼]

This paper re-examines the existence of an Environmental Kuznets Curve (EKC) across countries using a semi-parametric regression estimator, which places no restrictions on the functional form. Our results using cross-country panel data on Sulfur and Carbon Dioxide strongly suggest that the relationship between wealth and environmental degradation is not bell-shaped, as suggested by an EKC. Rather that there is a positive link for the very poorest countries and no clear relationshipfor richer countries.<P>(This abstract was borrowed from another version of this item.) [less ▲]

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See detailEchelle des attitudes professionnelles des médecins généralistes et des pharmaciens d'officine favorisant l'observance thérapeutique
Baumann, Michèle UL; Baumann, C.; Aubry, C. et al

in Revue Médicale de l'Assurance Maladie (2005), 36(1), 23-33

Objectif : Construire et valider une échelle des attitudes professionnelles des médecins généralistes (APMG) et une échelle des attitudes professionnelles des pharmaciens d’officine (APPO). Méthodes ... [more ▼]

Objectif : Construire et valider une échelle des attitudes professionnelles des médecins généralistes (APMG) et une échelle des attitudes professionnelles des pharmaciens d’officine (APPO). Méthodes : Étape 1. Construction et validation qualitative d’une échelle. Nous avons repéré, dans le discours de 40 usagers lorrains d’un centre de médecine préventive, de 21 médecins généralistes (MG), et de 22 pharmaciens d’officine (PO), les items candidats définissant le construit théorique des attitudes professionnelles intervenant dans la mise en place et le suivi des traitements des patients. Ensuite nous avons élaboré, avec un groupe d’experts, les items génériques du questionnaire permettant leur validation et identifié les fonctions que remplissent ces attitudes. Étape 2. Validation statistique de l’échelle des APMG et de l’échelle des APPO. Nous avons étudié, à l’aide d’un questionnaire auto-administré auprès de 393 usagers lorrains, les propriétés métriques de ces échelles. Résultats : Les attitudes relationnelles sont au nombre de 15 pour les MG et de neuf pour les PO. Elles sont associées aux fonctions d’information, de communication, d’éducation. Les échelles des APMG et des APPO forment deux échelles unidimensionnelles. Les analyses montrent une cohérence interne élevée (coefficient alpha de Cronbach respectivement 0,91 et 0,87) ainsi qu’une reproductibilité correcte (coefficient de corrélation intra-classe respectivement 0,74 et 0,72). Conclusion : Les compétences mises à jour représentent les critères de qualité de la relation interpersonnelle médecinusager et pharmacien-usager. Les propriétés métriques des échelles des APMG (15 items) et des APPO (neuf items) sont satisfaisantes. Ceci légitime leur utilisation comme outil d’aide : à la formation à la relation professionnel-usager ; à la décision ; à l’évaluation des compétences relationnelles. [less ▲]

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See detailEthique et humanitaire. Mise en œuvre des pratiques de consultation et de participation
Baumann, Michèle UL; Vié Le Sage, F.

in Pédiatre (Le) (2005), (211), 2-5

Au cours des dernières décennies, l’aide humanitaire a pris un essor considérable. En même temps, elle s’est trouvée confrontée à un nombre croissant de critiques dont la plus significative est celle d ... [more ▼]

Au cours des dernières décennies, l’aide humanitaire a pris un essor considérable. En même temps, elle s’est trouvée confrontée à un nombre croissant de critiques dont la plus significative est celle d'être perçue comme un système défini et imposé par l’occident, fonctionnant sur un mode « descendant » et ayant de ce fait, une capacité d’écoute sélective. Le rôle des populations touchées dans leur propre survie est l'un des défis les plus complexes auquel le monde des acteurs humanitaires doit faire face. En particulier la prise en compte des points de vue, des attentes, des besoins exprimés, des responsabilités, des compétences des populations concernées, durant tout le cycle de la gestion du projet, est une condition indispensable à l'amélioration de la réponse humanitaire vue en tant que processus de réappropriation de la part des populations de leur pouvoir d'agir sur leur vie. A cet égard, l'idée selon laquelle une implication active du public est une condition nécessaire pour assurer le caractère éthique de toute délibération et garantir l’acceptation des interventions par les populations est aujourd'hui reconnue, mais est-elle suffisante, est elle toujours possible ? [less ▲]

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See detailLa mort à Bruxelles, 1914 - 1918
Majerus, Benoît UL

in Cahiers d'Histoire du Temps Présent = Bijdragen tot de Eigentijdse Geschiedenis (2005), (15), 65--81

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See detailKörperbild, Diätverhalten und körperliche Aktivität bei 9-10 jährigen Kindern
Vögele, Claus UL; Woodward, Heidi

in Kindheit und Entwicklung (2005), 14

The aim of the present study was to investigate body dissatisfaction and eating attitudes and the moderating role of gender, parental influences, body-mass index (BMI), and physical activity in 9 ± 10 ... [more ▼]

The aim of the present study was to investigate body dissatisfaction and eating attitudes and the moderating role of gender, parental influences, body-mass index (BMI), and physical activity in 9 ± 10-year-old children. Sixty-eight 9 ± 10-year-old children (36 boys, 32 girls) were asked to indicate their perceived and ideal body size using the figure drawing scale of Childress et al. (1993). Physical activity levels were assessed with a diary method over 7 consecutive days. Questionnaires were used to collect information on children's eating habits and children's perception of parental weight, parental attitudes towards body size, and eating habits. Children's weight and height were measured and the BMI calculated. 44 % of boys and 34 % of girls wanted to be thinner than they perceived themselves to be. Multiple regression analyses indicated that this desire was predicted by children's BMI, perceived overweight of mother, and eating patterns indicating restraint eating style. Given that only 13 % were overweight, the percentage of children wanting to be thinner is of concern. The current results indicate that there may be an increasing trend for a thinner body ideal in boys compared to previous reports. [less ▲]

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See detailKennen als een vorm van handelen. John Deweys transactionele kentheorie.
Biesta, Gert UL

in Bijdragen Tijdschrift voor Filosofie en Theologie (2005), 15(1), 5-12

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See detailLa regulation américaine des agences de notation
Conac, Pierre-Henri UL

in Risques : les cahiers de l'assurance (2005), (61), 55-55

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See detailEMPReSS: standardized phenotype screens for functional annotation of the mouse genome.
Brown, S D; Chambon, P; De Angelis, M H et al

in Nature Genetics (2005), (37), 1155

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See detailPeriodic unmixing of a binary metallic vapor
Maul, J.; Strachnov, I.; Karpuk, S. et al

in Physical Review. B, Condensed Matter and Materials Physics (2005), 72(15),

We report on a type of surface structuring after short pulse laser ablation of a binary alloy. We observe the emergence of a concentric ring structure with changing elemental composition. The composition ... [more ▼]

We report on a type of surface structuring after short pulse laser ablation of a binary alloy. We observe the emergence of a concentric ring structure with changing elemental composition. The composition changes are interpreted by condensation of the ambient ablation vapor due to stress wave excitations in the ablation spot. [less ▲]

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See detailMechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
Sommer, Ulrike; Schmid, Christine; Sobota, Radoslaw M. et al

in Journal of Biological Chemistry (2005), 280(36), 31478-88

The suppressors of cytokine signaling (SOCS) are negative feedback inhibitors of cytokine signal transduction. SOCS3 is a key negative regulator of interleuking-6 (IL-6) signal transduction. Furthermore ... [more ▼]

The suppressors of cytokine signaling (SOCS) are negative feedback inhibitors of cytokine signal transduction. SOCS3 is a key negative regulator of interleuking-6 (IL-6) signal transduction. Furthermore, SOCS3 was shown to be phosphorylated upon treatment of cells with IL-2, and this has been reported to regulate its function and half-life. We set out to investigate whether SOCS3 phosphorylation may play a role in IL-6 signaling. Tyrosine-phosphorylated SOCS3 was detected upon treatment of mouse embryonic fibroblasts with IL-6. Interestingly, the observed SOCS3 phosphorylation does not require SOCS3 recruitment to phosphotyrosine (Tyr(P)) 759 of gp130, and the kinetics of SOCS3 phosphorylation do not match the activation kinetics of the Janus kinases. This suggests that other kinases may be involved in SOCS3 phosphorylation. Using Src and Janus kinase inhibitors as well as Src kinase-deficient mouse embryonic fibroblasts, we provide evidence that Src kinases, which we found to be constitutively active in these cells, are involved in the phosphorylation of IL-6-induced SOCS3. In addition, we found that receptor-tyrosine kinases such as platelet-derived growth factor receptor or epidermal growth factor receptor can very potently phosphorylate IL-6-induced SOCS3. Taken together, these results suggest that SOCS3 phosphorylation is not a JAK-mediated phenomenon but is dependent on the activity of other kinases such as Src kinases or receptor-tyrosine kinases, which can either be constitutively active or activated by an additional stimulus. [less ▲]

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See detailDas Problem des Wahrheitskriteriums. Zu Hegels Auseinandersetzung mit der skeptischen Aporie des Maßstabs
Heidemann, Dietmar UL

in Kritisches Jahrbuch der Philosophie (2005), 10

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See detailDetailed characterization of (3X3) iodine adlayer on Pt(111) by unequal-sphere packing model
Tkatchenko, Alexandre UL; Batina, Nikola

in JOURNAL OF CHEMICAL PHYSICS (2005), 122(9),

A simple unequal-sphere packing model is applied to study the iodine (3x3) adlayer on the Pt(111) surface. By using a newly introduced parameter, defined as the average adsorbate height, three ... [more ▼]

A simple unequal-sphere packing model is applied to study the iodine (3x3) adlayer on the Pt(111) surface. By using a newly introduced parameter, defined as the average adsorbate height, three characteristic adlattices, (3x3)-sym, (3x3)-asym, and (3x3)-lin, have been selected and characterized in great detail, including the exact adatom registry. The (3x3)-sym iodine adlattice, observed in many experimental studies appears to be, on average, the closest one to the substrate surface. A special contour plot of average adsorbate height vs X and Y positions of the (3x3) iodine unit cell indicates the existence of two local minima which are related to preferential formation of (3x3)-sym and (3x3)-asym iodine adlattices. Our model gives good agreement with experimental findings, and explains the mechanism of preferential appearance of (3x3)-sym and (3x3)-asym structures. (C) 2005 American Institute of Physics. [less ▲]

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See detailDeutsch-Französische Grenzräume als interkulturelle Schnittstellen. Wirtschaftliche Zusammenarbeit im Raum Saarland-Lothringen
Wille, Christian UL

in Dokumente : Zeitschrift für den deutsch-französischen Dialog = Documents : revue du dialogue franco-allemand (2005), (1), 24-28

Nationale Grenzen verlieren durch die zunehmende Verflechtung europäischer Volkswirtschaften ihre trennende Wirkung, und die Zahl der Geschäftskontakte über Länderund Kulturgrenzen hinweg wächst stetig ... [more ▼]

Nationale Grenzen verlieren durch die zunehmende Verflechtung europäischer Volkswirtschaften ihre trennende Wirkung, und die Zahl der Geschäftskontakte über Länderund Kulturgrenzen hinweg wächst stetig. Eine transnationale Wirtschaftswelt öffnet aber nicht nur neue Handlungsräume, sie erfordert auch die Fähigkeit, mit Angehörigen anderer Kulturen kommunizieren und zusammenarbeiten zu können.... [less ▲]

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See detailOptimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing.
Bauer, Sebastian; Maier, Sebastian K. G.; Neyses, Ludwig UL et al

in DNA and cell biology (2005), 24(6), 381-7

Cardiomyocytes are notoriously difficult to transfect using standard techniques unless viral vectors such as recombinant adenoviruses are used. Generation of recombinant adenoviruses is, however, a ... [more ▼]

Cardiomyocytes are notoriously difficult to transfect using standard techniques unless viral vectors such as recombinant adenoviruses are used. Generation of recombinant adenoviruses is, however, a complex and time-consuming procedure and not possible for every DNA construct. We therefore optimized DNA/polylysine/adenovirus complexing for efficient gene transfer in neonatal rat cardiomyocytes determining the critical parameters for this method. Importantly, not only the concentration of the various components but also the method used for plasmid purification is critical for this transfection technique. Cesium-chloride-purified DNA is inferior to anion-exchange methods for this purpose possibly because of altered ionic properties. In the second part of this study, we could demonstrate silent gene transfer into cardiomyocytes applying this optimized technique to plasmids encoding luciferase or beta-galactosidase cDNAs under the control of the cytomegalovirus immediate-early promoter. Phorbol myristate acetate and/or forskolin increased the amount of beta-galactosidase positive cells up to fivefold. Luciferase activity could even be increased as much as ninefold. These results demonstrate that the cytomegalovirus promoter is not maximally active in neonatal rat cardiomyocytes under basal conditions. In fact, a large proportion of cells is silently transfected and seems to express (an) inhibitor(s) of transcription from the CMV promoter that can be overcome by stimulation of cAMP- or protein kinase C-dependent pathways. [less ▲]

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See detailArray Interpolation and DOA MSE Reduction
Hyberg, Per; Jansson, Magnus; Ottersten, Björn UL

in IEEE Transactions on Signal Processing (2005), 53(12), 44644471

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See detailDer Einfluss von Expertise auf den Prozess der schulischen Leistungsbeurteilung
Krolak-Schwerdt, Sabine UL; Rummer, Ralf

in Zeitschrift für Entwicklungspsychologie und Padagogische Psychologie (2005), 37

Two experiments investigated the effects of information processing goals on the recall of information about pupils and on achievement judgments. In Experiment 1 teachers (experts) were presented with case ... [more ▼]

Two experiments investigated the effects of information processing goals on the recall of information about pupils and on achievement judgments. In Experiment 1 teachers (experts) were presented with case reports about pupils. The reports were either read under the instruction (a) to form an impression of the personality of the described pupils or (b) to predict their future development. Afterwards subjects had to recall the case reports and to rate the academic achievement of the described pupils. Experiment 2 was a replication with university freshmen (laymen) as subjects. Depending on their processing goal, experts switched their processing of pupil information from top-down strategies involving the activation of prototypical categories about pupil personalities to bottom-up processing which consists of integrating the features of the individual case. Thus, processing goals appear as moderators in teachers’ judgments. [less ▲]

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See detailGeneration of frustrated liquid crystal phases by mixing an achiral n–smc mesogen with an antiferroelectric chiral smectic liquid crystal
Lagerwall, Jan UL; Giesselmann, Frank; Selbmann, Christine et al

in Journal of Chemical Physics (2005), 122(14), 144906

By mixing the achiral liquid crystal HOAB, exhibiting a nematic (N)-smectic-C (SmC) mesophase sequence, with the chiral antiferroelectric liquid crystal (AFLC) (S,S)-M7BBM7, forming the antiferroelectric ... [more ▼]

By mixing the achiral liquid crystal HOAB, exhibiting a nematic (N)-smectic-C (SmC) mesophase sequence, with the chiral antiferroelectric liquid crystal (AFLC) (S,S)-M7BBM7, forming the antiferroelectric SmCa phase, at least seven different mesophases have been induced which neither component forms on its own: a twist-grain-boundary (TGB) phase, two or three blue phases, the untilted SmA phase, as well as all three chiral smectic-C-type ``subphases,'' SmCalpha, SmCbeta, and SmCgamma. The nature of the induced phases and the transitions between them were determined by means of optical and electro-optical investigations, dielectric spectroscopy, and differential scanning calorimetry. The induced phases can to a large extent be understood as a result of frustration, TGB at the border between nematic and smectic, the subphases between syn and anticlinic tilted smectic organization. X ray scattering experiments reveal that the smectic layer spacing as well as the degree of smectic order is relatively constant in the whole mixture composition range in which AFLC behavior prevails, whereas both these parameters rapidly decrease as the amount of HOAB is increased to such an extent that no other smectic-C-type phase than SmC/SmC exists. By tailoring the composition we are able to produce liquid crystal mixtures exhibiting unusual phase sequences, e.g., with a direct isotropic-SmCa transition or a temperature range of the SmCbeta subphase of about 50 K. (C) 2005 American Institute of Physics. [less ▲]

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See detailA Reply to the Comment by A. Rivera et al.
Krüger, Jan-Kristian UL; Britz, Thomas; Baller, Jörg UL et al

in Physical Review Letters (2005), 94

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See detailWhen will smart antennas be ready for the market? Part II - results
Kaiser, T.; Bourdoux, A.; Choi, S. et al

in IEEE Signal Processing Magazine (2005), 22(6), 174176

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See detailImaging of microwave-induced acoustic fields in LiNbO3 by high-performance Brillouin microscopy
Vincent, B.; Krüger, Jan-Kristian UL; Elmazria, Omar et al

in Journal of Physics : D Applied Physics (2005), 38(12), 2026-2030

High performance Brillouin microscopy (BM) has been used to characterize the spatial distribution of piezoelectrically induced acoustic fields excited at microwave frequencies in a LiNbO3 single crystal ... [more ▼]

High performance Brillouin microscopy (BM) has been used to characterize the spatial distribution of piezoelectrically induced acoustic fields excited at microwave frequencies in a LiNbO3 single crystal. It is demonstrated that under suitable conditions BM is able to detect microwave-induced bulk as well as surface acoustic waves. Brillouin spectroscopy is able to probe sound wave intensities of induced phonons, which are as small as those of thermal phonons. [less ▲]

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See detailA study of a bistereogenic mesogen for the development of orthoconic antiferroelectric liquid crystal materials
Lagerwall, Jan UL; Yates, Chris; Rauch, Sebastian et al

in Ferroelectrics (2005), 315

The first orthoconic antiferroetectric liquid crystals (OAFLCs), i.e. smectics where the optical director changes direction by 90 degrees between neighboring layers, were mixtures of partially fluorinated ... [more ▼]

The first orthoconic antiferroetectric liquid crystals (OAFLCs), i.e. smectics where the optical director changes direction by 90 degrees between neighboring layers, were mixtures of partially fluorinated monostereogenic compounds. They have successfully demonstrated the orthoconic properties (orientation-independent dark state between crossed polarizers) but suffer from too high polarization and too short helical pitch, necessitating very thin samples. Using an (S,R) bistereogenic OAFLC we have obtained the orientation-independent dark state in rather thick samples, but several other problems arise with this compound. The strongly first-order SmA-SmCa transition produces defects leading to light leakage. In order to be switchable the sample must furthermore be mixed with chiral dopants, generally reducing the tilt angle as well as a shortening the helical pitch. Finally, a SmC phase often appears in the phase sequence of the mixture, strongly dominating over the desired SmCa phase in thin cells. [less ▲]

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See detailA cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery.
Noor, Fozia UL; Wustholz, Annette; Kinscherf, Ralf et al

in Angewandte Chemie International Edition (2005), 44(16), 2429-32

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See detailLe contrat d'appui au projet d'entreprise pour la création ou la reprise d'une activité économique
Hiez, David UL

in Bulletin Joly Sociétés (2005), 12

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See detailPseudopath semiclassical approximation to transport through open quantum billiards: Dyson equation for diffractive scattering
Stampfer, C.; Rotter, S.; Burgdorfer, J. et al

in Physical Review. E. (2005), 72(3),

We present a semiclassical theory for transport through open billiards of arbitrary convex shape that includes diffractively scattered paths at the lead openings. Starting from a Dyson equation for the ... [more ▼]

We present a semiclassical theory for transport through open billiards of arbitrary convex shape that includes diffractively scattered paths at the lead openings. Starting from a Dyson equation for the semiclassical Green's function we develop a diagrammatic expansion that allows a systematic summation over classical and pseudopaths, the latter consisting of classical paths joined by diffractive scatterings ("kinks"). This renders the inclusion of an exponentially proliferating number of pseudopath combinations numerically tractable for both regular and chaotic billiards. For a circular billiard and the Bunimovich stadium the path sum leads to a good agreement with the quantum path length power spectrum up to long path length. Furthermore, we find excellent numerical agreement with experimental studies of quantum scattering in microwave billiards where pseudopaths provide a significant contribution. [less ▲]

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