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See detail2 Notare, 1 Hauptversammlung
Zetzsche, Dirk Andreas UL; Reul, A.

in Aktiengesellschaft (Die) (2007)

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See detail2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes
Carballeira, N. M.; Bwalya, A. G.; Itoe, M. A. et al

in Bioorganic & Medicinal Chemistry Letters (2014), 24(17), 4151-4157

The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this study ... [more ▼]

The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this study, we investigated a series of 2-alkynoic fatty acids (2-AFAs) with chain lengths between 14 and 18 carbon atoms for dual in vitro activity against both life stages. 2-Octadecynoic acid (2-ODA) was identified as the best inhibitor of Plasmodium berghei parasites with ten times higher potency (IC50 = 0.34 μg/ml) than the control drug. In target determination studies, the same compound inhibited three Plasmodium falciparum FAS-II (PfFAS-II) elongation enzymes PfFabI, PfFabZ, and PfFabG with the lowest IC50 values (0.28-0.80 μg/ml, respectively). Molecular modeling studies provided insights into the molecular aspects underlying the inhibitory activity of this series of 2-AFAs and a likely explanation for the considerably different inhibition potentials. Blood stages of P. falciparum followed a similar trend where 2-ODA emerged as the most active compound, with 20 times less potency. The general toxicity and hepatotoxicity of 2-AFAs were evaluated by in vitro and in vivo methods in mammalian cell lines and zebrafish models, respectively. This study identifies 2-ODA as the most promising antiparasitic 2-AFA, particularly towards P. berghei parasites. © 2014 Elsevier Ltd. All rights reserved. [less ▲]

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See detail2-stage process for a higher flexibility of biogas-plants
Greger, Manfred UL; Benito-Martins, Patricia; Schlienz, Markus UL

Scientific Conference (2016, September 21)

The increasing part of renewable energy in the electricity production mix with its known fluctuations of wind and photovoltaic plants is leading to an enlarged discrepancy of production and consumption ... [more ▼]

The increasing part of renewable energy in the electricity production mix with its known fluctuations of wind and photovoltaic plants is leading to an enlarged discrepancy of production and consumption. Up to now the electricity production of biogas plants is more or less constant but could be used in future more to balance the energy production by using higher biogas storage capacity. An interesting alternative could be a 2 stage process. The 1st stage is operated at higher loadings and low pH where mainly substrate hydrolysis takes place and relatively small quantities of H2/CO2 gas are produced. The effluent shows high concentrations (total > 10 g FA/l) of mainly butyric and caproic acid which could easily and stable be temporarily stored in liquid-tanks. The transformation of the acidic intermediates from hydrolysis to biogas (and finally electricity) in the 2nd stage is faster compared to the traditional fermentation. The storage capacity for the acidic intermediates is more than 10 times smaller compared to the temporary storage of biogas. [less ▲]

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See detailLes 20 ans de la Cour Constitutionnelle: trop jeune pour mourir?
Gerkrath, Jörg UL

Book published by Pasicrisie luxembourgeoise (2018)

Celebrating 20 years of existence of the court, the volume evaluates the past and future of the constitutional court of Luxembourg. The first part is dedicated to the achievements of 20 years os case law ... [more ▼]

Celebrating 20 years of existence of the court, the volume evaluates the past and future of the constitutional court of Luxembourg. The first part is dedicated to the achievements of 20 years os case law. The second part focuses on the question whether the constitutional court should be replaced by a supreme court as it was suggested by a government proposal. [less ▲]

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See detail20 Jahre Verbundbauforschung an der Universität Kaiserslautern
Joachim, Hans; Stengel, Jochen; Odenbreit, Christoph UL et al

in Stahlbau (2013), 69(10), 788--806

Nach zwanzig Jahren aktiver Lehr‐ und Forschungstätigkeit als Inhaber des Lehrstuhls für Stahlbau an der Universität Kaiserslautern hat sich Prof. Dr.‐Ing. H. Bode in diesem Sommer aus gesundheitlichen ... [more ▼]

Nach zwanzig Jahren aktiver Lehr‐ und Forschungstätigkeit als Inhaber des Lehrstuhls für Stahlbau an der Universität Kaiserslautern hat sich Prof. Dr.‐Ing. H. Bode in diesem Sommer aus gesundheitlichen Gründen aus Lehre und Forschung zurückziehen müssen. Als ehemaliger Mitarbeiter von Prof. Dr.‐Ing. K. Roik, Ruhr‐Universität Bochum, brachte Prof. Bode bei seiner Berufung im November 1980 den Stahlverbundbau, der von da an der Schwerpunkt seiner Forschungsarbeiten wurde, nach Kaiserslautern. Dieser Aufsatz soll einen kurzen Abriß und zugleich einen Überblick über abgeschlossene und laufende Forschungsarbeiten geben. [less ▲]

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See detail200 Jahre Großherzogtum
Pauly, Michel UL

Article for general public (2015)

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See detailThe 2004 Afghan Constitution and Islam Merits and Challenges
Al Hajjaji, Shams Al Din UL

Scientific Conference (2019, November 11)

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See detailThe 2005 Riots in France: The International Impact of Domestic Violence
Koff, Harlan UL; Duprez, Dominique

in JOURNAL OF ETHNIC AND MIGRATION STUDIES (2009), 35(5), 713-730

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See detail2005-2015: Des référendums créateurs d'identité
Scuto, Denis UL

Article for general public (2015)

Weekly column on contemporary history ("L'histoire du temps présent") in Luxembourg newspaper Tageblatt, here on the referenda of 2005 on the European Constitutional Treaty and of 2015 on the right to ... [more ▼]

Weekly column on contemporary history ("L'histoire du temps présent") in Luxembourg newspaper Tageblatt, here on the referenda of 2005 on the European Constitutional Treaty and of 2015 on the right to vote on national elections in Luxembourg for foreigners [less ▲]

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See detail2009-2010: Poland, Germany and Russia remember World War II
Venken, Machteld UL

Presentation (2010)

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See detail2010 -­‐ Perspektiven ökologischer Stadtgestaltung
Hesse, Markus UL

in European Urban & Regional Studies (1994), 1(2), 189-190

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See detailThe 2011 European short sale ban: A cure or a curse?,
Kräussl, Roman UL; Felix, Luiz; Stork, Philip

in Journal of Financial Stability (2016)

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See detailThe 2011 European Short Sale Ban: An Option Market Perspective
Kräussl, Roman UL

E-print/Working paper (2014)

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See detail2015 Lab report - Legato report 001
Bordas, Stéphane UL

Report (2016)

Detailed reference viewed: 477 (12 UL)
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See detail2015 Workshop on Socio-Technical Aspects in Security and Trust, STAST 2015, Verona, Italy, July 13, 2015
Bella, Giampaolo; Lenzini, Gabriele UL

Scientific Conference (2015, July 13)

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See detail2017 AIChE Annual Meeting
Qi, Fenglei UL; Wright, Mark

in Qi, Fenglei; Wright, Mark (Eds.) A DEM modeling of biomass fast pyrolysis in a double screw reactor (2017, October 31)

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See detail2018 25th International Conference on Telecommunications (ICT)
Lagunas, Eva UL; Chatzinotas, Symeon UL; Ottersten, Björn UL

in 2018 25th International Conference on Telecommunications (ICT) (2018)

The anticipated exponential growth in network traffic is posing significant challenges for the implementation of 5G networks. In this context, a major problem is the backhaul network which acts as a ... [more ▼]

The anticipated exponential growth in network traffic is posing significant challenges for the implementation of 5G networks. In this context, a major problem is the backhaul network which acts as a bottleneck preventing the efficient flow of ultra-dense and heavy traffic between the end users and the core network. Spectrum scarcity has emerged as the primary problem encountered when trying to accommodate the traffic upsurge. In this paper, we investigate the carrier allocation problem in the context of Integrated Satellite-Terrestrial Backhaul (ISTB) networks. In particular, we consider the satellite component to be integrated with the conventional terrestrial wireless backhaul network thus providing evident benefits in terms of data-offloading. To enhance the overall spectral efficiency of the proposed network, we consider that both terrestrial and satellite segments operate in the Ka band, where the sharing between terrestrial microwave links and satellite communications is already allowed. A novel carrier allocation algorithm based on fairness is proposed, which ensures that all backhaul links are continuously active to satisfy the operator's coverage needs. The problem is NP-hard by definition. As a consequence, we present a two-step sequential carrier allocation strategy specifically tailored to tackle the interference issues emerging from the spectral co-existence. Supporting results based on numerical simulations show that the proposed carrier allocation can provide a 2x improvement in terms of spectral efficiency when compared to benchmark terrestrial-only backhaul networks. [less ▲]

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See detail2018 IEEE 23rd International Workshop on Computer Aided Modeling and Design of Communication Links and Networks (CAMAD)
Domouchtsidis, Stavros; Tsinos, Christos UL; Chatzinotas, Symeon UL et al

in 2018 IEEE 23rd International Workshop on Computer Aided Modeling and Design of Communication Links and Networks (CAMAD) (2018)

Large-Scale Antenna Array Systems may be used to serve multiple users in the same time-frequency resource block which results to harmful multi-user interference (MUI). In the literature precoding ... [more ▼]

Large-Scale Antenna Array Systems may be used to serve multiple users in the same time-frequency resource block which results to harmful multi-user interference (MUI). In the literature precoding techniques have been proposed as a way to mitigate the induced MUI, by designing the transmitted signals using the knowledge of the Channel State Information (CSI), in block-level precoding (BLP) or both the CSI and the information-bearing symbols, in symbol-level precoding (SLP). However, the proposed SLP techniques require fully digital baseband processing which is infeasible in large-scale antenna array systems because of the high cost and power consumption of radio frequency (RF) components. In order to reduce the number of y-RF chains, we address an Antenna Selection Symbol-Level Precoding (AS-SLP) scheme, which minimizes the MUI by activating only a subset of the available antennas. For this scheme we develop an efficient algorithm, based on Coordinate Descent. Simulations provide an insight on the efficiency of the proposed approach and its improvement with respect to the fully digitally approaches. [less ▲]

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