Trick with Treat – Reciprocity increases the willingness to communicate personal data.

Scientific Conference (2016, June)

Information security is a significant challenge for information and communication technologies (ICT). This includes withstanding attempts of social engineering aimed at manipulating people into divulging ... [more ▼]

Information security is a significant challenge for information and communication technologies (ICT). This includes withstanding attempts of social engineering aimed at manipulating people into divulging confidential information. However, many users are lacking awareness of the risks involved with, for example, password security. In a field survey that tested reciprocal behavior in social interactions, 1,208 participants were asked to reveal their personal password. More than one third of the participants shared their password with an unknown interviewer. In line with the social norm of reciprocity, people were more willing to do so when they received a small incentive (i.e., a piece of chocolate) before they were asked to reveal personal information. Elicitation was even more successful when the incentive was given right before asking for the password. The results, including moderating factors (e.g., age, gender), are discussed in the light of security awareness of ICT users and the mechanisms of psychological persuasion. [less ▲]

A Tridimensional Approach for Studying the Formal Verification of Model Transformations

in Proceedings of the First Workshop on Verification and Validation of Model Transformations (2012)

TRIGGER: A Lightweight Universal Jamming Gripper for Aerial Grasping

in IEEE Access (2023)

Triggers, topics and conditions of self-education in non-formal settings – Results of an empirical study in the context of youth work

Presentation (2022, June 19)

Trigonometry for the multiples of 3 degrees

Article for general public (2019)

Trigraph

in Neef, Martin; Weingarten, Rüdiger (Eds.) Schriftlinguistik (2019)

Trilingual Primary Education in Luxembourg

in Bangma, Idske; van der Meer, Cor; Riemersma, Alex (Eds.) Trilingual Primary Education in Europe - Some developments with regard to the provisions of trilingual primary education in minority language communities of the European Union (2011)

Trillingen tijdens het boren van de Hubertustunnel

in Geotechniek (2009)

Tijdens het boren van de Hubertustunnel in Den Haag zijn geen schadelijke trillingen opgetreden, maar wel onverwachte hinderlijke trillingen. Bij het boorproces in bijvoorbeeld rotsformaties zijn ... [more ▼]

Tijdens het boren van de Hubertustunnel in Den Haag zijn geen schadelijke trillingen opgetreden, maar wel onverwachte hinderlijke trillingen. Bij het boorproces in bijvoorbeeld rotsformaties zijn dergelijke trillingen bekend, maar men had dit niet verwacht in het hier aanwezige strandzand. Uit analyse van de gemeten trillingen blijkt dat de trillingen voornamelijk zijn ontstaan door de stroeve voortgang van de TBM in het zand ten gevolge van het stick-slip effect. Het vooruit schokken van de TBM veroorzaakt hoofdzakelijk trillingen in boorrichting: schuifgolven langs de wand en drukgolven aan het boorfront. [less ▲]

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.

in Cell (2009), 136(5), 913-25

In the mouse neocortex, neural progenitor cells generate both differentiating neurons and daughter cells that maintain progenitor fate. Here, we show that the TRIM-NHL protein TRIM32 regulates protein ... [more ▼]

In the mouse neocortex, neural progenitor cells generate both differentiating neurons and daughter cells that maintain progenitor fate. Here, we show that the TRIM-NHL protein TRIM32 regulates protein degradation and microRNA activity to control the balance between those two daughter cell types. In both horizontally and vertically dividing progenitors, TRIM32 becomes polarized in mitosis and is concentrated in one of the two daughter cells. TRIM32 overexpression induces neuronal differentiation while inhibition of TRIM32 causes both daughter cells to retain progenitor cell fate. TRIM32 ubiquitinates and degrades the transcription factor c-Myc but also binds Argonaute-1 and thereby increases the activity of specific microRNAs. We show that Let-7 is one of the TRIM32 targets and is required and sufficient for neuronal differentiation. TRIM32 is the mouse ortholog of Drosophila Brat and Mei-P26 and might be part of a protein family that regulates the balance between differentiation and proliferation in stem cell lineages. [less ▲]

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration.

in PLoS ONE (2012), 7(1), 30445

Limb girdle muscular dystrophy type 2H (LGMD2H) is an inherited autosomal recessive disease of skeletal muscle caused by a mutation in the TRIM32 gene. Currently its pathogenesis is entirely unclear ... [more ▼]

Limb girdle muscular dystrophy type 2H (LGMD2H) is an inherited autosomal recessive disease of skeletal muscle caused by a mutation in the TRIM32 gene. Currently its pathogenesis is entirely unclear. Typically the regeneration process of adult skeletal muscle during growth or following injury is controlled by a tissue specific stem cell population termed satellite cells. Given that TRIM32 regulates the fate of mammalian neural progenitor cells through controlling their differentiation, we asked whether TRIM32 could also be essential for the regulation of myogenic stem cells. Here we demonstrate for the first time that TRIM32 is expressed in the skeletal muscle stem cell lineage of adult mice, and that in the absence of TRIM32, myogenic differentiation is disrupted. Moreover, we show that the ubiquitin ligase TRIM32 controls this process through the regulation of c-Myc, a similar mechanism to that previously observed in neural progenitors. Importantly we show that loss of TRIM32 function induces a LGMD2H-like phenotype and strongly affects muscle regeneration in vivo. Our studies implicate that the loss of TRIM32 results in dysfunctional muscle stem cells which could contribute to the development of LGMD2H. [less ▲]